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21.发明公开USE OF ENZYMES TO REDUCE ALDEHYDES FROM ALDEHYDE-CONTAINING PRODUCTS 审中-公开VERWENDUNG VON ENZYMEN ZUR REDUKTION VON ALDEHYDEN AUS ALDEHYDHALTIGEN PRODUKTEN
公开(公告)号：EP2417253A1
公开(公告)日：2012-02-15
申请号：EP10711898.6
申请日：2010-03-31
申请人： BASF SE
发明人： PIATESI, Andrea , HABICHER, Tilo , BÜSCHEL, Michael , WANG, Li-Wen , REICHERT, Jürgen , PACKE-WIRTH, Rainer , BALDENIUs, Kai-Uwe , KROMM, Erich , HAEFNER, Stefan , SCHWALB, Carsten , HÖFFKEN, Hans Wolfgang
CPC分类号： C12N9/0008 , C11D3/38654 , C12N15/63 , C12P7/00 , D06M15/423 , D06M16/003 , D06P1/0004 , D06P1/56
摘要： The invention relates to the use of an enzyme preparation which catalyzes the degradation of formaldehyde for reducing the formaldehyde content in a formaldehyde-containing formulation. In a preferred embodiment, the enzyme preparation contains a formaldehyde dismutase from a Pseudomonas putida strain. Further, the invention refers to a process for reducing the formal dehyde content in cross-linking agents for textile finishing or in polymer dispersions used, e.g. in construction chemistry. Further the invention relates to the use of an enzyme preparation which catalyzes the degradation of aldehydes for reducing the formaldehyde content in an aldehyde-containing formulation. Furthermore, the invention relates to a novel variant of the formaldehyde dismutase from Pseudomonas putida.
摘要翻译： 本发明涉及催化甲醛降解以降低含甲醛制剂中的甲醛含量的酶制剂的用途。 在优选的实施方案中，酶制剂含有恶臭假单胞菌菌株的甲醛歧化酶。 此外，本发明涉及用于降低用于织物整理的交联剂或所用聚合物分散体中的甲醛含量的方法。 在建筑化学。
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22.发明公开
公开(公告)号：EP2396401A1
公开(公告)日：2011-12-21
申请号：EP10708150.7
申请日：2010-02-12
申请人： BASF SE
发明人： SCHRÖDER, Hartwig , HAEFNER, Stefan , ABENDROTH, Gregory von , HOLLMANN, Rajan , RADDATZ, Aline , ERNST, Hansgeorg , GURSKI, Hans
CPC分类号： C12P7/46 , C12N1/32 , C12N9/1029 , C12R1/01 , C12Y203/01054
摘要： The present invention relates to bacterial strains, capable of utilizing glycerol as a carbon source for the fermentative production of succinic acid, wherein said strains are genetically modified so that they comprise a deregulation of their endogenous pyruvate-formate-lyase enzyme activity, as well as to methods of producing organic acids, in particular succinic acid, by making use of such microorganism. The present invention also relates to the downstream processing of the produced organic acids by cation exchange chromatography.
摘要翻译： 本发明涉及能够利用甘油作为发酵生产琥珀酸的碳源的细菌菌株，其中所述菌株被遗传修饰，使得它们包含其内源性丙酮酸 - 甲酸裂解酶活性的失调，以及 涉及通过利用这种微生物生产有机酸，特别是琥珀酸的方法。 本发明还涉及通过阳离子交换层析对所生产的有机酸的下游加工。
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公开(公告)号：EP3625337A1
公开(公告)日：2020-03-25
申请号：EP18727743.9
申请日：2018-05-18
申请人： BASF SE
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公开(公告)号：EP3384003A1
公开(公告)日：2018-10-10
申请号：EP16808598.3
申请日：2016-12-02
申请人： BASF SE
CPC分类号： C07K14/37 , C12N1/14 , C12N9/2437 , C12N15/01 , C12N15/80 , C12P19/14 , C12P21/00 , C12P21/02 , C12Q1/34
摘要： The present invention relates to a method of producing a recombinant polypeptide in a filamentous fungus which is genetically modified to decrease or eliminate the activity of cellulase regulator 1 (CLR1) and to express the recombinant polypeptide. The method further relates to a filamentous fungus Myceliophthora thermophila, which is genetically modified to decrease or eliminate the activity of CLR1 and to the use of this filamentous fungus in the production of a recombinant polypeptide.
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公开(公告)号：EP2491120B1
公开(公告)日：2015-12-23
申请号：EP10773880.9
申请日：2010-10-18
申请人： BASF SE
发明人： HAEFNER, Stefan , SERWE, Annegret , STOSIK, Beata
IPC分类号： C12N9/16
CPC分类号： C12N9/16 , A23K20/189
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公开(公告)号：EP1945043A2
公开(公告)日：2008-07-23
申请号：EP06819118.8
申请日：2006-10-23
申请人： BASF SE
发明人： ZELDER, Oskar , HEROLD, Andrea , KLOPPROGGE, Corinna , SCHRÖDER, Hartwig , HAEFNER, Stefan , HEINZLE, Elmar , WITTMANN, Christoph , KROEMER, Jens , PERO, Janice G. , YOCUM, R. Rogers , PATTERSON, Thomas A. , WILLIAMS, Mark , HERMAN, Theron
CPC分类号： C12P13/12 , A23K10/16 , A23K20/142 , A23K40/10 , C12N15/52
摘要： The present invention relates to microorganisms and processes for the efficient preparation of L-amino acids such as L-methionine. In particular, the present invention relates to microorganisms and processes in which the formation and/or accumulation of homolanthionine in the methionine pathway is reduced and/or prevented.
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公开(公告)号：EP1907558A2
公开(公告)日：2008-04-09
申请号：EP06800107.2
申请日：2006-07-18
申请人： BASF SE
发明人： ZELDER, Oskar , HAEFNER, Stefan , HEROLD, Andrea , KLOPPROGGE, Corinna , SCHRODER, Hartwig , YOCUM, R., Rogers , WILLIAMS, Mark, K.
IPC分类号： C12P13/12
CPC分类号： C12P13/12
摘要： The present invention features improved processes and organisms for the production of methionine. The invention demonstrates that a ΔmetF organism or a ΔmetE AmetH organism, for example, mutants of C. glutamicum or E. coli, can use a methyl capped sulfide source, e.g., dimethyl disulfide (DMDS), as a source of both sulfur and a methyl group, bypassing the need for MetH/MetΕ and MetF activity and the need to reduce sulfate, for the synthesis of methionine. Also described in this patent are data implicating MetY (also called MetZ) as an enzyme that incorporates a methyl capped sulfide source, e.g., DMDS, into methionine. A ΔmetF ΔmetB strain of C. glutamicum can use a methyl capped sulfide source, e.g., DMDS, as a source of both sulfide and a methyl group. Furthermore, methionine production by engineered prototrophic organisms that overproduce O-acetyl-homoserine was improved by the addition of a methyl capped sulfide source, e.g., DMDS.
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公开(公告)号：EP3419427A1
公开(公告)日：2019-01-02
申请号：EP17753727.1
申请日：2017-02-15
申请人： BASF SE
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29.发明授权
公开(公告)号：EP2870239B1
公开(公告)日：2018-10-31
申请号：EP13734062.6
申请日：2013-07-03
申请人： Wintershall Holding GmbH , BASF SE
发明人： BROCKMANN, Beata , HEROLD, Andrea , ZELDER, Oskar , HAEFNER, Stefan , FLECK, Christian , SCHRÖDER, Hartwig , GRANSTRÖM, Mari , SCHMIDT, Julia, Kristiane
CPC分类号： C12P19/04 , C12N9/1051 , C12Y204/01034
摘要： The present invention relates to genetically modified microorganisms capable of producing beta-glucans, characterized in that said genetically modified microorganism overexpresses (i) a polynucleotide encoding a polypeptide having 1,3-&bgr;-D-glucan synthase-activity, and/or (ii) a polypeptide having 1,3-&bgr;-D-glucan synthase-activity, compared to a corresponding non-modified control microorganism of the same strain. The present invention also relates to the use of a polynucleotide encoding a polypeptide having 1,3-&bgr;-D-glucan synthase-activity or the use of such a polypeptide for producing &bgr;-glucans. Furthermore, the present invention relates to methods for producing &bgr;-glucans comprising the introduction of a promoter upstream of a polynucleotide encoding a polypeptide having 1,3-&bgr;-D-glucan synthase-activity thereby increasing the expression of said polynucleotide, or a polynucleotide encoding a polypeptide having 1,3-&bgr;-D-glucan synthase-activity into a microorganism being able to synthesize &bgr;-glucans.
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公开(公告)号：EP3102674B1
公开(公告)日：2018-10-03
申请号：EP15738594.9
申请日：2015-02-06
申请人： BASF SE
发明人： KRAWCZYK, Joanna Martyna , HAEFNER, Stefan , SCHRÖDER, Hartwig , DANTAS COSTA, Esther , ZELDER, Oskar , VON ABENDROTH, Gregory , WITTMANN, Christoph , STELLMACHER, René , BECKER, Judith
CPC分类号： C12N15/52 , C12N1/02 , C12N9/0006 , C12N9/1029 , C12N9/1288 , C12N15/74 , C12P7/46 , C12Y101/01 , C12Y203/01054 , C12Y207/08031
摘要： The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the wcaJ-gene. The present invention also relates to a method for producing an organic compound and to the use of a modified microorganism.
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