公开(公告)号：US20180030012A1

公开(公告)日：2018-02-01

申请号：US15550872

申请日：2016-02-03

申请人： Evonik Degussa GmbH

发明人： Jürgen Stock ,  Joao ANDRÉ ,  Sebastian IMM ,  Matthias PASCALY

IPC分类号： C07D301/12 ,  B01D61/02 ,  C07D303/02

CPC分类号： C07D301/12 ,  B01D61/027 ,  B01J23/34 ,  C07C11/04 ,  C07C11/06 ,  C07C21/067 ,  C07D303/02

摘要： In the method for the epoxidation of an olefin, the olefin is continuously reacted with hydrogen peroxide in a mixed reactor in the presence of a water soluble epoxidation catalyst, comprising a manganese complex, the reaction is carried out in a reaction mixture comprising an aqueous liquid phase and an organic liquid phase with mixing of the liquid phases, reaction mixture is continuously withdrawn from the mixed reactor and separated into a separated aqueous phase and a separated organic phase, and part of the separated aqueous phase is continuously recycled into the mixed reactor, with the combined hold-up time of aqueous phase in withdrawing, separating phases and recycling aqueous phase being kept at less than 15 minutes.

公开(公告)号：US09006465B2

公开(公告)日：2015-04-14

申请号：US13959198

申请日：2013-08-05

申请人： Shin-Etsu Chemical Co., Ltd.

发明人： Hideyoshi Yanagisawa

IPC分类号： C07D301/27 ,  C07D301/24 ,  C07D303/12 ,  C07D303/02 ,  C07F7/18 ,  C07D407/12 ,  C07C39/23 ,  C07F7/08

CPC分类号： C07F7/1876 ,  C07C39/23 ,  C07C2603/18 ,  C07D303/27 ,  C07D407/12 ,  C07F7/0838

摘要： An epoxy group-containing a fluorene compound has a methallyl group at the end thereof and is represented by the following general formula (1): wherein R represents a hydrogen atom or a methyl group. The compound gives a compound excellent in regioselectivity at the time of hydrosilylation with a Si—H containing organosilicon compound, with a less formed amount of an internally added β adduct, as compared with the conventionally known fluorene compound having an allyl group, so that heat resistance of the resulting organosilicon compound is expected to be improved whereby it is a useful compound.

摘要翻译： 含有环氧基的芴化合物的末端具有甲代烯丙基，并且由以下通式（1）表示：其中R表示氢原子或甲基。 该化合物在与含Si-H的有机硅化合物的氢化硅烷化时具有优异的区域选择性的化合物，内部添加的少量形成量。 与常规已知的具有烯丙基的芴化合物相比，预期所得有机硅化合物的耐热性得到改善，从而是有用的化合物。

公开(公告)号：US08575374B1

公开(公告)日：2013-11-05

申请号：US12908986

申请日：2010-10-21

申请人： Hugh C. DeLong ,  Paul C. Trulove ,  Robert A. Mantz ,  William M. Reichert ,  Jeremy Mandia

发明人： Hugh C. DeLong ,  Paul C. Trulove ,  Robert A. Mantz ,  William M. Reichert ,  Jeremy Mandia

IPC分类号： C07D303/02

CPC分类号： C07D233/60

摘要： The present invention describes the use of an ionic liquid acid catalyst for the hydrolysis of cellulose into reducing sugars and other degradation products. The use of an ionic liquid catalyst for the hydrolysis of cellulose provides a low volatility catalyst and eliminates the hazards associated with the handling of mineral acids. Conditions such as temperature, catalyst modification, and ionic liquid solvent control the production of reducing sugars and other products. The combination of using an ionic liquid as the solvent for cellulose and ionic liquid catalyst provides an unprecedented tunability of the reaction properties giving more control over the conversion process to produce dehydration products with higher yields depending on the desired feedstock.

摘要翻译： 本发明描述了离子液体酸催化剂用于将纤维素水解成还原糖和其它降解产物的用途。 使用离子液体催化剂水解纤维素提供低挥发性催化剂，并消除与无机酸的处理有关的危害。 条件如温度，催化剂改性和离子液体溶剂控制生产还原糖等产品。 使用离子液体作为纤维素和离子液体催化剂的溶剂的组合提供了前所未有的反应性质的可调性，从而更好地控制转化过程以根据所需原料以更高的产率生产脱水产物。

公开(公告)号：US08500900B2

公开(公告)日：2013-08-06

申请号：US13125246

申请日：2009-10-20

申请人： Tsunehito Sugiura ,  Taichi Kuroda

发明人： Tsunehito Sugiura ,  Taichi Kuroda

IPC分类号： C09D191/00 ,  C07D303/02 ,  B32B27/38 ,  C08L63/00 ,  C08L83/04

CPC分类号： D06M15/647 ,  C08L83/06 ,  D06M15/6433 ,  D21F1/30 ,  Y10T428/31511 ,  Y10T428/31663 ,  C08L83/00

摘要： A non-curable coating composition which uses a modified silicone having a functional group and can effectively prevent or reduce adhesion of sticky contamination substances to the surface of a substrate is provided. The non-curable coating composition contains a carboxy-modified silicone having carboxy-containing groups at side chains, and an epoxy/oxyalkylene-modified silicone having an epoxy-containing group and an oxyethylene-containing group at side chains, in a weight ratio ranging from 1:2 to 1:30.

摘要翻译： 提供了一种使用具有官能团的改性硅酮并可有效地防止或降低粘性污染物质粘合到基材表面的非固化涂料组合物。 不可固化涂料组合物含有在侧链具有含羧基的羧基改性的硅氧烷和在侧链具有含环氧基团和含氧化乙烯基团的环氧/氧化烯改性硅氧烷，重量比范围 从1:2到1:30。

公开(公告)号：US08450498B2

公开(公告)日：2013-05-28

申请号：US13107904

申请日：2011-05-14

申请人： Mark S. Paley

发明人： Mark S. Paley

IPC分类号： C07D235/04 ,  C07D233/00 ,  C07D303/02

CPC分类号： C08G59/26 ,  C07D405/14 ,  C08G59/10 ,  C08G59/3245 ,  C08G59/5033 ,  C08G73/024 ,  C08G73/0273 ,  C08G73/0616 ,  C08L79/02 ,  C08L79/04 ,  C09D163/00 ,  C09D179/02 ,  C09D179/04 ,  C09J163/00 ,  C09J179/02 ,  C09J179/04

摘要： Ionic liquid epoxide monomers capable of reacting with cross-linking agents to form polymers with high tensile and adhesive strengths. Ionic liquid epoxide monomers comprising at least one bis(glycidyl) N-substituted nitrogen heterocyclic cation are made from nitrogen heterocycles corresponding to the bis(glycidyl) N-substituted nitrogen heterocyclic cations by a method involving a non-nucleophilic anion, an alkali metal cation, epichlorohydrin, and a strong base.

摘要翻译： 能够与交联剂反应形成具有高拉伸强度和粘合强度的聚合物的离子液体环氧化物单体。 包含至少一种双（缩水甘油基）N-取代的氮杂环阳离子的离子液体环氧化物单体由对应于双（缩水甘油基）N-取代的氮杂环阳离子的氮杂环通过涉及非亲核阴离子，碱金属阳离子 ，表氯醇和强碱。

公开(公告)号：US08273853B2

公开(公告)日：2012-09-25

申请号：US12417809

申请日：2009-04-03

申请人： Paul Birnbrich ,  Hans-Josef Thomas ,  Giorgio Sabbadini ,  Ulrich Nagorny ,  Georg Bourscheidt

发明人： Paul Birnbrich ,  Hans-Josef Thomas ,  Giorgio Sabbadini ,  Ulrich Nagorny ,  Georg Bourscheidt

IPC分类号： C08G65/00 ,  C08G65/22 ,  C08G65/24 ,  C08G65/26 ,  C08G65/28 ,  C07D303/02 ,  C07D301/27 ,  C07D301/28

CPC分类号： C08G59/182 ,  C08G65/2612 ,  C08G65/331 ,  C08G2650/58 ,  C08J3/03 ,  C08J2363/00 ,  C08J2371/00

摘要： Disclosed is a process for the preparation of emulsifiers E1 which are obtained by (a) reacting a polyol with propylene oxide or a mixture of ethylene oxide and propylene oxide, to give an intermediate Z1, (b) reacting the intermediate Z1 with epichlorohydrin, forming an intermediate Z2, (c) reacting the intermediate Z2 with an adduct of ethylene oxide or a mixture of ethylene oxide and propylene oxide, with a C1-C22 monoalcohol, provided that on average at least one epoxide function of the intermediate Z2 is reacted and on average at least one epoxide function originating from the intermediate Z2 is retained. Compounds E1 are suitable as emulsifiers for preparing aqueous emulsions or dispersions of epoxy resins.

摘要翻译： 公开了一种制备乳化剂E1的方法，其通过（a）使多元醇与环氧丙烷或环氧乙烷和环氧丙烷的混合物反应获得，得到中间体Z1，（b）使中间体Z1与表氯醇反应，形成 中间体Z2，（c）使中间体Z2与环氧乙烷或环氧乙烷和环氧丙烷的混合物与C1-C22一元醇的加合物反应，条件是中间体Z2的平均至少一个环氧官能团反应， 平均来说，保留来自中间体Z2的至少一种环氧化物官能团。 化合物E1适合用作制备环氧树脂的水性乳液或分散体的乳化剂。

公开(公告)号：US20120035170A1

公开(公告)日：2012-02-09

申请号：US13214344

申请日：2011-08-22

申请人： José Maria Núñez ,  Antonius Adrianus Hendrikus Petrus Megens ,  Andrés Avelino Trabanco-Suárez

发明人： José Maria Núñez ,  Antonius Adrianus Hendrikus Petrus Megens ,  Andrés Avelino Trabanco-Suárez

IPC分类号： A61K31/343 ,  C07D307/93 ,  C07D337/14 ,  C07C43/192 ,  C07C49/567 ,  C07D495/04 ,  C07D495/14 ,  C07D303/02 ,  C07C35/52 ,  C07D333/80 ,  C07D493/04 ,  C07D405/06 ,  C07D405/12 ,  C07D413/12 ,  A61K31/38 ,  A61K31/407 ,  A61K31/496 ,  A61K31/5377 ,  A61P25/22 ,  A61P25/24 ,  A61P25/18 ,  A61P25/00 ,  A61P15/00 ,  A61P25/06 ,  A61P25/28 ,  A61P25/30 ,  A61P3/04 ,  C07D317/26

CPC分类号： C07D307/935 ,  C07D303/10 ,  C07D317/26 ,  C07D333/80 ,  C07D335/04 ,  C07D405/06 ,  C07D405/12 ,  C07D491/04 ,  C07D491/10 ,  C07D493/04 ,  C07D495/04 ,  C07D495/14

摘要： This invention concerns novel substituted unsaturated tetracyclic tetrahydrofuran derivatives with binding affinities towards serotonine receptors, in particular 5-HT2A and 5-HT2C receptors, and towards dopamine receptors, in particular dopamine D2 receptors and with norepinephrine reuptake inhibition properties, pharmaceutical compositions comprising the compounds according to the invention, the use thereof as a medicine, in particular for the prevention and/or treatment of a range of psychiatric and neurological disorders, in particular certain psychotic, cardiovascular and gastrokinetic disorders and processes for their production.The compounds according to the invention can be represented by general Formula (I) and comprises also the pharmaceutically acceptable acid or base addition salts thereof, the stereochemically isomeric forms thereof, the N-oxide form thereof and prodrugs thereof, wherein all substituents are defined as in claim 1.

摘要翻译： 本发明涉及对5-羟色胺受体，特别是5-HT2A和5-HT2C受体具有结合亲和性，对多巴胺受体，特别是多巴胺D2受体和去甲肾上腺素再摄取抑制性质的新型取代的不饱和四环四氢呋喃衍生物，包含根据 本发明作为药物的用途，特别是用于预防和/或治疗一系列精神病和神经障碍，特别是某些精神病，心血管和胃肠功能紊乱及其制备方法。 根据本发明的化合物可以由通式（I）表示，并且还包括其药学上可接受的酸或碱加成盐，其立体化学异构形式，其N-氧化物形式及其前药，其中所有取代基定义为 在权利要求1中。

公开(公告)号：US07956205B2

公开(公告)日：2011-06-07

申请号：US11634745

申请日：2006-12-05

申请人： Michael G. Denoux ,  Ritchie Tregre ,  Garrett Mineo

发明人： Michael G. Denoux ,  Ritchie Tregre ,  Garrett Mineo

IPC分类号： C07D301/32 ,  C07D301/36 ,  C07D303/02 ,  C07C51/43 ,  C11B3/00 ,  C11B7/00 ,  C11B13/00 ,  C09K15/32

CPC分类号： C07C57/12 ,  C08K3/32 ,  C08K5/526 ,  C11C1/08 ,  C11C3/006 ,  C11C3/12

摘要： Disclosed is a method for the reduction of residual peroxides in vegetable oils, preferably epoxidized vegetable oils using a phosphorous compound preferably alkyl/aryl substituted phosphite compounds or hypophosphorous acid and its derivatives.

摘要翻译： 公开了一种减少植物油中残留过氧化物的方法，优选使用磷化合物，优选烷基/芳基取代亚磷酸酯化合物或次磷酸及其衍生物的环氧化植物油。

公开(公告)号：US20100099790A1

公开(公告)日：2010-04-22

申请号：US12450905

申请日：2008-04-16

申请人： Takao Manabe ,  Makoto Seino ,  Shinya Mizuta

发明人： Takao Manabe ,  Makoto Seino ,  Shinya Mizuta

IPC分类号： C08L83/04 ,  C08G77/04 ,  C07D303/02 ,  C07F7/00

CPC分类号： C08G77/38 ,  C07F7/21 ,  C08F230/08 ,  C08G77/04 ,  C08G77/045 ,  C08G77/12 ,  C08G77/14 ,  C08G77/20 ,  C08G77/50 ,  C08K3/36 ,  C08K5/56 ,  C09D183/04 ,  G02B1/04 ,  G02B1/10 ,  C08L83/00

摘要： The present invention has its object to provide a liquid-form modified product of polyhedral polysiloxane which is excellent in moldability and transparency, and a composition produced using the modified product. In addition, the present invention can provide an easy-to-handle modified product and composition. The present invention provides a modified product of polyhedral polysiloxane which is obtainable by modifying a polyhedral polysiloxane compound (a) with a compound (b), and a composition containing the modified product. The polyhedral polysiloxane compound (a) has an alkenyl group and/or a hydrosilyl group, and the compound (b) has a hydrosilyl group and/or an alkenyl group each capable of hydrosilylation with the component (a).

摘要翻译： 本发明的目的是提供一种成型性和透明性优异的多面体聚硅氧烷的液态改性产物和使用该改性产物制备的组合物。 此外，本发明可以提供易于处理的改性产品和组合物。 本发明提供通过用化合物（b）改性多面体聚硅氧烷化合物（a）和含有该改性产物的组合物得到的多面体聚硅氧烷的改性产物。 多面体聚硅氧烷化合物（a）具有烯基和/或氢化甲硅烷基，化合物（b）具有能够与（a）成分氢化硅烷化的氢化硅烷基和/或烯基。

公开(公告)号：US07612123B2

公开(公告)日：2009-11-03

申请号：US11664503

申请日：2005-10-04

申请人： Hisao Kato ,  Yoji Horie ,  Hiroshi Sasaki

发明人： Hisao Kato ,  Yoji Horie ,  Hiroshi Sasaki

IPC分类号： C08G65/08 ,  C07D303/04 ,  C07D303/02

CPC分类号： C07D303/04 ,  C08G59/24 ,  C08G65/08 ,  G03F7/038

摘要： An object of the present invention is to provide a cyclohexene oxide compound that gives a cured resin having a low refractive index and excellent transparency, curability, mold release properties, and mechanical properties, and that can be used as a component of an actinic radiation curing composition and/or heat curing composition.The present invention is a cyclohexene oxide compound having a cyclohexyl group or a long-chain alkyl group, represented by Formula (1) below (in Formula (1), A denotes a cyclohexyl group, Formula (2) below, or an optionally branched alkyl group having 8 to 16 carbons) (in Formula (2), R1 denotes a hydrogen atom or an optionally branched alkyl group having 1 to 4 carbons and R2 denotes a hydrogen atom or an optionally branched alkyl group having 1 to 4 carbons).

摘要翻译： 本发明的目的在于提供一种环氧化烯化合物，其具有低折射率和优异的透明性，固化性，脱模性能和机械性能的固化树脂，并且可以用作光化辐射固化的组分 组合物和/或热固化组合物。 本发明是由下式（1）表示的具有环己基或长链烷基的环氧环己烷化合物（式（1）中，A表示环己基，下述式（2））或任意支链状 具有8〜16个碳原子的烷基）（式（2）中，R 1表示氢原子或碳原子数1〜4的任意支化烷基，R 2表示氢原子或可以具有碳原子数1〜4的烷基）。