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公开(公告)号：WO2012052405A2
公开(公告)日：2012-04-26
申请号：PCT/EP2011/068116
申请日：2011-10-17
Applicant: LABORATORIOS MIRET, S.A. , ROCABAYERA BONVILA, Xavier , SEGUER BONAVENTURA, Joan , RODRIGUEZ MARTINEZ, Francisco Javier , PIERA EROLES, Eva
Inventor： ROCABAYERA BONVILA, Xavier , SEGUER BONAVENTURA, Joan , RODRIGUEZ MARTINEZ, Francisco Javier , PIERA EROLES, Eva
IPC: C07C231/24 , B01J2/00 , B02C2/00
CPC classification number: C07C277/00 , C07C279/14
Abstract: The invention relates to a method of the preparation of a cationic surfactant, derived from the condensation of fatty acids and esterified dibasic amino acids, having the formula (I): having a mean particle diameter of less than 300 μm; by preparing the cationic surfactant with a remaining content of water less than 5% by weight in a first step; and milling this dried material in the second step.
Abstract translation: 本发明涉及一种制备阳离子表面活性剂的方法，该阳离子表面活性剂衍生自具有式（I）的脂肪酸和酯化的二元氨基酸的缩合物：平均粒径小于300μm; 通过在第一步中制备剩余含量小于5重量％的阳离子表面活性剂; 并在第二步中研磨该干燥物料。
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公开(公告)号：WO2010136405A1
公开(公告)日：2010-12-02
申请号：PCT/EP2010/057059
申请日：2010-05-21
Applicant: LABORATORIOS MIRET, S.A. , ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , CARPINTERO CORDERO, Eloy , PIERA EROLES, Eva
Inventor： ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , CARPINTERO CORDERO, Eloy , PIERA EROLES, Eva
IPC: A23B4/20 , A23B4/30 , A23B5/12 , A23B5/20 , A23B7/158 , A23B7/16 , A23B9/26 , A23B9/32 , A23L3/3454 , A23L3/3526 , A23L3/3589
CPC classification number: A23L3/3526 , A23B4/10 , A23B4/20 , A23B4/30 , A23L3/3454 , A23L3/3589
Abstract: The invention is a method for the treatment of food products, wherein the food product is cut in slices or in cubes, and the slices or cubes are treated with an antimicrobial solution in the form of a cloud of droplets, characterized in that the treatment with the antimicrobial solution is conducted during the cutting of the slices or the cubes. The invention is also a cutting device for conducting the method of the invention. This cutting device contains at least one nozzle or system of spray dosage for the simultaneous treatment of the slices of the food product and the cutting blade.
Abstract translation: 本发明是用于处理食品的方法，其中食品以切片或立方体切割，切片或立方体用微滴形式的抗微生物溶液处理，其特征在于用 抗微生物溶液在切片或立方体时进行。 本发明也是用于实施本发明的方法的切割装置。 该切割装置包含用于同时处理食品和切割刀片的至少一个喷嘴或喷雾剂系统。
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公开(公告)号：WO2010000744A3
公开(公告)日：2010-01-07
申请号：PCT/EP2009/058197
申请日：2009-06-30
Applicant: LABORATORIOS MIRET, S.A. , ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , SEGRET PONS, Roger , PIERA EROLES, Eva
Inventor： ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , SEGRET PONS, Roger , PIERA EROLES, Eva
IPC: A01N37/46 , A01N43/50 , A23B4/20 , A61L2/00 , A61L2/16 , A61L12/14 , C11D3/00 , A01P3/00 , A01P15/00
Abstract: Cationic surfactants derived from the condensation of fatty acids and esterified dibasic amino acids, such as from lauric acid and arginine, in particular the ethyl ester of the laurarnide of the arginine monohydrochloride (LAE), may be used for the treatment of objects which are infected with spores. The spores may originate from bacteria or fungi.
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公开(公告)号：WO2010000744A2
公开(公告)日：2010-01-07
申请号：PCT/EP2009058197
申请日：2009-06-30
Applicant: MIRET LAB , ROCABAYERA BONVILA XAVIER , FIGUERAS ROCA SERGI , SEGRET PONS ROGER , PIERA EROLES EVA
CPC classification number: A01N47/44 , A01N37/46 , A01N43/50 , A23L3/3463 , A23L3/3499 , A23L3/3517 , A23L3/3526 , A61L2/18 , C11D1/10 , C11D3/48
Abstract: Cationic surfactants derived from the condensation of fatty acids and esterified dibasic amino acids, such as from lauric acid and arginine, in particular the ethyl ester of the laurarnide of the arginine monohydrochloride (LAE), may be used for the treatment of objects which are infected with spores. The spores may originate from bacteria or fungi.
Abstract translation: 衍生自脂肪酸和酯化二元氨基酸如月桂酸和精氨酸，特别是精氨酸一盐酸盐（LAE）的月桂酸酯的乙酯的阳离子表面活性剂可用于治疗被感染的物体 与孢子。 孢子可能来源于细菌或真菌。
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公开(公告)号：WO2009033508A3
公开(公告)日：2009-12-10
申请号：PCT/EP2007060598
申请日：2007-10-05
Applicant: MIRET LAB , ROCABAYERA BONVILA XAVIER , FIGUERAS ROCA SERGI , SEGRET PONS ROGER , PIERA EROLES EVA
CPC classification number: A23B4/22 , A01N43/90 , A23B4/20 , A23C19/11 , A23L3/3463 , A23L3/34635 , A01N2300/00
Abstract: A solid composition comprising a cationic surfactant, such as the ethyl ester of the lauramide of the arginine monohydrochloride (LAE) and a polyene fungicide such as natamycin is provided. The solid composition is the basis for providing solutions of natamycin of increased concentration. The solid composition may be used for providing a dispersion of natamycin in a suitable liquid, such as tap water or an organic solvent. The dispersion may be further diluted with water. This leads to a solution of natamycin in water. The combination of the cationic surfactant and the polyene fungicide displays a biological effect which is stronger than the effect of each of the two components alone.
Abstract translation: 提供了包含阳离子表面活性剂，例如精氨酸一盐酸盐（LAE）的月桂酰胺的乙酯和多奈杀真菌剂如游霉素的固体组合物。 固体组合物是提供增加浓度的那他霉素溶液的基础。 固体组合物可用于提供游霉素在合适的液体如自来水或有机溶剂中的分散体。 分散体可以进一步用水稀释。 这导致游霉素在水中的溶液。 阳离子表面活性剂和多烯杀真菌剂的组合显示比单独的两种组分中的每一种的效果更强的生物效应。
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Patent Agency Ranking
公开(公告)号：WO2012052405A3
公开(公告)日：2012-08-02
申请号：PCT/EP2011068116
申请日：2011-10-17
Applicant: MIRET LAB , ROCABAYERA BONVILA XAVIER , SEGUER BONAVENTURA JOAN , RODRIGUEZ MARTINEZ FRANCISCO JAVIER , PIERA EROLES EVA
Inventor： ROCABAYERA BONVILA XAVIER , SEGUER BONAVENTURA JOAN , RODRIGUEZ MARTINEZ FRANCISCO JAVIER , PIERA EROLES EVA
IPC: C07C231/24 , B01J2/00 , B02C2/00
CPC classification number: C07C277/00 , C07C279/14
Abstract: The invention relates to a method of the preparation of a cationic surfactant, derived from the condensation of fatty acids and esterified dibasic amino acids, having the formula (I): having a mean particle diameter of less than 300 µm; by preparing the cationic surfactant with a remaining content of water less than 5% by weight in a first step; and milling this dried material in the second step.
Abstract translation: 本发明涉及制备由脂肪酸和酯化的二元氨基酸缩合得到的阳离子表面活性剂的方法，其具有式（I）：平均粒径小于300μm; 通过在第一步骤中制备剩余水含量小于5重量％的阳离子表面活性剂; 并在第二步中研磨该干燥材料。
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7.发明申请
公开(公告)号：WO2008095534A1
公开(公告)日：2008-08-14
申请号：PCT/EP2007/051168
申请日：2007-02-07
Applicant: LABORATORIOS MIRET, S.A. , ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , SEGRET PONS, Roger , PIERA EROLES, Eva
Inventor： ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , SEGRET PONS, Roger , PIERA EROLES, Eva
IPC: A23L2/44 , A23L3/3526 , A61K8/44 , A61Q11/00 , A23L1/226 , A23L1/227 , A23L1/229 , A23L1/236 , A23L1/22
CPC classification number: A61K8/44 , A23L2/44 , A23L2/56 , A23L2/60 , A23L3/3526 , A23L3/3544 , A23L27/20 , A23L27/30 , A23L27/84 , A23L27/86 , A23V2002/00 , A61K2800/524 , A61Q11/00 , A23V2200/16 , A23V2250/264 , A23V2200/10 , A23V2250/06 , A23V2250/24
Abstract: Use of cationic surfactants, derived from the condensation of fatty acids and esterified dibasic amino acids, of the formula (I): occasionally leads to a bitter taste, when the compound is present in a large concentration. The bitter taste can be masked by combination with a second component selected from the list consisting of sucralose, neohespiridin (NHDC), β-cyclodextrin, mono ammonium glycyrrhizinate (MAG), banana, mentholyptus, sodium dodecyl sulphate (SDS), anetol, menthol, thaumatin, adenosine monophosphate (AMP), aloten, arginine, sodium acetate, arilic acids (ferulic acid, caffeic acid), sclareolide, maltol, anane, phosphatidic acid, eucalyptol, lactisole, lysozyme, lactoglobulin, timol, borneol, acetol, phosphothreonine, phosphotyrosine, phosphoserine, Masking flavour 501521T, Masking flavour 501522, saccharine, aspartame, MK22 N&A FL for masking #25682, MM24 Prosweet N&A FL Enhancer, neodiosmin, xylitol, stevia and Natural and Functional Flavour (NAF ® ).
Abstract translation: 衍生自式（I）的脂肪酸和酯化的二元氨基酸的缩合的阳离子表面活性剂的使用：当化合物以大的浓度存在时，偶尔会导致苦味。 可以通过与选自三氯蔗糖，新西兰白藜芦素（NHDC），β-环糊精，甘草酸甘草酸（MAG），香蕉，薄荷醇，十二烷基硫酸钠（SDS），茴香醚，薄荷醇的列表组合的第二组分的组合掩蔽苦味 ，马齿苋，阿魏酸，磷脂酸，桉油醇，乳清蛋白，溶菌酶，乳球蛋白，酪醇，冰片，丙酮醇，磷酸苏氨酸（阿司匹林），磷酸肌酸 ，磷酸酪氨酸，磷酸丝氨酸，掩蔽风味501521T，掩蔽风味501522，糖精，阿斯巴甜，MK22 N＆A FL用于掩蔽＃25682，MM24 Prosweet N＆A FL Enhancer，neodiosmin，木糖醇，甜菊和天然和功能性风味（NAF ）。
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公开(公告)号：WO2009101115A1
公开(公告)日：2009-08-20
申请号：PCT/EP2009/051587
申请日：2009-02-11
Applicant: LABORATORIOS MIRET, S.A. , ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , SEGRET PONS, Roger , PIERA EROLES, Eva
Inventor： ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , SEGRET PONS, Roger , PIERA EROLES, Eva
CPC classification number: A61Q11/00 , A23G3/364 , A23G3/40 , A23G4/066 , A23G4/12 , A23V2002/00 , A61K8/0216 , A61K8/44 , A61K8/494 , A23V2200/312 , A23V2200/222
Abstract: This invention relates to a use of a composition for protecting oral cavity and teeth containing ethyl-Nα-lauroyl-L-arginate HCI (LAE), a corresponding composition and a corresponding method for protecting teeth. Because of nearly epidemic incidence of dental erosion, there is a continuing need for improved products that provide protection against dental erosion. Hence, it is an object of the present invention to protect teeth against dental erosion. Surprisingly, it has been found that ethyl-Nα-lauroyl-L-arginate HCI (LAE) and its salts attach to teeth and provide protection of teeth from erosion especially caused by the action of acid in food products and drinks such as chewing gum and lozenges compositions. Special advantages of this invention are: (a) sustained coating of the teeth by LAE and its homologues; (b) the coating agent provides a source of neutralizing plaque acids by providing sustained base formation. This is because arginines in LAE is degraded by bacteria on tooth in the mouth to produce ammonia. Thus, this chemistry not only provides the coating protection but also generates base to maintain pH balance on a sustained basis; and (c) avoid the use of brushing with abrasive cleansers.
Abstract translation: 本发明涉及用于保护含有月桂酰-L-精氨酸乙酯钠盐（LAE）的口腔和牙齿的组合物的用途，相应的组合物和相应的保护牙齿的方法。 由于牙齿侵蚀发生几乎流行，因此继续需要提供防止牙齿侵蚀的改良产品。 因此，本发明的目的是保护牙齿免受牙齿侵蚀。 令人惊讶的是，已经发现乙基 - 月桂酰-L-精氨酸盐酸盐（LAE）及其盐附着在牙齿上，并且保护牙齿免受侵蚀，特别是由于酸在食品和饮料中的作用引起的，例如口香糖和 锭剂组合物 本发明的特殊优点是：（a）通过LAE及其同系物持续涂覆牙齿; （b）涂层剂通过提供持续的碱形成提供中和斑块酸源。 这是因为LAE中的精氨酸被口腔中的牙齿上的细菌降解以产生氨。 因此，这种化学不仅提供了涂层保护，而且还产生了基础，以持续地维持pH平衡; 和（c）避免使用磨料清洁剂进行刷牙。
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公开(公告)号：WO2009080563A1
公开(公告)日：2009-07-02
申请号：PCT/EP2008/067425
申请日：2008-12-12
Applicant: LABORATORIOS MIRET, S.A. , ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , SEGRET PONS, Roger , PIERA EROLES, Eva
Inventor： ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , SEGRET PONS, Roger , PIERA EROLES, Eva
IPC: A23B4/20 , A23L3/3526 , A23L3/3544
CPC classification number: A23L3/3526 , A23B4/20 , A23L3/3544
Abstract: Cationic surfactants derived from the condensation of fatty acids and esterified dibasic amino acids, such as from lauric acid and arginine, in particular the ethyl ester of the lauramide of the arginine monohydrochloride (LAE), may be used for the treatment of fish which is infected with parasites. The cationic surfactants of this type are effective against the larvae of parasites such as Anisakis.
Abstract translation: 衍生自脂肪酸和酯化二元氨基酸如月桂酸和精氨酸，特别是精氨酸一盐酸盐（LAE）的月桂酰胺的乙酯的缩合产生的阳离子表面活性剂可用于治疗感染的鱼 与寄生虫。 这种阳离子表面活性剂对寄生虫如Anisakis的幼虫有效。
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公开(公告)号：WO2009033508A2
公开(公告)日：2009-03-19
申请号：PCT/EP2007/060598
申请日：2007-10-05
Applicant: LABORATORIOS MIRET, S.A. , ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , SEGRET PONS, Roger , PIERA EROLES, Eva
Inventor： ROCABAYERA BONVILA, Xavier , FIGUERAS ROCA, Sergi , SEGRET PONS, Roger , PIERA EROLES, Eva
CPC classification number: A23B4/22 , A01N43/90 , A23B4/20 , A23C19/11 , A23L3/3463 , A23L3/34635 , A01N2300/00
Abstract: A solid composition comprising a cationic surfactant, such as the ethyl ester of the lauramide of the arginine monohydrochloride (LAE) and a polyene fungicide such as natamycin is provided. The solid composition is the basis for providing solutions of natamycin of increased concentration. The solid composition may be used for providing a dispersion of natamycin in a suitable liquid, such as tap water or an organic solvent. The dispersion may be further diluted with water. This leads to a solution of natamycin in water. The combination of the cationic surfactant and the polyene fungicide displays a biological effect which is stronger than the effect of each of the two components alone.
Abstract translation: 提供了包含阳离子表面活性剂（例如精氨酸一盐酸盐（LAE）的月桂酰胺的乙酯和多烯杀真菌剂如游霉素）的固体组合物。 固体组合物是提供浓度增加的那他霉素溶液的基础。 该固体组合物可用于提供纳他霉素在合适液体例如自来水或有机溶剂中的分散体。 分散体可以进一步用水稀释。 这导致纳他霉素在水中的溶液。 阳离子表面活性剂和多烯杀真菌剂的组合显示比单独的两种组分中的每一种的效果更强的生物效应。
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