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    MOLECULAR ARRAYS
    1.
    发明申请
    MOLECULAR ARRAYS 审中-公开

    公开(公告)号：WO2010151714A3

    公开(公告)日：2010-12-29

    申请号：PCT/US2010/039882

    申请日：2010-06-24

    Applicant: LIFE TECHNOLOGIES CORPORATION ,  ZHOU, Zhaohui ,  FRY, George A. ,  WOO, Sam Lee

    Inventor： ZHOU, Zhaohui ,  FRY, George A. ,  WOO, Sam Lee

    IPC: C12Q1/68 ,  G01N33/50

    Abstract: The disclosure relates generally to compositions, systems, and methods for use in preparing single molecule arrays, for example, arrays of single nucleic acid molecules, as well as arrays formed using such compositions, systems and methods by using a spacer which restricts the spacing between adjacent components of the array. In an exemplary embodiment, the array is formed by contacting a surface with a spacer-anchor complex including one or more spacers linked to an anchor, wherein the spacer comprises a linear or branched polymeric molecule folded to form a three-dimensional shape of desired size dimensions. The size of the folded spacer may optionally be adjusted to modulate the spacing distance between adjacent array components.

    THREAD WITH OPEN PORE FOR PLASTIC SURGERY
    7.
    发明申请
    THREAD WITH OPEN PORE FOR PLASTIC SURGERY 审中-公开
    螺纹打开用于塑料手术

    公开(公告)号：WO2007111407A1

    公开(公告)日：2007-10-04

    申请号：PCT/KR2006/005123

    申请日：2006-11-30

    Applicant: HANS BIOMED CORP. ,  PARK, Woo Sam ,  KIM, Tae Jun ,  YU, Won Suk ,  YOON, Young Jun

    Inventor： PARK, Woo Sam ,  KIM, Tae Jun ,  YU, Won Suk ,  YOON, Young Jun

    IPC: A61B17/064

    CPC classification number: A61B17/06166 ,  A61B2017/00792 ,  A61B2017/06176 ,  A61B2017/0618

    Abstract: Disclosed herein is a thread for use in plastic surgery, which is made of a polymer having excellent elasticity and resilience and has open pores on the surface thereof. The disclosed surgical thread is made of polyorganosiloxane, such as dimethylsiloxane or a derivative or copolymer thereof, having excellent elasticity and resilience and suitable for grafting, thus can move integrally with skin tissue upon the contraction and relaxation of muscles, and has formed on the surface thereof open pores instead of sharp protrusions, such that it can be easily infiltrated with tissue cells after surgical operations. Also, the surgical thread shows no side effect after surgical operations, can be used semi-permanently, and can give satisfaction to patients, thus greatly improving surgical lifting or sling effects.

    Abstract translation: 本文公开了一种用于整形手术的螺纹，其由具有优异弹性和弹性的聚合物制成，并且在其表面上具有开孔。 所公开的手术线由聚对苯二甲酸二甲基硅氧烷或其衍生物或共聚物制成，具有优异的弹性和弹性并且适合于接枝，因此可以在肌肉的收缩和松弛的情况下与皮肤组织一体移动并形成在表面上 其开孔而不是尖锐的突起，使得其可以在外科手术后容易地渗入组织细胞。 另外，外科手术后外科手术无副作用，半永久性使用，可使患者满意，大大提高手术起吊或吊索效果。

    NOVEL METHOD FOR ISOLATING SINGLE STRANDED PRODUCT
    10.
    发明申请
    NOVEL METHOD FOR ISOLATING SINGLE STRANDED PRODUCT 审中-公开
    用于分离单条产品的新方法

    公开(公告)号：WO2005054515A3

    公开(公告)日：2005-09-09

    申请号：PCT/US2004039700

    申请日：2004-11-24

    Applicant: APPLERA CORP ,  DIMSOSKI PERO ,  WOO SAM LEE

    Inventor： DIMSOSKI PERO ,  WOO SAM LEE

    IPC: C12Q1/68

    CPC classification number: C12Q1/6806 ,  C12Q1/6853 ,  C12Q2531/113 ,  C12Q2525/197

    Abstract: The present teachings relate to methods of purifying, isolating, separating, and identifying target nucleic acids. In some embodiments of the present teachings, an affinity moiety can be incorporated into one of the flanking primers of a nucleic acid amplification reaction primer pair. The reaction mixture can be contacted with a binding moiety specific for the affinity moiety, thereby allowing immobilization of the double stranded amplification product, separation of reaction components lacking the affinity moiety, and isolation of the target nucleic acid strand. Further, one of the flanking primers of the nucleic acid amplification reaction can comprise a label and a mobility modifier, thereby facilitating identification of the target nucleic acids. In some embodiments, the amplification reaction is multiplexed and comprises polymorphic microsatellites useful in human identification and the manufacturing of molecular size standards. Some embodiments of the present teachings provide for improved methods of performing electrokinetic injection.

    Abstract translation: 本教导涉及纯化，分离，分离和鉴定靶核酸的方法。 在本教导的一些实施方案中，亲和部分可以并入核酸扩增反应引物对的侧翼引物之一。 反应混合物可以与亲和部分特异性的结合部分接触，从而允许固定双链扩增产物，分离缺少亲和部分的反应组分和分离靶核酸链。 此外，核酸扩增反应的侧翼引物之一可以包含标记和迁移率调节剂，从而有助于鉴定靶核酸。 在一些实施方案中，扩增反应被多重化并且包含可用于人类鉴定和分子大小标准物的制备的多态性微卫星。 本教导的一些实施方案提供了进行电动注射的改进方法。

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