公开(公告)号：US10202324B2

公开(公告)日：2019-02-12

申请号：US15571107

申请日：2016-05-04

Applicant: BASF SE

Inventor： Nicolas Vautravers ,  Joaquim Henrique Teles ,  Ralf Pelzer ,  Daniel Schneider ,  Florian Garlichs ,  Andreas Keller ,  Andrei-Nicolae Parvulescu ,  Ulrich Müller

IPC: C07C45/54 ,  C07C45/78 ,  C07C67/39 ,  C07C45/64

Abstract: A process for preparing 2,6-dimethyl-5-heptenal, comprising oxidizing citral of which more than 50% are present as geranial with hydrogen peroxide in the presence of a catalyst comprising a Baeyer-Villiger oxidation catalyst, preferably a tin-containing molecular sieve.

公开(公告)号：US09073826B2

公开(公告)日：2015-07-07

申请号：US13687156

申请日：2012-11-28

Applicant: BASF SE

Inventor： Klaus Ebel ,  Tobias Voitl ,  Andreas Keller ,  Stefan Rüdenauer ,  Karsten Bartling ,  Bjorn Langlotz ,  Jochen Steiner

IPC: C07C303/22 ,  C07C309/15 ,  C07C303/32 ,  C07C303/44

CPC classification number: C07C303/22 ,  C07C303/32 ,  C07C303/44 ,  C07C309/15

Abstract: A process for preparing salts of acrylamido-2-methylpropanesulfonic acid (A) using the steps of: preparing a solution of a contaminated salt of acrylamido-2-methyl-propanesulfonic acid (A) in an anhydrous organic solvent (L) using at least one basic component (B) selected from the group of alkali metal oxides, alkaline earth metal oxides, alkali metal hydroxides, alkaline earth metal hydroxides and amines of the formula (I) NRaRbRc  (I) where the Ra, Rb and Rc radicals are each independently: hydrogen, C1-C4-alkyl, hydroxy-C1-C4-alkyl or C1-C4-alkoxy, where the molar ratio of compound (A) to the basic component (B) is 1:1 to 1:3, recovering the dissolved salt of compound (A) by crystallization or by precipitation, by altering the temperature and/or the pressure and/or the concentration of the salt in the solution. This leads to salts which are low in by-products and are particularly suitable for polymerization.

Abstract translation: 一种使用以下步骤制备丙烯酰氨基-2-甲基丙磺酸（A）的盐的方法：使用至少在无水有机溶剂（L）中制备丙烯酰胺基-2-甲基 - 丙磺酸（A）的污染盐的溶液 选自碱金属氧化物，碱土金属氧化物，碱金属氢氧化物，碱土金属氢氧化物和式（I）NRaRbRc（I）的胺的一种碱性组分（B），其中R a，R b和R c基团各自为 独立地：氢，C1-C4-烷基，羟基-C1-C4-烷基或C1-C4-烷氧基，其中化合物（A）与碱性组分（B）的摩尔比为1:1至1:3，回收 化合物（A）的溶解盐通过结晶或沉淀，改变溶液中盐的温度和/或压力和/或浓度。 这导致副产物低的盐，特别适用于聚合。

公开(公告)号：US20130137893A1

公开(公告)日：2013-05-30

申请号：US13687156

申请日：2012-11-28

Applicant: BASF SE

Inventor： Klaus Ebel ,  Tobias Voitl ,  Andreas Keller ,  Stefan Rüdenauer ,  Karsten Bartling ,  Bjorn Langlotz ,  Jochen Steiner

IPC: C07C303/22 ,  C07C309/15

CPC classification number: C07C303/22 ,  C07C303/32 ,  C07C303/44 ,  C07C309/15

Abstract: A process for preparing salts of acrylamido-2-methylpropanesulfonic acid (A) using the steps of: preparing a solution of a contaminated salt of acrylamido-2-methyl-propanesulfonic acid (A) in an anhydrous organic solvent (L) using at least one basic component (B) selected from the group of alkali metal oxides, alkaline earth metal oxides, alkali metal hydroxides, alkaline earth metal hydroxides and amines of the formula (I) NRaRbRc  (I) where the Ra, Rb and Rc radicals are each independently: hydrogen, C1-C4-alkyl, hydroxy-C1-C4-alkyl or C1-C4-alkoxy, where the molar ratio of compound (A) to the basic component (B) is 1:1 to 1:3, recovering the dissolved salt of compound (A) by crystallization or by precipitation, by altering the temperature and/or the pressure and/or the concentration of the salt in the solution. This leads to salts which are low in by-products and are particularly suitable for polymerization.

Abstract translation: 一种使用以下步骤制备丙烯酰氨基-2-甲基丙磺酸（A）的盐的方法：使用至少在无水有机溶剂（L）中制备丙烯酰氨基-2-甲基 - 丙磺酸（A）的污染盐的溶液 选自碱金属氧化物，碱土金属氧化物，碱金属氢氧化物，碱土金属氢氧化物和式（I）NRaRbRc（I）的胺的一种碱性组分（B），其中R a，R b和R c基团各自为 独立地：氢，C1-C4-烷基，羟基-C1-C4-烷基或C1-C4-烷氧基，其中化合物（A）与碱性组分（B）的摩尔比为1:1至1:3，回收 化合物（A）的溶解盐通过结晶或沉淀，改变溶液中盐的温度和/或压力和/或浓度。 这导致副产物低的盐，特别适用于聚合。

公开(公告)号：US10919827B2

公开(公告)日：2021-02-16

申请号：US16636474

申请日：2018-08-10

Applicant: BASF SE

Inventor： Albert Werner ,  Miriam Bru Roig ,  Andrei-Nicolae Parvulescu ,  Roland Minges ,  Andreas Keller ,  Stephan Maurer ,  Ulrich Mueller ,  Wolfgang Siegel

IPC: C07C29/80 ,  C07C29/38 ,  C07C33/025 ,  C07C33/03 ,  B01D3/14 ,  B01J29/70 ,  B01J37/02 ,  B01J37/08

Abstract: The present invention relates to a process for recovering 3-methylbut-3-en-1-ol from a feed stream F1 comprising 3-methylbut-3-en-1-ol, one or more solvents, water, and isobutene, wherein 3-methylbut-3-en-1-ol, the one or more solvents and water are separated from isobutene by distillation, the process comprising subjecting the feed stream F1 to distillation conditions in a distillation unit, obtaining a bottoms stream B1 which is enriched in -methylbut-3-en-1-ol, in the one or more solvents and in water compared to the feed stream F1 subject The present invention relates to a process for recovering 3-methylbut-3-en-1-ol from a feed stream F1 comprising 3-methylbut-3-en-1-ol, one or more solvents, water, and isobutene, wherein 3-methylbut-3-en-1-ol, the one or more solvents and water are separated from isobutene by distillation, the process comprising subjecting the feed stream F1 to distillation conditions in a distillation unit, obtaining a bottoms stream B1 which is enriched in -methylbut-3-en-1-ol, in the one or more solvents and in water compared to the feed stream F1 subjected to distillation conditions, and a top stream T1 which is enriched in isobutene, further subjecting the bottoms stream B1 to distillation conditions in a second distillation unit and obtaining a bottoms stream B2 which is enriched in 3-methylbut-3-en-1-ol compared to the bottoms stream B1 and a top stream T2 which is enriched in water compared to the bottoms stream B1, further subjecting the bottoms stream B2 to distillation conditions in a third distillation unit and obtaining a top stream T3 which is enriched in 3-methylbut-3-en-1-ol compared to the bottoms stream B2 and a bottoms stream B3. ted to distillation conditions, and a top stream T1 which is enriched in isobutene, further subjecting the bottoms stream B1 to distillation conditions in a second distillation unit and obtaining a bottoms stream B2 which is enriched in 3-methylbut-3-en-1-ol compared to the bottoms stream B1 and a top stream T2 which is enriched in water compared to the bottoms stream B1, further subjecting the bottoms stream B2 to distillation conditions in a third distillation unit and obtaining a top stream T3 which is enriched in 3-methylbut-3-en-1-ol compared to the bottoms stream B2 and a bottoms stream B3.

公开(公告)号：US09975837B2

公开(公告)日：2018-05-22

申请号：US15536524

申请日：2015-12-18

Applicant: BASF SE

Inventor： Mathias Schelwies ,  Rocco Paciello ,  Gunnar Heydrich ,  Günter Wegner ,  Gerd-Dieter Tebben ,  Martin Haubner ,  Andreas Keller ,  Oliver Bey ,  Stephanie Renz ,  Georg Seeber

IPC: C07C45/62 ,  C07C29/56 ,  C07C29/17

CPC classification number: C07C45/62 ,  C07B2200/07 ,  C07C29/172 ,  C07C29/56 ,  C07C2601/14 ,  C07C47/21 ,  C07C47/02 ,  C07C35/12 ,  C07C35/17

Abstract: The present invention relates to a process for the preparation of an optically active carbonyl compound by asymmetric hydrogenation of a prochiral α,β-unsaturated carbonyl compound with hydrogen in the presence of at least one optically active transition metal catalyst that is soluble in the reaction mixture and which has rhodium as catalytically active transition metal and a chiral, bidentate bisphosphine ligand, wherein the reaction mixture during the hydrogenation of the prochiral α,β-unsaturated carbonyl compound additionally comprises at least one compound of the general formula (I): in which R1, R2: are identical or different and are C6- to C10-aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C1- to C6-alkyl, C3- to C6-cycloalkyl, C6- to C10-aryl, C1- to C6-alkoxy and amino; Z is a group CHR3R4 or aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C1- to C6-alkyl, C3- to C6-cycloalkyl, C6- to C10-aryl, C1- to C6-alkoxy and amino, wherein R3 and R4 are as defined in the claims and the description.

公开(公告)号：US09856199B2

公开(公告)日：2018-01-02

申请号：US15123325

申请日：2015-03-06

Applicant: BASF SE

Inventor： Volker Hickmann ,  Stefan Rüdenauer ,  Martine Dehn ,  Andreas Keller ,  Stephanie Renz ,  Daniel Schneider

IPC: C07C45/00 ,  B01J23/00 ,  C07C45/51 ,  A61K8/35 ,  A61Q11/00 ,  C07C45/29 ,  A61Q19/00 ,  B01J23/889 ,  C07C49/407

CPC classification number: C07C45/512 ,  A61K8/35 ,  A61K2800/10 ,  A61Q11/00 ,  A61Q19/00 ,  B01J23/8892 ,  C07C45/29 ,  C07C45/298 ,  C07C49/407 ,  C07C2601/14

Abstract: The present invention relates to a process for reacting isopulegol to menthone in the gas phase and to the use of the reaction products thus prepared as additives in foods, cosmetics, pharmaceutical products, tobacco formulations, household products, and laundry care products.

公开(公告)号：US20150246864A1

公开(公告)日：2015-09-03

申请号：US14709948

申请日：2015-05-12

Applicant: BASF SE

Inventor： Rudolf Schuch ,  Stefan Rüdenauer ,  Klaus Ebel ,  Ralf Pelzer ,  Andreas Keller

IPC: C07C29/44 ,  C07C29/80 ,  C07C29/19

CPC classification number: C07C29/44 ,  B01J21/08 ,  B01J23/462 ,  B01J23/56 ,  B01J33/00 ,  B01J35/0026 ,  B01J35/008 ,  B01J35/023 ,  B01J35/08 ,  B01J35/1019 ,  B01J35/1042 ,  B01J35/1061 ,  B01J35/108 ,  B01J37/0203 ,  B01J37/18 ,  C07C29/19 ,  C07C29/80 ,  C07C2601/14 ,  C11B9/0061 ,  C07C33/20 ,  C07C31/1355

Abstract: A process for preparing 4-cyclohexyl-2-methyl-2-butanol, comprising: a) reaction of styrene with isopropanol at elevated temperature to obtain 2-methyl-4-phenyl-2-butanol, and b) heterogeneously catalyzed hydrogenation of 2-methyl-4-phenyl-2-butanol over a catalyst suitable for ring hydrogenation of aromatics, where the molar ratio of the styrene used in step a) to the isopropanol used in step a) is in the range from 1:below 5 to 1:0.5.

Abstract translation: 一种制备4-环己基-2-甲基-2-丁醇的方法，包括：a）在升高的温度下使苯乙烯与异丙醇反应得到2-甲基-4-苯基-2-丁醇，和b）异构催化氢化2 - 甲基-4-苯基-2-丁醇，其适用于芳族化合物的环加氢，其中步骤a）中使用的苯乙烯的摩尔比与步骤a）中使用的异丙醇的摩尔比在1：低于5至 1：0.5。

公开(公告)号：US12172956B2

公开(公告)日：2024-12-24

申请号：US16969680

申请日：2019-02-13

Applicant: BASF SE

Inventor： Mathias Schelwies ,  Wolfgang Siegel ,  Rocco Paciello ,  Andreas Keller

IPC: C07C51/353 ,  C07C51/09 ,  C12P7/6427 ,  C12P7/6436

Abstract: The present invention relates to a method for isomerizing a 3-(Z)-unsaturated carboxylic acid of the formula 1-Z or a salt thereof, wherein R2 is C1-C24-alkyl, C2-C24-alkenyl having 1, 2, 3 or more than 3 C—C double bonds, unsubstituted or substituted C5-C12-cycloalkyl, or unsubstituted or substituted aryl; R1 is hydrogen or has one of the definitions specified for R2; with the proviso that R2 has a higher priority than R1 in accordance with IUPAC; to give a 3-(E)-unsaturated carboxylic acid of the formula I-E or a salt thereof, wherein the isomerization of the compound of the formula 1-Z is effected in the presence of an anhydride of an organic acid and a base or in the presence of a ketene of formula CR11R12C(0), wherein R11 and R12 are as defined in the claims and in the specification and a base. In particular, the present invention relates to a method for preparing compositions with increased content of (3E,7E)-homofarnesylic acid starting from compositions comprising (3Z,7E)- and (3E,7E)-homofarnesylic acid.

公开(公告)号：US11098075B2

公开(公告)日：2021-08-24

申请号：US15510268

申请日：2015-09-11

Applicant: BASF SE

Inventor： Michael Puhl ,  Klaus Ditrich ,  Andreas Keller ,  Pepa Dimitrova ,  Melanie Weingarten ,  Wolfgang Siegel

IPC: C07H15/26 ,  C07H3/06 ,  C07H1/00 ,  A23L33/10

Abstract: The present invention relates to a method for preparing 2′-O-fucosyllactose, the 2′-O-fucosyllactose obtainable by this method and the use thereof. The method comprises reacting the persilylated, protected fucose derivatives of the formula (I) below, with at least one tri(C1-C6-alkyl)silyl iodide and subsequently reacting the product thus obtained with the compound of the general formula (II), in the presence of a base. In the formulae (I) and (II), the variables are each defined as follows: RSi are the same or different and are a residue of the formula SiRaRbRc; R1 is a C(═O)—R11 residue or an SiR12R13R14 residue, R2 are the same or different and are C1-C8-alkyl or together form a linear C3-C6-alkanediyl, which is unsubstituted or has 1 to 6 methyl groups as substituents; R3 are the same or different and are C1-C8-alkyl or together form a linear C1-C4-alkanediyl, which is unsubstituted or has 1 to 6 methyl groups as substituents.

公开(公告)号：US10889547B2

公开(公告)日：2021-01-12

申请号：US16311206

申请日：2017-06-22

Applicant: BASF SE

Inventor： Sumana Roy ,  Andreas Keller ,  Wolfgang Siegel ,  Michael Joedecke ,  Martin Haubner

IPC: C07D215/20 ,  B01D3/14 ,  A23K20/132 ,  A23L3/3526 ,  B01D3/10 ,  B01J19/30

Abstract: The present invention relates to a process for purifying ethoxyquin by distillation, to high-purity ethoxyquin obtainable by means of distillative purification and to the use thereof, particularly as additive in foodstuffs and feedstuffs.