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    Process for producing crystalline nucleus and method of screening crystallization conditions
    3.
    发明授权
    Process for producing crystalline nucleus and method of screening crystallization conditions 失效
    生产晶核的方法和筛选结晶条件的方法

    公开(公告)号：US07247203B2

    公开(公告)日：2007-07-24

    申请号：US10525809

    申请日：2003-08-25

    申请人： Takatomo Sasaki ,  Yusuke Mori ,  Masashi Yoshimura ,  Hiroaki Adachi ,  Hiroshi Masuhara ,  Youichiroh Hosokawa ,  Kazufumi Takano

    发明人： Takatomo Sasaki ,  Yusuke Mori ,  Masashi Yoshimura ,  Hiroaki Adachi ,  Hiroshi Masuhara ,  Youichiroh Hosokawa ,  Kazufumi Takano

    IPC分类号： C30B29/54

    CPC分类号： C30B7/00 ,  C30B29/58 ,  Y10S117/904

    摘要： The present invention relates to a process for producing high-quality crystals of protein or organic substances easily and efficiently. A solution of protein or an organic substance is prepared and then is cooled slowly to be supersaturated to a low degree. This supersaturated solution is irradiated with a femtosecond laser 10. A local explosion phenomenon occurs at the focal point of the laser and thereby a crystalline nucleus is generated. A high-quality crystal is obtained when a crystal is grown on the crystalline nucleus over a long period of time. The femtosecond laser to be used herein can be a titanium:sapphire laser having a wavelength of 800 nm, a duration of 120 fs, a frequency of 1 kHz, and an output of 400 mW.

    摘要翻译： 本发明涉及容易高效地生产蛋白质或有机物质的优质晶体的方法。 制备蛋白质或有机物质的溶液，然后缓慢冷却至低饱和度。 用飞秒激光10照射该过饱和溶液。 在激光的焦点发生局部爆炸现象，从而产生晶核。 当晶体长时间在晶核上生长时，获得高质量的晶体。 本文使用的飞秒激光可以是波长为800nm，持续时间为120fs，频率为1kHz，输出为400mW的钛：蓝宝石激光。

    Method for analyzing sample in liquid
    5.
    发明授权
    Method for analyzing sample in liquid 有权
    分析液体样品的方法

    公开(公告)号：US08037739B2

    公开(公告)日：2011-10-18

    申请号：US12197108

    申请日：2008-08-22

    申请人： Masahiro Ota ,  Noriaki Oyabu ,  Hiroaki Adachi ,  Masayuki Abe ,  Seizo Morita ,  Yusuke Mori ,  Takatomo Sasaki

    发明人： Masahiro Ota ,  Noriaki Oyabu ,  Hiroaki Adachi ,  Masayuki Abe ,  Seizo Morita ,  Yusuke Mori ,  Takatomo Sasaki

    IPC分类号： G01N11/00

    CPC分类号： G01Q30/14 ,  G01N1/36 ,  G02B21/33 ,  G02B21/34

    摘要： A method for analyzing a sample in a liquid is provided, which is suitable for easily and reliably preventing a liquid for analysis from being evaporated. When the sample in the liquid is observed by using a scanning probe microscope (SPM), a sealing liquid (17) immiscible with a liquid for analysis (16) is filled around the liquid for analysis (16), in which a sample (13) and a probe (15) are immersed, so as to form a sealing state, in which the liquid for analysis (16) is isolated from an external gas. The SPM enables the probe (15) disposed on a front end of a cantilever (14) to approach a surface of the sample (13) immersed in the liquid, scans the surface of the sample, and detects an interaction between the sample (13) and the probe (15), thereby generating an image.

    摘要翻译： 提供一种用于分析液体中的样品的方法，其适于容易且可靠地防止用于分析的液体蒸发。 当使用扫描探针显微镜（SPM）观察液体中的样品时，将用于分析的液体（16）不混溶的密封液体（17）填充在用于分析的液体（16）周围，其中样品（13 ）和探针（15），以便形成用于分析用液体（16）与外部气体隔离的密封状态。 SPM使得布置在悬臂（14）的前端上的探针（15）接近浸入液体中的样品（13）的表面，扫描样品的表面，并检测样品（13）之间的相互作用 ）和探头（15），从而产生图像。

    Digital data processor
    7.
    发明授权
    Digital data processor 有权
    数字数据处理器

    公开(公告)号：US08443017B2

    公开(公告)日：2013-05-14

    申请号：US12758198

    申请日：2010-04-12

    申请人： Ryoji Suzuki ,  Yusuke Mori

    发明人： Ryoji Suzuki ,  Yusuke Mori

    IPC分类号： G06F7/00

    CPC分类号： G11B20/10527 ,  G06F5/01 ,  G10L21/0364

    摘要： A digital data processor which receives an N-bit input signal from a data source and converts the N-bit input signal into an M-bit output signal, the M-bit being larger than the N-bit. The digital data processor includes: an weighted addition circuit which is operable to perform weighted addition on at least the input signal and a signal being time-shifted with respect to the input signal and output as a weighted added input signal; an arithmetic shift circuit which is operable to perform an arithmetic rightward shift operation on the weighted added input signal for a predetermined number of shifts and output as a processed input signal; a bit extension circuit which is operable to attach a predetermined bits to an LSD side of the input signal to generate an intermediate signal of M bits; and an addition circuit which is operable to perform addition of the intermediate signal and the processed input signal so as to generate the M-bit output signal.

    摘要翻译： 数字数据处理器，其从数据源接收N位输入信号，并将N位输入信号转换成M位输出信号，M位大于N位。 所述数字数据处理器包括：加权加法电路，其可操作以至少对所述输入信号执行加权相加，以及相对于所述输入信号进行时移的信号，并作为加权相加输入信号输出; 算术移位电路，其可操作以对所述加权的相加输入信号执行预定数量的移位并作为经处理的输入信号输出的算术右移移位操作; 一个扩展电路，用于将预定的比特附加到输入信号的LSD侧，以产生M比特的中间信号; 以及加法电路，其可操作以执行中间信号和经处理的输入信号的相加以便产生M位输出信号。

    Substrate treating apparatus and substrate treating method
    8.
    发明授权
    Substrate treating apparatus and substrate treating method 有权
    基板处理装置及基板处理方法

    公开(公告)号：US08372299B2

    公开(公告)日：2013-02-12

    申请号：US12411266

    申请日：2009-03-25

    申请人： Yasunori Nakajima ,  Yusuke Mori

    发明人： Yasunori Nakajima ,  Yusuke Mori

    IPC分类号： C03C15/00

    CPC分类号： B08B3/08 ,  B08B3/048

    摘要： A method and apparatus for performing treatment of substrates with a treating liquid. A first storage unit stores an initial life count specifying an allowable number of treatments of substrates to be carried out with treating liquid after an entire liquid replacement with a new supply of the treating liquid; a second storage device stores a normal life count specifying an allowable number of treatments to be carried out with the treating liquid after reaching the initial life count and after a partial liquid replacement; and a control device repeats treatment of the substrates after the entire liquid replacement until the initial life count is reached; and after the initial life count has been reached and the partial liquid replacement has been made, repeats treatment of the substrates until the normal life count is reached, and makes the partial liquid replacement each succeeding time the normal life count is reached.

    摘要翻译： 一种用处理液进行基材处理的方法和装置。 第一存储单元存储初始寿命数，其指定在处理液的新供应之后，在整个液体置换之后，用待处理液进行处理的基板的允许数量; 第二存储装置在达到初始寿命计数之后和在部分液体置换之后存储指定要用处理液进行的处理的允许数量的正常寿命计数; 并且控制装置在整个液体置换之后重复对基板的处理，直到达到初始寿命计数; 在达到初始寿命计数并进行部分液体置换之后，重复对基板的处理，直到达到正常寿命计数，并且在随后的时间达到正常寿命计数之后进行部分液体置换。

    Method of classifying and counting leukocytes
    10.
    发明授权
    Method of classifying and counting leukocytes 有权
    白细胞分类和计数方法

    公开(公告)号：US07923229B2

    公开(公告)日：2011-04-12

    申请号：US11926918

    申请日：2007-10-29

    申请人： Tomohiro Tsuji ,  Toshihiro Mizukami ,  Aya Konishi ,  Yusuke Mori ,  Yukie Nakazawa

    发明人： Tomohiro Tsuji ,  Toshihiro Mizukami ,  Aya Konishi ,  Yusuke Mori ,  Yukie Nakazawa

    IPC分类号： C12N13/00

    CPC分类号： G01N33/52 ,  G01N2015/1477

    摘要： A method for classifying and counting leukocytes, which comprises steps of: staining cells in a sample obtained from a hematological sample by treatment with a hemolytic agent, with a fluorescent dye; introducing the sample containing the stained cells into a flow cytometer to measure first scattered light, second scattered light different from the first scattered light and fluorescence of the respective cells; obtaining scattered light peak intensities and scattered light widths of the respective cells based on the measured first scattered light, obtaining scattered light intensities of the respective cells based on the measured second scattered light, and obtaining fluorescence intensities of the respective cells based on the measured fluorescence light; classifying the cells into a first group and a second group based on the scattered light peak intensities and the scattered light widths, the first group including leukocytes and second group including platelet clumps; classifying the leukocytes included in the first group into at least lymphocytes, monocytes and granulocytes based on the scattered light intensities and the fluorescence intensities; and counting the classified lymphocytes, the classified monocytes and the classified granulocytes.

    摘要翻译： 一种白细胞分类和计数方法，其特征在于包括以下步骤：用溶血剂用荧光染料染色从血液样品中获得的样品中的细胞; 将含有染色细胞的样品引入流式细胞仪中以测量第一散射光，与第一散射光不同的第二散射光和各细胞的荧光; 基于所测量的第一散射光获得各个单元的散射光峰强度和散射光宽度，基于测量的第二散射光获得各个单元的散射光强度，并且基于测量的荧光获得各个单元的荧光强度 光; 基于散射光峰强度和散射光宽度将细胞分类为第一组和第二组，第一组包括白细胞和第二组包括血小板聚集; 基于散射光强度和荧光强度，将第一组中包含的白细胞分类为至少淋巴细胞，单核细胞和粒细胞; 并对分类的淋巴细胞，分类的单核细胞和分类的粒细胞进行计数。