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公开(公告)号：US12226561B2
公开(公告)日：2025-02-18
申请号：US17671353
申请日：2022-02-14
Applicant: Life Technologies Corporation , Life Technologies AS
Inventor： Lars Norderhaug , Angel Varela-Rohena , Nephi D. Jones
IPC: A61M1/36 , B01L3/00 , B03C1/01 , B03C1/28 , B03C1/30 , C07K16/28 , C12M1/00 , C12M1/12 , C12M1/26 , C12M3/00
Abstract: A magnetic particle separation system includes a magnetic field generating device having an upper surface with a receiving area formed thereon; and a magnetic field generating element disposed beneath the upper surface, the magnetic field generating element being configured to produce a magnetic field above the upper surface. A container assembly is disposed on the upper surface and includes: a flexible container having an outer wall with an interior surface that at least partially bounds an internal compartment, the outer wall having a front side and an opposing back side with the internal compartment disposed therebetween; a fluid inlet extending through the outer wall at the front side; a fluid outlet extending through the outer wall at the front side; and a first partition projecting into the internal compartment from the front side between the fluid inlet and the fluid outlet.
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公开(公告)号：US20240392226A1
公开(公告)日：2024-11-28
申请号：US18248428
申请日：2021-10-12
Applicant: LIFE TECHNOLOGIES AS , LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES HOLDINGS PTE LIMITED
Inventor： Morten LUHR , Michael GORDON , Ming Tiong SIA , Kok Shyong CHONG , Woon Liang Terence SOH , Seng Leong LIM , Ida Caroline SCHROEDER , Katrine ALFSNES , Terry JianHui LIM , Marie BOSNES , Axl Alois NEURAUTER , Ketil Winther PEDERSEN , Autumn Day WILBUR , Sean ZIMMERMAN
Abstract: A bead processing assembly for use in attaching magnetic beads to biological cells and other biological materials and/or separating magnetic beads from biological cells and other biological materials includes a base assembly having a housing, a support panel disposed on the housing and having a front face, a first pinch valve at least partially outwardly projecting from the front face of the support panel, and a first pump at least partially outwardly projecting from the front face of the support panel. A rocker assembly is supported on the base assembly and includes a mount assembly supported on the base assembly, a platform assembly pivotably secured to the mount assembly, and a rocker drive for repeatedly rocking the platform assembly relative to the mount assembly.
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公开(公告)号：US20230167210A1
公开(公告)日：2023-06-01
申请号：US18101785
申请日：2023-01-26
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir FONNUM , Grete Irene MODAHL , Nini Hofsloekken KJUS , Astrid Evenroed MOLTEBERG , Diem Thuy Thi TRAN , Jo AASERUD , M. Talha GOKMEN , Steven M. MENCHEN , Carl FULLER , Luisa ANDRUZZI , Wolfgang HINZ
IPC: C08F130/08 , C07F7/18 , C08F8/12 , C12Q1/686 , C08F2/20 , C08F2/26 , C08F230/08 , C08F6/24 , C08F222/38 , C08F8/32 , C08F8/34 , C12P19/34 , C12Q1/6874 , G01N27/414 , C08J9/20
CPC classification number: C08F130/08 , C07F7/1804 , C08F8/12 , C12Q1/686 , C07F7/188 , C08F2/20 , C08F2/26 , C08F230/085 , C08F6/24 , C08F222/385 , C08F8/32 , C08F8/34 , C12P19/34 , C12Q1/6874 , G01N27/4145 , C08J9/20 , Y10T428/2982 , C08F2800/20 , C08F220/603
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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公开(公告)号：US20220275331A1
公开(公告)日：2022-09-01
申请号：US17578172
申请日：2022-01-18
Applicant: LIFE TECHNOLOGIES AS
Inventor： Hilde ALMAASBAK , Tanja AARVAK , Kerstin BERNSTROEM , Oystein AAMELLEM
IPC: C12N5/0783
Abstract: This invention relates, inter alia, to compositions of expanded T cell populations, methods for the expansion of T cell populations and methods for using such populations of cells. In some aspects, the invention relates to compositions and methods for the selective expansion of T cell subpopulations present in mixed T cell populations, as well as T cell subpopulations produced by methods for the invention.
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公开(公告)号：US20190264017A1
公开(公告)日：2019-08-29
申请号：US16305372
申请日：2017-06-07
Inventor： Kristian ANDERSSON , Geir FONNUM , Korbinian HEIL
IPC: C08L25/14 , C08F212/08 , B01J19/00
Abstract: This invention relates to polymer particles for solid phase oligonucleotide synthesis. The oligonucleotide may be linked to the particle via a linker having an amide-oligoethyleneglycol-amine structure. The particles may be considered to act as a solid support during the oligonucleotide synthesis. Also disclosed are processes for preparing such polymer particles, compositions and systems comprising such particles, and uses thereof.
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Patent Agency Ranking
公开(公告)号：US10246533B2
公开(公告)日：2019-04-02
申请号：US14970192
申请日：2015-12-15
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir Fonnum , Grete Irene Modahl , Nini Hofslokken Kjus , Astrid Evenroed Molteberg , Diem Tran , Jo Aaserud , M. Talha Gokmen , Steven M. Menchen , Carl Fuller , Luisa Andruzzi , Wolfgang Hinz
IPC: C08F130/08 , C08F6/24 , C07F7/18 , C08F2/20 , C08F2/26 , C08F220/58 , C08F230/08 , C08F222/38 , C08F8/32 , C08F8/34 , C12Q1/686 , C12P19/34 , C12Q1/6874 , G01N27/414 , C08J9/20 , C08F8/12
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of monomer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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公开(公告)号：US09868826B2
公开(公告)日：2018-01-16
申请号：US15200533
申请日：2016-07-01
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir Fonnum , Steven M. Menchen , Talha M. Gokmen , Pontus Lundberg , Prasanna Krishnan Thwar , Alfred Lui , Lily Lu , Wolfgang Hinz , Lene Husaboe , Elisabeth Breivold , Astrid Evenroed Molteberg , Synne Larsen
IPC: C08J3/075 , C08F220/58 , C08F8/12 , C08F220/70 , C08F230/08
CPC classification number: C08J3/075 , C08F8/12 , C08F220/58 , C08F220/70 , C08F2230/085 , C08J2333/26 , C08F222/38
Abstract: A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.
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公开(公告)号：US20140179025A1
公开(公告)日：2014-06-26
申请号：US14190054
申请日：2014-02-25
Applicant: LIFE TECHNOLOGIES AS
Inventor： Ellen Weng , Geir Fonnum , Grete Modahl , Astrid Molteberg , Erling Finne
IPC: G01N33/543
CPC classification number: C09K11/06 , B82Y25/00 , B82Y40/00 , C08F220/18 , C09K11/025 , G01N33/5434 , H01F1/0018 , H01F1/01 , H01F1/26 , H01F41/00 , Y10T428/2991 , Y10T428/2998
Abstract: A coated magnetic particle comprising an optionally porous magnetic polymer particle of a matrix polymer, said polymer particle having on a surface and/or in the pores thereof superparamagnetic crystals, said coated particle having a coat formed of a coating polymer, wherein said coated magnetic particle is essentially non-autofluorescent.
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公开(公告)号：US08722429B2
公开(公告)日：2014-05-13
申请号：US12486590
申请日：2009-06-17
Applicant: Ellen Weng , Geir Fonnum , Grete Irene Modahl , Astrid Evenrød Molteberg , Erling Sigurd Finne , Torkel Stene
Inventor： Ellen Weng , Geir Fonnum , Grete Irene Modahl , Astrid Evenrød Molteberg , Erling Sigurd Finne , Torkel Stene
IPC: G01N33/553
CPC classification number: C09K11/06 , B82Y25/00 , B82Y40/00 , C08F220/18 , C09K11/025 , G01N33/5434 , H01F1/0018 , H01F1/01 , H01F1/26 , H01F41/00 , Y10T428/2991 , Y10T428/2998
Abstract: A coated magnetic particle comprising an optionally porous magnetic polymer particle of a matrix polymer, said polymer particle having on a surface and/or in the pores thereof superparamagnetic crystals, said coated particle having a coat formed of a coating polymer, wherein said coated magnetic particle is essentially non-autofluorescent.
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公开(公告)号：US08697453B2
公开(公告)日：2014-04-15
申请号：US13651120
申请日：2012-10-12
Applicant: Life Technologies Corporation
Inventor： Ellen Weng , Geir Fonnum , Grete Modahl , Astrid Molteberg , Erling Finne
IPC: G01N33/553 , G01N33/544 , B32B5/16 , A61K49/10
CPC classification number: C09K11/06 , B82Y25/00 , B82Y40/00 , C08F220/18 , C09K11/025 , G01N33/5434 , H01F1/0018 , H01F1/01 , H01F1/26 , H01F41/00 , Y10T428/2991 , Y10T428/2998
Abstract: A coated magnetic particle comprising an optionally porous magnetic polymer particle of a matrix polymer, said polymer particle having on a surface and/or in the pores thereof superparamagnetic crystals, said coated particle having a coat formed of a coating polymer, wherein said coated magnetic particle is essentially non-autofluorescent.
Abstract translation: 一种涂覆的磁性颗粒，其包含基质聚合物的任选多孔磁性聚合物颗粒，所述聚合物颗粒在表面上和/或其孔中具有超顺磁性晶体，所述涂覆颗粒具有由涂覆聚合物形成的涂层，其中所述涂覆的磁性颗粒 本质上是非自发荧光。
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