COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS OF THE BOWEL
    1.
    发明申请
    COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS OF THE BOWEL 有权
    用于处理BOWEL的炎症条件的组合物和方法

    公开(公告)号:US20100035852A1

    公开(公告)日:2010-02-11

    申请号:US12536390

    申请日:2009-08-05

    IPC分类号: A61K31/56 C12Q1/02

    摘要: The present invention provides compositions and methods for treating inflammatory conditions (e.g., of the bowel). In particular, the present invention provides methods of treating (e.g., therapeutically and/or prophylactically treating) inflammatory conditions (e.g., of the bowel), compositions useful for such methods (e.g., antagonists and/or inhibitors of angiotensin II (AngII) receptor Type 1a (AT1a)), and methods of identifying, characterizing and/or optimizing such compositions. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine) and research applications.

    摘要翻译: 本发明提供用于治疗炎性病症(例如肠)的组合物和方法。 特别地,本发明提供了治疗(例如,治疗和/或预防性治疗)炎性病症(例如肠)的方法,用于这些方法的组合物(例如拮抗剂和/或血管紧张素II(AngII)受体的抑制剂) 类型1a(AT1a))以及鉴定,表征和/或优化这些组合物的方法。 本发明的组合物和方法尤其用于临床(例如治疗和预防性药物)和研究应用。

    Compositions and methods for treating inflammatory conditions of the bowel
    2.
    发明授权
    Compositions and methods for treating inflammatory conditions of the bowel 有权
    用于治疗肠道炎症状况的组合物和方法

    公开(公告)号:US08293776B2

    公开(公告)日:2012-10-23

    申请号:US12536390

    申请日:2009-08-05

    IPC分类号: A61K31/41

    摘要: The present invention provides compositions and methods for treating inflammatory conditions (e.g., of the bowel). In particular, the present invention provides methods of treating (e.g., therapeutically and/or prophylactically treating) inflammatory conditions (e.g., of the bowel), compositions useful for such methods (e.g., antagonists and/or inhibitors of angiotensin II (AngII) receptor Type 1a (AT1a)), and methods of identifying, characterizing and/or optimizing such compositions. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine) and research applications.

    摘要翻译: 本发明提供用于治疗炎性病症(例如肠)的组合物和方法。 特别地,本发明提供了治疗(例如,治疗和/或预防性治疗)炎性病症(例如肠)的方法,用于这些方法的组合物(例如拮抗剂和/或血管紧张素II(AngII)受体的抑制剂) 类型1a(AT1a))以及鉴定,表征和/或优化这些组合物的方法。 本发明的组合物和方法尤其用于临床(例如治疗和预防性药物)和研究应用。

    GUIDE ASSEMBLY FOR INTRAMEDULLARY FIXATION AND METHOD OF USING THE SAME
    5.
    发明申请
    GUIDE ASSEMBLY FOR INTRAMEDULLARY FIXATION AND METHOD OF USING THE SAME 有权
    用于内插式固定的指导装置及其使用方法

    公开(公告)号:US20090157077A1

    公开(公告)日:2009-06-18

    申请号:US11957742

    申请日:2007-12-17

    IPC分类号: A61B17/58 A61B17/56

    摘要: A guide assembly for facilitating placement of a fixation member within a medullary canal of a radius is provided. According to one embodiment, a guide assembly includes a guide fastener configured to attach to a fixation member and a guide member configured to receive the guide fastener such that the guide member is secured to the fixation member. The guide assembly also includes an interchangeable distal guide member configured to engage and be disengaged from the guide member. The distal guide member defines a plurality of fastener guide openings for guiding respective fasteners through a plurality of fastener openings defined in the fixation member.

    摘要翻译: 提供了一种用于促进将固定构件放置在半径的髓质管内的引导组件。 根据一个实施例,引导组件包括构造成附接到固定构件的引导紧固件和构造成接收引导紧固件的引导构件,使得引导构件固定到固定构件。 引导组件还包括可互换的远侧引导构件,其构造成与引导构件接合并脱离。 远侧引导构件限定多个紧固件引导开口,用于通过限定在固定构件中的多个紧固件开口引导相应的紧固件。

    METHOD AND APPARATUS FOR CLEANING THE CUTTING SYSTEM OF AN ELECTRIC SHAVER
    6.
    发明申请
    METHOD AND APPARATUS FOR CLEANING THE CUTTING SYSTEM OF AN ELECTRIC SHAVER 失效
    清洁电动剃须刀切割系统的方法和装置

    公开(公告)号:US20080210271A1

    公开(公告)日:2008-09-04

    申请号:US12030027

    申请日:2008-02-12

    CPC分类号: A45D27/46 B08B3/02

    摘要: By providing a shaver receiving and supporting housing which is constructed for enabling cleaning fluid to be delivered directly to the interior of a shaver in a highly efficient manner, a fully integrated shaving cleaning system is realized which is capable of providing automated cleaning of the shaver in an efficient and effective manner. In accordance with the present invention, the cleaning fluid if forced through portals formed in the shaver for enabling the fluid to be forcibly delivered directly into the hair pocket of the shaver, thereby enabling the surfaces of the hair pocket, the cutting foils, and the cutting blades to be completely and thoroughly cleaned, with the fluid draining out of the shaver through the cutting foils. In addition, the present invention is constructed for thoroughly and completely cleaning both rotary shavers and foil shavers.

    摘要翻译: 通过提供一种剃须刀接收和支撑壳体,其被构造用于使清洁流体能够以高效的方式直接输送到剃须刀的内部,实现了完全集成的剃刮清洁系统,其能够提供剃须刀的自动清洁 高效有效的方式。 根据本发明,如果强制通过形成在剃须刀中的入口的清洁流体,以使流体能够被强制地输送到剃须刀的毛发袋中,从而使得头发袋,切割箔和 切割刀片被完全和彻底地清洁,液体通过切割箔从剃须刀排出。 此外,本发明构造成用于彻底且全面地清洁旋转剃须刀和箔片剃须刀。

    System for suture anchor placement
    7.
    发明授权
    System for suture anchor placement 失效
    缝合锚定位系统

    公开(公告)号:US5948000A

    公开(公告)日:1999-09-07

    申请号:US919900

    申请日:1997-08-28

    摘要: A system for suture anchor placement includes an apparatus having a handle portion and an operating portion. The handle portion includes a spring, a needle park, and a member for releasably holding a length of the suture. The operating portion includes a sheath tube and a plunger rod slidably disposed within the bore of the sheath tube. The plunger rod is fixedly mounted at its proximal end to the handle. The suture anchor is releasably engaged to the distal end portion of the plunger rod. The sheath tube is mounted to the handle and movable with respect to the handle between a distal position and a proximal position, the sheath tube being resiliently biased to the distal position by the spring and movable to the proximal position in response to proximally directed force of sufficient magnitude applied to the distal end of the sheath tube. The sheath tube has a portion with an outer diameter greater than the diameter of the hole in the bone such that when the installation tool is pressed toward the bone, the sheath tube retracts into the handle and the suture anchor is advanced into a hole previously made in the bone. The suture, initially held in a taut configuration, is released in response to movement of the sheath tube to its proximal position.

    摘要翻译: 用于缝合锚定位置的系统包括具有手柄部分和操作部分的装置。 手柄部分包括弹簧,针头公园和用于可释放地保持一定长度的缝合线的构件。 操作部分包括护套管和可滑动地设置在护套管的孔内的柱塞杆。 柱塞杆的近端固定地安装在手柄上。 缝合锚固件可释放地接合到柱塞杆的远端部分。 护套管安装到手柄并且可相对于手柄在远端位置和近端位置之间移动,护套管通过弹簧弹性地偏压到远端位置,并响应于近端位置而运动到近端位置 足够的尺寸施加到护套管的远端。 护套管具有外径大于骨中孔的直径的部分,使得当安装工具被压向骨骼时,护套管缩回到手柄中,并且缝线锚固件进入预先制成的孔 在骨头里 最初保持在紧固结构中的缝合线响应于护套管到其近端位置的运动被释放。