-
公开(公告)号：US20170363631A1
公开(公告)日：2017-12-21
申请号：US15534203
申请日：2015-12-09
发明人： Joshua LaBaer , Jie Wang , Ji Qiu , Garrick Wallstrom , Karen Anderson , Jin Park , Jonine Figueroa
IPC分类号： G01N33/574 , C12Q1/68 , C07K16/30 , C12N15/11
CPC分类号： G01N33/57415 , C07K16/3015 , C12N15/11 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G01N33/564
摘要： Cancer patients make antibodies to tumor-derived proteins that are potential biomarkers for early detection. Twenty-eight antigens have been identified as potential biomarkers for the early detection of basal-like breast cancer (Tables 1, 2). Also, a 13-AAb classifier has been developed that differentiate patients with BLBC from healthy controls with 33% sensitivity at 98% specificity (Table 3).
-
公开(公告)号：US12085569B2
公开(公告)日：2024-09-10
申请号：US17940883
申请日：2022-09-08
申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人： Joshua LaBaer , Jie Wang , Ji Qiu , Garrick Wallstrom , Karen Anderson , Jin Park , Jonine Figueroa
IPC分类号： G01N33/574 , C07K16/30 , C12Q1/6886 , G01N33/564 , C12N15/11
CPC分类号： G01N33/57415 , C07K16/3015 , C12Q1/6886 , G01N33/564 , C12N15/11 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158
摘要： Cancer patients make antibodies to tumor-derived proteins that are potential biomarkers for early detection. Twenty-eight antigens have been identified as potential biomarkers for the early detection of basal-like breast cancer (Tables 1, 2). Also, a 13-AAb classifier has been developed that differentiate patients with BLBC from healthy controls with 33% sensitivity at 98% specificity (Table 3).
-
公开(公告)号：US20220163531A1
公开(公告)日：2022-05-26
申请号：US17563279
申请日：2021-12-28
申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
IPC分类号： G01N33/574
摘要： Compositions and methods relating to a panel of antigen biomarkers for the early detection of ovarian cancer. The compositions and methods encompass antigen biomarkers coupled to a substrate, with the biomarkers being selected from the group consisting of one or more of ICAM3, CTAG2, p53, STYXL1, PVR, POMC, NUDT11, TRIM39, UHMK1, KSR1, and NXF3.
-
公开(公告)号：US20200377871A1
公开(公告)日：2020-12-03
申请号：US16632782
申请日：2018-04-27
发明人： Radwa Ewaisha , Samira Kiani , Shayesteh Roshdi Ferdosi , Karen Anderson , Farzaneh Moghadam , Sri Krishna , Mo Reza Ebrahimkhani
IPC分类号： C12N9/22 , G01N33/573
摘要： Provided herein are methods and compositions for reducing an undesirable T cell immune response in human patients prior to and/or during gene therapy using CRISPR/Cas9-based genetic modulation.
-
公开(公告)号：US20230187026A1
公开(公告)日：2023-06-15
申请号：US17924079
申请日：2021-05-10
发明人： Karen Anderson , Abhishek Singharoy , Eric Wilson
摘要： A consensus MHC-I binding and processing prediction workflow, methods and systems are described, for improving T-cell immunity against threats such as viruses and cancer. The methods and systems can also be used to determine population fitness against a target antigen such as a pathogen or cancer.
-
公开(公告)号：US11525831B2
公开(公告)日：2022-12-13
申请号：US16743906
申请日：2020-01-15
申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人： Joshua LaBaer , Jie Wang , Ji Qui , Garrick Wallstrom , Karen Anderson , Jin Park , Jonine Figueroa
IPC分类号： G01N33/564 , G01N33/574 , C07K16/30 , C12Q1/6886 , C12N15/11
摘要： Cancer patients make antibodies to tumor-derived proteins that are potential biomarkers for early detection. Twenty-eight antigens have been identified as potential biomarkers for the early detection of basal-like breast cancer (Tables 1, 2). Also, a 13-AAb classifier has been developed that differentiate patients with BLBC from healthy controls with 33% sensitivity at 98% specificity (Table 3).
-
公开(公告)号：US11243208B2
公开(公告)日：2022-02-08
申请号：US16317184
申请日：2017-07-11
申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
IPC分类号： G01N31/00 , G01N33/53 , G01N33/574
摘要： Compositions and methods relating to a panel of antigen biomarkers for the early detection of ovarian cancer. The compositions and methods encompass antigen biomarkers coupled to a substrate, with the biomarkers being selected from the group consisting of one or more of ICAM3, CTAG2, p53, STYXL1, PVR, POMC, NUDT11, TRIM39, UHMK1, KSR1, and NXF3.
-
公开(公告)号：US11208640B2
公开(公告)日：2021-12-28
申请号：US16632782
申请日：2018-04-27
发明人： Radwa Ewaisha , Samira Kiani , Shayesteh Roshdi Ferdosi , Karen Anderson , Farzaneh Moghadam , Sri Krishna , Mo Reza Ebrahimkhani
IPC分类号： C12N9/22 , G01N33/573 , A61K48/00
摘要： Provided herein are methods and compositions for reducing an undesirable T cell immune response in human patients prior to and/or during gene therapy using CRISPR/Cas9-based genetic modulation.
-
公开(公告)号：US20190302122A1
公开(公告)日：2019-10-03
申请号：US16317184
申请日：2017-07-11
申请人： Benjamin KATCHMAN , Karen ANDERSON , Garrick WALLSTROM , Joshua LABAER , Daniel CRAMER , ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
IPC分类号： G01N33/574
摘要： Compositions and methods relating to a panel of antigen biomarkers for the early detection of ovarian cancer. The compositions and methods encompass antigen biomarkers coupled to a substrate, with the biomarkers being selected from the group consisting of one or more of ICAM3, CTAG2, p53, STYXL1, PVR, POMC, NUDT11, TRIM39, UHMK1, KSR1, and NXF3.
-
10.发明申请公开(公告)号：US20170059563A1
公开(公告)日：2017-03-02
申请号：US15308330
申请日：2015-05-01
IPC分类号： G01N33/543 , G01N21/64 , A61B5/00 , B01L3/00
CPC分类号： G01N33/54366 , A61B5/0071 , A61B5/6802 , B01L3/502707 , B01L3/502715 , B01L3/502761 , B01L2200/025 , B01L2200/12 , B01L2300/0636 , B01L2300/0654 , B01L2300/0819 , B01L2300/0825 , B01L2300/087 , B01L2300/123 , G01N21/05 , G01N21/6428 , G01N21/6454 , G01N33/54373 , G01N2021/6439 , G01N2201/0221
摘要： A fully integrated miniaturized optical biosensor and methods of making the same are disclosed. The biosensor may include a fluid transport system and an optical system.
摘要翻译： 公开了一种完全集成的小型化光学生物传感器及其制造方法。 生物传感器可以包括流体输送系统和光学系统。
-
-
-
-
-
-
-
-
-
搜索结果
23 条记录 (耗时 0.031 秒)
