公开(公告)号：US20020154315A1

公开(公告)日：2002-10-24

申请号：US10057040

申请日：2002-01-25

Inventor： Michael L. Myrick

IPC: G02F001/35 ,  G02F002/02 ,  G01J003/45 ,  G01B009/02

CPC classification number: G01J3/28 ,  G01J3/18 ,  G01J3/2803 ,  G01J3/36 ,  G01J3/502 ,  G01J3/51 ,  G01J3/524

Abstract: In optical filter systems and optical transmission systems, an optical filter compresses data into and/or derives data from a light signal. The filter way weight an incident light signal by wavelength over a predetermined wavelength range according to a predetermined function so that the filter performs the dot product of the light signal and the function.

Abstract translation: 在光学滤波器系统和光传输系统中，光学滤波器将数据压缩到光信号和/或从光信号中导出数据。 滤波器方式根据预定的功能，通过波长在预定波长范围上加权入射光信号，使得滤光器执行光信号和功能的积积。

公开(公告)号：US20040036884A1

公开(公告)日：2004-02-26

申请号：US10451096

申请日：2003-06-18

Inventor： Selim M. Unlu ,  Anna Swan ,  Bennett B. Goldberg ,  Stephen Ippolito ,  Lev Moiseev ,  Samuel Lipolf ,  Yunjie Tong

IPC: G01J003/45 ,  G01B009/02

CPC classification number: G01B9/02044 ,  G01B9/02023 ,  G01B9/04 ,  G01N21/4795 ,  G01N21/6458 ,  G01N2021/6417 ,  G01N2021/6441 ,  G02B21/22

Abstract: A method and apparatus for performing optical microscopy in one to three dimensions employs a spectral self-interference fluorescent microscopy technique that includes providing at least one fluorescent microscopy sample (220a, 220b), at least one objective lens (201), and a reflecting surface (204). The fluorescent sample is disposed between the objective lens and the reflecting surface, the distance (d1, d2) from the sample to the reflecting surface is several to several tens times an excitation wavelength. Excitation light (216) causes the fluorescent sample to emit light (214), at least a portion (214b) of which is reflected by the reflecting surface. The objective lens collects both the reflected light and the light emitted directly by the fluorescent sample (214a). The direct and reflected light interferences causing spectral oscillations in the emission spectrum. The periodicity and the peak wavelengths of the emission spectrum are then spectroscopically analyzed to determine the optical path length between the fluorescent sample and the reflecting surface.

Abstract translation: 用于在一到三维中执行光学显微镜的方法和装置采用光谱自干涉荧光显微镜技术，其包括提供至少一个荧光显微镜样品（220a，220b），至少一个物镜（201）和反射表面 （204）。 荧光试样配置在物镜与反射面之间，从样品到反射面的距离（d1，d2）为激发波长的数倍〜数十倍。 激发光（216）使得荧光样品发射光（214），其中至少一部分（214b）被反射表面反射。 物镜收集反射光和由荧光样品（214a）直接发射的光。 直接和反射的光干扰导致发射光谱中的光谱振荡。 然后对发射光谱的周期和峰值波长进行光谱分析，以确定荧光样品和反射表面之间的光程长度。

公开(公告)号：US20030224370A1

公开(公告)日：2003-12-04

申请号：US10158995

申请日：2002-05-31

Inventor： William Rassman ,  David Ralin ,  Feiming Zhou ,  Shubo Han

IPC: C12Q001/68 ,  G01N033/53 ,  G01J003/45 ,  G01B009/02

CPC classification number: G01N33/5306 ,  B01J2219/00581 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00702 ,  C12Q1/6837 ,  C40B70/00 ,  G01N21/552 ,  G01N2021/212 ,  C12Q2565/518 ,  C12Q2563/167

Abstract: A probe-target reaction is made more recognizable by the provision of a mass-enhancing and/or evanescent-field-perturbing amplifier element which reacts uniquely with and binds to the probe-target pair to provide increased mass. Where the probe-target pair is hybridized dsDNA, a suitable mass-enhancing amplifier is anti-double stranded DNA mouse IgM. In examples with sufficient sequence pairs in the probe-target combination, a sequence-specific minor-groove-binding polyamide can be used that carries biotin which can be amplified by streptavidin in a suitable carrier. In a preferred embodiment, a plurality of probes are immobilized at the sites of a microarray, each probe being specific to a different target. Optics utilizing total internal reflection are described for observing perturbation of the evanescent field.

Abstract translation: 通过提供质量增强和/或消逝场扰动放大器元件使得探针 - 靶反应更加可识别，该元件与探针 - 靶对独特地和结合起来以提供增加的质量。 当探针 - 靶对与dsDNA杂交时，合适的质量增强放大器是抗双链DNA小鼠IgM。 在探针 - 靶组合中具有足够序列对的实例中，可以使用携带生物素的序列特异性小槽结合聚酰胺，其可以通过链霉抗生物素蛋白在合适的载体中扩增。 在优选的实施方案中，多个探针固定在微阵列的位置，每个探针是针对不同靶标的。 描述了利用全内反射的光学来观察ev逝场的扰动。

公开(公告)号：US20040061862A1

公开(公告)日：2004-04-01

申请号：US10256794

申请日：2002-09-27

Inventor： Alan Ross ,  Edwin D. Tucker

IPC: G01B009/02 ,  G01J003/45

CPC classification number: G01J3/45 ,  G01B2290/35 ,  G02B7/004

Abstract: A linear positioning apparatus includes an intermediate portion having an axis, and first and second end portions mounted with flexure legs thereto. The flexure legs accommodate motion of the intermediate portion relative to the end portions along the axis, but inhibit motion of the intermediate portion relative to the end portions in directions not parallel to the axis. The apparatus can accommodate forces having off-axis components, and produce motion that comprises substantially no off-axis component. The apparatus is useful in, for example, optical systems where precise linear motion is required.

Abstract translation: 线性定位装置包括具有轴的中间部分，以及安装有弯曲腿的第一和第二端部。 弯曲腿容纳中间部分相对于沿着轴线的端部的运动，但是阻止中间部分相对于端部在不平行于轴线的方向上的运动。 该装置可以适应具有离轴部件的力，并且产生基本上不包括离轴部件的运动。 该装置在例如需要精确的线性运动的光学系统中是有用的。

公开(公告)号：US20030067606A1

公开(公告)日：2003-04-10

申请号：US10236870

申请日：2002-09-06

Applicant: Bruker Optik GmbH

Inventor： Arno Simon ,  Norbert Rapp

IPC: G01B009/02 ,  G01J003/45

CPC classification number: G01J3/453

Abstract: A method for taking a spatially resolved spectrum, in particular an infrared (IR) spectrum, of a sample by means of a Fourier-transform (FT)-spectrometer, is described wherein light emitted by a light source is fed to an interferometer, directed onto the sample and detected by an array-detector, wherein a movable reflector of the interferometer is displaced over a distance s and the array-detector is read out at a number n of predetermined discrete way points s1, . . . , sn of the distance s, respectively. When the movable reflector is displaced over the distance s, the array-detector is first read out at respective non-adjacent way points sd separated by at least one respective intermediate way point si, and that the movable reflector is displaced over the distance s at least twice, wherein the array-detector is read out at the way points si upon a second or further repeated displacement over the distance s.

Abstract translation: 描述了通过傅里叶变换（FT）光谱仪对样品进行空间分辨的光谱特别是红外（IR）光谱的方法，其中由光源发射的光被馈送到干涉仪，指向 通过阵列检测器检测，其中干涉仪的可移动反射器在一定距离s处移位，并且阵列检测器在n个预定离散方向点s1上被读出。 。 。 ，sn的距离s。 当可移动反射器移动距离s时，阵列检测器首先在由至少一个相应的中间路径点si分开的相应的非相邻路线点sd处被读出，并且可移动反射器在距离s处移动 最少两次，其中阵列检测器在距离s处的第二次或进一步重复位移时在点si处被读出。

公开(公告)号：US20040253751A1

公开(公告)日：2004-12-16

申请号：US10859846

申请日：2004-06-03

Inventor： Alex Salnik ,  Lena Nicolaides ,  Jon Opsal

IPC: H01L021/66 ,  G01R031/26 ,  G01J001/42 ,  G01J003/45 ,  G01B009/02

CPC classification number: G01R31/2621 ,  G01N21/171 ,  G01N21/1717

Abstract: A modulated reflectance measurement system includes two lasers for generating a probe beam and an intensity modulated pump beam. The probe beam is in the visible spectrum and the pump beam is in the ultra-violet spectrum. The pump and probe beams are joined into a collinear beam and focused by an objective lens onto a sample. Reflected energy returns through the objective and is redirected by a beam splitter to a detector. A lock-in amplifier converts the output of the detector to produce quadrature (Q) and in-phase (I) signals for analysis. A processor uses the Q and/or I signals to analyze the sample.

Abstract translation: 调制反射测量系统包括用于产生探测光束和强度调制泵浦光束的两个激光器。 探测光束处于可见光谱中，泵浦光束处于紫外光谱。 泵和探针光束被连接成共线光束并由物镜聚焦在样品上。 反射能量通过目标返回，并被分束器重定向到检测器。 锁定放大器转换检测器的输出以产生正交（Q）和同相（I）信号用于分析。 处理器使用Q和/或I信号来分析样本。

公开(公告)号：US20040100635A1

公开(公告)日：2004-05-27

申请号：US10338996

申请日：2003-01-09

Applicant: Intel Corporation

Inventor： Mark McDonald

IPC: G01J003/45 ,  G01B009/02

CPC classification number: G01J1/4257 ,  G01J3/0205 ,  G01J3/0256 ,  G01J3/0259 ,  G01J9/00

Abstract: A quasi-monochromatic light beam carrier for a particular telecommunication channel is likely to experience drift because of age, temperature, or other factors, and may cause the centroid wavelength of the carrier to shift. Temperature adjustments by wavelength lockers to compensate for drift on one channel may affect the performance of other channels. Embodiments of the present invention couple a quasi-monochromatic light beam through a substrate-based grating, diffract the light beam from the edge of the substrate to free space, and detect the light beam from free space at a position detector to determine the centroid wavelength based on a position of the light beam incident on the detector. The diffracted light beam may be reflected within the substrate a number of times prior to exiting the substrate towards the detector.

Abstract translation: 用于特定电信信道的准单色光束载波可能由于年龄，温度或其他因素而经历漂移，并且可能导致载波的质心波长偏移。 通过波长锁定器对一个通道上的漂移进行温度调节可能会影响其他通道的性能。 本发明的实施例将准单色光束通过基于基板的光栅耦合，将光束从基板的边缘衍射到自由空间，并且从位置检测器处的​​自由空间检测光束以确定质心波长 基于入射到检测器上的光束的位置。 在离开衬底朝向检测器之前，衍射光束可以在衬底内反射多次。

公开(公告)号：US20040023407A1

公开(公告)日：2004-02-05

申请号：US10624022

申请日：2003-07-21

Inventor： Hector L. Casal ,  Nazaneen Asker ,  Michael J. Seely ,  Linda L. Nero ,  Jean A. Baldwin

IPC: G01N021/62 ,  G01J003/45 ,  G01B009/02

CPC classification number: G01N21/3504 ,  G01N2021/3595 ,  Y10T436/11 ,  Y10T436/117497 ,  Y10T436/12

Abstract: The present invention is a method and an apparatus for identifying and quantifying components in an effluent stream from an ammoxidation reactor, the apparatus comprising a microprocessor; and a Fourier Transform infrared spectrometer having a sample cell through which may flow a portion of the effluent stream, an infrared source to emit infrared radiation and pass the infrared radiation through the effluent stream, an infrared detector to detect transmitted infrared radiation at the selected infrared wavelengths and to generate absorbance data due to absorbance of the infrared radiation by the components, wherein each of the components absorbs infrared radiation at one or more of the infrared wavelengths, and an output apparatus to provide the absorbance data to the microprocessor; wherein the microprocessor is programmed to identify and quantify each of the plurality of components based upon the absorbance data and calibration data, the calibration data being obtained from recovery run analyses and calibration analyses in the sample cell. The method may be applied to utilize the apparatus to provide real-time control of the operation of an ammoxidation reactor, based on the analytical results obtained by the FT-IR spectrometer and the calibration model developed therefor.

Abstract translation: 本发明是用于识别和定量来自氨氧化反应器的流出物流中的组分的方法和装置，该装置包括微处理器; 和傅里叶变换红外光谱仪，其具有样品池，通过该样品池可以流出一部分流出物流，红外源发射红外辐射并使红外辐射通过流出物流;红外检测器，用于检测所选红外线处的透射红外辐射 并且由于由所述部件的红外辐射的吸收而产生吸光度数据，其中每个部件吸收一个或多个红外波长的红外辐射，以及输出装置向微处理器提供吸光度数据; 其中所述微处理器被编程为基于所述吸光度数据和校准数据来识别和量化所述多个部件中的每一个，所述校准数据是从所述样品池中的恢复运行分析和校准分析获得的。 基于由FT-IR光谱仪获得的分析结果及其开发的校准模型，该方法可以应用于利用该装置来提供氨氧化反应器的操作的实时控制。

公开(公告)号：US20020005988A1

公开(公告)日：2002-01-17

申请号：US09859938

申请日：2001-05-17

Inventor： Christopher J. Duska ,  Jose Downes ,  Reich Watterson ,  Kevin McCallion

IPC: G01J003/45

CPC classification number: G02B6/29358 ,  G02B5/284 ,  G02B6/2938 ,  G02B6/4215

Abstract: An etalon comprising a first plate and a second plate positioned in parallel to one another and separated by a given distance, a single block spacer extending the given distance between the first plate and the second plate, and the single block spacer defining a chamber extending the given distance between the first plate and the second plate. A hermetically sealed etalon is also disclosed comprising a first plate and a second plate positioned in parallel to one another and separated by a given distance, a single block spacer extending the given distance between the first plate and the second plate, and the single block spacer defining a chamber extending the given distance between the first plate and the second plate, with the block spacer defining a first perimeter surrounding the chamber adjacent the first plate and a second perimeter surrounding the chamber adjacent the second plate, wherein the single block spacer surrounds the chamber along the given distance between the first plate and the second plate, and further wherein the single block spacer forms a first seal around the first perimeter adjacent the first plate and the single block spacer forms a second seal around the second perimeter adjacent the second plate, whereby to form the hermetically sealed etalon.

Abstract translation: 标准具包括第一板和彼此平行定位并且分开给定距离的第二板，在第一板和第二板之间延伸给定距离的单块垫片，并且单块垫片限定了延伸 给定距离在第一板和第二板之间。 还公开了密封的标准具，其包括彼此平行定位并分离给定距离的第一板和第二板，在第一板和第二板之间延伸给定距离的单块垫片，以及单块垫片 限定在所述第一板和所述第二板之间延伸给定距离的腔室，其中所述块隔板限定围绕所述腔室邻近所述第一板的第一周边和围绕所述腔室邻近所述第二板的第二周边，其中所述单块间隔件围绕 在第一板和第二板之间的给定距离处，并且进一步其中，单块隔离件围绕邻近第一板的第一周边形成第一密封，并且单块隔板围绕邻近第二板的第二周边形成第二密封 ，从而形成密封的标准具。

公开(公告)号：US20040070765A1

公开(公告)日：2004-04-15

申请号：US10470380

申请日：2003-07-28

Inventor： Kazunori Yamauchi

IPC: G01N033/48 ,  G01J003/45 ,  G01B009/02

CPC classification number: G01N21/255 ,  G01J3/26 ,  G01J3/36 ,  G01J3/51 ,  G01J3/513

Abstract: A light L from a light source 3 is transmitted through a sample cell S and is made incident into a spectroscopic portion 13. The spectroscopic portion 13 comprises interference filters 31-39 which transmit light components different in wavelengths and photodiodes 41-49 corresponding to the respective interference filters. Dielectric films to compose an interference filter have relatively satisfactory features to reflect a light component of wavelengths other than a light component of a wavelength to be transmitted. At each interference filter, an incident light is split into a light component to be transmitted and a light component to be reflected. By making the reflected light component into an incident light into a following-order interference filter, light components of nine wavelength types are detected.

Abstract translation: 来自光源3的光L通过样品池S透射并入射到分光部13中。分光部13包括干涉滤光器31-39，其透射波长不同的光成分和对应于光源3的光电二极管41-49。 各自的干扰滤波器。 构成干涉滤光器的介电膜具有相对令人满意的特征，以反射除了要透射的波长的光分量之外的波长的光分量。 在每个干涉滤光器处，入射光被分成待透射的光分量和被反射的光分量。 通过使入射光成为入射光成为后续的干涉滤光片，检测出9种波长类型的光成分。