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1.发明申请公开(公告)号：US20130084252A1
公开(公告)日：2013-04-04
申请号：US13616134
申请日：2012-09-14
申请人： Michael Backes , Tobias Vössing , Jakob Peter Ley , Susanne Paetz
发明人： Michael Backes , Tobias Vössing , Jakob Peter Ley , Susanne Paetz
CPC分类号： A23L1/2363 , A23L27/204 , A23L27/2052 , A23L27/88 , A61K8/498 , A61K47/22 , A61K2800/10 , A61Q19/00 , C07C57/52 , C07C57/60 , C07C57/64 , C07D311/20
摘要： The present invention primarily relates to the use of one or a plurality of neoflavonoids of formula (I) and/or one or a plurality of physiologically acceptable salts of one or a plurality of neoflavonoids of formula (I) for producing a sensory impression of sweetness (i.e. an impression of sweetness) in an orally consumable preparation or for intensifying the sensory impression of sweetness of an orally consumable preparation comprising at least one further sweet-tasting and/or sweet-smelling substance. The present invention further relates to certain semifinished products and certain orally consumable preparations containing one or a plurality of neoflavonoids of formula (I) and/or one or a plurality of physiologically acceptable salts of one or a plurality of neoflavonoids of formula (I). Finally the invention also relates to a method of producing an orally consumable preparation and a method of producing and/or intensifying a sensory impression of sweetness in/of an orally consumable preparation.
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公开(公告)号：US09963481B2
公开(公告)日：2018-05-08
申请号：US14343426
申请日：2012-09-07
IPC分类号： C07K5/08 , A61K31/19 , A61K45/06 , C07D405/14 , C07D405/10 , C07B53/00 , C07C57/52 , C07C57/60 , C07C57/64 , A61K31/192 , A61K38/06 , C07C51/00 , C07K5/02 , C07K5/083 , G01N33/50 , C07C57/54
CPC分类号： C07K5/08 , A61K31/19 , A61K31/192 , A61K38/06 , A61K45/06 , C07B53/00 , C07B2200/07 , C07B2200/11 , C07C51/00 , C07C57/52 , C07C57/54 , C07C57/60 , C07C57/64 , C07D405/10 , C07D405/14 , C07K5/0205 , C07K5/0804 , G01N33/5008 , G01N2800/7028
摘要： Chiral oligomeric pentenoate amides are bio-oligomer mimetics possessing a high degree of conformation rigidity. Conformational rigidity is desirable in the design of molecules with high affinities for biological receptors and enzymes. Libraries of such oligomeric mimetics, such as of chiral oligomeric pentenoate amides can be used to probe biological systems. The present invention provides a method for preparation of chiral oligomeric pentanoate amides comprising conversion of a chiral oxazolidinone (4) to a chiral monomer of formula (1) which can be oligomerized to a chiral compound of formula (12) and so forth.
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3.发明申请公开(公告)号：US20140271488A1
公开(公告)日：2014-09-18
申请号：US14343426
申请日：2012-09-07
IPC分类号： C07K5/08 , C07C57/54 , A61K45/06 , C07C57/60 , A61K31/192 , A61K38/06 , C07C51/00 , A61K31/19
CPC分类号： C07K5/08 , A61K31/19 , A61K31/192 , A61K38/06 , A61K45/06 , C07B53/00 , C07B2200/07 , C07B2200/11 , C07C51/00 , C07C57/52 , C07C57/54 , C07C57/60 , C07C57/64 , C07D405/10 , C07D405/14 , C07K5/0205 , C07K5/0804 , G01N33/5008 , G01N2800/7028
摘要： Synthesis of compounds having varying degrees of conformational rigidity is obtained via a low cost, high yield and efficient synthetic reactions. The library of compounds is structurally diverse having at least one or more chiral centers and providing large numbers of compounds having building block diversity and substantial scaffold diversity. The compounds further provide a novel method for obtaining candidate therapeutic agents for prevention, treatment or diagnosis of diseases.
摘要翻译： 通过低成本，高产率和有效的合成反应获得具有不同程度构象刚性的化合物的合成。 化合物库在结构上不同，具有至少一个或多个手性中心并提供大量具有结构多样性和大量支架多样性的化合物。 该化合物还提供了用于获得预防，治疗或诊断疾病的候选治疗剂的新方法。
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公开(公告)号：US3801612A
公开(公告)日：1974-04-02
申请号：US3801612D
申请日：1972-09-11
申请人： ZOECON CORP
IPC分类号： C07C17/02 , C07C43/12 , C07C45/59 , C07C49/20 , C07C57/00 , C07C57/64 , C07C59/125 , C07C59/135 , A01N9/24 , C07C57/18 , C07C59/18
CPC分类号： C07C59/135 , C07C17/02 , C07C43/12 , C07C45/59 , C07C49/20 , C07C57/00 , C07C57/64 , C07C59/125 , C07C69/606 , C07C69/732 , C07C69/734 , C07C2601/02 , Y10S424/12 , C07C19/075
摘要： ALIPHATIC SUBSTITUTED ACIDS AND ESTERS WITH OLEFINS UNSATURATED AT C-2 AND ACETYLENIC UNSATURATED AT C-4, SYNTHESIS THEREOF, INTERMEDICATES THEREOF, DERIVATIVES THEREOF, AND THE CONTROL OF INSECTS.
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5.发明授权Use of certain neoflavonoids for intensifying and/or producing a sensory impression of sweetness 有权使用某些新类黄酮来加强和/或产生甜度的感觉印象公开(公告)号：US09131719B2
公开(公告)日：2015-09-15
申请号：US13616134
申请日：2012-09-14
申请人： Michael Backes , Tobias Vössing , Jakob Peter Ley , Susanne Paetz
发明人： Michael Backes , Tobias Vössing , Jakob Peter Ley , Susanne Paetz
IPC分类号： A23L1/236 , A61K47/22 , A61K8/49 , A61Q19/00 , A23L1/22 , A23L1/226 , C07D311/20 , C07C57/52 , C07C57/60 , C07C57/64
CPC分类号： A23L1/2363 , A23L27/204 , A23L27/2052 , A23L27/88 , A61K8/498 , A61K47/22 , A61K2800/10 , A61Q19/00 , C07C57/52 , C07C57/60 , C07C57/64 , C07D311/20
摘要： The present invention primarily relates to the use of one or a plurality of neoflavonoids of formula (I) and/or one or a plurality of physiologically acceptable salts of one or a plurality of neoflavonoids of formula (I) for producing a sensory impression of sweetness (i.e. an impression of sweetness) in an orally consumable preparation or for intensifying the sensory impression of sweetness of an orally consumable preparation comprising at least one further sweet-tasting and/or sweet-smelling substance. The present invention further relates to certain semifinished products and certain orally consumable preparations containing one or a plurality of neoflavonoids of formula (I) and/or one or a plurality of physiologically acceptable salts of one or a plurality of neoflavonoids of formula (I). Finally the invention also relates to a method of producing an orally consumable preparation and a method of producing and/or intensifying a sensory impression of sweetness in/of an orally consumable preparation.
摘要翻译： 本发明主要涉及式（I）的一种或多种新类黄酮和/或一种或多种式（I）的一种或多种新类黄酮的生理学上可接受的盐用于产生甜度的感觉印象 （即，甜味的印象），或增加包含至少一种另外的甜味和/或甜味物质的口服消耗品的甜味感觉印象。 本发明还涉及含有一种或多种式（I）的新类黄酮和/或一种或多种式（I）的一种或多种类黄酮的生理上可接受的盐的某些半成品和某些口服消耗品。 本发明还涉及一种口服消耗品的制造方法以及口服消耗品的生产和/或加强感觉感觉的方法。
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公开(公告)号：US3412162A
公开(公告)日：1968-11-19
申请号：US34825164
申请日：1964-02-28
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