公开(公告)号：US20230097637A1

公开(公告)日：2023-03-30

申请号：US17836258

申请日：2022-06-09

申请人： Bausch + Lomb Ireland Limited

发明人： Alok Kumar Awasthi ,  Kristen Rae Hovinga ,  Emily Abrams Gabriel ,  Kevin Jacob DeRyke ,  Jade J. Russell ,  Alana Ingham

IPC分类号： G02C7/10 ,  G02C7/04 ,  A61L12/14 ,  C07D279/08 ,  C07C301/02 ,  C07D205/06 ,  C07D409/06 ,  C07D403/10 ,  C07D403/14

摘要： A method for preparing an ophthalmic device for slowing, inhibiting or preventing myopia progression involves (a) soaking an ophthalmic device in one or more first solvent solutions to swell the ophthalmic device; (b) soaking the swelled ophthalmic device in one or more second solvents solutions comprising one or more red-light blocking compounds blocking greater than about 5% to about 25% of red-light transmission through the ophthalmic device at a wavelength of from about 550 nanometers (nm) to about 800 nm to de-swell the swelled ophthalmic device and entrap the one or more red-light blocking compounds in the de-swelled ophthalmic device; and (c) sterilizing the de-swelled ophthalmic device.

公开(公告)号：US4148820A

公开(公告)日：1979-04-10

申请号：US786177

申请日：1977-04-11

申请人： Samuel Evans

发明人： Samuel Evans

IPC分类号： C07C67/00 ,  C07C69/96 ,  C07C301/00 ,  C07C301/02 ,  C07C303/06 ,  C07C303/08 ,  C07C303/24 ,  C07C305/22 ,  C07C325/00 ,  C07C329/00 ,  C07C329/04 ,  C07F9/08 ,  C07F9/12 ,  C07F9/145 ,  C07F9/32 ,  C07F9/40 ,  C07F9/48 ,  C08K5/00 ,  C08K5/10 ,  C08K5/13 ,  C08K5/36 ,  C08K5/51 ,  C08K5/52 ,  C08L23/00 ,  C08L101/00 ,  C09K15/08 ,  C09K15/14 ,  C09K15/32

CPC分类号： C09K15/322 ,  C07C301/02 ,  C07C305/24 ,  C07C323/16 ,  C07C329/04 ,  C07F9/12 ,  C07F9/145 ,  C07F9/4075 ,  C07F9/4084 ,  C07F9/4875 ,  C08K5/005 ,  C08K5/51 ,  C09K15/14

摘要： Phenols of the formula I ##STR1## wherein N HAS A VALUE FROM 1 TO 15,Each of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 independently is a hydrogen atom, a C.sub.1 -C.sub.18 -alkyl group, an aryl group, a C.sub.5 -C.sub.12 -cyclo-alkyl group or a C.sub.7 -C.sub.13 -aralkyl group,R.sub.5 is a hydrogen atom or a C.sub.1 -C.sub.18 -alkyl group,Y is a carbonyl, thiocarbonyl, sulphinyl, sulphonyl, --P(OR.sub.7)--P(.dbd.O)(OR.sub.7)--, --P(.dbd.O)(R.sub.7)-- or --P(R.sub.7)-- group, and R.sub.6 is a radical --CHR.sub.8 --CHR.sub.9 --S--CR.sub.10 R.sub.11 R.sub.12, wherein each of R.sub.8 and R.sub.9 independently is a hydrogen atom or a C.sub.1 -C.sub.6 -alkyl group, R.sub.10 is a hydrogen atom, a C.sub.1 -C.sub.19 -alkyl group, a C.sub.2 -C.sub.4 -alkenyl group or an aryl group, R.sub.11 is a hydrogen atom or a methyl group and R.sub.12 is a hydrogen atom or a methyl group, or, if R.sub.11 is a hydrogen atom, is a C.sub.2 -C.sub.6 -alkyl group, or, if R.sub.10 is a hydrogen atom, R.sub.11 and R.sub.12 together with the carbon atom to which they are attached represent a cycloalkyl group, or R.sub.10, R.sub.11 and R.sub.12 together with the carbon atom to which they are attached represent an aryl group, or if Y is a thiocarbonyl, sulphinyl or sulphonyl group,R.sub.6 can also be a hydrogen atom or a C.sub.1 -C.sub.18 -alkyl group or an aryl group, andR.sub.7 is a hydrogen atom, a C.sub.1 -C.sub.18 -alkyl group or an aryl group, as stabilizers for organic material.

摘要翻译： 式I的化合物（I）其中N为1至15，R 1，R 2，R 3和R 4各自独立地为氢原子，C 1 -C 18烷基，芳基 ，C 5 -C 12 - 环烷基或C 7 -C 13 - 芳烷基，R 5是氢原子或C 1 -C 18烷基，Y是羰基，硫代羰基，亚磺酰基，磺酰基，-P（OR 7） - P（= O）（OR 7） - ， - P（= O）（R 7） - 或-P（R 7） - 基，R 6是基团-CHR 8 -CHR 9 -S-CR 10 R 11 R 12，其中R 8和R 9各自独立地 是氢原子或C1-C6烷基，R10是氢原子，C1-C19 - 烷基，C2-C4-烯基或芳基，R11是氢原子或甲基，R12 或者如果R 11为氢原子，则为C 2 -C 6 - 烷基，或者如果R 10为氢原子，则R 11和R 12与它们所连接的碳原子一起代表 环烷基或R 10，R 11和R 12与它们所连接的碳原子一起表示芳基，或者如果Y是硫代羰基，则 二苯基或磺酰基，R6也可以是氢原子或C1-C18烷基或芳基，R7是氢原子，C1-C18烷基或芳基作为有机材料的稳定剂。

公开(公告)号：US20140357896A1

公开(公告)日：2014-12-04

申请号：US14289686

申请日：2014-05-29

申请人： SAN-APRO LTD. ,  TOKYO OHKA KOGYO CO., LTD.

发明人： Issei Suzuki ,  Takuya Ikeda ,  Yusaku Takashima ,  Takeshi Furuta ,  Yoshitaka Komuro ,  Yoshiyuki Utsumi ,  Takaaki Kaiho ,  Toshiaki Hato

IPC分类号： C07C323/09 ,  C07C311/09 ,  C07C301/02 ,  C07C301/00

CPC分类号： C07C309/06 ,  C07C309/19 ,  C07C311/48 ,  C07C317/04 ,  C07C381/12 ,  C07C2602/42

摘要： Provided is a novel sulfonium salt that has high solubility in a solvent and has high light sensitivity to, especially, light having a wavelength not longer than deep-UV (254 nm) and a novel photo-acid generator comprising the sulfonium salt. The invention relates to a sulfonium salt represented by the following general formula (1) and a novel photo-acid generator comprising the sulfonium salt. wherein R1 represents an electron withdrawing group; R2 and R3 each independently represent an alkyl group having 1 to 5 carbon atoms, an alkoxy group, an acyl group, a halogenated alkyl group, a halogen atom, a hydroxyl group, a cyano group, or a nitro group; p and q each independently represent an integer of 0 to 5; and X− represents a monovalent counter anion.

摘要翻译： 提供了一种在溶剂中具有高溶解度并对具有高于深UV（254nm）的波长的光，特别是具有不长于深UV（254nm）的光的光的高灵敏度的新型锍盐和包含锍盐的新型光酸产生剂。 本发明涉及由以下通式（1）表示的锍盐和包含锍盐的新型光酸产生剂。 其中R1表示吸电子基团; R2和R3各自独立地表示碳原子数1〜5的烷基，烷氧基，酰基，卤代烷基，卤素原子，羟基，氰基或硝基。 p和q各自独立地表示0〜5的整数， X-表示一价抗衡阴离子。

公开(公告)号：US20100056814A1

公开(公告)日：2010-03-04

申请号：US12231220

申请日：2008-08-29

申请人： Te Chang ,  Gary A. Sawyer

发明人： Te Chang ,  Gary A. Sawyer

IPC分类号： C07C301/02

CPC分类号： C07D301/06 ,  C07D301/08 ,  C07D301/32

摘要： A process for making propylene oxide from propylene is disclosed. The process comprises reacting propylene, oxygen, and hydrogen in the presence of a catalyst and a solvent to produce a reaction mixture comprising propylene oxide. Separation of propylene, oxygen, hydrogen, and propylene oxide from the reaction mixture results in a residual mixture comprising methanol. A portion of the residual mixture is recycled to the reaction. A portion of the residual mixture is distilled to generate a distilled methanol stream, which is recycled to the reaction.

摘要翻译： 公开了一种从丙烯制备环氧丙烷的方法。 该方法包括在催化剂和溶剂的存在下使丙烯，氧和氢反应以产生包含环氧丙烷的反应混合物。 从反应混合物中分离丙烯，氧，氢和环氧丙烷导致包含甲醇的残留混合物。 将一部分残余混合物再循环至反应。 将一部分残余混合物蒸馏以产生蒸馏的甲醇流，将其再循环至反应中。

公开(公告)号：US5347040A

公开(公告)日：1994-09-13

申请号：US988435

申请日：1992-12-09

申请人： Arnost Reiser ,  Xiaohua He

发明人： Arnost Reiser ,  Xiaohua He

IPC分类号： C07C25/02 ,  C07C309/43 ,  C07C381/12 ,  C07F9/54 ,  C08F2/50 ,  C08G59/68 ,  C08G65/10 ,  C09K3/00 ,  G03F7/029 ,  C07C69/017 ,  C07C301/00 ,  C07C301/02 ,  C07F9/40

CPC分类号： C07C309/43 ,  C07C381/12 ,  C08F2/50 ,  C08G59/68 ,  C08G65/105 ,  Y10S430/115 ,  Y10S430/127

摘要： Onium salt capable of generating acid upon exposure to actinic radiation having the following structure:(R.sub.1).sub.a (R.sub.2).sub.b (R.sub.3).sub.c Q.sup.+ --A--M.sup.+ X.sup.- --B--X'.sup.-where:Q is S;R.sub.1, R.sub.2 and R.sub.3 are independently substituted or unsubstituted aromatic, aliphatic, or aralkyl groups having 7-18 carbon atoms;M.sup.+ is a cationic organic radical;A is a divalent radical selected from the group of hindered alkylene groups, substituted or unsubstituted aromatic or aralkyl groups;B is a divalent aromatic sensitizer which absorbs radiation having a wavelength longer than 300 nm and is capable of transferring an electron to Q,x.sup.- and X'.sup.- are anionic groups; and wherein A provides a spatial separation between Q and M, and B provides a spatial separation between X and X', such that the spatial separation provided by A between Q and M is substantially the same as the spatial separation provided by B between X and X'.

摘要翻译： （R1）a（R2）b（R3）cQ + -A-M + X-B-X'-其中：Q为S; R1，R2和R3独立地为具有7-18个碳原子的取代或未取代的芳族，脂族或芳烷基; M +是阳离子有机基团; A是选自受阻亚烷基，取代或未取代的芳族或芳烷基的二价基团; B是吸收波长大于300nm并且能够将电子传递到Q的辐射的二价芳香族敏化剂，X和X'是阴离子基团; 并且其中A提供Q和M之间的空间间隔，并且B提供X和X'之间的空间间隔，使得由Q和M之间的A提供的空间分隔基本上与由X和X之间的B提供的空间分离相同 X'。

公开(公告)号：US20230192610A1

公开(公告)日：2023-06-22

申请号：US17970533

申请日：2022-10-20

申请人： Massachusetts Institute of Technology

发明人： Jeremiah A. Johnson ,  Hung Vanthanh Nguyen ,  Peyton Shieh ,  Wencong Wang ,  Bin Liu ,  Valerie Lensch ,  Landon Kilgallon ,  Yutong Dai ,  Samantha Lynn Kristufek

IPC分类号： C07D207/277 ,  C07C301/02 ,  C07C233/60 ,  C07D257/08

CPC分类号： C07D207/277 ,  C07C301/02 ,  C07C233/60 ,  C07D257/08

摘要： The present disclosure provides enynes, end-functionalized polymers, conjugates, methods of preparation, compositions, kits, and methods of use. The conjugates comprise at least (1) a peptide (e.g., an antibody), protein, nucleoprotein, mucoprotein, lipoprotein, glycoprotein, or polynucleotide; and (2) a polymer comprising a pharmaceutical agent. The conjugates may be useful in delivering (e.g., targeted delivering) the pharmaceutical agent to a subject in need thereof or cell or treating, preventing, or diagnosing a disease.

公开(公告)号：US09522879B2

公开(公告)日：2016-12-20

申请号：US14402573

申请日：2013-05-23

申请人： KOC SOLUTION CO., LTD

发明人： Dong Gyu Jang ,  Soo Gyun Roh ,  Jong Hyo Kim

IPC分类号： C07C319/20 ,  C07C301/02 ,  C08G18/38 ,  G02B1/04 ,  C07C319/14 ,  C07C319/08 ,  C07C321/14 ,  C07C323/12 ,  C08L81/00 ,  C07C321/08 ,  C07D301/02 ,  C08G18/75 ,  C08G18/76

CPC分类号： C07C319/20 ,  C07C319/08 ,  C07C319/14 ,  C07C321/08 ,  C07C323/12 ,  C07D301/02 ,  C08G18/3868 ,  C08G18/3876 ,  C08G18/755 ,  C08G18/7671 ,  C08G18/7692 ,  G02B1/041 ,  G02B1/043 ,  C07C321/14 ,  C08L75/04 ,  C08L81/00

摘要： The present invention relates to novel methods for preparing a polythiol compound for use in an optical material and polymerizable compositions including a polythiol compound prepared by the methods. According to the methods, a polythiol compound with uniform color, high purity and high quality can be prepared at reduced cost. The polymerizable compositions can be used to manufacture clear, transparent optical lenses with good heat resistance and excellent optical properties.

摘要翻译： 本发明涉及制备用于光学材料的多硫醇化合物的新方法和包括通过该方法制备的多硫醇化合物的可聚合组合物。 根据该方法，可以以降低的成本制备具有均匀的颜色，高纯度和高质量的多硫醇化合物。 可聚合组合物可用于制造透明，透明的光学透镜，具有良好的耐热性和优异的光学性能。

公开(公告)号：US4868338A

公开(公告)日：1989-09-19

申请号：US165704

申请日：1988-03-08

申请人： Ambrogio Magni ,  Giuseppina Visentin

发明人： Ambrogio Magni ,  Giuseppina Visentin

IPC分类号： C07D233/84 ,  B01J27/125 ,  B01J27/135 ,  B01J27/138 ,  C07B61/00 ,  C07C45/00 ,  C07C45/46 ,  C07C49/84 ,  C07C67/00 ,  C07C67/035 ,  C07C67/08 ,  C07C67/10 ,  C07C67/24 ,  C07C301/00 ,  C07C301/02 ,  C07C303/22

CPC分类号： C07C45/46 ,  C07C49/84

摘要： The acylation of a naphthalene compound, substituted in the 2-position with an electron-donating group, with a reactive derivative of a lower aliphatic acid, in an aprotic organic diluent and in the presence of a Friedel Crafts catalyst consisting of a halide of an element having at least two valences, is improved when maintaining constant at any time the molar ratio of the naphthalene compound to the acylating agent and that of the acylating agent to the Friedel Crafts catalyst within specific ranges.

公开(公告)号：US12084415B2

公开(公告)日：2024-09-10

申请号：US17970533

申请日：2022-10-20

申请人： Massachusetts Institute of Technology

发明人： Jeremiah A. Johnson ,  Hung Vanthanh Nguyen ,  Peyton Shieh ,  Wencong Wang ,  Bin Liu ,  Valerie Lensch ,  Landon Kilgallon ,  Yutong Dai ,  Samantha Lynn Kristufek

IPC分类号： C08G61/08 ,  C07C233/60 ,  C07C301/02 ,  C07D207/277 ,  C07D257/08

CPC分类号： C07D207/277 ,  C07C233/60 ,  C07C301/02 ,  C07D257/08 ,  C08G61/08 ,  C08G2261/136 ,  C08G2261/1424 ,  C08G2261/1432 ,  C08G2261/1646 ,  C08G2261/354 ,  C08G2261/418

摘要： The present disclosure provides enynes, end-functionalized polymers, conjugates, methods of preparation, compositions, kits, and methods of use. The conjugates comprise at least (1) a peptide (e.g., an antibody), protein, nucleoprotein, mucoprotein, lipoprotein, glycoprotein, or polynucleotide; and (2) a polymer comprising a pharmaceutical agent. The conjugates may be useful in delivering (e.g., targeted delivering) the pharmaceutical agent to a subject in need thereof or cell or treating, preventing, or diagnosing a disease.

公开(公告)号：US20170306517A1

公开(公告)日：2017-10-26

申请号：US15518182

申请日：2015-10-08

申请人： SOLVAY SPECIALTY POLYMERS ITALY S.P.A.

发明人： Paula COJOCARU ,  Cristiano MONZANI ,  Marco APOSTOLO ,  Francesco Maria TRIULZI ,  Vito TORTELLI ,  Elvira GOMEZ VALENTIN ,  Elisa VALLES GIMENEZ

IPC分类号： C25D3/66 ,  C07C311/09 ,  C07C301/02 ,  C07F19/00 ,  C07C211/63

CPC分类号： C25D3/66 ,  C07C211/63 ,  C07C301/02 ,  C07C311/09 ,  C07D213/20 ,  C07F19/005 ,  C25D3/665

摘要： The present invention pertains to a composition comprising: (I) at least one ionic liquid of formula (1-a) or of formula (1-b): [RF-CFR′F-SO3]− A+ (1-a) [(RF-CFR′F—SO2)2N]− (1-b) wherein: -RF is a C1-C25 fluoroalkyi group, optionally comprising one or more than one catenary ethereal oxygen atoms, -R′F is —F or a —CF3 group, and -A+ is an organic cation selected from the group consisting of tetraalkylammonium, pyridinium, imidazolium, piperidinium, pyrrolidinium, amidinium and guanidinium groups, and (II) at least one metal salt of formula (II): MeB, (H) wherein: -Mem+ is a metal cation deriving from a metal (Me) selected from the group consisting of groups IB, MB, IVB, VB, VIB, MIA, IVA and VIII (8, 9, 10) of the Periodic Table, preferably from the group consisting of groups IVB, VB, VIB and IMA of the Periodic Table, wherein m is the valence of said metal cation, and —Bn− is an inorganic anion, wherein n is the valence of said inorganic anion. The present invention also pertains to the use of said composition in an electrodeposition process and to the metal-coated assembly thereby provided.