-
公开(公告)号：US20060030618A1
公开(公告)日：2006-02-09
申请号：US11100272
申请日：2005-04-05
申请人： Yunxin Bo , Partha Chakrabarti , Ning Chen , Elizabeth Doherty , Christopher Fotsch , Nianhe Han , Michael Kelly , Qingyian Liu , Mark Norman , Vassil Ognyanov , Xianghong Wang , Jiawang Zhu
发明人： Yunxin Bo , Partha Chakrabarti , Ning Chen , Elizabeth Doherty , Christopher Fotsch , Nianhe Han , Michael Kelly , Qingyian Liu , Mark Norman , Vassil Ognyanov , Xianghong Wang , Jiawang Zhu
IPC分类号： A61K31/353 , C07D319/08
CPC分类号： C07D471/04 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14
摘要： Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
-
公开(公告)号：US20050272931A1
公开(公告)日：2005-12-08
申请号：US11099978
申请日：2005-04-05
申请人： Yunxin Bo , Partha Chakrabarti , Ning Chen , Elizabeth Doherty , Christopher Fotsch , Nianhe Han , Michael Kelly , Qingyian Liu , Mark Norman , Vassil Ognyanov , Xianghong Wang , Jiawang Zhu
发明人： Yunxin Bo , Partha Chakrabarti , Ning Chen , Elizabeth Doherty , Christopher Fotsch , Nianhe Han , Michael Kelly , Qingyian Liu , Mark Norman , Vassil Ognyanov , Xianghong Wang , Jiawang Zhu
IPC分类号： C07D249/18 , A61K31/17 , A61K31/18 , A61K31/343 , A61K31/357 , A61K31/36 , A61K31/37 , A61K31/381 , A61K31/4025 , A61K31/404 , A61K31/41 , A61K31/415 , A61K31/4184 , A61K31/4192 , A61K31/423 , A61K31/428 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/443 , A61K31/444 , A61K31/453 , A61K31/47 , A61K31/4704 , A61K31/4709 , A61K31/472 , A61K31/496 , A61K31/4965 , A61K31/498 , A61K31/505 , A61K31/517 , A61K31/5375 , A61K31/538 , A61P1/00 , A61P1/04 , A61P1/12 , A61P3/10 , A61P9/00 , A61P11/00 , A61P11/02 , A61P11/06 , A61P13/00 , A61P13/10 , A61P17/00 , A61P17/02 , A61P17/04 , A61P17/06 , A61P17/14 , A61P19/02 , A61P25/00 , A61P25/06 , A61P27/02 , A61P29/00 , A61P31/12 , A61P37/08 , A61P43/00 , C07C233/11 , C07C233/15 , C07C233/33 , C07C233/44 , C07C311/13 , C07C311/16 , C07C317/40 , C07C323/35 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/64 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/22 , C07D215/227 , C07D215/32 , C07D215/38 , C07D215/40 , C07D215/42 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D235/08 , C07D235/26 , C07D237/20 , C07D239/42 , C07D239/88 , C07D239/90 , C07D241/20 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D311/16 , C07D319/18 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D215/16
CPC分类号： C07D471/04 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14
摘要： Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
-
公开(公告)号：US20050227986A1
公开(公告)日：2005-10-13
申请号：US11100077
申请日：2005-04-05
申请人： Yunxin Bo , Partha Chakrabarti , Ning Chen , Elizabeth Doherty , Christopher Fotsch , Nianhe Han , Michael Kelly , Qingyian Liu , Mark Norman , Vassil Ognyanov , Xianghong Wang , Jiawang Zhu
发明人： Yunxin Bo , Partha Chakrabarti , Ning Chen , Elizabeth Doherty , Christopher Fotsch , Nianhe Han , Michael Kelly , Qingyian Liu , Mark Norman , Vassil Ognyanov , Xianghong Wang , Jiawang Zhu
IPC分类号： C07D249/18 , A61K31/17 , A61K31/18 , A61K31/343 , A61K31/357 , A61K31/36 , A61K31/37 , A61K31/381 , A61K31/4025 , A61K31/404 , A61K31/41 , A61K31/415 , A61K31/4184 , A61K31/4192 , A61K31/423 , A61K31/428 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/443 , A61K31/444 , A61K31/453 , A61K31/47 , A61K31/4704 , A61K31/4709 , A61K31/472 , A61K31/496 , A61K31/4965 , A61K31/498 , A61K31/505 , A61K31/517 , A61K31/5375 , A61K31/538 , A61P1/00 , A61P1/04 , A61P1/12 , A61P3/10 , A61P9/00 , A61P11/00 , A61P11/02 , A61P11/06 , A61P13/00 , A61P13/10 , A61P17/00 , A61P17/02 , A61P17/04 , A61P17/06 , A61P17/14 , A61P19/02 , A61P25/00 , A61P25/06 , A61P27/02 , A61P29/00 , A61P31/12 , A61P37/08 , A61P43/00 , C07C233/11 , C07C233/15 , C07C233/33 , C07C233/44 , C07C311/13 , C07C311/16 , C07C317/40 , C07C323/35 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/64 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/22 , C07D215/227 , C07D215/32 , C07D215/38 , C07D215/40 , C07D215/42 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D235/08 , C07D235/26 , C07D237/20 , C07D239/42 , C07D239/88 , C07D239/90 , C07D241/20 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D311/16 , C07D319/18 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , A61K31/502 , C07D43/02
CPC分类号： C07D471/04 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14
摘要： Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
-
公开(公告)号：US20050277646A1
公开(公告)日：2005-12-15
申请号：US11195303
申请日：2005-08-01
申请人： Elizabeth Doherty , Jiawang Zhu , Markian Stec , Mark Norman , Vassil Ognyanov , Christopher Fotsch , Ning Chen , Partha Chakrabarti , Liping Pettus , Hui-Ling Wang , Xianghong Wang , Premilla Arasasingham
发明人： Elizabeth Doherty , Jiawang Zhu , Markian Stec , Mark Norman , Vassil Ognyanov , Christopher Fotsch , Ning Chen , Partha Chakrabarti , Liping Pettus , Hui-Ling Wang , Xianghong Wang , Premilla Arasasingham
IPC分类号： A61K31/4709 , A61K31/501 , A61K31/505 , A61K31/506 , A61K31/5377 , A61P1/00 , A61P1/04 , A61P9/00 , A61P11/00 , A61P11/02 , A61P11/06 , A61P13/00 , A61P15/00 , A61P17/00 , A61P17/02 , A61P17/06 , A61P17/14 , A61P19/02 , A61P25/00 , A61P25/02 , A61P25/04 , A61P25/06 , A61P27/02 , A61P29/00 , A61P37/08 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/64 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/22 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D43/02
CPC分类号： C07D231/40 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
摘要： Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
-
公开(公告)号：US20050277631A1
公开(公告)日：2005-12-15
申请号：US11195134
申请日：2005-08-01
申请人： Elizabeth Doherty , Jiawang Zhu , Markian Stec , Mark Norman , Hui-Ling Wang , Christopher Fotsch , Ning Chen , Partha Chakrabarti , Celia Dominguez , James Falsey , Christopher Hulme , Jodie Katon , Thomas Nixey , Vassil Ognyanov , Liping Pettus , Robert Rzasa
发明人： Elizabeth Doherty , Jiawang Zhu , Markian Stec , Mark Norman , Hui-Ling Wang , Christopher Fotsch , Ning Chen , Partha Chakrabarti , Celia Dominguez , James Falsey , Christopher Hulme , Jodie Katon , Thomas Nixey , Vassil Ognyanov , Liping Pettus , Robert Rzasa
IPC分类号： A61P29/00 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/64 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/22 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , A61K31/549 , A61K31/501 , C07D417/02 , C07D43/02
CPC分类号： C07D231/40 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/56 , C07D233/38 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12
摘要： Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
-
公开(公告)号：US20050272777A1
公开(公告)日：2005-12-08
申请号：US11195159
申请日：2005-08-01
申请人： Elizabeth Doherty , Jiawang Zhu , Markian Stec , Mark Norman , Hui-Ling Wang , Christopher Fotsch , Ning Chen , Partha Chakrabarti , Celia Dominguez , James Falsey , Christopher Hulme , Jodie Katon , Thomas Nixey , Vassil Ognyanov , Liping Pettus , Robert Rzasa
发明人： Elizabeth Doherty , Jiawang Zhu , Markian Stec , Mark Norman , Hui-Ling Wang , Christopher Fotsch , Ning Chen , Partha Chakrabarti , Celia Dominguez , James Falsey , Christopher Hulme , Jodie Katon , Thomas Nixey , Vassil Ognyanov , Liping Pettus , Robert Rzasa
IPC分类号： A61P29/00 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/64 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/22 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , A61K31/4439 , C07D417/02
CPC分类号： C07D231/40 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/56 , C07D233/38 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12
摘要： Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
-
公开(公告)号：US20090264424A1
公开(公告)日：2009-10-22
申请号：US12492376
申请日：2009-06-26
申请人： Yunxin Y. Bo , Partha P. Chakrabarti , Ning Chen , Elizabeth M. Doherty , Christopher H. Fotsch , Nianhe Han , Michael G. Kelly , Qingyian Liu , Mark Henry Norman , Vassil I. Ognyanov , Xianghong Wang , Jiawang Zhu
发明人： Yunxin Y. Bo , Partha P. Chakrabarti , Ning Chen , Elizabeth M. Doherty , Christopher H. Fotsch , Nianhe Han , Michael G. Kelly , Qingyian Liu , Mark Henry Norman , Vassil I. Ognyanov , Xianghong Wang , Jiawang Zhu
IPC分类号： A61K31/536 , C07D265/36 , A61P29/00
CPC分类号： C07D471/04 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14
摘要： Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
摘要翻译： 具有一般结构和含有它们的组合物的化合物，用于治疗急性，炎性和神经性疼痛，牙痛，一般头痛，偏头痛，丛集性头痛，混合血管和非血管综合征，紧张性头痛，一般炎症，关节炎，风湿性 疾病，骨关节炎，炎症性肠病，炎症性眼病，炎症性或不稳定性膀胱病，银屑病，皮肤炎症成分炎症，慢性炎性病症，炎性疼痛及相关的痛觉过敏和异常性疼痛，神经性疼痛及相关的痛觉过敏和异常性疼痛，糖尿病性神经病疼痛， 咳嗽痛，交感神经痛，交感综合征，哮喘，上皮组织损伤或功能障碍，单纯疱疹，呼吸道内脏运动紊乱，泌尿生殖道，胃肠道或血管区，伤口，烧伤，过敏性皮肤反应，瘙痒症，白癜风，一般胃肠道疾病， G 腹部溃疡，十二指肠溃疡，腹泻，坏死因子诱发的胃损伤，毛发生长，血管舒缩或过敏性鼻炎，支气管疾病或膀胱疾病。
-
公开(公告)号：US07579347B2
公开(公告)日：2009-08-25
申请号：US11100077
申请日：2005-04-05
申请人： Yunxin Y. Bo , Partha P. Chakrabarti , Ning Chen , Elizabeth M. Doherty , Christopher H. Fotsch , Nianhe Han , Michael G. Kelly , Qingyian Liu , Mark Henry Norman , Vassil I. Ognyanov , Xianghong Wang , Jiawang Zhu
发明人： Yunxin Y. Bo , Partha P. Chakrabarti , Ning Chen , Elizabeth M. Doherty , Christopher H. Fotsch , Nianhe Han , Michael G. Kelly , Qingyian Liu , Mark Henry Norman , Vassil I. Ognyanov , Xianghong Wang , Jiawang Zhu
IPC分类号： C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , A61K31/4427 , A61K31/4523 , A61K31/47 , A61K31/497 , A61K31/5377 , A61P29/00 , A61P25/04
CPC分类号： C07D471/04 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/40 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14
摘要： Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
摘要翻译： 具有一般结构和含有它们的组合物的化合物，用于治疗急性，炎性和神经性疼痛，牙痛，一般头痛，偏头痛，丛集性头痛，混合血管和非血管综合征，紧张性头痛，一般炎症，关节炎，风湿性 疾病，骨关节炎，炎症性肠病，炎症性眼病，炎症性或不稳定性膀胱病，银屑病，皮肤炎症成分炎症，慢性炎性病症，炎性疼痛及相关的痛觉过敏和异常性疼痛，神经性疼痛及相关的痛觉过敏和异常性疼痛，糖尿病性神经病疼痛， 咳嗽痛，交感神经痛，交感综合征，哮喘，上皮组织损伤或功能障碍，单纯疱疹，呼吸道内脏运动紊乱，泌尿生殖道，胃肠道或血管区，伤口，烧伤，过敏性皮肤反应，瘙痒症，白癜风，一般胃肠道疾病， G 腹部溃疡，十二指肠溃疡，腹泻，坏死因子诱发的胃损伤，毛发生长，血管舒缩或过敏性鼻炎，支气管疾病或膀胱疾病。
-
公开(公告)号：US20050014749A1
公开(公告)日：2005-01-20
申请号：US10874086
申请日：2004-06-21
申请人： Jian Chen , Ben Askew , Kaustav Biswas , Jennifer Chau , Derin D'Amico , Scott Harried , Thomas Nguyen , Wenyuan Qian , Jiawang Zhu , Christopher Fotsch , Aiwen Li , Qingyian Liu , Nobuku Nishimura , Tanya Peterkin , Babak Riahi , Chester Yuan , Nianhe Han , Rana Nomak , Kevin Yang
发明人： Jian Chen , Ben Askew , Kaustav Biswas , Jennifer Chau , Derin D'Amico , Scott Harried , Thomas Nguyen , Wenyuan Qian , Jiawang Zhu , Christopher Fotsch , Aiwen Li , Qingyian Liu , Nobuku Nishimura , Tanya Peterkin , Babak Riahi , Chester Yuan , Nianhe Han , Rana Nomak , Kevin Yang
IPC分类号： A61K31/495 , C07D241/00 , C07D241/08 , C07D243/08 , C07D245/02 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D279/12 , A61K31/537 , A61K31/54
CPC分类号： C07D241/08 , C07D243/08 , C07D245/02 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/14
摘要： Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
摘要翻译： 所选化合物对于治疗疼痛和疾病如炎症介导的疾病是有效的。 本发明包括新的化合物，类似物，前药和药学上可接受的衍生物，用于预防和治疗疾病和其它疾病或涉及疼痛，炎症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。
-
公开(公告)号：US20050234044A1
公开(公告)日：2005-10-20
申请号：US10823372
申请日：2004-04-13
申请人： Robert Groneberg , James Zhan , Benny Askew , Derin D'Amico , Nianhe Han , Christopher Fotsch , Qingyian Liu , Babak Riahi , Jiawang Zhu , Kevin Yang , Jian Chen , Rana Nomak
发明人： Robert Groneberg , James Zhan , Benny Askew , Derin D'Amico , Nianhe Han , Christopher Fotsch , Qingyian Liu , Babak Riahi , Jiawang Zhu , Kevin Yang , Jian Chen , Rana Nomak
IPC分类号： A61K31/425 , A61K31/4523 , A61K31/454 , A61K31/4545 , A61K31/4709 , A61K31/517 , A61K31/55 , A61P29/00 , C07D207/48 , C07D211/96 , C07D215/58 , C07D217/22 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/02 , C07D413/14 , C07D417/02 , C07D417/12 , C07D417/14 , C07D43/02
CPC分类号： C07D207/48 , C07D211/96 , C07D215/58 , C07D217/22 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
摘要翻译： 所选化合物对于治疗疼痛和疾病如炎症介导的疾病是有效的。 本发明包括新的化合物，类似物，前药和其药学上可接受的衍生物，用于预防和治疗疾病和其它疾病或涉及疼痛，炎症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。
-
-
-
-
-
-
-
-
-
搜索结果
35 条记录 (耗时 0.067 秒)
