公开(公告)号：US11366125B2

公开(公告)日：2022-06-21

申请号：US16603119

申请日：2017-07-18

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Jeffrey A. Nielsen ,  Christie Dudenhoefer

IPC: G01N1/00 ,  G01N35/00 ,  G01N35/10

Abstract: Examples described herein also provide a substrate conveyance system. The substrate conveyance system may include a conveyor surface to convey a number of substrates, and a number of apertures defined in the conveyor surface between the substrates as positioned on the conveyor surface. The location of the apertures is based on a location at which at least one reagent module dispenses a reagent.

公开(公告)号：US20220146544A1

公开(公告)日：2022-05-12

申请号：US17414031

申请日：2019-07-31

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Diane R. Hammerstad ,  Jeffrey A. Nielsen ,  Christie Dudenhoefer ,  Matthew Smith

IPC: G01N35/10 ,  B01L3/02

Abstract: Aspects of the present disclosure relate to evaporation compensation in fluidic devices. An example apparatus for evaporation compensation includes an assessment circuit to determine an amount of evaporation of a volume dispensed in a microwell of a fluidic device. The amount of evaporation may be determined based on the volume in the microwell, and an amount of time after dispensing the volume in the microwell. A compensation circuit may determine, based on the amount of evaporation, a compensation factor for the microwell including an amount of a normalizing fluid to compensate for the amount of evaporation. The compensation circuit may also create a normalization profile for the fluidic device, including an association between the fluidic device and the compensation factor. A dispensing circuit may dispense the normalizing fluid in the microwell according to the normalization profile.

公开(公告)号：US11203017B2

公开(公告)日：2021-12-21

申请号：US16099668

申请日：2016-07-26

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Jeffrey A Nielsen ,  Manish Giri ,  Chantelle Domingue ,  Kenneth Ward ,  Christie Dudenhoefer ,  Matthew David Smith ,  Joshua M. Yu ,  Diane R. Hammerstad ,  Hilary Ely

IPC: B01L3/00 ,  B01L3/02 ,  G01N15/10 ,  G01N35/10 ,  G01N15/14

Abstract: According to an example, a microfluidic apparatus may include a channel, a foyer, in which the foyer is in fluid communication with the channel and in which the channel has a smaller width than the foyer, a sensor to sense a property of a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to determine whether the sensed property of the fluid meets a predetermined condition and to perform a predefined action in response to the sensed property of the fluid meeting the predetermined condition.

公开(公告)号：USD917066S1

公开(公告)日：2021-04-20

申请号：US29689292

申请日：2019-04-29

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Designer： Dennis R. Esterberg ,  Vignesh Kannan ,  Kenneth Ward ,  Christie Dudenhoefer

公开(公告)号：US10029259B2

公开(公告)日：2018-07-24

申请号：US15650599

申请日：2017-07-14

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Dennis R Esterberg ,  Frank D Derryberry ,  Richard W Seaver ,  Christie Dudenhoefer

IPC: B01L3/00 ,  B41J2/175

Abstract: A slot extender includes a reservoir. The reservoir includes a reservoir floor defining a drain opening, a continuous reservoir sidewall extending from the reservoir floor, and a concave fillet running along at least a portion where the reservoir sidewall joins the reservoir floor. The concave fillet has a variable radius.

公开(公告)号：US12270820B2

公开(公告)日：2025-04-08

申请号：US17044996

申请日：2018-06-04

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Jeffrey A. Nielsen ,  Christie Dudenhoefer ,  Debora J. Thomas ,  Roberto A Pugliese ,  Diane R. Hammerstad

IPC: G01N35/10 ,  B01L3/00 ,  B01L3/02

Abstract: In one example in accordance with the present disclosure, a fluidic die is described. The fluidic die includes a plurality of ejection subassemblies. Each ejection subassembly includes an ejection chamber to hold a volume of fluid and an opening through which the volume of fluid is ejected via a fluid actuator. A pitch of the ejection subassemblies aligns with a spatial arrangement of nanowells in an array of nanowells on a substrate.

公开(公告)号：US11383230B2

公开(公告)日：2022-07-12

申请号：US16085253

申请日：2016-03-31

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Jeffrey A. Nielsen ,  Michael W. Cumbie ,  Devin Alexander Mourey ,  Silam J. Choy ,  Kenneth Ward ,  Christie Dudenhoefer

IPC: B01L3/02

Abstract: A digital dispense apparatus includes at least one fluid dispense device, at least one reservoir fluidically connected to the at least one fluid dispense device, a monolithic carrier structure carrying the at least one fluid dispense device and reservoir, the monolithic carrier forming fluid routing between the reservoir and the fluid dispense device.

公开(公告)号：US20210011043A1

公开(公告)日：2021-01-14

申请号：US16500362

申请日：2017-07-18

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Suzanne Mirashrafi ,  Christie Dudenhoefer ,  Heather B. Louderback ,  Craig Olbrich ,  Dennis R. Esterberg ,  Jeffrey A. Nielsen

IPC: G01N35/10 ,  G01N35/00 ,  G01N35/02

Abstract: A reagent substrate may include a reagent sample deposition area on which a sample of a reagent is deposited, and a number of diagnostic regions on which a diagnostic sample of the reagent is deposited for verification of deposition of the diagnostic sample. A reagent dispensing system may include a conveyor surface to convey a number of substrates, at least one reagent module located in-line with respect to the conveyor surface where the reagent module includes at least one reagent dispensing device to dispense a reagent on the substrates, and at least one optical sensor to verify the dispensing of the reagent at a number of diagnostic regions of the substrate.

公开(公告)号：US20180222109A1

公开(公告)日：2018-08-09

申请号：US15748846

申请日：2015-10-20

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： David H. Ochs ,  Joshua M. Yu ,  Jeffrey A. Nielsen ,  Kenneth Ward ,  Christie Dudenhoefer

IPC: B29C64/112 ,  B29C64/386 ,  B29C64/40 ,  B29C64/188

CPC classification number: B29C64/112 ,  B29C64/188 ,  B29C64/245 ,  B29C64/386 ,  B29C64/40 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y50/02

Abstract: Systems, methods, and computer readable medium to provide patterned layer deposition of liquid types to a plate surface in layers organized in layouts with sites of patterns aligned to a plate origin of the plate surface. At least one layer includes a layout defining a geometric layout of the plate surface.

公开(公告)号：US11774463B2

公开(公告)日：2023-10-03

申请号：US16770198

申请日：2018-01-26

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Dennis R. Esterberg ,  Christie Dudenhoefer

IPC: G01N35/10 ,  G01N35/00 ,  B01L9/00

CPC classification number: G01N35/109 ,  B01L9/52 ,  G01N35/00029 ,  G01N35/1011 ,  B01L9/523 ,  B01L9/527 ,  B01L2200/025 ,  B01L2300/0816 ,  B01L2300/0822 ,  B01L2300/0829 ,  G01N2035/00138 ,  G01N2035/1039

Abstract: In one example, dispenser stages described herein may include a dispenser platform comprising: a stage coupled to a rail system to move the stage in a first plane and a second plane, an alignment feature coupled to the stage to align a substrate nest coupled to the stage with a dispenser positioned above the stage, and a releasable fastener to couple the substrate nest to the stage.