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    PERCUTANEOUS CARDIAC VALVE REPAIR WITH ADJUSTABLE ARTIFICIAL CHORDAE
    51.
    发明申请
    PERCUTANEOUS CARDIAC VALVE REPAIR WITH ADJUSTABLE ARTIFICIAL CHORDAE 审中-公开
    经皮心脏瓣膜修复与可调整的人造CHORDAE

    公开(公告)号：WO2007062054A2

    公开(公告)日：2007-05-31

    申请号：PCT/US2006/045087

    申请日：2006-11-21

    Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC. ,  DAVIDSON, Michael, J.

    Inventor： DAVIDSON, Michael, J.

    IPC: A61B17/138

    CPC classification number: A61B17/00234 ,  A61B17/0401 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0485 ,  A61B17/0625 ,  A61B17/0644 ,  A61B17/068 ,  A61B17/0682 ,  A61B2017/00243 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0417 ,  A61B2017/0441 ,  A61B2017/0443 ,  A61B2017/0454 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0472 ,  A61B2017/0496 ,  A61B2017/0649 ,  A61F2/2457 ,  A61F2/2487

    Abstract: The invention includes a novel method and system to achieve leaflet coaptation in a cardiac valve percutaneously by creation of neochordae to prolapsing valve segments. This technique is especially useful in cases of ruptured chordae, but may be utilized in any segment of prolapsing leaflet. The technique described herein has the additional advantage of being adjustable in the beating heart. This allows tailoring of leaflet coaptation height under various loading conditions using image- guidance, such as echocardiography. This offers an additional distinct advantage over conventional open-surgery placement of artificial chordae. In traditional open surgical valve repair, chord length must be estimated in the arrested heart and may or may not be correct once the patient is weaned from cardiopulmonary bypass. The technique described below also allows for placement of multiple artificial chordae, as dictated by the patient's pathophysiology.

    Abstract translation: 本发明包括一种新颖的方法和系统，用于通过创造新生物足以使瓣膜瓣脱垂来经皮地实现心脏瓣膜中的瓣叶适应。 这种技术在腱索破裂的情况下特别有用，但可用于脱垂小叶的任何部分。 本文描述的技术具有在跳动心脏中可调整的附加优点。 这允许使用图像引导（例如超声心动图）在各种负荷条件下调整小叶接合高度。 与传统的人工腱索开放式手术放置相比，这提供了更多的独特优势。 在传统的开放性手术瓣膜修复中，必须在停滞的心脏中估计弦长，并且一旦患者离开体外循环，可能会或可能不会正确。 下面描述的技术还允许放置多个人造腱索，如病人的病理生理学所指示。

    SUTURE DEVICE
    52.
    发明申请
    SUTURE DEVICE 审中-公开
    SUTURE设备

    公开(公告)号：WO2005112789A3

    公开(公告)日：2007-05-24

    申请号：PCT/IL2005000070

    申请日：2005-01-20

    Applicant: NEATSTITCH LTD ,  KEREN DVIR ,  LORE RAMI

    Inventor： KEREN DVIR ,  LORE RAMI

    IPC: A61B17/04 ,  A61B17/00 ,  A61B17/06

    CPC classification number: A61B17/0469 ,  A61B17/0057 ,  A61B17/0482 ,  A61B2017/00637 ,  A61B2017/00663 ,  A61B2017/047 ,  A61B2017/0472

    Abstract: A suture insertion device (120) includes a shaft (124), which is adapted to be inserted into a body cavity (154). First and second needles (160) hold respective first and second ends of a suture thread (122). First and second needle guides (130) are attached to the shaft and respectively hold the first and second needles. The needle guides have a first operative configuration in which the needle guides are held parallel to the axis of the shaft for insertion of the shaft into the body cavity and a second operative configuration in which the needle guides are deployed outward from the shaft within the body cavity so as to point the needles in a proximal direction. An ejector (164) is operative to eject the needles from the needle guides in the second operative configuration so as to cause the needles to penetrate tissue (156) adjoining the body cavity.

    Abstract translation: 缝合线插入装置（120）包括适于插入体腔（154）的轴（124）。 第一和第二针160保持缝合线（122）的相应的第一和第二端。 第一和第二针引导件（130）附接到轴并且分别保持第一和第二针。 针引导件具有第一操作构型，其中针引导件平行于轴的轴线保持，以将轴插入体腔中，以及第二操作构造，其中针引导件从身体内的轴向外展开 以使针沿近端方向指向。 喷射器（164）可操作以在第二操作构型中将针从针引导件中排出，以使针穿过邻近体腔的组织（156）。

    INSTRUMENT FOR EASING THE ANASTOMOSIS OF THE URETHRA IN LAPAROSCOPIC PROSTATECTOMY
    53.
    发明申请
    INSTRUMENT FOR EASING THE ANASTOMOSIS OF THE URETHRA IN LAPAROSCOPIC PROSTATECTOMY 审中-公开
    促进腹腔镜前列腺切除术中尿道输尿管吻合术的仪器

    公开(公告)号：WO2007043081A2

    公开(公告)日：2007-04-19

    申请号：PCT/IT2006/000702

    申请日：2006-10-03

    Applicant: ELENOR S.R.L. ,  FERRARI, Danilo

    Inventor： FERRARI, Danilo

    IPC: A61B17/00 ,  A61B17/11 ,  A61B17/04

    CPC classification number: A61B17/00234 ,  A61B17/0482 ,  A61B17/11 ,  A61B2017/00274 ,  A61B2017/0472 ,  A61B2017/1103 ,  A61B2018/00547

    Abstract: A surgical instrument for easing the anastomosis of the urethra in laparoscopic prostatectomy comprising a cannula (1), suitable for being inserted into the urethra from the penis until it reaches the resection point downstream of the prostate with its distal end (1a), and equipped with radial openings (5) close to the distal end, and a plurality of needle-shaped elements (7) housed in the cannula close to the distal end and suitable for projecting for a controlled extent through the radial openings to transfix the urethra anchoring it to the cannula. Means (8, 10, 20) are foreseen for moving the needle-shaped elements (7) from a position completely retracted in said cannula to a position projecting from it so that it is substantially inclined forwards. In this way, the surgeon can actuate said means from the proximal end of the cannula to make the needle-shaped elements project from the radial openings adjusting the amount that they project up to the transfixion of the urethra, for whereby the retraction of the remaining stump of urethra can be avoided.

    Abstract translation: 一种用于在腹腔镜前列腺切除术中缓解尿道吻合术的手术器械，其包括套管（1），适于从阴茎插入尿道直至其到达前列腺下游的切除点 远端（1a）并且配备有靠近远端的径向开口（5）;以及多个针状元件（7），所述多个针状元件（7）容纳在套管中，靠近远端并且适合于在受控程度上通过 径向开口穿透尿道将其固定到套管。 装置（8,10,20）可用于将针形元件（7）从完全缩回到所述插管中的位置移动到从其突出的位置，使其基本向前倾斜。 以这种方式，外科医生可以从套管的近端致动所述装置，以使得针形元件从径向开口突出，调节它们突出到尿道的横向的量，从而剩余的 可以避免尿道残端。

    METHOD OF IMPLANTING AN ANNULOPLASTY PROSTHESIS
    54.
    发明申请
    METHOD OF IMPLANTING AN ANNULOPLASTY PROSTHESIS 审中-公开
    植入ANNULOPLASTY PROSTHESIS的方法

    公开(公告)号：WO2007040999A1

    公开(公告)日：2007-04-12

    申请号：PCT/US2006/036734

    申请日：2006-09-20

    Applicant: MEDTRONIC, INC. ,  TABOR, Charles, P. ,  RYAN, Timothy, R. ,  DAVID, Tirone, E.

    Inventor： TABOR, Charles, P. ,  RYAN, Timothy, R. ,  DAVID, Tirone, E.

    IPC: A61F2/24 ,  A61B19/00

    CPC classification number: A61B17/0469 ,  A61B17/0467 ,  A61B17/0483 ,  A61B17/06061 ,  A61B90/94 ,  A61B2017/0472 ,  A61B2017/0496 ,  A61B2090/061 ,  A61F2/2448 ,  A61F2/2466

    Abstract: A simplified and more easily employed tool for holding an implantable annuloplasty prosthesis during passage of sutures through the prosthesis and for conveniently and efficiently releasing the prosthesis from the tool. Separation of the implantable prosthesis and the tool may be conveniently accomplished without requiring the use of a sharp instrument. Attachment between the prosthesis and its surgical carrying tool can be accomplished in a suture-less fashion. The tool includes a suture management device in some embodiments for selectively receiving and maintaining sutures otherwise securing the prosthesis to tissue. The tool comprises a handle (30) , a retainer (24) and a suture management device (28) .

    Abstract translation: 一种简化且更容易使用的工具，用于在通过假体的缝线通过期间保持可植入瓣膜成形术假体，并且用于方便地和有效地将假体从工具释放。 可以方便地实现可植入假体和工具的分离，而不需要使用尖锐的器械。 假体和其手术携带工具之间的附接可以无缝缝合的方式实现。 该工具在一些实施例中包括缝合线管理装置，用于选择性地接收和维持缝合线，否则将假体固定到组织。 该工具包括手柄（30），保持器（24）和缝线管理装置（28）。

    HANDLE FOR SUTURING APPARATUS
    56.
    发明申请
    HANDLE FOR SUTURING APPARATUS 审中-公开
    用于装备的手柄

    公开(公告)号：WO2006037039A2

    公开(公告)日：2006-04-06

    申请号：PCT/US2005034801

    申请日：2005-09-27

    Applicant: SUTURA INC ,  NOBLES ANTHONY A ,  DECKER STEVEN E ,  TRAN HUNG ,  BROSCH BENJAMIN G

    Inventor： NOBLES ANTHONY A ,  DECKER STEVEN E ,  TRAN HUNG ,  BROSCH BENJAMIN G

    IPC: A61B17/00 ,  A61B17/04

    CPC classification number: A61B17/0057 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0625 ,  A61B2017/00367 ,  A61B2017/00637 ,  A61B2017/00663 ,  A61B2017/00672 ,  A61B2017/0472 ,  A61B2017/2911 ,  A61B2017/2912

    Abstract: Methods and apparatus are provided for closing incisions within biological tissue. In one embodiment, a device and method are provided for suturing biological tissue, such as, for example, an organ or blood vessel. The suturing apparatus is particularly well suited for suturing an incision made in an artery, such as the femoral artery, following a catheterization procedure. The device eliminates the need to apply pressure to a patient's thigh for an extended period of time, and eliminates many of the complications and costs associated with the creation of a thrombus patch. In addition, the device comprises an improved handle portion which enables the physician to quickly and easily apply suture. The handle portion is very reliable and easy to manipulate. The suturing may be used in combination with existing catheter sheath introducers.

    Abstract translation: 提供了用于闭合生物组织内的切口的方法和装置。 在一个实施例中，提供了用于缝合生物组织的装置和方法，例如器官或血管。 缝合装置特别适用于在导管插入术后缝合在动脉（例如股动脉）上制成的切口。 该装置不需要长时间地向患者的大腿施加压力，并且消除了与创建血栓贴片相关的许多并发症和成本。 此外，该装置包括改进的手柄部分，其使医师能够快速且容易地应用缝线。 手柄部分非常可靠，易于操作。 缝合可以与现有的导管鞘引入器结合使用。

    MITRAL VALVE REPAIR SYSTEM AND METHOD FOR USE
    58.
    发明申请
    MITRAL VALVE REPAIR SYSTEM AND METHOD FOR USE 审中-公开
    麻醉阀维修系统及使用方法

    公开(公告)号：WO2004082523A2

    公开(公告)日：2004-09-30

    申请号：PCT/US2004007383

    申请日：2004-03-11

    Applicant: EDWARDS LIFESCIENCES CORP ,  ZARBATANY DAVID ,  TIEU TAI ,  PUNG PONAKA ,  VIDELL JOSEPH ,  PERRY KENNETH E ,  KRUMME JOHN ,  BUCHBINDER MAURICE

    Inventor： ZARBATANY DAVID ,  TIEU TAI ,  PUNG PONAKA ,  VIDELL JOSEPH ,  PERRY KENNETH E ,  KRUMME JOHN ,  BUCHBINDER MAURICE

    IPC: A61B17/00 ,  A61B17/04 ,  A61B17/22 ,  A61B17/30 ,  A61F2/24 ,  A61F

    CPC classification number: A61B17/0469 ,  A61B17/0467 ,  A61B17/0482 ,  A61B17/0487 ,  A61B2017/00243 ,  A61B2017/00371 ,  A61B2017/00783 ,  A61B2017/0445 ,  A61B2017/0451 ,  A61B2017/0464 ,  A61B2017/0472 ,  A61B2017/0488 ,  A61B2017/22052 ,  A61B2017/22069 ,  A61B2017/306 ,  A61F2/2442

    Abstract: The present invention is directed to various systems for repairing tissue within the heart of a patient. The mitral valve repair system of the present invention comprises a guide catheter having a proximal end, a distal end, and at least one internal lumen formed therein, a therapy catheter capable of applying a suture to the tissue, and a fastener catheter capable of attaching a fastener to the suture. The therapy catheter and the fastener catheter are capable of traversing the internal lumen of the guide catheter. In addition, the present invention discloses various methods for repairing tissue within the heart of the patient. In one embodiment, the method of repairing heart valve tissue includes advancing a guide catheter through a circulatory pathway to a location in the heart proximate to a heart valve, advancing a therapy catheter through the guide catheter to the heart valve, stabilizing a first leaflet with the therapy catheter, deploying a first suture into the stabilized first leaflet, disengaging the first leaflet from the therapy catheter while leaving the first suture attached thereto, stabilizing a second leaflet with the therapy catheter, deploying a second suture into the second leaflet, disengaging the second leaflet from the therapy catheter while leaving the second suture attached thereto, and joining the first and second leaflets by reducing the distance between the first and second sutures.

    Abstract translation: 本发明涉及用于修复患者心脏内的组织的各种系统。 本发明的二尖瓣修复系统包括具有近端，远端和形成在其中的至少一个内腔的引导导管，能够将缝合线施加到组织上的治疗导管，以及能够附接 紧固件到缝合线。 治疗导管和紧固导管能够穿过引导导管的内腔。 此外，本发明公开了用于修复患者心脏内的组织的各种方法。 在一个实施例中，修复心脏瓣膜组织的方法包括使引导导管通过循环路径前进到靠近心脏瓣膜的心脏中的位置，将治疗导管通过引导导管推进到心脏瓣膜，使第一传单与 所述治疗导管将第一缝合线部署到所述稳定化的第一小叶中，使所述第一传播带与所述治疗导管脱离接合，同时使所述第一缝合线附接到所述导管，使所述治疗导管稳定第二传播片，将第二缝合线部署到所述第二传单中， 第二传单，同时离开附接到其上的第二缝合线，并且通过减小第一和第二缝合线之间的距离来接合第一和第二小叶。

    SUTURE TEMPLATE FOR FACILITATING IMPLANTATION OF A PROSTHETIC HEART VALVE
    60.
    发明申请
    SUTURE TEMPLATE FOR FACILITATING IMPLANTATION OF A PROSTHETIC HEART VALVE 审中-公开
    用于促进前置心脏瓣膜植入的模型

    公开(公告)号：WO2004026184A1

    公开(公告)日：2004-04-01

    申请号：PCT/US2003/029764

    申请日：2003-09-18

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： ARGENTO, Claudio

    IPC: A61F2/24

    CPC classification number: A61F2/2427 ,  A61B17/0469 ,  A61B17/06061 ,  A61B2017/0472 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2250/0097

    Abstract: A suture template for facilitating implantation of a prosthetic valve includes a plurality of commissure portions (110) connected to a plurality of cusp portions (100) around an annulus. Each commissure portion has at least one notch (146) and each cusp portion can have an inwardly directed ledge (133) and at least one notch (138). In one embodiment, the notches open towards the bottom of the suture template. In another embodiment, the notches open towards the top of the suture template.

    Abstract translation: 用于促进人造瓣植入的缝合线模板包括连接到围绕环的多个尖部部分（100）的多个连合部（110）。 每个连合部分具有至少一个凹口（146），并且每个尖部部分可以具有向内指向的凸缘（133）和至少一个凹口（138）。 在一个实施例中，凹口向缝合线模板的底部开口。 在另一个实施例中，凹口向缝合线模板的顶部开口。

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