公开(公告)号：US20220275112A1

公开(公告)日：2022-09-01

申请号：US17680581

申请日：2022-02-25

申请人： NUTRITION & BIOSCIENCES USA 4, INC.

发明人： Qiong Cheng ,  Robert DiCosimo ,  Arthur Ouwehand ,  Zheng You ,  Mark S. Payne ,  Jian Ping Lai ,  Kristin Ruebling-Jass ,  Steven Cary Rothman

IPC分类号： C08B37/00 ,  A23L29/30 ,  A23L33/21 ,  A61K31/716 ,  C12P19/04 ,  C12P19/08 ,  C12P19/18 ,  C08L5/00 ,  A23L7/135 ,  A23L7/126 ,  A23L21/10 ,  A21D13/45 ,  A21D13/80 ,  A23C9/13 ,  A23G3/36 ,  A23G9/32 ,  A23L2/52 ,  C12N9/10 ,  C12N9/44

摘要： An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.

公开(公告)号：US11261264B2

公开(公告)日：2022-03-01

申请号：US16451501

申请日：2019-06-25

申请人： NUTRITION & BIOSCIENCES USA 4, INC.

发明人： Qiong Cheng ,  Robert DiCosimo ,  Arthur Ouwehand ,  Zheng You ,  Mark S. Payne ,  Jian Ping Lai ,  Kristin Ruebling-Jass ,  Steven Cary Rothman

IPC分类号： C08B37/00 ,  A21D13/45 ,  A21D13/80 ,  A23C9/13 ,  A23G3/36 ,  A23G9/32 ,  A23L2/52 ,  A23L2/10 ,  C08L5/00 ,  C12N9/10 ,  C12N9/44 ,  C12P19/04 ,  C12P19/08 ,  A23L29/30 ,  A23L33/21 ,  A61K31/716 ,  C12P19/18 ,  A23L7/135 ,  A23L7/126 ,  A23L21/10

摘要： An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.

公开(公告)号：US11155847B2

公开(公告)日：2021-10-26

申请号：US15505536

申请日：2015-08-22

申请人： ISOThrive LLC ,  Board of Supervisors of Louisiana State University and Agricultural and Mechanical College

发明人： Lee Madsen, II ,  Jack Oswald ,  Donal F Day ,  Young Hwan Moon

IPC分类号： C12P19/04 ,  C12P19/08 ,  C08B37/00 ,  C12N9/44 ,  C12P19/18 ,  C12N1/20 ,  A61K31/715 ,  C12P19/20 ,  C12R1/01

摘要： The present invention provides a method for the production of oligosaccharides by the fermentation of dextran-sucrase-producing microorganisms with sucrose and maltose. The disclosed process allows for the control of the final composition of the isomaltooligosaccharides by adjustments to pH and the initial ratio of sucrose to maltose.

公开(公告)号：US20210071217A1

公开(公告)日：2021-03-11

申请号：US16856559

申请日：2020-04-23

申请人： DUPONT INDUSTRIAL BIOSCIENCES USA, LLC

发明人： JAYME L. PAULLIN ,  RAKESH NAMBIAR

IPC分类号： C12P19/08 ,  C12P19/18 ,  C08L5/02 ,  C08B37/02 ,  C08B37/16

摘要： Compositions are disclosed herein comprising at least one dextran ether compound that comprises uncharged, anionic, and/or cationic organic groups. The degree of substitution of one or more dextran ether compounds is about 0.0025 to about 3.0. Dextran from which the disclosed ether compounds can be derived can have a weight-average molecular weight of about 50-200 million Daltons and/or a z-average radius of gyration of about 200-280 nm. Also disclosed are methods of producing dextran ether compounds, as well as methods of using these ether compounds in various applications.

公开(公告)号：US10808269B2

公开(公告)日：2020-10-20

申请号：US16281225

申请日：2019-02-21

申请人： DANISCO US INC

发明人： Zheyong Yu ,  Slavko Kralj ,  Zhenghong Zhang ,  Laurie A. Howe

IPC分类号： C12P19/08 ,  C12N9/10 ,  C12P19/04 ,  C12P19/18

摘要： Reaction compositions are disclosed herein comprising at least water, beta-glucose-1-phosphate (beta-G1P), an acceptor molecule, and an alpha-1,3-glucan phosphorylase enzyme. These reactions can synthesize oligosaccharides and polysaccharides with alpha-1,3 glycosidic linkages. Further disclosed are alpha-1,3-glucan phosphorylase enzymes and methods of use thereof.

公开(公告)号：US20190185893A1

公开(公告)日：2019-06-20

申请号：US16218518

申请日：2018-12-13

申请人： E I DU PONT DE NEMOURS AND COMPANY

发明人： RONG GUAN ,  JAMES JOSHUA OHANE ,  NIKITA ILTCHENKO ,  YEFIM BRUN ,  BRIAN MCCAULEY ,  LAURIE A. HOWE ,  YOUGEN LI

IPC分类号： C12P19/08 ,  C12P19/18 ,  C08B37/02 ,  C08B37/00 ,  C08J5/18 ,  C11D3/37

CPC分类号： C12P19/08 ,  C08B37/0009 ,  C08B37/0021 ,  C08J5/18 ,  C08J2305/00 ,  C08J2305/02 ,  C08L5/02 ,  C11D3/3707 ,  C12P19/18

摘要： Compositions are disclosed herein comprising a graft copolymer that comprises: (i) a backbone comprising dextran that has been modified with about 1%-25% alpha-1,2 branches, and (ii) one or more alpha-1,3-glucan side chains comprising at least about 50% alpha-1,3 glycosidic linkages. Further disclosed are reactions for producing such graft copolymers, as well as their use in derivatives, films and various other applications.

公开(公告)号：US10017748B2

公开(公告)日：2018-07-10

申请号：US15190282

申请日：2016-06-23

申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  INSTITUT NATIONAL DE RECHERCHE AGRONOMIQUE ,  INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE

发明人： Pierre F. Monsan ,  Magali Remaud-Simeon ,  Gabrielle Potocki-Veronese ,  Claire Moulis

IPC分类号： C08B37/02 ,  C07H1/00 ,  C07H21/04 ,  C12N9/10 ,  C12N9/24 ,  C12N9/46 ,  C12P21/06 ,  C12P19/12 ,  C12P19/04 ,  C12P19/08 ,  C12P19/18 ,  C07K1/00 ,  C07H3/06

CPC分类号： C12N9/1051 ,  C07H3/06 ,  C07K2319/35 ,  C08B37/0021 ,  C12P19/04 ,  C12P19/08 ,  C12P19/12 ,  C12P19/18 ,  C12Y204/01005 ,  Y02P20/52

摘要： The present invention relates to a recombinant process for the production of truncated or mutated dextransucrases while conserving the enzymatic activity or their specificity in the synthesis of the α-1,6 bonds. The present invention relates to nucleic acid sequences of truncated or mutated dextransucrases, vectors containing the nucleic acid sequences and host cells transformed by sequences encoding truncated or mutated dextransucrases. In another aspect, the invention concerns a method for producing, in a recombinant manner, truncated or mutated dextransucrases which conserve their enzymatic activity or which conserve their specificity in the synthesis of α-1,6 bonds and can produce, from saccharose, dextrans with high molar mass and modified rheological properties compared with the properties of dextran obtained with the native enzyme and isomalto-oligosaccharides with a controlled molar mass and dextrans. The dextrans and isomalto-oligosaccharides of the invention can be used namely as texturing agents or as prebiotics.

公开(公告)号：US20180049457A1

公开(公告)日：2018-02-22

申请号：US15313238

申请日：2015-05-22

申请人： E I DU PONT DE NEMOURS AND COMPANY

发明人： Qiong Cheng ,  Robert Dicosimo ,  Arthur Ouwehand ,  Zheng You ,  Supaporn Suwannakham ,  Kevin D. Nagy ,  Mark S. Payne ,  Jahnavi Chandra Prasad

IPC分类号： A23L29/269 ,  C12P19/08 ,  C12P19/18 ,  A61K8/73 ,  A61K31/716 ,  A61K8/36

CPC分类号： A23L29/269 ,  A61K8/36 ,  A61K8/73 ,  A61K31/716 ,  A61K2800/10 ,  A61Q19/00 ,  C08B37/0009 ,  C08L5/00 ,  C08L2205/16 ,  C12P19/04 ,  C12P19/08 ,  C12P19/18 ,  C12Y204/01 ,  C12Y302/01011 ,  C12Y302/01059

摘要： An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.

公开(公告)号：US20170247669A1

公开(公告)日：2017-08-31

申请号：US15329941

申请日：2015-07-21

申请人： INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE TOULOUSE ,  INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  UNIVERSITE PAUL SABATIER TOULOUSE III

发明人： Marlène Vuillemin ,  Marion Claverie ,  Claire Moulis ,  Magali Remaud-Simeon ,  Pierre Monsan ,  Etienne Severac ,  Catherine Fontagne-Faucher

IPC分类号： C12N9/10 ,  C12P19/18 ,  A23L29/269 ,  A61K8/73 ,  A61K47/36 ,  A61K31/721 ,  C12P19/08 ,  C08B37/02

CPC分类号： C12N9/1051 ,  A23L29/273 ,  A23V2002/00 ,  A61K8/73 ,  A61K31/721 ,  A61K47/36 ,  C08B37/0021 ,  C12P19/08 ,  C12P19/18 ,  C12Y204/01005

摘要： The invention relates to: a protein having dextran-saccharase activity and the sequence SEQ ID NO: 1 for an no acid sequence; a protein having dextran-saccharase activity and the sequence SEQ ID NO: 2 for an amino acid sequence; a complex containing a substrate and a protein with dextran-saccharase activity a method for synthesizing dextrans; and dextrans. The invention also relates to a method for synthesizing gluco-oligosaccharides and gluco-conjugates and to the resulting products.

公开(公告)号：US20170198324A1

公开(公告)日：2017-07-13

申请号：US15313321

申请日：2015-05-22

申请人： E. I. DU PONT DE NEMOURS AND COMPANY

发明人： Qiong Cheng ,  Robert Dicosimo ,  Arthur Ouwehand ,  Zheng You ,  Jian Ping Lai ,  Zheyong YU ,  Zhenghong ZHANG

IPC分类号： C12P19/18 ,  C12P19/08 ,  A61K31/721 ,  A61K8/73 ,  A61Q19/00 ,  A23L29/269 ,  A23L33/21 ,  A23L2/52 ,  A23C9/123 ,  A23L7/126 ,  A23L7/135 ,  A21D13/40 ,  A23L21/10 ,  A23G3/36 ,  A23G9/32 ,  C08B37/00

CPC分类号： C12P19/18 ,  A21D13/40 ,  A23C9/123 ,  A23G3/36 ,  A23G9/32 ,  A23L2/52 ,  A23L7/126 ,  A23L7/135 ,  A23L21/10 ,  A23L29/273 ,  A23L33/21 ,  A23V2002/00 ,  A61K8/73 ,  A61K31/716 ,  A61K31/721 ,  A61K2800/10 ,  A61K2800/85 ,  A61Q19/00 ,  C08B37/0009 ,  C08L5/00 ,  C08L2205/16 ,  C12P19/04 ,  C12P19/08 ,  C12Y204/01 ,  C12Y204/01005 ,  A23V2200/328 ,  A23V2250/5116 ,  A61K2300/00

摘要： An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.