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    COMBINATION STEERABLE CATHETER AND SYSTEMS
    91.
    发明申请
    COMBINATION STEERABLE CATHETER AND SYSTEMS 审中-公开
    组合式可控导管和系统

    公开(公告)号：WO2018023044A1

    公开(公告)日：2018-02-01

    申请号：PCT/US2017/044460

    申请日：2017-07-28

    Applicant: MCNIVEN, Sean A. ,  VALENCIA, Francisco ,  VON OEPEN, Randolf

    Inventor： MCNIVEN, Sean A. ,  VALENCIA, Francisco ,  VON OEPEN, Randolf

    IPC: A61F2/24

    Abstract: A steerable catheter has a body with an outer surface and an inner surface defining a central lumen. The outer surface and inner surface define a wall of the body, which has a plurality of steering lumen and control lumen extending longitudinally therethrough. The body includes a body material. The steering lumen and control lumen have a control lumen lining and steering lumen lining, respectively, with a higher durometer than the body material. A steering wire is positioned within the steering lumen and a control wire is positioned within the control lumen.

    Abstract translation: 可操纵导管具有主体，该主体具有限定中央内腔的外表面和内表面。 外表面和内表面限定了本体的壁，该壁具有多个纵向延伸穿过其中的控制内腔和控制内腔。 身体包括身体材料。 转向腔和控制腔分别具有控制腔内衬和转向腔内衬，其硬度比主体材料高。 转向线位于转向腔内，控制线位于控制腔内。

    THREADED COIL
    92.
    发明申请
    THREADED COIL 审中-公开
    螺纹线圈

    公开(公告)号：WO2018023043A1

    公开(公告)日：2018-02-01

    申请号：PCT/US2017/044457

    申请日：2017-07-28

    Applicant: VON OEPEN, Randolf ,  MCNIVEN, Sean A.

    Inventor： VON OEPEN, Randolf ,  MCNIVEN, Sean A.

    IPC: A61F2/24 ,  A61B17/04

    Abstract: An intravascular delivery system includes a threaded coil. The threaded coil includes one or more wires coiled to form a spiral coil with at least one thread extending along a length of the threaded coil. The threaded coil is plastically deformable for delivery of the threaded coil to a target location in the body and is rotatable to longitudinally position an intravascular device at the target location.

    Abstract translation: 血管内输送系统包括螺纹线圈。 螺纹线圈包括一个或多个盘绕的线以形成螺旋线圈，其中至少一个螺纹沿着螺纹线圈的长度延伸。 螺纹线圈可塑性变形以将螺纹线圈输送到体内的目标位置，并且可旋转以将血管内装置纵向定位在目标位置。

    ELECTROCHEMICAL FORMATION OF FOIL-SHAPED STENT STRUTS
    93.
    发明申请
    ELECTROCHEMICAL FORMATION OF FOIL-SHAPED STENT STRUTS 审中-公开
    电子形成的形状的STENT STRUTS

    公开(公告)号：WO2012158470A3

    公开(公告)日：2013-02-28

    申请号：PCT/US2012037372

    申请日：2012-05-10

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS ,  VON OEPEN RANDOLF

    Inventor： VON OEPEN RANDOLF

    IPC: C25F3/16 ,  C25F7/00

    CPC classification number: C25F3/16 ,  A61F2/82 ,  C25F7/00 ,  C25F7/02

    Abstract: An apparatus and method for electrochemically treating the struts of an intravascular stent is disclosed. An intravascular stent is mounted in a chamber and is electrochemically treated in order to remove a portion of the stent struts in order to form an airfoil shape. The airfoil-shaped stent struts will reduce turbulent blood flow in the vasculature in which the stent is implanted thereby improving clinical outcome.

    Abstract translation: 公开了一种用于电化学处理血管内支架的支柱的装置和方法。 将血管内支架安装在腔室中并进行电化学处理以便去除支架支架的一部分以形成翼型形状。 翼型支架支架将减少植入支架植入的脉管系统中的湍流血流，从而改善临床结果。

    INTRALUMINAL SCAFFOLD SYSTEM AND USE THEREOF
    94.
    发明申请
    INTRALUMINAL SCAFFOLD SYSTEM AND USE THEREOF 审中-公开
    内部SCAFFOLD系统及其使用

    公开(公告)号：WO2012097311A3

    公开(公告)日：2012-10-04

    申请号：PCT/US2012021335

    申请日：2012-01-13

    Applicant: ABBOTT LAB ,  VON OEPEN RANDOLF ,  EHRENREICH KEVIN J

    Inventor： VON OEPEN RANDOLF ,  EHRENREICH KEVIN J

    IPC: A61F2/24 ,  A61F2/86

    CPC classification number: A61F2/2475 ,  A61F2/86 ,  A61F2210/009 ,  A61F2230/0058 ,  A61F2230/0076

    Abstract: Intraluminal scaffold assembly implantable in a body lumen of a patient to manipulate a valve of the lumen is provided. The intraluminal scaffold assembly includes an intraluminal scaffold (1100), an elongated core member (1200) coupled with the intraluminal scaffold having a length sufficient to traverse a valve in a body lumen with the intraluminal scaffold positioned proximate the valve. The intraluminal scaffold assembly can further include one or more additional intraluminal scaffolds, a weighted element (1201) or an active element that is coupled with the elongated core member. A system including a delivery system and the intraluminal scaffold assembly, as well as methods of delivering the intraluminal scaffold assembly and using the intraluminal scaffold assembly to manipulate a valve in a body lumen, is also provided.

    Abstract translation: 提供可植入患者的体腔中以操纵管腔的瓣膜的腔内支架组件。 管腔内支架组件包括管腔内支架（1100），与管腔内支架联接的细长芯构件（1200），其长度足以穿过体腔内的瓣膜，腔内支架位于瓣膜附近。 管腔内支架组件还可以包括一个或多个附加的管腔内支架，加权元件（1201）或与细长芯构件联接的有源元件。 还提供了包括递送系统和管腔内支架组件的系统，以及递送管腔内支架组件和使用管腔内支架组件来操纵体腔中的瓣膜的方法。

    EXPANDABLE MEMBER FORMED OF A FIBROUS MATRIX FOR INTRALUMINAL DRUG DELIVERY
    96.
    发明申请
    EXPANDABLE MEMBER FORMED OF A FIBROUS MATRIX FOR INTRALUMINAL DRUG DELIVERY 审中-公开
    用于腹腔内药物输送的纤维基质的可膨胀成员

    公开(公告)号：WO2010036697A1

    公开(公告)日：2010-04-01

    申请号：PCT/US2009/058012

    申请日：2009-09-23

    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. ,  EHRENREICH, Kevin, J. ,  NEWHAUSER, Richard, R. ,  VON OEPEN, Randolf ,  STANKUS, John

    Inventor： EHRENREICH, Kevin, J. ,  NEWHAUSER, Richard, R. ,  VON OEPEN, Randolf ,  STANKUS, John

    IPC: A61M25/00

    CPC classification number: A61M25/104 ,  A61L29/16 ,  A61L2300/606 ,  A61M25/10 ,  A61M25/1029 ,  A61M2025/1031 ,  A61M2025/105 ,  A61M2025/1075 ,  D01D5/0076

    Abstract: An intraluminal catheter device having an expandable member formed of a matrix of fiber elements with a therapeutic agent incorporated therein. The therapeutic agent can be coated on the fiber elements in a co-axial configuration. The fiber elements may also have a second coating including a protective substance surrounding the therapeutic agent. The matrix of fiber elements can be formed by electrospinning. A process of delivering a therapeutic agent to a target site includes providing an intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member having a therapeutic agent dispersed therein, and advancing the catheter device at a desired treatment site. Once at the desired treatment site, fluid is introduced into the inflation lumen to expand the expandable member from a first profile to a second profile, and the therapeutic agent is delivered to the desired treatment site.

    Abstract translation: 一种管腔内导管装置，其具有由其中结合有治疗剂的纤维元件基质形成的可扩张构件。 治疗剂可以以同轴构型涂覆在纤维元件上。 纤维元件还可以具有包含围绕治疗剂的保护性物质的第二涂层。 纤维元素的基质可以通过静电纺丝形成。 将治疗剂递送到靶位置的过程包括提供具有由纤维元件基质形成的可扩张构件的管腔内导管装置，所述可扩张构件具有分散在其中的治疗剂，并且将导管装置推进到期望的治​​疗部位。 一旦在所需的治疗部位，将流体引入充气腔，以将可膨胀构件从第一轮廓扩张到第二轮廓，并将治疗剂递送到所需的治疗部位。

    STIFFENING SUPPORT CATHETER
    98.
    发明申请
    STIFFENING SUPPORT CATHETER 审中-公开
    加强支撑导管

    公开(公告)号：WO2007124495A3

    公开(公告)日：2008-01-31

    申请号：PCT/US2007067237

    申请日：2007-04-23

    Applicant: ABBOTT LAB ,  VON OEPEN RANDOLF ,  COFFEY LORCAN ,  REITH THOMAS ,  NEWHAUSER RICHARD ,  YRIBARREN TRAVIS ,  GIANOTTI MARC ,  UIHLEIN BERNHARD ,  CLARK IAN J

    Inventor： VON OEPEN RANDOLF ,  COFFEY LORCAN ,  REITH THOMAS ,  NEWHAUSER RICHARD ,  YRIBARREN TRAVIS ,  GIANOTTI MARC ,  UIHLEIN BERNHARD ,  CLARK IAN J

    IPC: A61M25/00

    CPC classification number: A61M25/01 ,  A61B2017/003 ,  A61B2017/00336 ,  A61M25/0045 ,  A61M25/0053 ,  A61M25/008 ,  A61M2025/0183

    Abstract: A support catheter that can puncture a heart septum with a guidewire without buckling and that can access difficult to reach arteries such as carotid or renal arteries from the aorta under difficult circumstances is provided. The support catheter comprises a catheter body having a proximal end, a distal end, and an interior wall surface defining a first lumen extending from the proximal end toward the distal end. A second lumen is disposed between the interior wall surface and an outer surface of the catheter body. A plurality of stiffening members is disposed around the second lumen, the plurality of stiffening members being engageable to selectively stiffen the catheter body. In another configuration, the catheter further comprises a second plurality of stiffening members disposed between the first lumen and the second lumen.

    Abstract translation: 提供了一种支撑导管，其可以用导线刺穿心脏隔膜而没有屈曲，并且可以在困难的情况下进入难以到达主动脉的颈动脉或肾动脉的动脉。 支撑导管包括具有近端，远端和限定从近端朝向远端延伸的第一内腔的内壁表面的导管主体。 第二管腔设置在内壁表面和导管主体的外表面之间。 多个加强构件设置在第二内腔周围，多个加强构件可接合以选择性地加强导管主体。 在另一种构造中，导管还包括设置在第一腔和第二腔之间的第二多个加强构件。

    SYSTEMS TO FACILITATE WIRE AND DEVICE CROSSINGS OF OBSTRUCTIONS IN BODY LUMENS
    100.
    发明申请
    SYSTEMS TO FACILITATE WIRE AND DEVICE CROSSINGS OF OBSTRUCTIONS IN BODY LUMENS 审中-公开
    系统用于装配线路和装置的身体障碍的交叉

    公开(公告)号：WO2007124497A1

    公开(公告)日：2007-11-01

    申请号：PCT/US2007/067239

    申请日：2007-04-23

    Applicant: ABBOTT LABORATORIES ,  VON OEPEN, Randolf ,  MCCRYSTLE, Kelly, J.

    Inventor： VON OEPEN, Randolf ,  MCCRYSTLE, Kelly, J.

    IPC: A61B17/32 ,  A61N1/06

    CPC classification number: A61B17/2202 ,  A61B2017/22001 ,  A61B2017/22008 ,  A61B2017/22069 ,  A61B2017/22085 ,  A61B2017/22088 ,  A61B2017/22089 ,  A61B2018/263

    Abstract: In one of many possible embodiments, a method for treating an obstruction within a blood vessel includes applying a stimulus to a fluid near the obstruction to disrupt the obstruction. The stimulus may include applying a stimulus to the fluid near the obstruction to breach a proximal cap and applying a stimulus to dilate micro-channels formed within the obstruction. Such stimuli may include causing cavitation within one or more fluid near the device, expanding one or more fluid that is in contact with irregularities in the obstruction, and bombarding the obstruction with particles that undergo a rapid phase change.

    Abstract translation: 在许多可能的实施例之一中，用于治疗血管内的梗阻的方法包括对阻塞物附近的流体施加刺激以破坏阻塞。 刺激可以包括对阻塞物附近的流体施加刺激以破坏近端帽并施加刺激以扩张阻塞内形成的微通道。 这样的刺激可能包括在装置附近的一个或多个流体内造成气蚀，使与阻塞物中的不规则接触的一种或多种流体膨胀，并且用经历快速相变的颗粒轰击阻塞物。

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