公开(公告)号：US20240279261A1

公开(公告)日：2024-08-22

申请号：US18651633

申请日：2024-04-30

申请人： ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.

发明人： Xinfeng HAN ,  Dongxu LI ,  Mingqian YANG ,  Chengjun LIAO ,  Shufang QIN ,  Jiaxing LUO

IPC分类号： C07H3/02 ,  B01D1/28 ,  B01D9/00 ,  B01D15/36 ,  B01D21/26 ,  B01D69/02 ,  B01F21/00 ,  B01F35/21 ,  C07H1/06

CPC分类号： C07H3/02 ,  B01D1/28 ,  B01D9/0022 ,  B01D9/0031 ,  B01D15/361 ,  B01D21/262 ,  B01D69/02 ,  B01F21/00 ,  B01F35/2115 ,  C07H1/06 ,  B01D2009/0086 ,  B01D2325/02834

摘要： Embodiments of the present disclosure provide a method for preparing a high-purity arabinose crystal, comprising operations of dissolving, blending, ion exchange, decolorization and filtration, fine filtration, evaporation and concentration, crystallization, centrifugation, and drying performed in sequence on a low-purity arabinose crystal. Throughout the operations of preparing the arabinose crystal, a pH value of a material may be controlled between 4.3 and 7.5, and a temperature may not exceed 70° C. This prevents arabinose from transforming into impurities under a high temperature, thereby maintaining and improving a purity of the prepared arabinose crystal.

公开(公告)号：US11732287B2

公开(公告)日：2023-08-22

申请号：US15940850

申请日：2018-03-29

申请人： The Regents of the University of California

发明人： Adam R. Abate ,  John R. Haliburton ,  Freeman Lan ,  Adam R. Sciambi

IPC分类号： C12Q1/6804 ,  C12Q1/6806 ,  C12N15/10 ,  C12Q1/68 ,  B01L3/00 ,  B01F25/433 ,  B01F33/302 ,  C12Q1/6874 ,  B01L7/00 ,  B01F21/00

CPC分类号： C12Q1/6804 ,  B01F25/4338 ,  B01F33/3021 ,  B01L3/502784 ,  C12N15/1096 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/6874 ,  B01F21/00 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/502761 ,  B01L7/52 ,  B01L2200/0647 ,  B01L2200/0652 ,  B01L2300/021 ,  B01L2300/0645 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/123 ,  B01L2400/043 ,  B01L2400/0409 ,  B01L2400/0415 ,  B01L2400/0424 ,  C12N15/1096 ,  C12Q2535/122 ,  C12Q2563/159 ,  C12Q2563/179 ,  C12Q1/6806 ,  C12Q2535/122 ,  C12Q2563/159 ,  C12Q2563/179

摘要： Microfluidic methods for barcoding nucleic acid target molecules to be analyzed, e.g., via nucleic acid sequencing techniques, are provided. Also provided are microfluidic, droplet-based methods of preparing nucleic acid barcodes for use in various barcoding applications. The methods described herein facilitate high-throughput sequencing of nucleic acid target molecules as well as single cell and single virus genomic, transcriptomic, and/or proteomic analysis/profiling. Systems and devices for practicing the subject methods are also provided.