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公开(公告)号：WO2018005599A3
公开(公告)日：2018-01-04
申请号：PCT/US2017/039661
申请日：2017-06-28
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： BRASHEARS, Mindy, M. , CAMPOS, David , NIGHTINGALE, Kendra , LONERAGAN, Guy , MILLER, Markus, F.
Abstract: The present invention provides a method for inhibiting the growth of pathogens in an animal feed comprising the steps of: contacting an animal feed with at least one lactic acid bacterium strain selected from the group consisting of Lactobacillus salivarius (L14, L28 and FS56), a mixture thereof; or a whey obtained from fermentation of the lactic acid bacterium strain, wherein the at least one lactic acid bacterium strain inhibits the growth of the pathogens, the nosocomial pathogens or the spoilage microorganisms in the pet food.
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22.发明申请
公开(公告)号：WO2017176816A3
公开(公告)日：2017-10-12
申请号：PCT/US2017/026023
申请日：2017-04-04
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： LI, Changzhi , PENG, Zhengyu
Abstract: Disclosed is a system and method for a 24-GHz phased array for indoor smart radar comprising at least 6 horizontally placed antenna elements as a vertically placed 5-element series-fed microstrip patch array. The beam of the phased array can be continuously steered on the H-plane to different directions through a novel vector control array. Each element can adjust the phase and amplitude of the corresponding element of the horizontally placed linear array. The phased array system of the present invention may be fabricated on a single printed circuit board (PCB), and PIN diodes are used to realize beam steering by modulating the decomposed received signal. In order to compensate for the loss of the vector control array and reduce the noise figure, six low noise amplifiers (LNAs) are also used in the array. The present invention has the ability to continuously steer the beam on the H-plane.
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23.发明申请INHIBITORS OF MCI-1 AS DRUGS TO OVERCOME RESISTANCE TO BRAF INHIBITORS AND MEK INHIBITORS 审中-公开MCI-1作为药物的抑制剂对BRAF抑制剂和MEK抑制剂的耐药性
公开(公告)号：WO2016200726A1
公开(公告)日：2016-12-15
申请号：PCT/US2016/036002
申请日：2016-06-06
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： SRIVASTAVA, Sanjay, K. , FOFARIA, Neel, M.
IPC: C07D211/16 , A61K31/445 , A61K38/16 , A61K39/395 , A61P35/00
CPC classification number: A61K31/4184 , A61K31/165 , A61K31/167 , A61K31/341 , A61K31/40 , A61K31/4025 , A61K31/405 , A61K31/4164 , A61K31/4178 , A61K31/4196 , A61K31/423 , A61K31/4245 , A61K31/433 , A61K31/437 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/445 , A61K31/4525 , A61K31/47 , A61K31/4709 , A61K31/495 , A61K31/496 , A61K31/4965 , A61K31/50 , A61K31/501 , A61K31/506 , A61K31/519 , A61K31/5375 , A61K31/5377 , A61K31/538 , A61K31/54 , A61K31/541 , A61K31/5415 , A61K45/06 , A61P35/00 , C07C233/87 , C07C237/00 , C07C237/52 , C07D207/337 , C07D209/08 , C07D209/42 , C07D211/34 , C07D215/48 , C07D217/06 , C07D233/60 , C07D235/10 , C07D235/12 , C07D235/16 , C07D235/28 , C07D249/12 , C07D263/34 , C07D265/36 , C07D279/02 , C07D295/108 , C07D307/54 , C07D317/60 , C07D401/06 , C07D403/06 , C07D403/14 , C07D405/06 , C07D409/14 , C07D413/06 , C07D417/12 , C07D487/04 , G01N33/5011 , G01N2333/4703 , A61K2300/00
Abstract: The present invention includes compositions and methods for inhibiting MCL-1, including novel inhibitors of MCL-1, and compositions and methods for treating a subject with cancer that is refractory to one or more MAPK pathway protein inhibitors.
Abstract translation: 本发明包括用于抑制MCL-1的组合物和方法，包括MCL-1的新型抑制剂，以及用于治疗患有对一种或多种MAPK通路蛋白抑制剂难治的癌症的受试者的组合物和方法。
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24.发明申请SEROTYPE DISCRIMINATION BIOMARKERS TO DISTINGUISH INFANTIS FROM HEIDELBERG AND NEWPORT FROM HADAR 审中-公开来自海德堡和新港的染色体污染生物标志物
公开(公告)号：WO2016160975A1
公开(公告)日：2016-10-06
申请号：PCT/US2016/024990
申请日：2016-03-30
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： BUGAREL, Marie , NIGHTINGALE, Kendra , LONERAGAN, Guy , BRASHEARS, Mindy
IPC: C12Q1/68
CPC classification number: C12Q1/689 , C12Q1/6806 , C12Q1/686 , C12Q2600/158 , C12Q2600/16 , Y02A50/451
Abstract: The present invention provides a set of oligonucleotides to screen for the presence of targeted Salmonella serotypes in enrichment or to characterize presumptive colonies. The set of oligonucleotides includes at least one set of primers and probe for the detection of Salmonella serotype selected from Newport, Heidelberg, Infantis, and Hadar and to discriminate between. These new markers can be used after the initial screening assay described herein as a discrimination assay to differentiate S. Heidelberg from S. Infantis and S. Hadar from S. Newport.
Abstract translation: 本发明提供一组寡核苷酸以筛选浓缩中目标沙门氏菌血清型的存在或表征推定的菌落。 该组寡核苷酸包括至少一组引物和探针，用于检测选自Newport，Heidelberg，Infantis和Hadar的沙门氏菌血清型，并鉴别。 这些新的标记物可以在本文描述的初始筛选测定之后用作鉴别测定法，以区分S.Heidelberg与S.Newport的S. Infantis和S.Hadar。
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公开(公告)号：WO2016010819A4
公开(公告)日：2016-01-21
申请号：PCT/US2015/039732
申请日：2015-07-09
Inventor： AL QAHTANI, Ghazi, D. , BERLOW, Noah, E. , SOLIMAN, Mohamed, Y.
IPC: E21B43/30
Abstract: A multilateral well placement methodology is provided for hydrocarbon reservoirs utilizing transshipment network optimization to best fit productivity conditions in the reservoir. Multilateral well trajectories are generated which ensure contact with hydrocarbon rich pockets in the reservoir. Different levels of branching for lateral wells are also permitted.
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Patent Agency Ranking
公开(公告)号：WO2016004394A1
公开(公告)日：2016-01-07
申请号：PCT/US2015/039119
申请日：2015-07-02
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： KIM, Jungkyu , LACERDA, Carla , LEE, Joohyung
CPC classification number: C12M23/16 , B01L3/502707 , B01L3/502738 , B01L2200/0647 , B01L2400/0481 , B01L2400/0487 , B01L2400/0638 , F16K99/0057
Abstract: Disclosed is a system for a biomimetic heart device simulating arterial flow and pulse properties thus allowing for a biomimetic microscale cardiac valve environment. The system's signaling and regulatory mechanisms linking mechano-sensing and cellular degenerative transformation provides details of force components and/or magnitudes leading heart valves to accelerated failure. The disclosed system supports a wide variety of scenarios for testing, diagnostics and drug delivery, and related products and services.
Abstract translation: 公开了一种用于模拟动脉血流和脉搏特性的仿生心脏装置的系统，从而允许仿生微量心脏瓣膜环境。 联系机械感知和细胞退化转化的系统的信号和调控机制提供了心脏瓣膜加速失败的力分量和/或幅度的细节。 所公开的系统支持用于测试，诊断和药物递送以及相关产品和服务的各种场景。
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公开(公告)号：WO2015191864A1
公开(公告)日：2015-12-17
申请号：PCT/US2015/035349
申请日：2015-06-11
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： SHENG, James, J.
CPC classification number: E21B43/168 , E21B43/164 , E21B43/255
Abstract: A process of producing liquid oil from shale gas condensate reservoirs and, more particularly, to increase liquid oil production by huff-n-puff in shale gas condensate reservoirs. The process includes performing a huff-n-puff gas injection mode and flowing the bottom-hole pressure lower than the dew point pressure.
Abstract translation: 一种从页岩气凝析油藏生产液态油的工艺，尤其是在页岩气凝析油藏中增加液体油的生产。 该方法包括进行吹气吹入气体喷射模式，并使底孔压力低于露点压力。
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28.发明申请OVERCOMING CHEMOTHERAPEUTIC AGENT RESISTANCE IN CANCER BY INHIBITING MCL-1 审中-公开通过抑制MCL-1抑制癌症的化疗药物耐药性
公开(公告)号：WO2015153657A2
公开(公告)日：2015-10-08
申请号：PCT/US2015/023666
申请日：2015-03-31
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： SRIVASTAVA, Sanjay, K. , FOFARIA, Neel
IPC: A61K39/395 , A61K38/16 , A61K31/52 , A61P35/00
CPC classification number: G01N33/57496 , A61K31/506 , A61K31/519
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29.发明申请
公开(公告)号：WO2015148785A1
公开(公告)日：2015-10-01
申请号：PCT/US2015/022704
申请日：2015-03-26
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： LONERAGAN, Guy , BRASHEARS, Mindy M. , NIGHTINGALE, Kendra , BUGAREL, Marie
CPC classification number: C12Q1/689 , C12Q2600/16 , G01N33/02 , Y02A50/451
Abstract: The present invention provides a set of oligonucleotides to screen for the presence of targeted Salmonella serotypes in an enrichment or to characterize presumptive colonies. The set of oligonucleotides includes at least one set of primers and probe for the detection of Salmonella serotype selected from Typhimurium, Enteritidis, Newport, Heidelberg, Infantis, Virchow and Hadar. The set of oligonucleotides may include up to 5 different primer sets and the corresponding probes.
Abstract translation: 本发明提供了一组寡核苷酸以筛选浓缩中目标沙门氏菌血清型的存在或表征推定的集落。 该组寡核苷酸包括至少一组引物和探针，用于检测选自鼠伤寒沙门氏菌，肠炎链球菌，纽波特，海德堡，婴儿，Virchow和Hadar的沙门氏菌血清型。 该组寡核苷酸可以包括多达5个不同的引物组和相应的探针。
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30.发明申请MICROWAVE-INDUCED LOCALIZED HEATING OF CARBON NANOTUBES FILLED POLYMER COMPOSITES FOR ENHANCED INTER-BEAD DIFFUSIVE BONDING OF FUSED FILAMENT FABRICATED PARTS 审中-公开微波诱导的碳纳米管的局部加热填充聚合物复合材料，用于增强融合的纤维织物的增强的内部珠粒扩散结合
公开(公告)号：WO2015147939A1
公开(公告)日：2015-10-01
申请号：PCT/US2014/072439
申请日：2014-12-26
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： SWEENEY, Charles, B. , GREEN, Micah, J. , SAED, Mohammad
CPC classification number: B29C67/007 , B29B15/14 , B29C35/0805 , B29C64/106 , B29C64/129 , B29C70/38 , B29C2035/0855 , B29K2105/167 , B33Y10/00 , B33Y30/00 , B33Y70/00 , B33Y80/00
Abstract: A microwave-induced heating of CNT filled (or coated) polymer composites for enhancing inter-bead diffusive bonding of fused filament fabricated parts. The technique incorporates microwave absorbing nanomaterials (carbon nanotubes (CNTs)) onto the surface or throughout the volume of 3D printer polymer filament to increase the inter-bead bond strength following a post microwave irradiation treatment and/or in-situ focused microwave beam during printing. The overall strength of the final 3D printed part will be dramatically increased and the isotropic mechanical properties of fused filament part will approach or exceed conventionally manufactured counterparts.
Abstract translation: CNT填充（或涂覆）聚合物复合材料的微波诱导加热，用于增强熔丝生产部件的珠间扩散接合。 该技术将微波吸收纳米材料（碳纳米管（CNTs））纳入到3D打印机聚合物长丝的表面或整个体积上，以在印刷后的微波辐射处理和/或原位聚焦微波束之后增加珠间粘合强度 。 最终3D印刷部件的总体强度将显着增加，并且熔丝部分的各向同性力学性能将接近或超过常规制造的对应物。
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