摘要:
The present invention refers to a method for producing viruses, selected from the group of flaviviridae, poxviridae and reoviridae and vaccines derived therefrom as well as to cells cultured under protein-free conditions. These cells show improved capabilities for propagating viruses, and eliminate the need for costly and time-consuming viral passaging und purification.
摘要:
Plasmids are provided which upon introduction into a suitable host render the host capable of effecting expression of DNA encoding a desired polypeptide under the control of an osmB promoter. Such plasmids may be used to produce polypeptides such as superoxide dismutases, acetylcholinesterase, growth hormones and hepatitis antigen.
摘要:
A monoclonal antiboy that has a highly specific avidity with human-origin CETP (CETP inhibitory activity) and that is useful as a reagent for quantifying and purifying human-origin CETP and as a preventive or remedy for hyperlipemia and arteriosclerosis; and methods of quantifying and purifying human-origin CETP. The antibody permits the human-origin CETP contained in a sample to be quantified readily with a high sensitivity without the necessity for treating the sample with heat or surfactants. As the antibody has such a high CETP inhibitory activity, it is useful as medicines for treating or preventing various diseases such as hyperlipemia, hyper-high-density-lipoproteinemia, hypercholesterolemia, and arteriosclerosis.
摘要:
A liquid medium for nerve cells prepared by adding albumin to the culture supernatant of primary astroglia cells obtained by incubating the astroglia cells in a nutritional medium containing insulin and transferrin. By using the liquid medium, central nerve cells can be stably incubated. Thus, in low density incubation, synapses excellent in the elongation of axons can be quickly formed, while, in high density incubation, it is possible to provide cells forming a nervous network and being excellent in the stability over a prolonged storage.
摘要:
Aminosterol compounds are described that are useful as inhibitors of the sodium/proton exchanger (NHE). Methods of using such aminosterols compounds are also enclosed, including those employing compounds that are inhibitors of a spectrum of NHEs as well as those using compounds that are inhibitors of only one specific NHE. Advantageous screening techniques and assays for evaluating a compound's therapeutic activity are also disclosed.
摘要:
Schraubdübel für das Einbetonieren in eine Eisenbahnschwelle und die kraftschlüssige Verbindung mit einer Schwellenschraube, umfassend: einen Gewindeabschnitt (14) mit außen am Schraubdübel (10) angeordneten Außengewindegängen (18) sowie innen im Schraubdübel angeordneten Innengewindegängen (19); und einen im Einbauzustand nahe der Dübelöffnung (26) gelegenen oberen Teilabschnitt (16) ohne Außengewinde; dadurch gekennzeichnet, dass im oberen Teilabschnitt (16) ein Werkstoff mit hoher Elastizität angeordnet ist, der im Einbauzustand eine sich über die oberseitige Abschlussfläche (36) des oberen Teilabschnitts (16) hinaus nach oben erstreckende, herauskragende Erhebung bildet sowie den freien Öffnungsquerschnitt des Innenraums des oberen Teilabschnitts (16) verringert.