公开(公告)号：US06729196B2

公开(公告)日：2004-05-04

申请号：US09775872

申请日：2001-02-01

申请人： Christopher L. Moler ,  Trent Wetherbee ,  Patrick Call ,  Charles J. Call ,  Vanessa M. Kenning

发明人： Christopher L. Moler ,  Trent Wetherbee ,  Patrick Call ,  Charles J. Call ,  Vanessa M. Kenning

IPC分类号： G01N3120

CPC分类号： B01D21/2455 ,  B01D45/08 ,  B01L3/5027 ,  G01N1/2208 ,  G01N1/2273 ,  G01N1/24 ,  G01N1/34 ,  G01N35/00009 ,  G01N2001/022 ,  G01N2001/2276 ,  G01N2001/245 ,  G01N2015/0288

摘要： A portable sampling unit capable of separating particulates, including biological organisms, from gaseous fluids such as air. A combined particle impact collector and fan is used to both move fluid through the sampling unit and to collect particulates. In one embodiment, the combined particle impact collector is a disposable unit that is removed and replaced with a fresh unit after each sampling period. The disposable unit is placed in a rinse station, where a liquid sample is extracted for later analysis. Alternatively, a disposable detection unit is incorporated in the sampling unit to provide real time detection of chemical toxins and/or biological pathogens. Preferably, the detector unit includes micro-fluidic channels so that a minimum amount of sample and test reagents are required. In another embodiment, the combined impact collector is integral to the sampling unit, rather than a separate disposable item.

摘要翻译： 一种便携式取样单元，能够将气体（如空气）的微粒分离出来，包括生物体。 组合的颗粒冲击收集器和风扇用于将流体移动通过取样单元并收集颗粒物。 在一个实施例中，组合的颗粒撞击收集器是在每个采样周期之后被移除并被新鲜单元替换的一次性单元。 将一次性单元放置在冲洗站中，其中提取液体样品用于后续分析。 或者，将一次性检测单元并入采样单元中以提供化学毒素和/或生物病原体的实时检测。 优选地，检测器单元包括微流体通道，使得需要最少量的样品和测试试剂。 在另一个实施例中，组合的冲击收集器与采样单元是一体的，而不是单独的一次性物品。

公开(公告)号：US06827906B1

公开(公告)日：2004-12-07

申请号：US09568456

申请日：2000-05-09

申请人： Torleif Ove Björnson ,  Laurence R. Shea

发明人： Torleif Ove Björnson ,  Laurence R. Shea

IPC分类号： G01N3120

CPC分类号： B01L3/50273 ,  B01L3/5025 ,  B01L3/502707 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0874 ,  B01L2300/0883 ,  B01L2300/0887 ,  B01L2400/0415 ,  B01L2400/0442 ,  B01L2400/0487 ,  B81B2201/058 ,  B81C1/00119 ,  B81C2201/019 ,  G01N27/44791

摘要： A continuous form microstructure array device is constructed as a flexible elongate film laminate containing a plurality of microstructures or arrays of microstructures arranged serially lengthwise along the laminate. The laminate can be continuously drawn from a supply roll or stack, advanced within an analytic device and, when analysis is complete, taken up in a storage roll or stack. The device provides for high throughput microfluidic processing.

摘要翻译： 连续形式的微结构阵列器件被构造为柔性细长膜层压体，其包含多个沿着层压体串联地纵向排列的微结构或微阵列阵列。 层压板可以从供应辊或堆叠中连续拉出，在分析装置内进行，并且当分析完成时，将其吸收在储存辊或堆中。 该设备提供高通量微流控处理。

公开(公告)号：US06806088B2

公开(公告)日：2004-10-19

申请号：US09827895

申请日：2001-04-09

申请人： John K. Howard

发明人： John K. Howard

IPC分类号： G01N3120

CPC分类号： C12Q1/6813 ,  G06F19/00 ,  G16H10/60 ,  Y10T436/111666 ,  Y10T436/115831 ,  C12Q2565/625

摘要： In a first exemplary embodiment, the present invention relates to an apparatus for performing an assay comprising a micro-system platform, a CD-ROM device and an information processor, where the CD-ROM device under control of the information processor is capable of reading and writing data to the micro-system platform. The micro-system platform comprises a first section for storing data in a continuous circular data band, which is disposed in an inner portion of the micro-system platform, and a second section including at least one assay, which is formed in an outer portion of the micro-system platform. During operation, the CD-ROM device retrieves and stores data related to the performance of the assay in the circular data band. The information processor is operative for controlling the CD-ROM device in accordance with the data retrieved from the circular data band, and for analyzing the results of the assay.

摘要翻译： 在第一示例性实施例中，本发明涉及一种用于执行测定的装置，其包括微系统平台，CD-ROM设备和信息处理器，其中信息处理器控制下的CD-ROM设备能够读取 并将数据写入微系统平台。 微系统平台包括第一部分，用于将数据存储在设置在微系统平台的内部的连续圆形数据带中，第二部分包括至少一个测定，第二部分形成在外部部分 的微系统平台。 在操作期间，CD-ROM设备在循环数据带中检索和存储与测定的性能相关的数据。 信息处理器可根据从循环数据带检索的数据来控制CD-ROM设备，并用于分析测定结果。

公开(公告)号：US06512982B2

公开(公告)日：2003-01-28

申请号：US09742667

申请日：2000-12-20

申请人： Ling Yang ,  Robert Falsetti

发明人： Ling Yang ,  Robert Falsetti

IPC分类号： G01N3120

CPC分类号： G01B3/44 ,  G01N33/20 ,  Y10S707/99943

摘要： A method and system for evaluating structural defects in metals is provided. In one embodiment, the method recognizes that the acceptability of a given defect is principally determined by the four basic parameters of operating temperature, operating stress, defect area, and defect shape. Ranges are established for each of these four basic parameters, and intermediate values within these ranges are selected to create a series of index value data sets. The method evaluates these index value data sets by calculating a life cycles estimate for each. Using statistical methods, the life cycles results are analyzed to determine the effect each of the four basic parameters has on the life of a component with a defect. Understanding the relationship between these four basic parameters and life cycles enables the method to provide an interpolation algorithm for finding the life cycles for any component having a defect.

公开(公告)号：US06267016B1

公开(公告)日：2001-07-31

申请号：US09265619

申请日：1999-03-10

申请人： Patrick T. Call ,  Vanessa M. Kenning ,  Charles Call ,  Joseph G. Birmingham ,  Donald J. Hammerstrom

发明人： Patrick T. Call ,  Vanessa M. Kenning ,  Charles Call ,  Joseph G. Birmingham ,  Donald J. Hammerstrom

IPC分类号： G01N3120

CPC分类号： G01N1/2273 ,  G01N1/2208 ,  G01N1/24 ,  G01N2001/245

摘要： A particle collector includes a combined impact collector and fan, which is usable for both drawing air or other gaseous fluid in which particulates are entrained into a cavity, and then separating the particulates from the gaseous fluid by providing a rotating surface that impacts the particulates. The particulates also impact on other surfaces within the cavity, including its inner surface, and are washed from these surfaces, which are wetted with water or other liquid injected into the cavity. The cavity is defined by a housing having an inlet port through which the air or other gaseous fluid is drawn. The combined impact collector and fan includes a plate on which a plurality of spaced-apart impeller vanes are disposed. The shape of the impeller vanes produces a centrifugal fan effect when they are rotated within the cavity. The water or other liquid is either continuously or intermittently injected into the cavity to wash the particulates from the impeller vanes and other surfaces on which they have impacted. The particulates are carried by the liquid through a threaded drain port, into a receiver that includes an exhaust port for the air or gaseous fluid. A pump recirculates the liquid from the receiver through a conduit that sprays the liquid into the cavity through the inlet port. The particulates collected in the receiver provide a specimen that can be analyzed to detect or identify the particulates that were entrained in the air or other gaseous fluid.

摘要翻译： 颗粒收集器包括组合的冲击收集器和风扇，其可用于将空气或其它气体流体抽吸到其中，其中颗粒被夹带到空腔中，然后通过提供影响颗粒的旋转表面将颗粒与气态流体分离。 颗粒也影响腔体内的其他表面，包括其内表面，并从这些表面洗涤，这些表面被注入空腔的水或其他液体润湿。 空腔由具有入口的壳体限定，空气或其它气态流体通过该入口吸入。 组合的冲击收集器和风扇包括其上设置有多个间隔开的叶轮叶片的板。 当叶轮叶片在空腔内旋转时，叶轮叶片的形状产生离心风扇效应。 水或其他液体连续地或间歇地注入空腔中以从叶轮叶片和其所撞击的其它表面洗涤微粒。 颗粒由液体通过螺纹排放口承载到包括用于空气或气体流体的排气口的接收器中。 泵将来自接收器的液体通过导管将液体通过入口喷射到空腔中。 收集在接收器中的颗粒提供可以分析以检测或识别被夹带在空气或其它气态流体中的颗粒的样品。