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公开(公告)号:US12116458B2
公开(公告)日:2024-10-15
申请号:US17287978
申请日:2019-10-24
申请人: GenEdit, Inc.
发明人: Kunwoo Lee , Santanu Maity
CPC分类号: C08G69/10 , A61K47/595 , C08G69/48
摘要: Provided is a polymer comprising a structure of Formula 1 or Formula 3 as provided herein, as well as a method of making the same; a composition comprising the polymer and a nucleic acid and/or polypeptide; and a method of delivering a nucleic acid and/or polypeptide to a cell.
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公开(公告)号:US20240336734A1
公开(公告)日:2024-10-10
申请号:US18681351
申请日:2022-08-04
摘要: A synthetic mucin formed by performing a ring-opening polymerization of carbohydrate N-carboxyanhydride (NCA) followed by deprotection of at least one protecting group from the carbohydrate. The resulting synthetic mucin can be produced in large quantities and obviates many of the problems associated with using natural mucins obtained from biological sources.
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公开(公告)号:US20240293537A1
公开(公告)日:2024-09-05
申请号:US17800066
申请日:2021-11-17
发明人: Wenzhu YIN , Jinqiu ZHANG , Mingxu ZHOU , Yu LU
CPC分类号: A61K39/39 , A61K47/595 , A61K49/0043 , C08G69/48 , A61K2039/55511
摘要: An amphiphilic imiquimod-grafted lauryl γ-polyglutamate is prepared by adopting a method comprising the following steps: (1) dispersing γ-polyglutamic acid in an aprotic solvent in an anhydrous atmosphere, then adding a catalyst N,N-dimethylformamide, adding dropwise a chlorinating agent under stirring, and keep reaction of the mixture for 10-40 hours; (2) adding imiquimod, liposoluble alcohol and an acid-binding agent into the solution obtained in the step (1) after reaction, and reacting for 42-54 hours; and (3) after purification, obtaining an amphiphilic imiquimod-grafted lauryl γ-polyglutamate material.
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公开(公告)号:US20240218107A1
公开(公告)日:2024-07-04
申请号:US18556056
申请日:2022-04-22
申请人: ARKEMA FRANCE
发明人: Thomas PRENVEILLE , Florent ABGRALL
IPC分类号: C08G18/12 , B29C45/00 , B29K75/00 , B29K77/00 , C08G18/32 , C08G18/42 , C08G69/48 , C08L75/06 , C08L77/02 , C08L77/06 , C08L87/00
CPC分类号: C08G18/12 , B29C45/0001 , C08G18/3206 , C08G18/4238 , C08G69/48 , C08L75/06 , C08L77/02 , C08L77/06 , C08L87/005 , B29K2075/00 , B29K2077/00 , C08G2410/00 , C08L2205/03
摘要: A composition including at least one thermoplastic polyurethane and at least one polyamide comprising amine chain ends, wherein the polyamide is the reaction product of one or more monomers chosen from amino acids or aminocarboxylic acids, lactams and monomers resulting from the reaction between an aliphatic diamine and a dicarboxylic acid. Also, a composition obtained by the reaction of at least one thermoplastic polyurethane or thermoplastic polyurethane precursors and of at least one polyamide comprising amine chain ends, processes for preparing such compositions and articles made therefrom.
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公开(公告)号:US12024593B2
公开(公告)日:2024-07-02
申请号:US17692856
申请日:2022-03-11
申请人: Workers First LLC
CPC分类号: C08G69/48 , C08K3/22 , C08K5/057 , C08K2003/2206
摘要: A method of making an acid neutralizing polymer includes: a) preparing a first reaction mixture by blending of a polyamide material, a solid strongly basic material, and a halogenated-dimethylalkylamine; b) adding the first reaction mixture to a first compounding machine; c) reacting the first reaction mixture for a time and at a temperature sufficient to produce a first reaction product; d) preparing a second reaction mixture including the polyamide material; e) adding the second reaction mixture to a second compounding machine; f) reacting the second reaction mixture for a time and at a temperature sufficient to produce a second reaction product; g) preparing a third reaction mixture by blending the first reaction mixture and the second reaction mixture; h) adding the third reaction mixture to a third compounding machine; and i) reacting the third reaction mixture for a time and at a temperature sufficient to produce the acid neutralizing polymer.
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公开(公告)号:US20240204194A1
公开(公告)日:2024-06-20
申请号:US18287642
申请日:2022-04-22
发明人: Se Joo PARK , In Hwan HWANG , Ik Sang LEE
摘要: The present application relates to a polyamic acid composition, a binder resin composition for an electrode, an electrode active material composition comprising the binder resin composition, and an electrode comprising same, and provides a novel binder material which has excellent mechanical strength and excellent binding force by synthesizing polyamic acid and applying same as a silicone-based negative electrode binder.
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公开(公告)号:US11993714B2
公开(公告)日:2024-05-28
申请号:US16763567
申请日:2018-11-16
申请人: Arkema France
IPC分类号: C08L77/12 , C08F293/00 , C08G69/48
CPC分类号: C08L77/12 , C08F293/00 , C08G69/48
摘要: The invention relates to a copolymer containing rigid polyamide PA blocks and flexible blocks, characterized in that it includes at least one carboxylic acid chain end blocked with a polycarbodiimide, said copolymer according to the invention being in noncrosslinked linear form. The invention also relates to the use of a polycarbodiimide in a process for manufacturing a copolymer containing rigid polyamide PA blocks and flexible blocks, including at least one carboxylic acid chain end, for improving the extrudability of the copolymer, the drawability of the copolymer, the abrasion resistance, the tear strength and the durability of the copolymer, without increasing its dispersity.
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公开(公告)号:US11976169B2
公开(公告)日:2024-05-07
申请号:US17841095
申请日:2022-06-15
发明人: Nacu Hernandez , Mengguo Yan , Eric William Cochran , John Edward Matthiesen , Jean-Philippe Tessonnier
IPC分类号: C08G69/26 , C08G69/28 , C08G69/48 , C08G77/455 , C08G81/02
CPC分类号: C08G69/265 , C08G69/26 , C08G69/28 , C08G69/48 , C08G77/455 , C08G81/028
摘要: The present invention relates to a polymer comprising a repeating group having the structure of formula (I)
wherein R, R1, R2, R3, R4, X, and s are as described herein and salt thereof. Also disclosed is a process of synthesizing such polymers.-
公开(公告)号:US20230414765A1
公开(公告)日:2023-12-28
申请号:US18463711
申请日:2023-09-08
申请人: AGC INC. , THE UNIVERSITY OF TOKYO , NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
发明人: Mihoko HARA , Rintaro HARA , Kanjiro MIYATA , Mitsuru NAITO , Takanori YOKOTA
CPC分类号: A61K47/595 , C08G69/48 , A61K47/60
摘要: A polymer represented by the following formula (I):
wherein each symbol is as described in the specification, is useful as a drug carrier in effectively delivering a drug to a target site.-
公开(公告)号:US20230250252A1
公开(公告)日:2023-08-10
申请号:US18012988
申请日:2020-12-29
发明人: Huan CHANG , Nanbiao YE , Cheng LI , Wohua ZHOU , Xinxin LIU , Xiumei ZHU , Yujun SU , Lei TANG , Xianbo HUANG
CPC分类号: C08J11/08 , C08G69/48 , C08J2377/00
摘要: A recycling process for a polyamide waste material includes the following steps: adding a polyamide waste material into a mixed solvent to obtain a solution, heating the solution to 50° C. to a reflux temperature of the solution, conducting stirring for dissolution, and then conducting decolorization treatment and filtration to obtain a polyamide solution; and adding the polyamide solution into water, precipitating polyamide as a solid in deionized water, and conducting separation to obtain recycled polyamide. The mixed solvent includes, in parts by weight, 10-30 parts of phenol and 15-40 parts of toluene.
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