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公开(公告)号：US09029389B2
公开(公告)日：2015-05-12
申请号：US14112933
申请日：2012-04-20
申请人： Zaesung No , Jaeseung Kim , Sung-Jun Han , Jung Hwan Kim , Young Sam Park , Sangchul Lee , Kiyean Nam , Jeongjun Kim , Jinhwa Lee , Sunhee Kang , Min Jung Seo , Saeyeon Lee , Gahee Choi
发明人： Zaesung No , Jaeseung Kim , Sung-Jun Han , Jung Hwan Kim , Young Sam Park , Sangchul Lee , Kiyean Nam , Jeongjun Kim , Jinhwa Lee , Sunhee Kang , Min Jung Seo , Saeyeon Lee , Gahee Choi
IPC分类号： A61K31/4353 , C07D491/113 , C07D471/04 , C07D487/04 , C07D519/00
CPC分类号： C07D491/113 , A61K31/4353 , C07D471/04 , C07D487/04 , C07D519/00
摘要： The present invention refers to: a compound having the general formula (I), wherein n is 0, 1, 2 or; m is 0, 1, 2 or 3; o is 0, 1, 2 or 3; W, X, Y and Z are independently selected from CH, N or N-oxide; A is NR4, C═O, C═S, OP(O)(O), P═O, CH2, or a heteroarly selected from the group consisting of (a), (b), (c), (d), (e), (f), (g); V is C═O, O, S, CH2, or NR5; as well as its use in treating inflammatory diseases such as asthma, COPD, inflammation post infection, arthritis, atherosclerosis, pain and dermatitis.
摘要翻译： 本发明涉及：具有通式（I）的化合物，其中n为0,1,2或; m为0,1,2或3; o为0,1,2或3; W，X，Y和Z独立地选自CH，N或N-氧化物; A是NR4，C = O，C≡S，OP（O）（O），P = O，CH2或杂原子选自（a），（b），（c），（d） ，（e），（f），（g）; V是C = O，O，S，CH 2或NR 5; 以及其用于治疗炎性疾病如哮喘，COPD，炎症后感染，关节炎，动脉粥样硬化，疼痛和皮炎的用途。
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公开(公告)号：US20140155387A1
公开(公告)日：2014-06-05
申请号：US14112933
申请日：2012-04-20
申请人： Zaesung No , Jaeseung Kim , Sung-Jun Han , Jung Hwan Kim , Young Sam Park , Sangchul Lee , Kiyean Nam , Jeongjun Kim , Jinhwa Lee , Sunhee Kang , Min Jung Seo , Saeyeon Lee , Gahee Choi
发明人： Zaesung No , Jaeseung Kim , Sung-Jun Han , Jung Hwan Kim , Young Sam Park , Sangchul Lee , Kiyean Nam , Jeongjun Kim , Jinhwa Lee , Sunhee Kang , Min Jung Seo , Saeyeon Lee , Gahee Choi
IPC分类号： C07D491/113 , C07D487/04 , C07D471/04
CPC分类号： C07D491/113 , A61K31/4353 , C07D471/04 , C07D487/04 , C07D519/00
摘要： The present invention refers to: a compound having the general formula (I), wherein n is 0, 1, 2 or; m is 0, 1, 2 or 3; o is 0, 1, 2 or 3; W, X, Y and Z are independently selected from CH, N or N-oxide; A is NR4, C═O, C═S, OP(O)(O), P═O, CH2, or a heteroarly selected from the group consisting of (a), (b), (c), (d), (e), (f), (g); V is C═O, O, S, CH2, or NR5; as well as its use in treating inflammatory diseases such as asthma, COPD, inflammation post infection, arthritis, atherosclerosis, pain and dermatitis.
摘要翻译： 本发明涉及：具有通式（I）的化合物，其中n为0,1,2或; m为0,1,2或3; o为0,1,2或3; W，X，Y和Z独立地选自CH，N或N-氧化物; A是NR4，C = O，C≡S，OP（O）（O），P = O，CH2或杂原子选自（a），（b），（c），（d） ，（e），（f），（g）; V是C = O，O，S，CH 2或NR 5; 以及其用于治疗炎性疾病如哮喘，COPD，炎症后感染，关节炎，动脉粥样硬化，疼痛和皮炎的用途。
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公开(公告)号：US20130012506A1
公开(公告)日：2013-01-10
申请号：US13518292
申请日：2011-01-13
申请人： Zaesung No , Jaeseung Kim , Priscille Brodin , Min Jung Seo , Eunjung Park , Jonathan Cechetto , Heekyoung Jeon , EunHye Kim , Jamung Heo , Ji Youn Nam , Denis Philippe Cedric Fenistein , Thierry Christophe , Monica Contreras Dominguez , Auguste Genovesio , Saeyeon Lee , Sunhee Kang , Fanny Anne Ewann
发明人： Zaesung No , Jaeseung Kim , Priscille Brodin , Min Jung Seo , Eunjung Park , Jonathan Cechetto , Heekyoung Jeon , EunHye Kim , Jamung Heo , Ji Youn Nam , Denis Philippe Cedric Fenistein , Thierry Christophe , Monica Contreras Dominguez , Auguste Genovesio , Saeyeon Lee , Sunhee Kang , Fanny Anne Ewann
IPC分类号： C07D239/70 , A61P31/06 , A61K31/5377 , A61P31/04 , A61K31/519 , C07D413/14
CPC分类号： C07D471/14 , C07D471/04
摘要： The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.
摘要翻译： 本发明涉及小分子化合物及其在治疗细菌感染，特别是结核病中的用途。
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公开(公告)号：US20110178077A1
公开(公告)日：2011-07-21
申请号：US12999095
申请日：2009-06-17
申请人： Priscille Brodin , Thierry Christophe , Zaesung No , Jaeseung Kim , Auguste Genovesio , Denis Philippe Cedric Fenistein , Heekyoung Jeon , Fanny Anne Ewann , Sunhee Kang , Saeyeon Lee , Min Jung Seo , Eunjung Park , Monica Contreras Dominguez , Ji Youn Nam , Eun Hye Kim
发明人： Priscille Brodin , Thierry Christophe , Zaesung No , Jaeseung Kim , Auguste Genovesio , Denis Philippe Cedric Fenistein , Heekyoung Jeon , Fanny Anne Ewann , Sunhee Kang , Saeyeon Lee , Min Jung Seo , Eunjung Park , Monica Contreras Dominguez , Ji Youn Nam , Eun Hye Kim
IPC分类号： A61K31/5377 , C07D471/04 , C07C233/73 , C07C233/78 , C07C205/61 , C07D207/12 , C07D211/46 , C07D241/04 , C07D401/12 , A61K31/519 , A61K31/166 , A61K31/24 , A61K31/402 , A61K31/45 , A61K31/495 , A61P31/04 , A61P31/06
CPC分类号： C12Q1/18 , C07C255/66 , C07C335/40 , C07D223/24 , C07D233/84 , C07D251/52 , C07D251/66 , C07D271/113 , C07D401/12 , C07D409/12 , C07D417/12 , C07D471/04 , C07D498/04
摘要： The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.
摘要翻译： 本发明涉及小分子化合物及其在治疗细菌感染，特别是结核病中的用途。
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公开(公告)号：US20130065884A1
公开(公告)日：2013-03-14
申请号：US13634165
申请日：2011-03-18
申请人： Zaesung No , Jaeseung Kim , Priscille Brodin , Min Jung Seo , Young Mi Kim , Jonathan Cechetto , Heekyoung Jeon , Auguste Genovesio , Saeyeon Lee , Sunhee Kang , Fanny Anne Ewann , Ji Youn Nam , Thierry Christophe , Denis Philippe Cedric Fenistein , Heo Jamung , Jang Jiyeon
发明人： Zaesung No , Jaeseung Kim , Priscille Brodin , Min Jung Seo , Young Mi Kim , Jonathan Cechetto , Heekyoung Jeon , Auguste Genovesio , Saeyeon Lee , Sunhee Kang , Fanny Anne Ewann , Ji Youn Nam , Thierry Christophe , Denis Philippe Cedric Fenistein , Heo Jamung , Jang Jiyeon
IPC分类号： A61K31/437 , A61K31/444 , A61K31/4545 , A61K31/5377 , A61P31/06 , C07D487/04 , A61K31/4985 , A61K31/55 , A61K31/4725 , A61P31/04 , C07D471/04 , A61K31/496
CPC分类号： C07D401/04 , A61K31/437 , C07D471/04 , C07D487/04
摘要： The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.
摘要翻译： 本发明涉及小分子化合物及其在治疗细菌感染，特别是结核病中的用途。
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公开(公告)号：US08865734B2
公开(公告)日：2014-10-21
申请号：US13634165
申请日：2011-03-18
申请人： Zaesung No , Jaeseung Kim , Priscille Brodin , Min Jung Seo , Young Mi Kim , Jonathan Cechetto , Heekyoung Jeon , Auguste Genovesio , Saeyeon Lee , Sunhee Kang , Fanny Anne Ewann , Ji Youn Nam , Thierry Christophe , Denis Philippe Cedric Fenistein , Jamung Heo , Jang Jiyeon
发明人： Zaesung No , Jaeseung Kim , Priscille Brodin , Min Jung Seo , Young Mi Kim , Jonathan Cechetto , Heekyoung Jeon , Auguste Genovesio , Saeyeon Lee , Sunhee Kang , Fanny Anne Ewann , Ji Youn Nam , Thierry Christophe , Denis Philippe Cedric Fenistein , Jamung Heo , Jang Jiyeon
IPC分类号： C07D401/04 , A61K31/437
CPC分类号： C07D401/04 , A61K31/437 , C07D471/04 , C07D487/04
摘要： The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.
摘要翻译： 本发明涉及小分子化合物及其在治疗细菌感染，特别是结核病中的用途。
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公开(公告)号：US08785452B2
公开(公告)日：2014-07-22
申请号：US12999095
申请日：2009-06-17
申请人： Priscille Brodin , Thierry Christophe , Zaesung No , Jaeseung Kim , Auguste Genovesio , Denis Philippe Cedric Fenistein , Heekyoung Jeon , Fanny Anne Ewann , Sunhee Kang , Saeyeon Lee , Min Jung Seo , Eunjung Park , Monica Contreras Dominguez , Ji Youn Nam , Eun Hye Kim
发明人： Priscille Brodin , Thierry Christophe , Zaesung No , Jaeseung Kim , Auguste Genovesio , Denis Philippe Cedric Fenistein , Heekyoung Jeon , Fanny Anne Ewann , Sunhee Kang , Saeyeon Lee , Min Jung Seo , Eunjung Park , Monica Contreras Dominguez , Ji Youn Nam , Eun Hye Kim
IPC分类号： A01N43/90 , A61K31/519 , C07D239/70 , C07D471/04
CPC分类号： C12Q1/18 , C07C255/66 , C07C335/40 , C07D223/24 , C07D233/84 , C07D251/52 , C07D251/66 , C07D271/113 , C07D401/12 , C07D409/12 , C07D417/12 , C07D471/04 , C07D498/04
摘要： The present invention relates to 4H-pyrido[1,2-a]pyrimidin-4-one compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.
摘要翻译： 本发明涉及4H-吡啶并[1,2-a]嘧啶-4-酮化合物及其在治疗细菌感染，特别是结核病中的用途。
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公开(公告)号：US20130227150A1
公开(公告)日：2013-08-29
申请号：US13806569
申请日：2011-06-22
申请人： Junho Ahn , Yanghwan Kim , Hoonbong Lee , Koonseok Lee , Sunhee Kang , Seonghwan Kang , Yongtae Kwon , Jaekuk Kwon , Hoyoung Kim , Hyoungjun Park , Jimoom Jung , Younghoon Joo
发明人： Junho Ahn , Yanghwan Kim , Hoonbong Lee , Koonseok Lee , Sunhee Kang , Seonghwan Kang , Yongtae Kwon , Jaekuk Kwon , Hoyoung Kim , Hyoungjun Park , Jimoom Jung , Younghoon Joo
IPC分类号： H04L29/06
CPC分类号： H04L65/1069 , H02J13/0079 , H02J2003/143 , H04L12/12 , H04L12/2807 , Y02B70/3216 , Y02B70/325 , Y02B70/3266 , Y02B90/2669 , Y02D50/20 , Y02D50/40 , Y04S20/221 , Y04S20/228 , Y04S20/242 , Y04S40/128
摘要： Provided is a network system. The network system includes a first component performing a preset function, the first component having a first device code and a second component exchanging information with the first component to be communicably connected to the first component, the second component having a second device code. When a command for communicable connection is inputted into the first component or the second component, a connection sequence is generated from the component in which the command is inputted to exchange an IP address and the device code of each of the components between one component generating the connection sequence and the other component receiving the connection sequence.
摘要翻译： 提供了一个网络系统。 网络系统包括执行预设功能的第一组件，第一组件具有第一设备代码，第二组件与第一组件交换信息以与第一组件可通信地连接，第二组件具有第二设备代码。 当用于可通信连接的命令被输入到第一组件或第二组件中时，从输入命令的组件生成连接序列，以交换IP地址，并且在一个组件之间产生每个组件的设备代码 连接序列，另一个组件接收连接序列。
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9.发明申请3-aryl--3-methyl-quinoline-2, 4-diones, preparation method thereof, and pharmaceutical composition containing the same 失效3-芳基-3-甲基 - 喹啉-2,4-二酮及其制备方法和含有它们的药物组合物公开(公告)号：US20060084676A1
公开(公告)日：2006-04-20
申请号：US11242665
申请日：2005-10-04
申请人： Churlmin Seong , Nosang Park , Yungsik Jung , Jinil Choi , Wookyu Park , Heeyung Cho , Jaeyang Kong , Daeyoung Jung , Sunhee Kang , Sukjin Song , Kyungran Kwark
发明人： Churlmin Seong , Nosang Park , Yungsik Jung , Jinil Choi , Wookyu Park , Heeyung Cho , Jaeyang Kong , Daeyoung Jung , Sunhee Kang , Sukjin Song , Kyungran Kwark
IPC分类号： A61K31/4704 , C07D215/36
CPC分类号： C07C233/55 , C07C235/38 , C07C237/20 , C07C271/44 , C07C275/42 , C07D215/22
摘要： The present invention relates to compounds of 3-aryl-3-methyl-quinoline-2,4-diones acting as a 5HT6 receptor antagonist, a preparation method thereof, and a pharmaceutical composition containing the same for treatment of the central nervous system disorders. The compounds of 3-aryl-3-methyl-quinoline-2,4-diones according to the present invention may be valuably used for treatment of a 5HT6 receptor relating disorders because of its excellent binding affinity for the 5HT6 receptor and excellent selectivity for the 5HT6 receptor over other receptors.
摘要翻译： 本发明涉及作为5HT6受体拮抗剂的3-芳基-3-甲基 - 喹啉-2,4-二酮的化合物，其制备方法和含有该化合物的药物组合物，用于治疗中枢神经系统疾病。 根据本发明的3-芳基-3-甲基 - 喹啉-2,4-二酮的化合物可以有价值地用于治疗5HT6受体相关疾病，因为其对5HT6受体具有优异的结合亲和力，并且对于 5HT6受体超过其他受体。
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公开(公告)号：US09836803B2
公开(公告)日：2017-12-05
申请号：US13806924
申请日：2011-06-24
申请人： Junho Ahn , Yanghwan Kim , Hoonbong Lee , Koonseok Lee , Sangseog Kang , Sunhee Kang , Younghyun Kang , Youngtae Kwon , Jaekuk Kwon , Byeongho Min , Kicheol Shin , Dongchun Shin , Taeyun Lim , Shinjae Jeong , Kyungeun Jo , Juyoung Cha , Sungyong Heo
发明人： Junho Ahn , Yanghwan Kim , Hoonbong Lee , Koonseok Lee , Sangseog Kang , Sunhee Kang , Younghyun Kang , Youngtae Kwon , Jaekuk Kwon , Byeongho Min , Kicheol Shin , Dongchun Shin , Taeyun Lim , Shinjae Jeong , Kyungeun Jo , Juyoung Cha , Sungyong Heo
CPC分类号： G06Q50/06 , H02J3/14 , H02J13/0055 , H02J2003/143 , H02J2003/146 , H04L12/12 , H04L12/2803 , Y02B70/3225 , Y02B70/325 , Y02B70/3266 , Y02D50/20 , Y02D50/40 , Y04S20/222 , Y04S20/224 , Y04S20/228 , Y04S20/242
摘要： A network system is provided. The network system includes: at least one component selected from an energy receiving unit receiving energy and an energy management unit managing the energy receiving unit. The energy receiving unit or the energy management unit receives energy rate related information; an energy usage amount or a usage rate of when the component is controlled on the basis of at least the energy rate related information is less than that of when the component is controlled without the basis of at least energy rate related information; if the energy rate related information is high cost information, a function of one component constituting the energy receiving unit is limited; and an operating time or an output of the energy receiving unit is adjusted in correspondence to the limited function of one component.
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