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公开(公告)号:US10052045B2
公开(公告)日:2018-08-21
申请号:US14441184
申请日:2012-12-21
Applicant: Colgate-Palmolive Company
Inventor: Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid
CPC classification number: A61B5/08 , A61B5/082 , A61B10/00 , A61B2010/0087 , A61K8/33 , A61K8/35 , A61K8/55 , A61Q11/00 , G01N33/497 , G01N2033/4975 , Y10T436/182
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.
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公开(公告)号:US20150293075A1
公开(公告)日:2015-10-15
申请号:US14441962
申请日:2012-12-21
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid , Ariel Haskel
IPC: G01N33/497 , A61K8/33 , A61K8/35 , A61Q11/00 , A61K8/24
CPC classification number: G01N33/497 , A61K8/24 , A61K8/33 , A61K8/35 , A61K8/4913 , A61K8/4973 , A61K2800/591 , A61Q11/00
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from coffee. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a sample of exhaled breath from the cleaned oral cavity to provide a test result representing a amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a sample of exhaled breath from the oral cavity to provide a test result representing an amount of the at least one oral malodor component detected in the exhaled breath.
Abstract translation: 本发明涉及一种用于测试口腔恶臭,特别是咖啡口服恶臭的方法。 本文描述了用于测试口腔护理组合物降低口腔恶臭的功效的方法,该方法包括以下步骤:a)用口腔护理组合物清洁至少一部分口腔; b)从清洁的口腔测试呼出的呼吸样品,以提供表示在呼出气中检测到的至少一种口腔恶臭成分的量的测试结果; c)将口腔暴露于包含或能够形成至少一种口腔恶臭成分的口腔恶臭物质; 以及d)从口腔测试呼出的呼吸样品,以提供表示在呼出气中检测到的至少一种口腔恶臭成分的量的测试结果。
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公开(公告)号:US08895929B2
公开(公告)日:2014-11-25
申请号:US14322897
申请日:2014-07-02
Applicant: Colgate-Palmolive Company
Inventor: Jennifer Gronlund , Guofeng Xu , Deborah A. Peru , Ravi Subramanyam
CPC classification number: G01N21/33 , A46B15/0002 , A46B15/0004 , A46B15/0034 , A46B2200/1066 , A61B5/0075 , A61B5/4547 , A61B5/4552 , A61B5/6887 , G01N21/359
Abstract: Improved analytical, diagnostic, monitoring, and other methods (and their associated devices) for evaluating the extent of deposition of an agent onto a substrate are described. Exemplary methods may be used in the in the monitoring of the dental health of patients or in the fast, efficient screening and/or characterization of formulations in terms of their use for depositing oral actives onto tooth surfaces. The methods involve the direct or in situ analysis of substrates, onto which agents are deposited, using Near-IR spectroscopy and/or UV spectroscopy.
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公开(公告)号:US20150265183A1
公开(公告)日:2015-09-24
申请号:US14441184
申请日:2012-12-21
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid
IPC: A61B5/08 , A61B10/00 , G01N33/497 , A61Q11/00 , A61K8/55
CPC classification number: A61B5/08 , A61B5/082 , A61B10/00 , A61B2010/0087 , A61K8/33 , A61K8/35 , A61K8/55 , A61Q11/00 , G01N33/497 , G01N2033/4975 , Y10T436/182
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.
Abstract translation: 本发明涉及一种口服恶臭的检测方法,特别是洋葱和大蒜口服恶臭。 本文描述了用于测试口腔护理组合物降低口腔恶臭的功效的方法,该方法包括以下步骤:a)用口腔护理组合物清洁至少一部分口腔; b)从清洁的口腔测试呼出呼吸的第一样本,以提供表示在呼出气中检测到的第一量的至少一种口腔恶臭成分的第一测试结果; c)将口腔暴露于包含或能够形成至少一种口腔恶臭成分的口腔恶臭物质; 以及d)从所述口腔测试第二呼出呼气样品,以提供第二测试结果,所述第二测试结果代表在所述呼出气体中检测到的所述至少一种口腔恶臭成分的第二量。
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公开(公告)号:US20140312232A1
公开(公告)日:2014-10-23
申请号:US14322897
申请日:2014-07-02
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: Jennifer Gronlund , Guofeng Xu , Deborah A. Peru , Ravi Subramanyam
CPC classification number: G01N21/33 , A46B15/0002 , A46B15/0004 , A46B15/0034 , A46B2200/1066 , A61B5/0075 , A61B5/4547 , A61B5/4552 , A61B5/6887 , G01N21/359
Abstract: Improved analytical, diagnostic, monitoring, and other methods (and their associated devices) for evaluating the extent of deposition of an agent onto a substrate are described. Exemplary methods may be used in the in the monitoring of the dental health of patients or in the fast, efficient screening and/or characterization of formulations in terms of their use for depositing oral actives onto tooth surfaces. The methods involve the direct or in situ analysis of substrates, onto which agents are deposited, using Near-IR spectroscopy and/or UV spectroscopy.
Abstract translation: 描述了用于评估试剂沉积到基底上的程度的改进的分析,诊断,监测和其它方法(及其相关的装置)。 就口服活性成分在牙齿表面上的使用而言,可以使用示例性的方法来监测患者的牙齿健康状况,或用于快速有效地筛选和/或表征制剂。 该方法涉及使用近红外光谱和/或紫外光谱直接或原位分析沉积有试剂的底物。
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公开(公告)号:US09823236B2
公开(公告)日:2017-11-21
申请号:US14441962
申请日:2012-12-21
Applicant: Colgate-Palmolive Company
Inventor: Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid , Ariel Haskel
CPC classification number: G01N33/497 , A61K8/24 , A61K8/33 , A61K8/35 , A61K8/4913 , A61K8/4973 , A61K2800/591 , A61Q11/00
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from coffee. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a sample of exhaled breath from the cleaned oral cavity to provide a test result representing a amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a sample of exhaled breath from the oral cavity to provide a test result representing an amount of the at least one oral malodor component detected in the exhaled breath.
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