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公开(公告)号：US09533005B2
公开(公告)日：2017-01-03
申请号：US14322861
申请日：2014-07-02
申请人： Xin Ji
发明人： Xin Ji , Cheng Xing , Xueshen Shi
IPC分类号： A61K31/718 , C08B31/00 , C08B31/08 , C08B31/02 , C08B33/04 , C08B31/10 , C08B31/16 , C08B35/02 , C08B33/06 , C08B35/06 , C08B35/04 , C08B33/02 , C08B31/12 , C08B31/04 , C08B30/20 , C08B30/00 , A61K31/738 , A61L24/08 , A61L26/00 , A61K45/06
CPC分类号： A61L31/042 , A61K9/0014 , A61K9/14 , A61K9/19 , A61K31/718 , A61K31/738 , A61K45/06 , A61L24/0015 , A61L24/0036 , A61L24/0073 , A61L24/08 , A61L24/104 , A61L26/0023 , A61L26/0085 , A61L31/045 , A61L31/125 , A61L2300/406 , A61L2400/04 , A61L2430/34 , C08B30/00 , C08B30/20 , C08B31/00 , C08B31/003 , C08B31/02 , C08B31/04 , C08B31/08 , C08B31/10 , C08B31/12 , C08B31/16 , C08B33/02 , C08B33/04 , C08B33/06 , C08B35/02 , C08B35/04 , C08B35/06 , C08L3/04 , C08L3/18 , C08L89/06 , Y10T428/2982
摘要： A modified starch material for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.
摘要翻译： 当作为生物相容性改性淀粉应用于动物组织时，用于生物相容性止血，生物相容性粘附预防，组织愈合促进，可吸收外科伤口密封和组织粘合的改性淀粉材料。 改性淀粉材料产生止血，减少伤口出血，外渗和组织渗出，保持伤口表面或伤口相对湿润或干燥，抑制细菌生长和炎症反应，减少组织炎症，缓解患者疼痛 。 不参与止血活性的任何多余的改性淀粉容易溶解，并在操作期间通过盐水冲洗冲洗掉。 手术伤口治疗后，对伤口，创伤和紧急伤口进行治疗，改性淀粉止血材料被身体快速吸收，无与纱布和绷带去除有关的并发症。
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公开(公告)号：US08912168B2
公开(公告)日：2014-12-16
申请号：US14018895
申请日：2013-09-05
申请人： Xin Ji
发明人： Xin Ji , Cheng Xing , Xueshen Shi
IPC分类号： A61K31/718 , C08B31/02 , C08B31/04 , C08B31/08 , C08B31/10 , C08B31/12 , C08B33/02 , C08B33/04 , C08B33/06 , C08B35/02 , C08B35/04 , C08B35/06 , A61K31/738 , C08B31/16 , C08B30/00 , A61L24/08 , A61L26/00
CPC分类号： A61L31/042 , A61K9/0014 , A61K9/14 , A61K9/19 , A61K31/718 , A61K31/738 , A61K45/06 , A61L24/0015 , A61L24/0036 , A61L24/0073 , A61L24/08 , A61L24/104 , A61L26/0023 , A61L26/0085 , A61L31/045 , A61L31/125 , A61L2300/406 , A61L2400/04 , A61L2430/34 , C08B30/00 , C08B30/20 , C08B31/00 , C08B31/003 , C08B31/02 , C08B31/04 , C08B31/08 , C08B31/10 , C08B31/12 , C08B31/16 , C08B33/02 , C08B33/04 , C08B33/06 , C08B35/02 , C08B35/04 , C08B35/06 , C08L3/04 , C08L3/18 , C08L89/06 , Y10T428/2982
摘要： A modified starch material for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.
摘要翻译： 当作为生物相容性改性淀粉应用于动物组织时，用于生物相容性止血，生物相容性粘附预防，组织愈合促进，可吸收外科伤口密封和组织粘合的改性淀粉材料。 改性淀粉材料产生止血，减少伤口出血，外渗和组织渗出，保持伤口表面或伤口相对湿润或干燥，抑制细菌生长和炎症反应，减少组织炎症，缓解患者疼痛 。 不参与止血活性的任何多余的改性淀粉容易溶解，并在操作期间通过盐水冲洗冲洗掉。 手术伤口治疗后，对伤口，创伤和紧急伤口进行治疗，改性淀粉止血材料被身体快速吸收，无与纱布和绷带去除有关的并发症。
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公开(公告)号：US10195312B2
公开(公告)日：2019-02-05
申请号：US15427801
申请日：2017-02-08
申请人： Xin Ji
发明人： Xin Ji , Cheng Xing , Xueshen Shi
IPC分类号： A61K31/718 , A61L31/04 , C08B31/08 , C08B31/02 , C08B33/04 , C08B31/10 , C08B31/16 , C08B35/02 , C08B33/06 , C08B35/06 , C08B35/04 , C08B33/02 , C08B31/12 , C08B31/04 , C08B30/20 , C08B31/00 , C08B31/18 , C08B30/00 , A61K31/738 , A61L24/08 , A61L26/00 , A61K45/06 , A61K9/14 , C08L3/04 , C08L3/18 , C08L89/06 , A61K9/00 , A61K9/19 , A61L24/00 , A61L24/10 , A61L31/12
摘要： A modified starch material for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.
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公开(公告)号：US10076590B2
公开(公告)日：2018-09-18
申请号：US15359255
申请日：2016-11-22
申请人： Xin Ji
发明人： Xin Ji , Cheng Xing , Xueshen Shi
IPC分类号： A61K31/718 , A61L31/04 , C08B31/08 , C08B31/02 , C08B33/04 , C08B31/10 , C08B31/16 , C08B35/02 , C08B33/06 , C08B35/06 , C08B35/04 , C08B33/02 , C08B31/12 , C08B31/04 , C08B30/20 , C08B31/00 , C08B30/00 , A61K31/738 , A61L24/08 , A61L26/00 , A61K45/06 , A61K9/14 , C08L3/04 , C08L3/18 , C08L89/06 , A61K9/00 , A61K9/19 , A61L24/00 , A61L24/10 , A61L31/12
CPC分类号： A61L31/042 , A61K9/0014 , A61K9/14 , A61K9/19 , A61K31/718 , A61K31/738 , A61K45/06 , A61L24/0015 , A61L24/0036 , A61L24/0073 , A61L24/08 , A61L24/104 , A61L26/0023 , A61L26/0085 , A61L31/045 , A61L31/125 , A61L2300/406 , A61L2400/04 , A61L2430/34 , C08B30/00 , C08B30/20 , C08B31/00 , C08B31/003 , C08B31/02 , C08B31/04 , C08B31/08 , C08B31/10 , C08B31/12 , C08B31/16 , C08B31/18 , C08B33/02 , C08B33/04 , C08B33/06 , C08B35/02 , C08B35/04 , C08B35/06 , C08L3/04 , C08L3/18 , C08L89/06 , Y10T428/2982
摘要： A modified starch material for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.
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公开(公告)号：US09181352B2
公开(公告)日：2015-11-10
申请号：US13322372
申请日：2010-05-26
申请人： Bert Volkert , André Lehmann
发明人： Bert Volkert , André Lehmann
IPC分类号： C08B31/02 , C08B33/02 , C08B35/02 , C08B31/16 , C08B33/06 , C08B35/06 , C08B31/00 , C08B33/00 , C08B35/00 , C07H1/00 , C07H3/00 , C08B37/00 , C08B31/04 , C08B3/00
摘要： The invention relates to a method for producing polysaccharide esters or polysaccharide mixed esters, in which a polysaccharide or a modified polysaccharide is converted with at least one esterification reagent and at least one halogenide component, an imidazole compound which is generated in situ being used as catalyst.
摘要翻译： 本发明涉及一种生产多糖酯或多糖混合酯的方法，其中多糖或改性多糖用至少一种酯化试剂和至少一种卤化物组分转化，原位产生的咪唑化合物用作催化剂 。
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公开(公告)号：US09687501B2
公开(公告)日：2017-06-27
申请号：US13894396
申请日：2013-05-14
申请人： Xin Ji , Cheng Xing , Xueshen Shi , Jianping Chen
发明人： Xin Ji , Cheng Xing , Xueshen Shi , Jianping Chen
IPC分类号： A61K31/718 , A61L24/00 , A61L26/00 , A61K9/14 , C08L3/18 , C08L3/04 , C08L89/06 , C08B31/12 , C08B31/08 , C08B31/02 , C08B33/04 , C08B31/10 , C08B31/16 , C08B35/02 , C08B33/06 , C08B35/06 , C08B35/04 , C08B33/02 , C08B31/04 , C08B30/20 , C08B31/00 , C08B30/00 , A61K31/738 , A61L24/08 , A61K45/06 , A61K9/19 , C08B31/06 , A61K9/00
CPC分类号： A61L31/042 , A61K9/0014 , A61K9/14 , A61K9/19 , A61K31/718 , A61K31/738 , A61K45/06 , A61L24/0015 , A61L24/0036 , A61L24/0073 , A61L24/08 , A61L24/104 , A61L26/0023 , A61L26/0085 , A61L31/045 , A61L31/125 , A61L2300/406 , A61L2400/04 , A61L2430/34 , C08B30/00 , C08B30/20 , C08B31/00 , C08B31/003 , C08B31/02 , C08B31/04 , C08B31/08 , C08B31/10 , C08B31/12 , C08B31/16 , C08B33/02 , C08B33/04 , C08B33/06 , C08B35/02 , C08B35/04 , C08B35/06 , C08L3/04 , C08L3/18 , C08L89/06 , Y10T428/2982
摘要： A modified starch material is arranged for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.
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7.发明授权Polysaccharide derivative and separating agent for optical isomer containing the same 有权多糖衍生物和含有其的旋光异构体分离剂公开(公告)号：US09499638B2
公开(公告)日：2016-11-22
申请号：US14067419
申请日：2013-10-30
IPC分类号： C08B15/00 , C08B15/06 , C08B33/02 , B01J20/26 , B01J20/285 , B01J20/286 , B01J20/29 , B01J20/32 , C07B57/00 , C08B33/00 , C08B33/04 , C08B33/06
CPC分类号： C08B33/02 , B01J20/262 , B01J20/265 , B01J20/285 , B01J20/286 , B01J20/29 , B01J20/3272 , B01J20/328 , C07B57/00 , C08B33/00 , C08B33/04 , C08B33/06
摘要： The present invention provides: a polysaccharide derivative containing a structure wherein hydrogen atoms in a hydroxyl group at the 2-position and the 3-position of a structure unit of polysaccharide are substituted with different substituents respectively represented by a specific general formula and a separating agent for optical isomers which contains such a polysaccharide derivative. The present invention can provide a novel polysaccharide derivative which has excellent optical isomer separating ability, making it suitable as a separating agent for optical isomers, and can provide a separating agent for optical isomers which contains the polysaccharide derivative.
摘要翻译： 本发明提供一种含有多糖衍生物的多糖衍生物，其特征在于，其特征在于，通过分别由特定的通式表示的不同的取代基和分离剂来代替多糖的结构单元的2-位和3-位的羟基上的氢原子 含有这种多糖衍生物的光学异构体。 本发明可以提供具有优异的旋光异构体分离能力的新型多糖衍生物，使其适合作为光学异构体的分离剂，并且可以提供含有多糖衍生物的旋光异构体的分离剂。
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公开(公告)号：US4167621A
公开(公告)日：1979-09-11
申请号：US918709
申请日：1978-06-26
申请人： Martin M. Tessler
发明人： Martin M. Tessler
CPC分类号： C08B31/12
摘要： Starch ether derivatives are prepared by reacting a starch base with about 0.5-100% by weight of a neutralized alkyl ester of 3-chloro-2-sulfopropionic acid, based on dry starch, and then isolating the resultant starch derivative. The 2-sulfo-2-carboxyethyl starch ethers thus prepared may be utilized in many applications, and are particularly useful as wet-end additives in paper manufacturing at low pH.
摘要翻译： 淀粉醚衍生物通过使淀粉碱与约0.5-100重量％的中和的3-氯-2-磺基丙酸烷基酯（基于干淀粉）反应制备，然后分离得到的淀粉衍生物。 如此制备的2-磺基-2-羧乙基淀粉醚可用于许多应用，并且在低pH下在纸制造中特别适用于湿端添加剂。
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