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    METHOD FOR OBSERVING PROTEIN CRYSTAL
    4.
    发明申请
    METHOD FOR OBSERVING PROTEIN CRYSTAL 有权
    观察蛋白水晶的方法

    公开(公告)号：US20130184445A1

    公开(公告)日：2013-07-18

    申请号：US13825280

    申请日：2011-09-20

    申请人： Norihiko Nishizawa ,  Hiroyoshi Matsumura ,  Yuusuke Mori ,  Shutaro Ishida ,  Kazuyoshi Itoh ,  Shigeru Sugiyama ,  Hiroaki Adachi ,  Tsuyoshi Inoue ,  Kazufumi Takano ,  Murakami Satoshi

    发明人： Norihiko Nishizawa ,  Hiroyoshi Matsumura ,  Yuusuke Mori ,  Shutaro Ishida ,  Kazuyoshi Itoh ,  Shigeru Sugiyama ,  Hiroaki Adachi ,  Tsuyoshi Inoue ,  Kazufumi Takano ,  Murakami Satoshi

    IPC分类号： G01B9/02 ,  C07K1/30

    CPC分类号： G01B9/02091 ,  C07K1/306 ,  G01N21/4795 ,  G01N2021/1787

    摘要： Provided are a method for observing protein crystal, wherein the growth process of the protein crystals is nondestructively and three-dimensionally monitored on a real-time basis and the growth of the crystals is controlled at a high accuracy to thereby enable the formation of single crystals having good qualities, which comprises observing the protein crystals, said protein crystals having been produced by a crystallization method using a gel, by an OCT measurement using light emitted from an ultrawideband light source;a method for observing protein crystals wherein the ultrawideband light source is an ultrawideband supercontinuum light source; a method for observing protein crystals wherein the center wavelength of the light emitted from the ultrawideband supercontinuum light source is a 0.8 μm band; and a method for observing protein crystals wherein the monitoring of the protein crystals is a monitoring by an in situ measurement.

    摘要翻译： 提供了一种用于观察蛋白质晶体的方法，其中蛋白质晶体的生长过程以实时的方式非破坏性和三维地监测，并且以高精度控制晶体的生长，从而能够形成单晶 具有良好的质量，其包括通过使用从超宽带光源发射的光的OCT测量观察蛋白质晶体，所述蛋白质晶体是通过使用凝胶的结晶方法产生的; 一种观察蛋白质晶体的方法，其中超宽带光源是超宽带超连续光源; 观察蛋白质晶体的方法，其中从超宽带超连续光源发射的光的中心波长为0.8μm波段; 以及观察蛋白质晶体的方法，其中蛋白质晶体的监测是通过原位测量的监测。

    Method for observing protein crystal
    7.
    发明授权
    Method for observing protein crystal 有权
    观察蛋白质晶体的方法

    公开(公告)号：US09182216B2

    公开(公告)日：2015-11-10

    申请号：US13825280

    申请日：2011-09-20

    申请人： Norihiko Nishizawa ,  Hiroyoshi Matsumura ,  Yuusuke Mori ,  Shutaro Ishida ,  Kazuyoshi Itoh ,  Shigeru Sugiyama ,  Hiroaki Adachi ,  Tsuyoshi Inoue ,  Kazufumi Takano ,  Murakami Satoshi

    发明人： Norihiko Nishizawa ,  Hiroyoshi Matsumura ,  Yuusuke Mori ,  Shutaro Ishida ,  Kazuyoshi Itoh ,  Shigeru Sugiyama ,  Hiroaki Adachi ,  Tsuyoshi Inoue ,  Kazufumi Takano ,  Murakami Satoshi

    IPC分类号： G01B9/02 ,  G01N21/47 ,  C07K1/30 ,  G01N21/17

    CPC分类号： G01B9/02091 ,  C07K1/306 ,  G01N21/4795 ,  G01N2021/1787

    摘要： Provided are a method for observing protein crystal, wherein the growth process of the protein crystals is nondestructively and three-dimensionally monitored on a real-time basis and the growth of the crystals is controlled at a high accuracy to thereby enable the formation of single crystals having good qualities, which comprises observing the protein crystals, said protein crystals having been produced by a crystallization method using a gel, by an OCT measurement using light emitted from an ultrawideband light source;a method for observing protein crystals wherein the ultrawideband light source is an ultrawideband supercontinuum light source;a method for observing protein crystals wherein the center wavelength of the light emitted from the ultrawideband supercontinuum light source is a 0.8 μm band; anda method for observing protein crystals wherein the monitoring of the protein crystals is a monitoring by an in situ measurement.

    摘要翻译： 提供了一种用于观察蛋白质晶体的方法，其中蛋白质晶体的生长过程以实时的方式非破坏性和三维地监测，并且以高精度控制晶体的生长，从而能够形成单晶 具有良好的质量，其包括通过使用从超宽带光源发射的光的OCT测量观察蛋白质晶体，所述蛋白质晶体是通过使用凝胶的结晶方法产生的; 一种观察蛋白质晶体的方法，其中超宽带光源是超宽带超连续光源; 观察从超宽带超连续光源发射的光的中心波长为0.8μm波段的蛋白质晶体的方法; 以及观察蛋白质晶体的方法，其中蛋白质晶体的监测是通过原位测量的监测。

    Optical fiber coupling part and manufacturing method thereof
    8.
    发明授权
    Optical fiber coupling part and manufacturing method thereof 有权
    光纤耦合部件及其制造方法

    公开(公告)号：US07603008B2

    公开(公告)日：2009-10-13

    申请号：US10569279

    申请日：2005-02-01

    申请人： Hiroyoshi Matsumura ,  Taro Suzuki ,  Toru Achiwa

    发明人： Hiroyoshi Matsumura ,  Taro Suzuki ,  Toru Achiwa

    IPC分类号： G02B6/32

    CPC分类号： G02B6/4206 ,  G02B3/0087 ,  G02B6/2551 ,  G02B6/30

    摘要： An optical fiber coupling part that reduces the difficulty in adjusting cores, minimizes coupling loss, and prevents optical characteristics from deteriorating. An optical fiber is fused to one end of a GRIN lens which includes a quartz glass containing one or more refractive index regulating substances selected from Sb2O3, Ta2O5, TiO2 or ZrO2. Optical characteristics are not deteriorated because an adhesive is not used, and self-alignment effects facilitate adjustment of the cores of the GRIN lens and the optical fiber. Furthemore, coupling loss can be minimized by setting a refractive index distribution constant g of the GRIN lens within an appropriate range.

    摘要翻译： 一种光纤耦合部件，其减小了对芯的调节困难，使耦合损耗最小化，防止光学特性恶化。 将光纤熔合到GRIN透镜的一端，其包括含有选自Sb 2 O 3，Ta 2 O 5，TiO 2或ZrO 2中的一种或多种折射率调节物质的石英玻璃。 由于不使用粘合剂，光学特性不会劣化，自对准效果有利于GRIN透镜和光纤的芯的调节。 通过将GRIN透镜的折射率分布常数g设定在适当的范围内，可以减少耦合损耗。

    Optical switch and optical add/drop multiplexer
    9.
    发明授权
    Optical switch and optical add/drop multiplexer 失效
    光开关和光分插复用器

    公开(公告)号：US07343064B2

    公开(公告)日：2008-03-11

    申请号：US11541783

    申请日：2006-10-02

    申请人： Etsuo Koyama ,  Hiroyoshi Matsumura

    发明人： Etsuo Koyama ,  Hiroyoshi Matsumura

    IPC分类号： G02B6/34 ,  G02B6/35 ,  G02F1/13

    CPC分类号： G02F1/133553 ,  G02F1/216 ,  G02F1/2955 ,  G02F2201/307 ,  G02F2203/055 ,  G02F2203/585

    摘要： To provide a wavelength-selection optical switch able to select a light with a certain wavelength and an optical add/drop multiplexer using the same. An optical switch comprising: a silicon substrate; a glass substrate arranged to face a surface of the silicon substrate and having a transparent electrode layer in its opposing surface; a light diffraction reflection layer aligned on a surface of the silicon substrate; a liquid crystal layer aligned between the light diffraction reflection layer and the transparent electrode layer; a silicon substrate electrical terminal extracted from a rear surface of the silicon substrate; and a means for applying voltage between the transparent electrode layer and the silicon substrate electrical terminal; wherein selection of wavelength of light diffracted and reflected by the light diffraction reflection layer is possible by controlling the refraction index of the liquid crystal layer through the voltage. A beam diameter of a wavelength multiplexed light signal is widened by a collimator lens, the wavelength multiplexed light signal with widened beam diameter is directed to the optical switch, a light signal which has wavelength selected through the applied voltage on the optical switch is only diffracted and reflected by the optical switch.

    摘要翻译： 提供能够选择具有一定波长的光的波长选择光学开关和使用其的光学分插复用器。 一种光开关，包括：硅衬底; 玻璃基板，其布置成面对硅基板的表面并且在其相对表面中具有透明电极层; 在硅衬底的表面上对准的光衍射反射层; 在所述光衍射反射层和所述透明电极层之间排列的液晶层; 从硅衬底的后表面提取的硅衬底电端子; 以及用于在所述透明电极层和所述硅衬底电端子之间施加电压的装置; 其中通过控制液晶层的折射率通过该电压，可以选择由光衍射反射层衍射和反射的光的波长。 波长复用光信号的光束直径被准直透镜加宽，光束直径变宽的波长复用光信号被引导到光开关，通过光开关上的施加电压选择的波长的光信号仅被衍射 并由光开关反射。