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    HUMAN HEALING ABILITY ENHANCING APPARATUS AND METHOD FOR ACTUATING HUMAN HEALING ABILITY ENHANCING APPARATUS
    2.
    发明申请
    HUMAN HEALING ABILITY ENHANCING APPARATUS AND METHOD FOR ACTUATING HUMAN HEALING ABILITY ENHANCING APPARATUS 有权
    人体健康能力增强装置和促进人体健康能力提高装置的方法

    公开(公告)号：US20120266874A1

    公开(公告)日：2012-10-25

    申请号：US13505919

    申请日：2010-11-22

    申请人： Yukichika Kawakami ,  Masayuki Niwa

    发明人： Yukichika Kawakami ,  Masayuki Niwa

    IPC分类号： A61G10/02

    CPC分类号： A61G10/023 ,  A61H33/066 ,  A61H33/14 ,  A61H2033/143 ,  A61H2201/50

    摘要： A human healing ability enhancing apparatus includes an airtight part that is capable of being airtight; a decompression pump that decompresses air pressure in the airtight part and communicates with an exhaust port of the airtight part; and an over-decompression prevention device for preventing over-decompression in which the air pressure in the airtight part is lower than a predetermined threshold air pressure. The apparatus that can favorably provide a stimulus for enhancing healing capacity of a living body by a decompression control means sequentially and repeatedly controls a decompressing process in which air pressure in the airtight part that is capable of being airtight is changed to a decompression state that is equal to or higher than the threshold air pressure during 1 to 60 minute(s), and a pressurizing process in which the decompression state is changed to a wide-range normal pressure state that is a normal pressure or a pressure higher than the decompression state and lower than the normal pressure during 1 to 60 minute(s) can be obtained.

    摘要翻译： 人体愈合能力增强装置包括能够气密的气密部分; 减压泵，其对所述气密部中的气压进行减压，并与所述气密部的排气口连通; 以及用于防止气密部分中的空气压力低于预定阈值空气压力的过度减压的过减压装置。 可以有利地提供用于通过减压控制装置提高生物体的愈合能力的刺激的装置，并且反复地控制减压过程，其中气密部分中的能够气密的气压被改变为减压状态，即， 等于或高于阈值空气压力在1至60分钟内的加压过程，并且其中减压状态变为作为常压或高于减压状态的压力的大范围常压状态 并能够在1〜60分钟内低于正常压力。

    Polyglycolic acid-based resin composition and shaped product thereof
    3.
    发明授权
    Polyglycolic acid-based resin composition and shaped product thereof 有权
    聚乙醇酸系树脂组合物及其成型体

    公开(公告)号：US07179868B2

    公开(公告)日：2007-02-20

    申请号：US10548646

    申请日：2004-03-19

    申请人： Kazuyuki Yamane ,  Hiroyuki Sato ,  Yukichika Kawakami

    发明人： Kazuyuki Yamane ,  Hiroyuki Sato ,  Yukichika Kawakami

    IPC分类号： C08L67/04 ,  C08F20/02

    CPC分类号： B32B27/36 ,  C08L67/02 ,  C08L67/04 ,  C08L2666/18

    摘要： A polyglycolic acid-based resin composition is formed by adding a relatively small amount of aromatic polyester resin to a polyglycolic acid resin. The thus-formed composition is provided with remarkably improved moisture resistance stability and hot-melt processability, and further improved stretchability, while retaining the excellent properties as represented by gas barrier property of the polyglycolic acid resin. As a result of stretching by utilizing the improved stretchability, a shaped product having an improved transparency can be obtained.

    摘要翻译： 通过将相对少量的芳族聚酯树脂加入到聚乙醇酸树脂中来形成聚乙醇酸类树脂组合物。 提供如此形成的组合物具有显着改进的耐湿稳定性和热熔加工性，并且进一步提高拉伸性，同时保持由聚乙醇酸树脂的阻气性表示的优异性能。 通过利用改进的拉伸性进行拉伸的结果，可以获得具有改善的透明度的成形制品。

    Polyhydroxycarboxylic acid and its production process
    4.
    发明授权
    Polyhydroxycarboxylic acid and its production process 有权
    聚羟基羧酸及其生产工艺

    公开(公告)号：US07067611B2

    公开(公告)日：2006-06-27

    申请号：US10483039

    申请日：2002-07-05

    申请人： Kazuyuki Yamane ,  Yukichika Kawakami

    发明人： Kazuyuki Yamane ,  Yukichika Kawakami

    IPC分类号： C08G63/02

    CPC分类号： C08G63/80 ,  C08G63/08

    摘要： Polyhydroxycarhoxylic acids are provided, which are controlled in terms of the rate of biodegradability, and give molded or otherwise formed articles that are of uniform quality with neither premature strength drop nor premature deterioration of retention of outside shape, and their production process is provided as well. The poly-hydroxycarboxylic acids are obtained by ring-opening polymerization of cyclic esters. The polyhydroxy-carboxylic acids have a weight-average molecular weight (Mw) in the range of 10,000 to 1,000,000, a molecular weight distribution in the range of 1.0 to 2.5 as represented by the weight-average molecular weight-to-number-average molecular weight ratio (Mw/Mn) and a yellowness index (YI) of 40 or less, and have a precisely controlled rate of biodegradability.

    摘要翻译： 提供了多羟基甲氧基酸，其以生物降解性的速率进行控制，并且得到具有均匀质量的成型制品或其它成型制品，既不过早强度下降也不会使外部形状保持力过早劣化，并且还提供其制造方法 。 多羟基羧酸通过环状酯的开环聚合得到。 多羟基羧酸的重均分子量（Mw）为10,000〜1,000,000，分子量分布范围为1.0〜2.5，以重均分子量与数均分子量 重量比（Mw / Mn）和黄色指数（YI）为40以下，具有精确控制的生物降解率。

    Process for the preparation of cyclic esters and method for purification of the same
    5.
    发明授权
    Process for the preparation of cyclic esters and method for purification of the same 有权
    环酯的制备方法及其纯化方法

    公开(公告)号：US06916939B2

    公开(公告)日：2005-07-12

    申请号：US10344461

    申请日：2001-08-08

    申请人： Kazuyuki Yamane ,  Yukichika Kawakami ,  Hajime Hoshi ,  Kazuhiko Sunagawa

    发明人： Kazuyuki Yamane ,  Yukichika Kawakami ,  Hajime Hoshi ,  Kazuhiko Sunagawa

    IPC分类号： C07D319/12

    CPC分类号： C08J3/28 ,  C07D319/12 ,  C08J11/24 ,  C08J2300/14 ,  C08J2367/04 ,  Y02W30/706

    摘要： The present invention provides a process for production of a cyclic ester by depolymerization of an aliphatic polyester. In the process, a mixture containing the aliphatic polyester and a specific polyalkylene glycol ether, which has a boiling point of 230-450° C. and a molecular weight of 150-450, is heated under normal or reduced pressure to a temperature at which depolymerization of the aliphatic polyester takes place. Then, a substantially homogeneous solution phase, consisting of the melt phase of the aliphatic polyester and the liquid phase of the polyalkylene glycol ether, is formed. Heating of the solution phase is continued to form the cyclic ester by depolymerization and distil out the cyclic ester together with the polyalkylene glycol ether, and then the cyclic ester is recovered from the distillate. The present invention also provides a process for purification of a crude cyclic ester by use of the specific polyalkylene glycol ether described above.

    摘要翻译： 本发明提供了通过脂肪族聚酯的解聚制备环状酯的方法。 在该方法中，将含有脂族聚酯和特定的聚亚烷基二醇醚的混合物在沸点为230-450℃，分子量为150-450的条件下，在正常或减压下加热至 发生脂肪族聚酯的解聚。 然后，形成由脂肪族聚酯的熔融相和聚亚烷基二醇醚的液相组成的基本均匀的溶液相。 溶液相的加热继续通过解聚形成环酯，并与聚亚烷基二醇醚一起蒸馏出环状酯，然后从馏出物中回收环状酯。 本发明还提供了通过使用上述特定的聚亚烷基二醇醚来纯化粗环酯的方法。

    Process for producing aromatic sulfide polymers
    9.
    发明授权
    Process for producing aromatic sulfide polymers 失效
    生产芳香族硫化物聚合物的方法

    公开(公告)号：US4495332A

    公开(公告)日：1985-01-22

    申请号：US517837

    申请日：1983-07-27

    申请人： Zenya Shiiki ,  Yo Iizuka ,  Yukichika Kawakami

    发明人： Zenya Shiiki ,  Yo Iizuka ,  Yukichika Kawakami

    IPC分类号： C08F2/16 ,  C08G75/02

    CPC分类号： C08G75/0254

    摘要： A process for obtaining aromatic sulfide polymer which has a markedly high molecular weight and can be readily formed into films, fibers, and other structures. The process comprises heating, in an aprotic solvent to a temperature of 100.degree. to 250.degree. C., (i) a dihaloaromatic compound and (ii) substantially anhydrous fine powder of the sulfide of an alkali or alkaline earth metal in the presence of (iii) substantially anhydrous fine powder of the carbonate of an alkali or alkaline earth metal, or of a mixture thereof with a hygroscopic inorganic salt and (iv) a strictly controlled very small amount of water dissolved in or solvated with the solvent.

    摘要翻译： 一种获得具有显着高分子量并可容易地形成薄膜，纤维和其它结构的芳香族硫化物聚合物的方法。 该方法包括在非质子溶剂中加热至100-250℃的温度，（i）二卤代芳族化合物和（ii）碱金属或碱土金属的硫化物的基本上无水的细粉末，在（ iii）碱性或碱土金属碳酸盐或其吸湿性无机盐的混合物的基本上无水的细粉末和（iv）严格控制的非常少量的溶于溶剂或溶剂化的水。

    Controlled release formulations using intelligent polymers
    10.
    发明申请
    Controlled release formulations using intelligent polymers 审中-公开
    使用智能聚合物的控制释放配方

    公开(公告)号：US20050214368A1

    公开(公告)日：2005-09-29

    申请号：US11109067

    申请日：2005-04-19

    申请人： Yukichika Kawakami ,  Nobuo Sato ,  Mitsuru Hoshino ,  Toshitaka Kouyama ,  Zenya Shiiki

    发明人： Yukichika Kawakami ,  Nobuo Sato ,  Mitsuru Hoshino ,  Toshitaka Kouyama ,  Zenya Shiiki

    IPC分类号： A61K9/14 ,  A61K9/20 ,  A61K9/22 ,  A61K9/28 ,  A61K31/716

    CPC分类号： A61K9/2846 ,  A61K9/2054 ,  A61K9/2077 ,  A61K31/716

    摘要： A controlled release pharmaceutical composition comprises (a) at least one pharmaceutically active substance having a water contact angle (θ) such that cos θ is between +0.9848 and −0.9848, (b) a first intelligent polymer component; and (c) a second intelligent polymer component having opposite wettability characteristics to the first intelligent polymer component, the first and second polymer components being present in a ratio in the range of about 1:100 to about 100:1 by weight. The polymer components are effective for controlled release of the pharmaceutically active substance from the composition.

    摘要翻译： 控释药物组合物包含（a）至少一种具有水接触角（θ）的药物活性物质，使得cosθ在+ 0.9848和-0.9848之间，（b）第一智能聚合物组分; 和（c）具有与第一智能聚合物组分相反润湿特性的第二智能聚合物组分，第一和第二聚合物组分以约1:100至约100:1重量比的比例存在。 聚合物组分对于从组合物中控制释放药物活性物质是有效的。