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公开(公告)号：WO2022078416A1
公开(公告)日：2022-04-21
申请号：PCT/CN2021/123674
申请日：2021-10-14
Applicant: JACOBIO PHARMACEUTICALS CO., LTD.
Inventor： LI, Runze , MA, Cunbo , LIAN, Zhenchang , XIONG, Jing , WANG, Yanping , LONG, Wei
IPC: C07C227/14 , C07D209/10 , C07F9/06 , C07D317/40 , A61K31/66 , A61K31/404 , A61P35/00
Abstract: Glutamine analogs, a composition containing the glutamine analogs and the use thereof.
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公开(公告)号：WO2023020523A1
公开(公告)日：2023-02-23
申请号：PCT/CN2022/112931
申请日：2022-08-17
Applicant: JACOBIO PHARMACEUTICALS CO., LTD.
Inventor： YANG, Hongwei , MA, Cunbo , GAO, Panliang , HAN, Huifeng , WANG, Peng , LI, Runze , LIU, Xiaoyu , WANG, Yanping , LONG, Wei , ZHANG, Wei
IPC: C07D403/14 , C07D401/14 , C07D413/14 , C07D417/14 , A61K31/4375 , A61P35/00
Abstract: A compound of Formula (I), (II) or (III), stereoisomer thereof, pharmaceutically acceptable salt thereof, pharmaceutically acceptable salt of the stereoisomer are disclosed.
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公开(公告)号：WO2023020521A1
公开(公告)日：2023-02-23
申请号：PCT/CN2022/112927
申请日：2022-08-17
Applicant: JACOBIO PHARMACEUTICALS CO., LTD.
Inventor： YANG, Hongwei , MA, Cunbo , GAO, Panliang , HAN, Huifeng , WANG, Peng , LI, Runze , LIU, Xiaoyu , WANG, Yanping , LONG, Wei , ZHANG, Wei
IPC: C07D471/04 , A61K31/519 , A61K31/517 , A61P35/00
Abstract: The invention relates to a compound of Formula (I), stereoisomer thereof, pharmaceutically acceptable salt thereof, pharmaceutically acceptable salt of the stereoisomer thereof, prodrug thereof, deuterated molecule thereof or conjugated form thereof; composition containing the same and the use thereof.
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公开(公告)号：WO2022078462A1
公开(公告)日：2022-04-21
申请号：PCT/CN2021/123878
申请日：2021-10-14
Applicant: JACOBIO PHARMACEUTICALS CO., LTD.
Inventor： LI, Runze , MA, Cunbo , LIAN, Zhenchang , XIONG, Jing , WANG, Yanping , LONG, Wei
IPC: C07C227/14 , C07D209/10 , C07F9/06 , C07D317/40 , A61K31/66 , A61K31/404 , A61P35/00
Abstract: Glutamine analogs are provided, a composition containing the glutamine analogs and the use thereof.
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Patent Agency Ranking
公开(公告)号：WO2023046135A1
公开(公告)日：2023-03-30
申请号：PCT/CN2022/121202
申请日：2022-09-26
Applicant: JACOBIO PHARMACEUTICALS CO., LTD.
Inventor： YANG, Hongwei , MA, Cunbo , GAO, Panliang , HAN, Huifeng , WANG, Peng , LI, Runze , ZHANG, Wei , LIU, Xiaoyu , WANG, Yanping , LONG, Wei
IPC: C07D498/14 , C07D498/22 , C07D498/16 , A61K31/55 , A61P35/00
Abstract: Provided are K-Ras mutant protein inhibitors of formula (I), a composition containing the same and the use thereof.
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公开(公告)号：WO2023020519A1
公开(公告)日：2023-02-23
申请号：PCT/CN2022/112919
申请日：2022-08-17
Applicant: JACOBIO PHARMACEUTICALS CO., LTD.
Inventor： YANG, Hongwei , MA, Cunbo , GAO, Panliang , HAN, Huifeng , WANG, Peng , LI, Runze , LIU, Xiaoyu , WANG, Yanping , LONG, Wei , ZHANG, Wei
IPC: C07D401/14 , C07D403/04 , C07D471/04 , A61K31/519 , A61P35/00 , C07D413/04 , C07D417/14 , C07D487/04 , C07D519/00
Abstract: A Compound of formula (I) or (II), a stereoisomer thereof, an atropisomer, a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable salt of the stereoisomer, a pharmaceutically acceptable salt of the atropisomer, a prodrug thereof, a deuterated molecule thereof or a conjugated form thereof is disclosed:
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公开(公告)号：WO2023020518A1
公开(公告)日：2023-02-23
申请号：PCT/CN2022/112918
申请日：2022-08-17
Applicant: JACOBIO PHARMACEUTICALS CO., LTD.
Inventor： YANG, Hongwei , MA, Cunbo , GAO, Panliang , HAN, Huifeng , WANG, Peng , LI, Runze , LIU, Xiaoyu , WANG, Yanping , LONG, Wei , ZHANG, Wei
IPC: C07D471/04 , A61K31/519 , A61P35/00
Abstract: Provided herein is a compound of Formula (IB), a stereoisomer thereof, a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable salt of the stereoisomer thereof, a prodrug thereof, a deuterated molecule thereof or a conjugated form thereof; composition containing the same and the use thereof.
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公开(公告)号：WO2022022612A1
公开(公告)日：2022-02-03
申请号：PCT/CN2021/109134
申请日：2021-07-29
Applicant: JACOBIO PHARMACEUTICALS CO., LTD.
Inventor： LI, Runze , MA, Cunbo , LIAN, Zhenchang , XIONG, Jing , ZHANG, Lei
IPC: C07D295/182 , C07D211/76 , C07D207/27 , C07D265/32 , C07D211/46 , C07D211/58 , C07D205/04 , C07D221/20 , C07D211/16 , C07D491/107 , C07D211/62 , C07D211/70 , C07D215/08 , C07D215/233 , C07D211/38 , C07D241/08 , C07D211/56 , C07D217/24 , C07D209/46 , C07D223/10 , C07D209/34 , C07D211/88 , C07D213/64 , C07D211/72 , C07D211/74 , C07D209/54 , C07D401/04 , C07D471/04 , C07D487/04 , C07D239/10 , C07D209/48 , C07D265/10 , C07D265/06 , C07D267/06 , C07D279/12 , C07K5/06 , A61K31/4965 , A61K31/535 , A61K31/445 , A61K31/40 , A61P35/00
Abstract: The invention relates to novel glutamine analogs shown as the formula I, a composition containing the glutamine analogs and the use thereof.
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9.发明申请NOVEL FUSED PYRIDINE DERIVATIVES USEFUL AS FAK/AURORA KINASE INHIBITORS 审中-公开新型融合吡啶衍生物可用作FAK / AURORA激酶抑制剂
公开(公告)号：WO2018019252A1
公开(公告)日：2018-02-01
申请号：PCT/CN2017/094474
申请日：2017-07-26
Applicant: JACOBIO PHARMACEUTICALS CO., LTD.
Inventor： ZHOU, Wenlai , LI, Runze , GAO, Panliang , WU, Xinping , BAI, Jinlong , YANG, Guiqun , WANG, Yanping , KANG, Di
IPC: C07D401/12 , C07D413/12 , C07D405/12 , C07D401/14 , C07D239/48 , C07D403/12 , A61K31/506 , A61P37/00 , A61P29/00
CPC classification number: A61P37/00 , A61P29/00 , C07D239/48 , C07D239/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/04
Abstract: This invention relates to certain novel pyrimidine derivatives of the Formula (I). The invention also relates to process for the preparation of the compound of the formula (I), pharmaceutical agents or compositions containing the compound or a method of using the compound for the treatment of proliferative diseases, such as cancer.
Abstract translation: 本发明涉及某些新的式（I）的嘧啶衍生物。 本发明还涉及制备式（I）化合物的方法，含有该化合物的药物或组合物或使用该化合物治疗增殖性疾病如癌症的方法。
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