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1.发明公开公开(公告)号：US20240317826A1
公开(公告)日：2024-09-26
申请号：US18290059
申请日：2022-05-11
CPC分类号： C07K14/4702 , A61K45/06 , A61P31/18 , A61K38/00 , C07K2319/21 , C07K2319/23
摘要： The present invention relates, in part, to compositions and methods for treating and/or identifying an agent for treating HIV infections.
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公开(公告)号：US20240161421A1
公开(公告)日：2024-05-16
申请号：US18210435
申请日：2023-06-15
申请人： MONTEFIORE MEDICAL CENTER , ALBERT EINSTEIN COLLEGE OF MEDICINE , The New York City Health and Hospitals Corporation
IPC分类号： G06T19/00 , A61B5/00 , A61B34/10 , A61B90/00 , G06T7/00 , G06T7/62 , G06T7/68 , G06T7/73 , G06T19/20 , G16H50/50
CPC分类号： G06T19/006 , A61B5/0077 , A61B34/10 , A61B90/36 , A61B90/361 , G06T7/0014 , G06T7/62 , G06T7/68 , G06T7/74 , G06T19/20 , G16H50/50 , A61B2034/105 , A61B2034/2055 , A61B2090/366 , A61B2090/368
摘要： Methods and devices are disclosed for intra-operative viewing of pre- and intra-operative 3D patient images.
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公开(公告)号：US20240156720A1
公开(公告)日：2024-05-16
申请号：US18419852
申请日：2024-01-23
发明人： Joel M. Friedman
IPC分类号： A61K9/00 , A61K9/06 , A61K31/05 , A61K31/12 , A61K31/121 , A61K31/352 , A61K31/366 , A61K31/4375 , A61K31/593 , A61K47/10 , A61K47/12 , A61P7/00 , A61P37/06
CPC分类号： A61K9/0014 , A61K9/06 , A61K31/05 , A61K31/12 , A61K31/121 , A61K31/352 , A61K31/366 , A61K31/4375 , A61K31/593 , A61K47/10 , A61K47/12 , A61P7/00 , A61P37/06
摘要： Formulations comprising one or more active agents for blood storage and transfusions are provided. Also provided methods for prolonging viability of blood and enhancing efficacy of blood transfusion.
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公开(公告)号：US20240101650A1
公开(公告)日：2024-03-28
申请号：US18256556
申请日：2021-12-15
发明人： Jacqueline M. Achkar , Elise Ishida , Yanyan Liu , Tingting Chen
IPC分类号： C07K16/12 , A61P31/06 , G01N33/543 , G01N33/569
CPC分类号： C07K16/1289 , A61P31/06 , G01N33/54386 , G01N33/5695 , C07K2317/21 , C07K2317/77 , C07K2317/92 , G01N2333/35
摘要： Provided are high affinity Mycobacterium tuberculosis arabinomannan-specific antibodies and antigen-binding fragments thereof. Also provided are methods of use and devices employing such Mycobacterium tuberculosis arabinomannan-specific antibodies and antigen-binding fragments thereof.
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公开(公告)号：US11938128B2
公开(公告)日：2024-03-26
申请号：US16492300
申请日：2018-03-09
发明人： Evripidis Gavathiotis , Richard N. Kitsis , Thomas P. Garner , Dulguun Amgalan , Lorrie Kirshenbaum , Felix Kopp
IPC分类号： A61K31/496 , A61K31/495 , C07D209/86 , C07D209/88 , C07D279/26 , C07D295/13
CPC分类号： A61K31/496 , A61K31/495 , C07D209/86 , C07D209/88 , C07D279/26 , C07D295/13
摘要： Compounds, compositions and method of using these compounds are disclosed for treating a disease or disorder in which it is desirable to inhibit BAX, such as a cardiovascular disease or disorder.
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公开(公告)号：US20240033490A1
公开(公告)日：2024-02-01
申请号：US18487659
申请日：2023-10-16
发明人： Joel M. Friedman
CPC分类号： A61M31/00 , A61M35/30 , A61M2202/0275
摘要： A device for generating nitric oxide is disclosed. The device is configured for applying to either a body cavity or a surface of a subject in need thereof. Also disclosed is a method for the treatment of diseases or conditions with the device.
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公开(公告)号：US20240033301A1
公开(公告)日：2024-02-01
申请号：US18487635
申请日：2023-10-16
发明人： Joel M. Friedman
IPC分类号： A61K35/644 , A61P31/06 , A61K47/10
CPC分类号： A61K35/644 , A61P31/06 , A61K47/10
摘要： A composition and a kit comprising a nitrite source admixed with a gelling agent for nitric oxide production. Also disclosed is a method for generating nitric oxide, which finds applications in the treatment of various diseases.
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公开(公告)号：US20240000391A1
公开(公告)日：2024-01-04
申请号：US18339020
申请日：2023-06-21
CPC分类号： A61B5/704 , A61B5/0068 , A61B5/0071 , A61B5/08 , A61B5/418 , A61B5/4222 , A61B5/4872 , G02B21/367 , A61B2503/42
摘要： Methods and apparatus are provided for high resolution intravital imaging and for chronic optical imaging of tissues such as lung.
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9.发明公开公开(公告)号：US20230392182A1
公开(公告)日：2023-12-07
申请号：US18250685
申请日：2021-11-01
CPC分类号： C12Q1/04 , C12N15/62 , C12N15/86 , C12N9/0069 , C12Q1/18 , C12R2001/32
摘要： A reporter mycobacteriophage comprising a heterologous nucleic acid comprising a promoter-reporter construct encoding a promotor operably linked to a nucleotide sequence encoding a fusion protein, wherein the fusion protein comprises a luciferase protein linked to a fluorescent protein. Methods of utilizing the reporter mycobacteriophage in detection of a viable target microbe in a sample, screening a test substance for treatment of tuberculosis, and detecting a drug-resistant Mycobacterium in a subject are provided.
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公开(公告)号：US11802875B2
公开(公告)日：2023-10-31
申请号：US16616848
申请日：2018-05-30
发明人： John S. Condeelis , Maja Oktay
IPC分类号： G01N33/574 , A61K31/337 , A61K45/06
CPC分类号： G01N33/57415 , A61K31/337 , A61K45/06 , G01N33/5748
摘要： Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using Tie-2 inhibitors. Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using inhibitors of Mena expression and/or function are also provided.
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