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公开(公告)号:JP3905573B2
公开(公告)日:2007-04-18
申请号:JP5263396
申请日:1996-02-16
发明人: ウーヴエ・ゲルラハ , デイーター・マニア , ハインツ・ゲーゲライン , ハインリヒ・エングラート , ヨーアヒム・カイザー
IPC分类号: A61K31/18 , C07C311/58 , A61K31/64 , A61P9/00 , A61P9/04 , A61P9/06 , A61P9/10 , C07C233/00 , C07C303/36 , C07C303/40 , C07C311/57 , C07C311/59 , C07C327/40 , C07C335/00 , C07C335/42
CPC分类号: C07C335/42 , C07C311/58 , C07C2601/02 , C07C2601/14 , Y10S514/821
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公开(公告)号:JP2836215B2
公开(公告)日:1998-12-14
申请号:JP20124390
申请日:1990-07-31
申请人: NIPPON SOODA KK
发明人: ISHIMITSU KEIICHI , SUZUKI JUNJI , OOISHI HARUHITO , YAMADA TOMIO , HATANO RENPEI , TAKAKUSA NOBUO
IPC分类号: C07D237/08 , A01N37/52 , A01N43/40 , A01N43/54 , A01N43/58 , A01N43/60 , A01N43/78 , A01N43/84 , A01N47/02 , C07C249/02 , C07C249/12 , C07C251/08 , C07C251/12 , C07C251/18 , C07C251/24 , C07C251/38 , C07C251/42 , C07C251/48 , C07C257/00 , C07C257/14 , C07C259/00 , C07C259/14 , C07C327/40 , C07D213/53 , C07D213/60 , C07D239/26 , C07D241/12 , C07D241/16 , C07D277/20 , C07D277/28 , C07D277/32 , C07D409/12 , C07D413/12
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公开(公告)号:JPH10287596A
公开(公告)日:1998-10-27
申请号:JP14249897
申请日:1997-05-30
申请人: SAGAMI CHEM RES
IPC分类号: A61K31/40 , A61K31/02 , A61K31/075 , A61K31/215 , A61K31/23 , A61K31/26 , A61K31/403 , A61K31/4035 , A61P35/00 , C07C17/093 , C07C19/10 , C07C19/14 , C07C41/16 , C07C43/12 , C07C67/11 , C07C69/62 , C07C247/04 , C07C253/30 , C07C255/19 , C07C327/40 , C07C331/04 , C07D209/48
摘要: PROBLEM TO BE SOLVED: To simply obtain a fluorine-containing compound by reacting an α- perfluoroalkylated alcohol with a Broensted acid in an aprotic solvent. SOLUTION: A perfluoroalkylsulfonic acid ester or perfluoroarylsulfonic acid ester of an α-perfluoroalkylated alcohol of the formula R R Rf C-OSO2 Rf [R and R are each H, an alkyl, an aromatic, an aralkyl, an alkenyl or an alkynyl or R and R together may form a ring; Rf and Rf are each a perfluoroalkyl or a perfluoro aromatic] is reacted with a Broensted acid of the formula M m Q n [M is a metal ion or polyatomic cation; Q is a conjugated base of the Broensted acid QHy ; (x), (y), (m) and (n) are each an integer satisfying the formula xm=yn] in a solvent such as DMF at -100 to 200 deg.C to provide the objective fluorine-containing compound of the formula (R R Rf C-)y Q (Q is a Broensted acid residue). The compound can be utilized as a synthetic intermediate for medicines and agrochemicals such as aticancer agents and enzyme inhibitors and functional materials such as ferroelectric liquid crystals.
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公开(公告)号:JPH09249610A
公开(公告)日:1997-09-22
申请号:JP8404596
申请日:1996-04-05
申请人: SUMITOMO CHEMICAL CO
发明人: MATSUO SANSHIRO , HIROSE TARO , IZUMI KEIICHI , SUZUKI MASAYA , SAKAMOTO NORIYASU , TSUSHIMA KAZUHIRO , SAITO SHIGERU , TAKANO JINKO
IPC分类号: C07D295/18 , A01N31/00 , C07C49/255 , C07C49/577 , C07C49/84 , C07C233/18 , C07C233/20 , C07C235/04 , C07C237/04 , C07C271/10 , C07C271/30 , C07C271/40 , C07C275/04 , C07C275/26 , C07C275/28 , C07C311/02 , C07C311/04 , C07C311/05 , C07C311/23 , C07C311/31 , C07C323/20 , C07C323/31 , C07C323/39 , C07C323/50 , C07C323/64 , C07C325/02 , C07C327/40 , C07C333/04 , C07C335/08 , C07C335/10 , C07D207/16 , C07D207/34 , C07D209/34 , C07D213/79 , C07D237/04 , C07D241/14 , C07D277/20 , C07D277/44 , C07D307/68 , C07D309/28 , C07D319/20 , C07D333/38
摘要: PROBLEM TO BE SOLVED: To obtain a dihalopropene compound having insecticidal activity and useful as an excellent insecticide. SOLUTION: This dihalopropene compound is represented by formula I [R1 is a 1-10C alkyl, etc.; R2 , R3 and R4 are each independently a halogen, a 1-3C haloalkyl, etc.; R5 , R6 and R7 are each independently H, trifluoromethyl, etc.; L is C=W, etc.; X is each independently Cl, Br, etc.; Y is O, NH, etc.; Z is O, S, etc.; (m) is an integer of 0-4; (n) is an integer of 0-2], e.g. 3,5-dichloro-4-(3- aminopropyloxy)-1-(3,3-dichloro-2-propenyloxy)benzene. The compound represented by formula I is obtained by reacting a compound represented by formula II with a compound represented by the formula L2 -CHX2 CH=CX2 (L2 is a halogen, mesyloxy or toluoxy) in the presence of a base (e.g. lithium hydroxide) in an inert solvent (e.g. acetone).
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公开(公告)号:JPH08183760A
公开(公告)日:1996-07-16
申请号:JP32732794
申请日:1994-12-28
申请人: DAIICHI SEIYAKU CO
发明人: AKASHI MITSURU
IPC分类号: C07C235/06 , C07C323/60 , C07C327/20 , C07C327/40 , C08F8/00 , C08F12/00 , C08F212/14 , C08F290/00 , C08F299/00
摘要: PURPOSE: To obtain a macromonomer, having N-isopropylacrylamide in a recurring unit, convertible into a graft copolymer having amphiphilicity and heat- sensitive phase transition properties, etc., and expectable of application to an interfacial modifier, a water-dispersible coating, a drug delivery system, etc. CONSTITUTION: This macromonomer of formula I [Q1 is H or CH3 ; Q2 is a group of formula II or III (R is a 1-10C alkylene); Q3 is 0 or NH; Q4 is R; Q5 is O or S; Y is O or two H atoms; n is 1-50]. The macromonomer of formula I is obtained by radically polymerizing N-isopropylacrylamide in the presence of a chain transfer agent having, e.g. amino, OH or carboxyl in the molecule (e.g. 2-mercaptoethylamine, 2-mercaptoethanol or β-mercaptopropionic acid) and reacting the resultant poly(N-isopropylacrylamide) having terminal amino, OH or carboxyl with a halomethylstyrene or an alkyl methacrylate dioxide.
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公开(公告)号:JPH07503946A
公开(公告)日:1995-04-27
申请号:JP50994093
申请日:1992-11-27
IPC分类号: A61K31/135 , A61K31/00 , A61K31/165 , A61K31/18 , A61K31/19 , A61K31/235 , A61K31/245 , A61K31/26 , A61K31/275 , A61P35/00 , A61P43/00 , C07C211/52 , C07C229/60 , C07C237/30 , C07C255/58 , C07C255/60 , C07C291/04 , C07C309/14 , C07C309/66 , C07C309/69 , C07C311/39 , C07C327/40 , C07C327/48 , C07D295/13 , C07D295/135
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公开(公告)号:JPH0770012A
公开(公告)日:1995-03-14
申请号:JP28916993
申请日:1993-11-18
申请人: LILLY CO ELI
IPC分类号: A61K31/395 , A61P29/00 , C07C217/46 , C07C225/14 , C07C229/30 , C07C233/49 , C07C237/16 , C07C237/22 , C07C255/30 , C07C275/20 , C07C275/46 , C07C317/28 , C07C317/44 , C07C327/40 , C07C327/44 , C07D217/26 , C07D221/02 , C07F7/10 , C07F7/18
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公开(公告)号:JPH05507931A
公开(公告)日:1993-11-11
申请号:JP51163191
申请日:1991-07-04
IPC分类号: A61K31/155 , A61K20060101 , A61K31/165 , A61K31/235 , A61K31/275 , A61P31/12 , A61P31/18 , C07C20060101 , C07C45/00 , C07C49/813 , C07C205/45 , C07C205/57 , C07C237/06 , C07C237/20 , C07C237/30 , C07C237/42 , C07C251/48 , C07C251/72 , C07C251/86 , C07C255/33 , C07C255/35 , C07C255/41 , C07C255/42 , C07C255/43 , C07C255/57 , C07C327/40 , C07C327/44 , C07D20060101 , C07D295/10 , C07D295/182 , C07D295/194
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公开(公告)号:JPH0510335B2
公开(公告)日:1993-02-09
申请号:JP9520884
申请日:1984-05-11
申请人: SUMITOMO CHEMICAL CO
发明人: TAKAHASHI JUNYA , KATO TOSHIRO , NOGUCHI HIROSHI , OGURI YUKIO , YAMAMOTO SHIGEO , KAMOSHITA KATSUZO
IPC分类号: A01N47/00 , A01N20060101 , A01N37/18 , A01N37/22 , A01N37/24 , A01N37/34 , A01N37/52 , A01N41/04 , A01N41/06 , A01N41/10 , A01N41/12 , A01N47/10 , A01N47/20 , A01N47/22 , A01N47/30 , A01N47/34 , A01N47/42 , A01N47/46 , C07C67/00 , C07C231/00 , C07C231/02 , C07C231/12 , C07C233/15 , C07C233/25 , C07C233/27 , C07C233/33 , C07C233/43 , C07C233/44 , C07C233/54 , C07C233/59 , C07C233/62 , C07C233/77 , C07C233/78 , C07C239/00 , C07C253/00 , C07C255/13 , C07C269/00 , C07C271/28 , C07C271/38 , C07C271/58 , C07C275/40 , C07C309/72 , C07C313/12 , C07C313/16 , C07C313/20 , C07C315/04 , C07C317/40 , C07C317/42 , C07C317/50 , C07C323/40 , C07C325/00 , C07C327/22 , C07C327/40 , C07C327/46 , C07C327/50 , C07C331/02 , C07C331/28 , C07C333/04 , C07C333/08 , C07C333/24 , C07C335/06 , C07C381/00 , C07D20060101
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公开(公告)号:JPS6242895B2
公开(公告)日:1987-09-10
申请号:JP8480179
申请日:1979-07-03
申请人: SHIONOGI & CO
发明人: HIRAI KENTARO , ISHIHA TERUYUKI , MATSUTANI SHIGERU , MAKINO ITSUO , FUJISHITA TOSHIO , TSUTSUMIUCHI MASAMI , OOTANI KOICHI
IPC分类号: C07D295/18 , A61K31/16 , A61K31/165 , A61K31/34 , A61K31/341 , A61K31/40 , A61K31/4015 , A61K31/41 , A61K31/415 , A61K31/42 , A61K31/4245 , A61K31/435 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/445 , A61K31/455 , A61K31/535 , A61K31/5375 , A61K31/5377 , A61P43/00 , C07C67/00 , C07C231/00 , C07C233/18 , C07C233/20 , C07C233/22 , C07C233/60 , C07C233/69 , C07C235/20 , C07C235/48 , C07C235/72 , C07C237/08 , C07C237/32 , C07C237/42 , C07C239/00 , C07C261/04 , C07C301/00 , C07C311/18 , C07C313/00 , C07C323/29 , C07C323/39 , C07C323/41 , C07C325/00 , C07C327/40 , C07C327/46 , C07C327/48 , C07C327/50 , C07D207/16 , C07D207/28 , C07D211/60 , C07D213/81 , C07D213/82 , C07D233/90 , C07D249/10 , C07D257/04 , C07D261/18 , C07D271/06 , C07D295/08 , C07D295/096 , C07D295/14 , C07D295/15 , C07D307/68 , C07D333/38 , C07D335/06 , C07D498/04
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