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公开(公告)号:US20250025545A1
公开(公告)日:2025-01-23
申请号:US18714854
申请日:2022-12-01
Applicant: Kanagawa Institute of Industrial Science and Technology , University of Tsukuba , Metagen, Inc.
Inventor: Shinji Fukuda , Gaku Nakato , Nozomu Obana , Risako Furukawa
IPC: A61K39/02 , C07K14/195
Abstract: Determination of the mechanism of allergy development in which a bacterium of the family Lachnospiraceae, which is an enteric bacterium, including Ruminococcus gnavus is involved and developing a method for preventing or treating allergies by intervening in the mechanism. Since the Ibp protein from a bacterium of the family Lachnospiraceae is involved in development of allergies, allergic reactions occurring in vivo can be prevented by administration or induction of in vivo production of a substance that binds to the Ibp protein.
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公开(公告)号:US20230210557A1
公开(公告)日:2023-07-06
申请号:US18117325
申请日:2023-03-03
Applicant: TOPPAN INC. , NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITY , KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
Inventor: Keiichi IMAI , Junji FUKUDA , Tatsuto KAGEYAMA , Ayaka NANMO
CPC classification number: A61B17/3468 , A61L27/38 , A61L27/52 , A61B2017/00752
Abstract: A cell transplanting kit includes a transplant including a cell group and a cell transplanting device. The cell transplanting device includes a needle-shaped portion that extends in a shape of a tube, and an aspiration portion configured to aspirate an interior of the needle-shaped portion. The needle-shaped portion is configured to attract the transplant by aspiration by the aspiration portion and take the transplant into the interior. The aspiration portion is configured to create an aspiration pressure in a range of −100 kPa to −0.1 kPa. The transplant includes a protection portion in a form of a gel covering at least a part of the cell group. The transplant has an outer diameter that is greater than or equal to a minimum value of the inner diameter of the needle-shaped portion. The protection portion has a jelly strength of greater than or equal to 100 g.
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公开(公告)号:US20230143373A1
公开(公告)日:2023-05-11
申请号:US17915913
申请日:2021-03-29
Inventor: Tomoyuki SHIMONO , Hiroshi ASAI , Kouhei OHNISHI , Takuya MATSUNAGA , Hironao KOBAYASHI , Masaya NAKAMURA , Mitsuru YAGI
IPC: A61B17/16
CPC classification number: A61B17/1626 , A61B17/1628 , A61B17/1671 , A61B2017/00123
Abstract: A medical apparatus includes a treatment mechanism, a slave actuator, an operation control unit, and a parameter acquisition unit. The treatment mechanism is used for treating a patient. The slave actuator causes the treatment mechanism to perform the treatment. The operation control unit calculates the control parameters related to the force tactile sensation, based on the information about the position that is detected along with the treatment and controls the operation of the slave actuator for causing the treatment mechanism to perform the treatment, based on the control parameters related to the force tactile sensation. The parameter acquisition unit acquires the control parameters related to the force tactile sensation.
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公开(公告)号:US20220326204A1
公开(公告)日:2022-10-13
申请号:US17764680
申请日:2020-10-02
Inventor: Tetsuya YAMADA , Toshihisa OSAKI , Hisatoshi MIMURA , Hirotaka SUGIURA , Shoji TAKEUCHI
Abstract: The present invention provides a measuring device which includes: a first container and a second container that are arranged adjacent to each other; and a partition wall provided between the first and second containers, the partition wall having a through hole(s) for forming a lipid bilayer(s). In this measuring device, a gas flow path(s) having a hydrophobic surface is/are formed in at least one of the first and second containers; the gas flow path(s) has/have an inlet and an outlet; the inlet and the outlet each communicate with the exterior of the measuring device; the gas flow path(s) open(s) into the container in which it/they is/are formed; and a gas flowing in the gas flow path(s) contacts the droplet filled in the container.
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公开(公告)号:US11447696B2
公开(公告)日:2022-09-20
申请号:US17273263
申请日:2020-07-22
Inventor: Junichi Tatami , Emi Takahashi , Takuma Takahashi
IPC: C09K11/77 , C09K11/02 , H01L33/50 , C04B35/645 , C04B35/053 , C04B41/45 , C04B41/50 , C09K11/08
Abstract: A fluorescent member according to present invention is composed of a sintered body for wavelength conversion containing a matrix containing magnesium oxide and magnesium hydroxide as main components, and phosphor particles dispersed in the matrix. A thermal conductivity of the fluorescent member is preferably 5 W/(m·K) or higher. A fluorescent member having both a satisfactory thermal conductivity and a satisfactory fluorescent property is provided without requiring a high-temperature sintering process (a high-temperature process at a temperature higher than 250° C.). Further, a method for manufacturing such a fluorescent member and a light-emitting apparatus using such a fluorescent member are provided.
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公开(公告)号:US10982140B2
公开(公告)日:2021-04-20
申请号:US16328136
申请日:2017-08-25
Applicant: Kanagawa Institute of Industrial Science and Technology , National University Corporation YOKOHAMA National University
Inventor: Takuma Takahashi , Junichi Tatami , Ippei Kokubun , Masahiro Yokouchi
IPC: C09K11/64 , C09K11/00 , C09K11/08 , C09K11/77 , C09K11/02 , C04B35/581 , C04B35/584 , C04B35/63
Abstract: A nitride phosphor particle dispersion-type sialon ceramic of the present invention includes a matrix formed of a sialon-based compound; and at least one nitride phosphor which is dispersed in the matrix and contains a luminescence center element.
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公开(公告)号:US20210107134A1
公开(公告)日:2021-04-15
申请号:US16978748
申请日:2019-03-07
Inventor: Tomoyuki SHIMONO , Takahiro MIZOGUCHI , Kouhei OHNISHI , Tetsuya TASHIRO
Abstract: A haptic transmission system includes a master device and a slave device. The master device controls position and force in an operation of the master device based on information acquired from the operation of the master device and information relating to a response of the slave device, and compensates for a communication delay in a communication path with respect to the control of force. The slave device controls speed and force in an operation of the slave device based on information acquired from the operation of the slave device and information relating to control from the master device.
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公开(公告)号:US20210079345A1
公开(公告)日:2021-03-18
申请号:US16968323
申请日:2019-02-04
Applicant: National University Corporation Yokohama National University , Kanagawa Institute of Industrial Science and Technology
Inventor: Junji Fukuda , Tatsuto Kageyama , Sugi Hirano
Abstract: Provided are a method and kit for growth of hair follicle epithelial stem cells on a large scale while maintaining their hair regeneration ability. The culture method for hair follicle epithelial stem cells includes: an accumulating step of forming an accumulation of hair follicle epithelial stem cells by inoculating a cell culture vessel with the hair follicle epithelial stem cells; a mixing step of producing a mixture of an extracellular matrix component and the accumulation of the hair follicle epithelial stem cells by adding the extracellular matrix component to the accumulation of the hair follicle epithelial stem cells; and a culturing step of culturing the hair follicle epithelial stem cells by adding a medium to the mixture. The culture kit for hair follicle epithelial stem cells includes: a cell culture vessel formed of a material having oxygen permeability; an extracellular matrix component; and a medium.
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公开(公告)号:US20210052822A1
公开(公告)日:2021-02-25
申请号:US16982417
申请日:2019-03-22
Applicant: National University Corporation Tokyo Medical and Dental University , Kanagawa institute of Industrial Science and Technology
Inventor: Akira MATSUMOTO , Slyuan CHEN
Abstract: A gel composition which can be used suitably for a microneedle that can release insulin according to the glucose concentration in a self-regulated manner and a microneedle using the same. An insulin delivery microneedle comprises a base part fabricated with silk fibroin, at least one needle part integrally provided on the base part, and an insulin reservoir. At least a tip portion of the needle part comprises a composite gel composition comprising a copolymer comprising a phenylboronic acid-based monomer unit and silk fibroin.
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公开(公告)号:US20190267655A1
公开(公告)日:2019-08-29
申请号:US16320354
申请日:2017-05-31
Applicant: TOKYO INSTITUTE OF TECHNOLOGY , TEIJIN LIMITED , KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
Inventor: Takeo YAMAGUCHI , Yuhei OSHIBA , Hidenori OHASHI , Jin TOMATSU , Koji FURUYA , Takao OHNO , Mami NANBU
IPC: H01M8/106 , H01M8/1062 , H01M8/1039 , H01M8/1086 , H01M8/1081 , H01M8/1025 , C25B13/08 , C25B1/10
Abstract: To provide an electrolyte membrane that exhibits high proton conductivity even at low humidity, the electrolyte membrane includes a composite membrane including: a microporous polyolefin membrane that has an average pore diameter of 1 to 1000 nm and a porosity of 50 to 90% and that can be impregnated with a solvent having a surface free energy of 28 mJ/m2 or more, and an electrolyte containing a perfluorosulfonic acid polymer having an EW of 250 to 850 loaded into the pores of the microporous polyolefin membrane, wherein the membrane thickness of the composite membrane is 1 to 20 μm.
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