Macrocyclic proline derived HCV serine protease inhibitors
    3.
    发明授权
    Macrocyclic proline derived HCV serine protease inhibitors 有权
    大环脯氨酸衍生的HCV丝氨酸蛋白酶抑制剂

    公开(公告)号:US08648037B2

    公开(公告)日:2014-02-11

    申请号:US13237120

    申请日:2011-09-20

    IPC分类号: A61K38/00 A01N37/18

    摘要: The present invention discloses compounds of Formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

    摘要翻译: 本发明公开了式I化合物或其药学上可接受的盐,酯或前药:其抑制丝氨酸蛋白酶活性,特别是丙型肝炎病毒(HCV)NS3-NS4A蛋白酶的活性。 因此,本发明的化合物干扰丙型肝炎病毒的生命周期,也可用作抗病毒剂。 本发明还涉及药物组合物,其包含用于给患有HCV感染的受试者施用的上述化合物。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的HCV感染的方法。

    Mixed structures of single walled and multi walled carbon nanotubes
    6.
    发明授权
    Mixed structures of single walled and multi walled carbon nanotubes 有权
    单壁和多壁碳纳米管的混合结构

    公开(公告)号:US09126828B2

    公开(公告)日:2015-09-08

    申请号:US11841676

    申请日:2007-08-20

    摘要: The invention relates to carbon nanotube structures containing both single walled and multi walled carbon nanotubes, and methods for preparing same. These carbon nanotube structures include but are not limited to macroscopic two and three dimensional structures of carbon nanotubes such as assemblages, mats, plugs, networks, rigid porous structures, extrudates, etc. The carbon nanotube structures of the present invention have a variety of uses, including but not limited to, porous media for filtration, adsorption, chromatography; electrodes and current collectors for supercapacitors, batteries and fuel cells; catalyst supports, (including electrocatalysis), etc.

    摘要翻译: 本发明涉及含有单壁和多壁碳纳米管的碳纳米管结构及其制备方法。 这些碳纳米管结构包括但不限于碳纳米管的宏观二维和三维结构,例如组合物,垫,塞子,网络,刚性多孔结构,挤出物等。本发明的碳纳米管结构具有多种用途 包括但不限于用于过滤,吸附,色谱的多孔介质; 用于超级电容器,电池和燃料电池的电极和集电器; 催化剂载体(包括电催化)等

    Water vapor control structure
    7.
    发明授权
    Water vapor control structure 有权
    水汽控制结构

    公开(公告)号:US08950849B2

    公开(公告)日:2015-02-10

    申请号:US13371937

    申请日:2012-02-13

    申请人: Andrew W. Hays Jun Ma

    发明人: Andrew W. Hays Jun Ma

    IPC分类号: B41J2/045 B41J2/175

    CPC分类号: B41J2/14233

    摘要: In some aspects of the present application, an inkjet printing device is disclosed that can comprises an enclosed module configured to store ink and provide a path for ink flow; and an annular structure surrounding the path for ink flow, wherein the annular structure comprises a first polymer structure; a void structure arranged to surround the first polymer structure; and a second polymer structure arranged to surround the void structure.

    摘要翻译: 在本申请的一些方面,公开了一种喷墨打印装置,其可以包括被配置为存储墨水并提供油墨流动路径的封闭模块; 以及围绕所述油墨流动路径的环形结构,其中所述环形结构包括第一聚合物结构; 布置成围绕第一聚合物结构的空隙结构; 以及布置成围绕所述空隙结构的第二聚合物结构。

    High density three-dimensional electrical interconnections
    8.
    发明授权
    High density three-dimensional electrical interconnections 有权
    高密度三维电互连

    公开(公告)号:US08888254B2

    公开(公告)日:2014-11-18

    申请号:US13614879

    申请日:2012-09-13

    IPC分类号: B41J2/045

    摘要: Implementations relate to methods, devices produced by the method, and systems using the devices, for forming three-dimensional interconnect structures for ink piezoelectric printheads. A piezoelectric element array for an ink jet print head can include a plurality of piezoelectric elements spaced from adjacent piezoelectric elements by an interstitial space. Each piezoelectric element can include a central void space formed in a first intermediate layer between the piezoelectric element array and a second intermediate layer that is operable to function as a free space for portions of the piezoelectric elements to actuate into when subjected to the voltage.

    摘要翻译: 实现涉及通过该方法产生的方法,使用该装置的系统,用于形成油墨压电打印头的三维互连结构。 用于喷墨打印头的压电元件阵列可以包括通过间隙空间与相邻的压电元件间隔开的多个压电元件。 每个压电元件可以包括形成在压电元件阵列和第二中间层之间的第一中间层中的中心空隙空间,该第二中间层可操作地用作自由空间,用于部分压电元件在受到电压时致动。

    Processes for the recovery of catalytic metal and carbon nanotubes
    9.
    发明授权
    Processes for the recovery of catalytic metal and carbon nanotubes 有权
    回收催化金属和碳纳米管的方法

    公开(公告)号:US08852547B2

    公开(公告)日:2014-10-07

    申请号:US12358772

    申请日:2009-01-23

    申请人: Jun Ma Robert Hoch

    发明人: Jun Ma Robert Hoch

    摘要: A new method for recovering a catalytic metal and carbon nanotubes from a supported catalyst is provided. The carbon nanotube, including carbon nanotube structures, may serve as the support for the catalytic metal. The valence state of the catalytic metal, if not already in the positive state, is raised to a positive state by contacting the supported catalyst with a mild oxidizing agent under conditions which does not destroy the carbon nanotube. The supported catalyst is simultaneously or subsequently contacted with an acid solution to dissolve the catalytic metal without dissolving the carbon nanotube.

    摘要翻译: 提供了一种从负载催化剂中回收催化金属和碳纳米管的新方法。 包括碳纳米管结构在内的碳纳米管可以用作催化金属的载体。 在不破坏碳纳米管的条件下,通过使负载型催化剂与温和氧化剂接触,将催化金属的价态(如果尚未处于正态)升高至正态。 负载的催化剂同时或随后与酸溶液接触以溶解催化金属而不溶解碳纳米管。