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    Expression System, Components Thereof and Methods of Use
    2.
    发明申请
    Expression System, Components Thereof and Methods of Use 有权
    表达系统及其组件及其使用方法

    公开(公告)号：US20080311618A1

    公开(公告)日：2008-12-18

    申请号：US11575621

    申请日：2005-10-03

    申请人： Yan Xu ,  Alaka Mullick ,  Bernard Massie

    发明人： Yan Xu ,  Alaka Mullick ,  Bernard Massie

    IPC分类号： C12N15/11 ,  C07K14/00 ,  C12N5/10

    CPC分类号： C07K14/21

    摘要： Recently, the development of inducible expression systems has involved exploitation of the p-cym operon from Pseudomonas putido. Disclosed herein are novel expression systems and components thereof, which involve the development of CymR variants with reverse DNA binding activity, such that they exhibit increased affinity for DNA in a presence rather than an absence of an effector molecule such as cumene or an equivalent thereof. Also disclosed are the CymR variants, fusion proteins incorporating such variants, and their use in the control and expression of polynucleotides.

    摘要翻译： 最近，诱导型表达系统的发展涉及从假单胞菌（Pseudomonas putido）中开发p-cym操纵子。 本文公开了新的表达系统及其组分，其涉及开发具有反向DNA结合活性的CymR变体，使得它们在存在而不是不存在效应分子例如枯烯或其等同物时表现出对DNA的增加的亲和力。 还公开了CymR变体，掺入这些变体的融合蛋白及其在多核苷酸的控制和表达中的用途。

    Reverse cumate repressor mutant
    3.
    发明授权
    Reverse cumate repressor mutant 有权
    反向并发阻遏物突变体

    公开(公告)号：US08728759B2

    公开(公告)日：2014-05-20

    申请号：US11575621

    申请日：2005-10-03

    申请人： Yan Xu ,  Alaka Mullick ,  Bernard Massie

    发明人： Yan Xu ,  Alaka Mullick ,  Bernard Massie

    IPC分类号： C12P21/06 ,  C12P21/04 ,  C12N15/00 ,  C12N5/00 ,  C12N5/04 ,  C07K14/00 ,  C07H21/04

    CPC分类号： C07K14/21

    摘要： Recently, the development of inducible expression systems has involved exploitation of the p-cym operon from Pseudomonas putida. Disclosed herein are novel expression systems and components thereof, which involve the development of CymR variants with reverse DNA binding activity, such that they exhibit increased affinity for DNA in a presence rather than an absence of an effector molecule such as cumene or an equivalent thereof. Also disclosed are the CymR variants, fusion proteins incorporating such variants, and their use in the control and expression of polynucleotides.

    摘要翻译： 最近，诱导型表达系统的发展涉及从恶臭假单胞菌（Pseudomonas putida）中开发p-cym操纵子。 本文公开了新的表达系统及其组分，其涉及开发具有反向DNA结合活性的CymR变体，使得它们在存在而不是不存在效应分子例如枯烯或其等同物时表现出对DNA的增加的亲和力。 还公开了CymR变体，掺入这些变体的融合蛋白及其在多核苷酸的控制和表达中的用途。

    Mirror
    4.
    外观设计
    Mirror 有权

    公开(公告)号：USD950965S1

    公开(公告)日：2022-05-10

    申请号：US29720973

    申请日：2020-01-16

    申请人： Yan Xu

    设计人： Yan Xu

    NANOMETER-PRECISION SIX-DEGREE-OF-FREEDOM MAGNETIC SUSPENSION MICRO-MOTION TABLE AND APPLICATION THEREOF
    7.
    发明申请
    NANOMETER-PRECISION SIX-DEGREE-OF-FREEDOM MAGNETIC SUSPENSION MICRO-MOTION TABLE AND APPLICATION THEREOF 有权
    NANOMETER-PRECISION六自由度磁悬浮微运动表及其应用

    公开(公告)号：US20130038853A1

    公开(公告)日：2013-02-14

    申请号：US13635168

    申请日：2011-03-15

    申请人： Yu Zhu ,  Ming Zhang ,  Guang Li ,  Jinsong Wang ,  Jinchun Hu ,  Wensheng Yin ,  Kaiming Yang ,  Li Zhang ,  Jing Ma ,  Yan Xu ,  Yujie Li ,  Li Tian ,  Guanghong Duan

    发明人： Yu Zhu ,  Ming Zhang ,  Guang Li ,  Jinsong Wang ,  Jinchun Hu ,  Wensheng Yin ,  Kaiming Yang ,  Li Zhang ,  Jing Ma ,  Yan Xu ,  Yujie Li ,  Li Tian ,  Guanghong Duan

    IPC分类号： H02K41/02 ,  G03B27/58

    CPC分类号： G03F7/70758 ,  G03F7/70716

    摘要： A nanometer precision six-DOF magnetic suspension micro-stage and the application thereof are provided which are mainly used in semiconductor photolithography devices. The micro-stage includes a cross support and four two-DOF actuators. Each 2-DOF actuator comprises a vertically polarized permanent magnet, a horizontal force coil and a vertical force coil; the permanent magnet being mounted on an end of the cross support, the horizontal force coil and the vertical force coil being arranged on a side of and below the permanent magnet respectively and being spaced apart from the permanent magnet; the cross support and four vertically polarized permanent magnets constitute a mover of the micro-stage; the horizontal force coil and the vertical force coil being fixed by a coil framework respectively and constituting a stator of the micro-stage; and the stator being mounted on a base of the micro-stage. A dual-wafer table positioning system of a photolithography machine may be constructed by two said micro-stages in combination with a two-DOF large stroke linear motor. The present invention features simple structure, large driving force, small mass and absence of cable disturbance, and is possible to realize high precision, high acceleration six-DOF micro-motion.

    摘要翻译： 提供了主要用于半导体光刻设备的纳米精密六自由度磁悬浮微步及其应用。 微型平台包括十字支架和四个双自由度执行器。 每个2-DOF致动器包括垂直极化永磁体，水平力线圈和垂直力线圈; 所述永磁体安装在所述十字支架的一端上，所述水平力线圈和所述垂直力线圈分别设置在所述永久磁铁的一侧和下方并与所述永磁体隔开; 交叉支撑和四个垂直极化永磁体构成微型载物; 水平力线圈和垂直力线圈分别由线圈框架固定并构成微型定子; 并且定子安装在微型台的基座上。 光刻机的双晶片台定位系统可以由两个微步与二自由度大行程直线电机组合构成。 本发明结构简单，驱动力大，质量小，无电缆扰动，可实现高精度，高加速度六自由度微动作。

    RING LIGHT SOURCE SYSTEM FOR INTERFEROMETER WITH ADJUSTABLE RING RADIUS AND RING RADIAL WIDTH
    8.
    发明申请
    RING LIGHT SOURCE SYSTEM FOR INTERFEROMETER WITH ADJUSTABLE RING RADIUS AND RING RADIAL WIDTH 有权
    具有可调节环的干涉仪的环形光源系统RADIUS和环径向宽度

    公开(公告)号：US20130027942A1

    公开(公告)日：2013-01-31

    申请号：US13558572

    申请日：2012-07-26

    申请人： Yan Xu ,  Yongjian Wan ,  Yongqian Wu

    发明人： Yan Xu ,  Yongjian Wan ,  Yongqian Wu

    IPC分类号： F21V5/04

    CPC分类号： G01B9/02001 ,  G02B27/0944

    摘要： A ring light source system for an interferometer with adjustable ring radius and ring radial width may comprise a laser light source, an expander and collimator optical system, an adjustable aperture, a binary phase grating, a variable-focus optical system, and a spatial filter. The expander and collimator optical system is configured to convert a light beam from the light source into a parallel light beam. The adjustable aperture is configured to adjust a diameter of the parallel light beam. The light beam with the diameter adjusted by the adjustable aperture is incident perpendicularly onto the binary phase grating, followed by the variable-focus optical system. The filter is positioned on a back focal plane of the variable-focus optical system, and is configured to receive a ring light source. The ring radius and radial width of the light source are adjustable by adjusting a focus length f1 of the variable-focus optical system.

    摘要翻译： 用于具有可调节环半径和环径向宽度的干涉仪的环形光源系统可以包括激光源，扩展器和准直器光学系统，可调节孔径，二进制相位光栅，可变焦距光学系统和空间滤波器 。 扩展器和准直器光学系统被配置为将来自光源的光束转换成平行光束。 可调整孔径被配置为调节平行光束的直径。 具有由可调孔径调节的直径的光束垂直入射到二进制相位光栅上，随后是可变焦光学系统。 滤光器位于可变焦光学系统的后焦平面上，并且被配置为接收环形光源。 通过调整可变焦光学系统的焦距f1可以调节光源的环半径和径向宽度。

    POWER SWITCH CIRCUIT
    9.
    发明申请
    POWER SWITCH CIRCUIT 失效
    电源开关电路

    公开(公告)号：US20110298524A1

    公开(公告)日：2011-12-08

    申请号：US12838485

    申请日：2010-07-18

    申请人： Yan Xu ,  Yan-Ling Geng ,  Hui Yin ,  Bo-Ching Lin ,  Han-Che Wang

    发明人： Yan Xu ,  Yan-Ling Geng ,  Hui Yin ,  Bo-Ching Lin ,  Han-Che Wang

    IPC分类号： H03K17/60 ,  H03K17/687 ,  H03K17/00

    CPC分类号： H02M3/156

    摘要： A power switch circuit providing voltage to an output port is provided. The switch circuit includes a single power supply, a switch unit, a controlling unit, and a logic unit. The switch unit is connected between the single power supply and an output port and capable of being turned on and off alternatively for continuing or discontinuing power from the single power supply to the output port; the single power supply provides power to the output port. The controlling unit is configured for generating a voltage controlling signal and transmitting the voltage controlling signal to the logic unit. The logic unit receives and inverts the voltage controlling signal, and outputs the inverted voltage controlling signal to turn on or turn off the switch unit.

    摘要翻译： 提供向输出端口提供电压的电源开关电路。 开关电路包括单个电源，开关单元，控制单元和逻辑单元。 开关单元连接在单个电源和输出端口之间，并且能够交替地被接通和断开，用于从单个电源向输出端口继续或停止电力; 单个电源为输出端口提供电源。 控制单元被配置为产生电压控制信号并将电压控制信号传送到逻辑单元。 逻辑单元接收和反相电压控制信号，并输出反相电压控制信号以接通或关断开关单元。