公开(公告)号：WO2012092086A1

公开(公告)日：2012-07-05

申请号：PCT/US2011/066678

申请日：2011-12-21

Applicant: ABBOTT LABORATORIES ,  LAI, Chron-Si ,  GARLEB, Keith A. ,  LASEKAN, John B. ,  DAVIS, Steven R. ,  CORDEL, Christopher T. ,  MERRITT, Dr. Russell J.

Inventor： LAI, Chron-Si ,  GARLEB, Keith A. ,  LASEKAN, John B. ,  DAVIS, Steven R. ,  CORDEL, Christopher T. ,  MERRITT, Dr. Russell J.

IPC: A23L1/30 ,  A23L1/29 ,  A23C9/152 ,  A61P1/00

CPC classification number: A61K31/05 ,  A23K20/158 ,  A23K50/30 ,  A23L33/12 ,  A23L33/30 ,  A23L33/40 ,  A23V2002/00 ,  A61K9/00 ,  A61K31/20

Abstract: Disclosed are nutritional formulations including predigested fats that can be administered to preterm infants, infants, toddlers, and children for improving tolerance, digestion, and absorption of nutrients and for reducing the incidence of necrotizing enterocolitis, colic, and short bowel syndrome. The predigested fats include fatty acid-containing monoglycerides and/or a fatty acid component.

Abstract translation: 公开了营养配方，其包括可以对早产儿，婴儿，幼儿和儿童施用的预消化脂肪，用于改善营养物质的耐受性，消化和吸收以及降低坏死性小肠结肠炎，绞痛和短肠综合征的发生率。 预先消化的脂肪包括含脂肪酸的单甘油酯和/或脂肪酸组分。

公开(公告)号：WO2012091917A1

公开(公告)日：2012-07-05

申请号：PCT/US2011/064605

申请日：2011-12-13

Applicant: ABBOTT LABORATORIES ,  MUNDELL, Alvin Horatio ,  RIBBLE, Barbara Ann

Inventor： MUNDELL, Alvin Horatio ,  RIBBLE, Barbara Ann

IPC: G01N21/35 ,  G01N21/94 ,  G01N21/90

CPC classification number: C12Q1/04 ,  B07C5/344 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/3581 ,  G01N21/9027 ,  G01N21/94

Abstract: The present disclosure provides a system for inspecting cases of packages having a substance subject to spoilage. An electromagnetic signal (e.g., a terahertz frequency signal) is directed to each package in a case, and an attenuated signal is received and sampled to generate a set of data points corresponding to each package. A peak within each set of data points is detected, and the data points are shifted with respect to time to align the detected peaks with a predetermined time. The sets of shifted data points are compared to a mathematical model to determine whether the substance in the package is spoiled, and a labeling system marks cases containing spoiled substance.

Abstract translation: 本公开提供了一种用于检查具有腐败物质的包装的情况的系统。 在一种情况下，电磁信号（例如，太赫兹频率信号）被引导到每个封装，并且衰减的信号被接收和采样以产生对应于每个封装的一组数据点。 检测每组数据点内的峰值，并且数据点相对于时间移动，以使检测到的峰值与预定时间对准。 将移位数据点的集合与数学模型进行比较，以确定包装中的物质是否损坏，并且标记系统标记包含被损坏物质的情况。

公开(公告)号：WO2012044505A1

公开(公告)日：2012-04-05

申请号：PCT/US2011/052533

申请日：2011-09-21

Applicant: ABBOTT LABORATORIES ,  PFOUTS, Mark D.

Inventor： PFOUTS, Mark D.

IPC: A61M5/142

CPC classification number: A61M5/14232 ,  A61M2205/12 ,  A61M2205/121

Abstract: An enteral feeding apparatus has a pump system including a bearing surface, a platen and a retainer mounted on the platen. The retainer has a first engagement member. A feeding set includes a cassette and a lumen attached to the cassette. The lumen has a peristalsis loop for extending around the bearing surface and the cassette has a second engagement member adapted for engagement with the first engagement member of the retainer to thereby secure the cassette to the pump system. The lumen is in tension when the peristalsis loop is extended around the bearing surface and the first and second engagement members are engaged. The second engagement member of the cassette is biased into engagement with the first engagement member of the retainer by the tension on the lumen.

Abstract translation: 肠内喂养装置具有泵系统，其包括支承面，压板和安装在压板上的保持架。 保持器具有第一接合构件。 送料装置包括一个盒子和一个连接在盒子上的内腔。 内腔具有用于在支承表面周围延伸的蠕动回路，并且盒具有适于与保持器的第一接合构件接合的第二接合构件，从而将盒固定到泵系统。 当蠕动回路围绕支承表面延伸并且第一和第二接合构件接合时，内腔处于张力。 盒的第二接合构件通过管腔上的张力被偏置成与保持器的第一接合构件接合。

公开(公告)号：WO2012044500A1

公开(公告)日：2012-04-05

申请号：PCT/US2011/052477

申请日：2011-09-21

Applicant: ABBOTT LABORATORIES ,  PFOUTS, Mark, D. ,  O'DONNELL, Philip, Anthony

Inventor： PFOUTS, Mark, D. ,  O'DONNELL, Philip, Anthony

IPC: B29C47/92 ,  A61M39/08 ,  B29C47/90

CPC classification number: B29C47/92 ,  A61M5/14232 ,  A61M39/08 ,  A61M2205/12 ,  A61M2207/00 ,  B29C47/0023 ,  B29C47/0066 ,  B29C2793/0027 ,  B29C2947/92123 ,  B29C2947/92142 ,  B29C2947/92152 ,  B29C2947/92266 ,  B29C2947/92333 ,  B29C2947/92447 ,  B29K2083/005 ,  B29L2023/007 ,  F04B43/08

Abstract: In a method and system for forming tubing to achieve at least one predetermined performance characteristic relating to the flow of a flowable material therethrough, a relationship is determined between at least one material characteristic of the tubing material, at least one operating parameter of the tube forming machine (310), and the at least one predetermined performance characteristic of the tubing. Based on this relationship, at least one operating parameter for operation of the tube forming machine (310) to achieve the at least one predetermined performance characteristic is determined. The at least one operating parameter is input into the tube forming machine (310) and the machine is operated to achieve the at least one predetermined performance characteristic.

Abstract translation: 在用于形成管道以实现与可流动材料通过其中的流动相关的至少一个预定性能特征的方法和系统中，在管材料的至少一种材料特性，至少一种管形成的操作参数之间确定关系 机器（310）和管道的至少一个预定的性能特征。 基于该关系，确定用于操作管成型机（310）以实现至少一个预定性能特征的至少一个操作参数。 至少一个操作参数被输入到管成型机（310）中，并且机器被操作以实现至少一个预定的性能特征。

公开(公告)号：WO2012024270A1

公开(公告)日：2012-02-23

申请号：PCT/US2011/047875

申请日：2011-08-16

Applicant: ABBOTT LABORATORIES ,  DAS, Tapas ,  PATEL, Guarav C. ,  SATHYA, Shreeram

Inventor： DAS, Tapas ,  PATEL, Guarav C. ,  SATHYA, Shreeram

IPC: A23L1/30 ,  A23L1/308 ,  A61K36/37 ,  A61K31/716 ,  A61P3/10

CPC classification number: A61K36/37 ,  A23L7/115 ,  A23L33/105 ,  A23L33/22 ,  A23V2002/00 ,  A61K31/716 ,  A61K36/899 ,  A61K36/8998 ,  A61K2300/00 ,  A23V2200/328 ,  A23V2250/1578 ,  A23V2250/1586 ,  A23V2250/21 ,  A23V2250/5034 ,  A23V2250/5086 ,  A23V2250/5114 ,  A23V2250/706 ,  A23V2250/708 ,  A23V2250/71 ,  A23V2250/032 ,  A23V2250/264 ,  A23V2250/5046

Abstract: Disclosed are nutritional compositions comprising a synergistic combination of cereal beta-glucans, including oat and or barley beta-glucans and Salacia extract, including Salacia oblonga, that are particularly useful in controlling the blood glucose response in a diabetic or other appropriate individual. The nutritional compositions are especially useful when formulated in powder form and then reconstituted with an appropriate liquid or sprinkled onto food during a meal, to thus control the postprandial blood glucose response to that meal.

Abstract translation: 公开了营养组合物，其包含谷类β-葡聚糖，包括燕麦和/或大麦β-葡聚糖和Salacia提取物（包括Longacia oblonga）的协同组合，其特别可用于控制糖尿病患者或其他合适个体中的血糖反应。 当以粉末形式配制时，营养组合物特别有用，然后用适当的液体重新配制或在进餐期间洒在食物上，从而控制餐后对血糖的反应。

公开(公告)号：WO2010141953A2

公开(公告)日：2010-12-09

申请号：PCT/US2010/037650

申请日：2010-06-07

Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION

Inventor： CHAN, Michael, K. ,  NAIR, Manoj, S. ,  LEE, Marianne, M.

IPC: C12N15/63 ,  C12N15/62 ,  C07K19/00 ,  C12N1/21 ,  C12R1/07

CPC classification number: A61K39/39 ,  A61K2039/55544 ,  C07K14/325 ,  C07K2319/00 ,  C07K2319/60 ,  C07K2319/735 ,  C12N15/62

Abstract: Embodiments exploit the ability of the organism Bacillus thuringiensis to produce regularly shaped micrometer-sized crystals of Cry insect protoxins. In various embodiments, these crystals are used as a platform to generate various compositions that are useful for numerous applications.

Abstract translation: 实施例利用生物苏云金芽孢杆菌生产规则形状的微米尺寸的Cry昆虫原毒素晶体的能力。 在各种实施方案中，这些晶体用作平台以产生可用于许多应用的各种组合物。

公开(公告)号：WO2017151739A1

公开(公告)日：2017-09-08

申请号：PCT/US2017/020153

申请日：2017-03-01

Applicant: ABBOTT LABORATORIES

Inventor： PAULUS, Kevin ,  MCBROOM, Jeremy

IPC: B65D51/24

Abstract: A container (100) for scoopable material including a container body (102) defining a reservoir to hold the scoopable material, a collar (106) attached to the container body, a lid (108) hingedly attached to the collar, and a leveler(114) extending from the underside of the lid.

Abstract translation: 一种用于可铲取材料的容器（100），所述容器（100）包括限定用于容纳所述可铲取材料的储存器的容器主体（102），连接到所述容器主体的颈圈（106），铰接地连接 到领子，以及从盖子下侧延伸的平整器（114）。

公开(公告)号：WO2017117398A1

公开(公告)日：2017-07-06

申请号：PCT/US2016/069228

申请日：2016-12-29

Applicant: ABBOTT LABORATORIES

Inventor： LOGHAVI, Laleh ,  KONUKLAR, Gul

IPC: A23L33/18 ,  A23J3/30 ,  A23J3/26 ,  A23J3/08 ,  A23J3/14

CPC classification number: C12Y304/00 ,  A23J3/08 ,  A23J3/14 ,  A23J3/26 ,  A23J3/30 ,  A23L33/18 ,  A23V2250/55 ,  C12P21/06

Abstract: A method of preparing a protein hydrolysate using extrusion technology is provided. An intact protein source and a protease component are added to an extruder and mixed therein to form a slurry including a protein hydrolysate having a degree of hydrolysis of 5% to 30%. The slurry has a total protein content of at least 30% based on the weight of solids in the slurry. A protein hydrolysate accordingly produced is also claimed.

Abstract translation: 提供了使用挤出技术制备蛋白质水解产物的方法。 将完整的蛋白质源和蛋白酶组分加入到挤出机中并在其中混合以形成包含水解度为5％至30％的蛋白质水解产物的浆液。 基于浆料中的固体重量，浆料具有至少30％的总蛋白质含量。 还要求保护相应产生的蛋白质水解产物。

公开(公告)号：WO2016086157A1

公开(公告)日：2016-06-02

申请号：PCT/US2015/062721

申请日：2015-11-25

Applicant: ABBOTT LABORATORIES

Inventor： ALBRECHT, Daniel ,  ENGLE, Mark

IPC: A61K31/702 ,  A61P25/28 ,  A23L33/00 ,  A23L33/10 ,  A23L33/115 ,  A23L33/12 ,  A23L33/13 ,  A23L33/15 ,  A23L33/21

CPC classification number: A23L33/40 ,  A23L33/10 ,  A23L33/115 ,  A23L33/12 ,  A23L33/13 ,  A23L33/15 ,  A23L33/17 ,  A23L33/28 ,  A23L33/30 ,  A23V2002/00 ,  A61K9/0095 ,  A61K31/047 ,  A61K31/07 ,  A61K31/202 ,  A61K31/355 ,  A61K31/702 ,  A61K31/708 ,  A61K2300/00

Abstract: Infant formulas that include at least one human milk oligosaccharide selected from 2'-fucosyllactose (2'-FL) and lacto-N-neotetraose (LNnT), polyunsaturated fatty acids (PUFAs) docosahexaenoic acid (DHA) and arachidonic acid (AA), where the AA and DHA are present in an n-6/n-3 ratio of between 1 and 1.8, at least 30 mg/L of nucleotides, where the nucleotides include inosine monophosphate, and at least 30 µg/L of lutein are disclosed. Also provided are methods of use of the infant formulas for improving at least one of cognition, learning, and memory in an infant. The methods include administering the infant formulas to an infant.

Abstract translation: 包含至少一种选自2'-岩藻糖基乳糖（2'-FL）和乳-N-新四糖（LNnT），多不饱和脂肪酸（PUFA）二十二碳六烯酸（DHA）和花生四烯酸（AA））的人乳寡糖的婴儿配方， 其中AA和DHA以1至1.8之间的n-6 / n-3比率存在，至少30mg / L的核苷酸，其中核苷酸包括肌苷单磷酸酯和至少30μg/ L的叶黄素 。 还提供了使用婴儿配方来改善婴儿的认知，学习和记忆中的至少一种的方法。 所述方法包括向婴儿施用婴儿配方奶粉。

公开(公告)号：WO2016086151A1

公开(公告)日：2016-06-02

申请号：PCT/US2015/062712

申请日：2015-11-25

Applicant: ABBOTT LABORATORIES

Inventor： ALBRECHT, Daniel ,  ENGLE, Mark

IPC: A61K31/702 ,  A61P25/28 ,  A23L33/15 ,  A23L33/135 ,  A23L33/21 ,  A23L33/00 ,  A23L33/10

CPC classification number: A61K35/747 ,  A23L33/10 ,  A23L33/135 ,  A23L33/15 ,  A23L33/28 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/355 ,  A61K31/702 ,  A61K31/7024 ,  A61K35/745 ,  A23V2200/3204 ,  A23V2200/322 ,  A23V2250/712 ,  A61K2300/00

Abstract: Infant formulas that include a combination of RRR-alpha-tocopherol, 2'-fucosyllactose, and at least one probiotic from the Lactobacillus or the Bifidobacterium genera are disclosed. Also provided are methods of use of the infant formulas for improving at least one of cognition, learning, and memory in an infant. The methods include administering the infant formulas to an infant.

Abstract translation: 公开了包括来自乳杆菌属或双歧杆菌属的RRR-α-生育酚，2'-岩藻糖基乳糖和至少一种益生菌的组合的婴儿配方。 还提供了使用婴儿配方来改善婴儿的认知，学习和记忆中的至少一种的方法。 所述方法包括向婴儿施用婴儿配方奶粉。