公开(公告)号：US20070128686A1

公开(公告)日：2007-06-07

申请号：US11598848

申请日：2006-11-14

申请人： Gaoshan Jing ,  Jian Zhang ,  Jing Cheng

发明人： Gaoshan Jing ,  Jian Zhang ,  Jing Cheng

IPC分类号： C12Q1/04 ,  G01N33/48 ,  C12N5/04 ,  C12N5/06 ,  C12N1/20

CPC分类号： B03C5/005

摘要： This invention relates generally to the field of cell separation or isolation. In particular, the invention provides a method for separating cells, which method comprises: a) selectively staining cells to be separated with a dye so that there is a sufficient difference in a separable property of differentially stained cells; and b) separating said differentially stained cells via said separable property. Preferably, the separable property is dielectrophoretic property of the differentially stained cells and the differentially stained cells are separated or isolated via dielectrophoresis. Methods for separating various types of cells in blood samples are also provided. Centrifuge tubes useful in density gradient centrifugation and dielectrophoresis isolation devices useful for separating or isolating various types of cells are further provided.

摘要翻译： 本发明一般涉及细胞分离或分离领域。 特别地，本发明提供了一种分离细胞的方法，该方法包括：a）用染料选择性染色待分离的细胞，使得差异染色细胞的可分离性有足够的差异; 和b）通过所述可分离性质分离所述差异染色的细胞。 优选地，可分离性质是差异染色的细胞的介电电泳性质，并且通过介电电泳分离或分离差异染色的细胞。 还提供了用于分离血液样品中各种细胞的方法。 进一步提供了可用于分离或分离各种类型细胞的密度梯度离心和介电电泳分离装置的离心管。

公开(公告)号：US20070009081A1

公开(公告)日：2007-01-11

申请号：US11441281

申请日：2006-05-25

申请人： Otto Zhou ,  Jianping Lu ,  Yueh Lee ,  Weili Lin ,  Yuan Cheng ,  Jian Zhang

发明人： Otto Zhou ,  Jianping Lu ,  Yueh Lee ,  Weili Lin ,  Yuan Cheng ,  Jian Zhang

IPC分类号： A61B6/00 ,  G01N23/00 ,  G21K1/12 ,  H05G1/60

CPC分类号： B82Y10/00 ,  A61B6/032 ,  A61B6/4028 ,  A61B6/508 ,  A61B6/541 ,  G01N23/046 ,  G01N2223/316 ,  G01N2223/419 ,  G01N2223/612 ,  H01J35/065 ,  H01J2201/30469 ,  H01J2235/068

摘要： Computed tomography device comprising an x-ray source and an x-ray detecting unit. The x-ray source comprises a cathode with a plurality of individually programmable electron emitting units that each emit an electron upon an application of an electric field, an anode target that emits an x-ray upon impact by the emitted electron, and a collimator. Each electron emitting unit includes an electron field emitting material. The electron field emitting material includes a nanostructured material or a plurality of nanotubes or a plurality of nanowires. Computed tomography methods are also provided.

摘要翻译： 计算机断层摄影装置，包括x射线源和x射线检测单元。 x射线源包括具有多个单独可编程的电子发射单元的阴极，每个单独可编程的电子发射单元在施加电场时发射电子，在被所发射的电子撞击时发射x射线的阳极靶和准直器。 每个电子发射单元包括电子场发射材料。 电子场发射材料包括纳米结构材料或多个纳米管或多个纳米线。 还提供了计算机断层扫描方法。

公开(公告)号：US07153648B2

公开(公告)日：2006-12-26

申请号：US10103581

申请日：2002-03-20

申请人： Gaoshan Jing ,  Jian Zhang ,  Jing Cheng

发明人： Gaoshan Jing ,  Jian Zhang ,  Jing Cheng

IPC分类号： A01N1/02

CPC分类号： B03C5/005

摘要： This invention relates generally to the field of cell separation or isolation. In particular, the invention provides a method for separating cells, which method comprises: a) selectively staining cells to be separated with a dye so that there is a sufficient difference in a separable property of differentially stained cells; and b) separating said differentially stained cells via said separable property. Preferably, the separable property is dielectrophoretic property of the differentially stained cells and the differentially stained cells are separated or isolated via dielectrophoresis. Methods for separating various types of cells in blood samples are also provided. Centrifuge tubes useful in density gradient centrifugation and dielectrophoresis isolation devices useful for separating or isolating various types of cells are further provided.

摘要翻译： 本发明一般涉及细胞分离或分离领域。 特别地，本发明提供了一种分离细胞的方法，该方法包括：a）用染料选择性染色待分离的细胞，使得差异染色细胞的可分离性有充分差异; 和b）通过所述可分离性质分离所述差异染色的细胞。 优选地，可分离性质是差异染色的细胞的介电电泳性质，并且通过介电电泳分离或分离差异染色的细胞。 还提供了用于分离血液样品中各种细胞的方法。 进一步提供了可用于分离或分离各种类型细胞的密度梯度离心和介电电泳分离装置的离心管。

公开(公告)号：US20060242718A1

公开(公告)日：2006-10-26

申请号：US11400964

申请日：2006-04-10

申请人： Tracy Willson ,  Richard Simpson ,  Alison Farley ,  Sandra Nicholson ,  Jian Zhang ,  Manuel Baca ,  Nicos Nicola ,  Douglas Hilton ,  Warren Alexander ,  Donald Metcalf

发明人： Tracy Willson ,  Richard Simpson ,  Alison Farley ,  Sandra Nicholson ,  Jian Zhang ,  Manuel Baca ,  Nicos Nicola ,  Douglas Hilton ,  Warren Alexander ,  Donald Metcalf

IPC分类号： A01K67/00 ,  A61K38/22

CPC分类号： C07K14/4703 ,  A01K2217/05 ,  A61K38/00

摘要： The present invention relates generally to amino acid sequences obtainable from SOCS proteins and which are capable of interacting with intracellular molecules. The present invention further relates to nucleic acid molecules encoding said amino acid sequences. The amino acid sequences and the nucleic acid molecules encoding same of the present invention are useful in modulating degradation of proteinaceous molecules such as but not limited to SOCS proteins and proteinaceous molecules associate therewith. The present invention provides a mechanism for modulating cytokine or cytokine-like molecule signaling by modulating the degradation of activated signal transduction molecules or their negative regulators, i.e. the SOCS proteins.

摘要翻译： 本发明一般涉及可从SOCS蛋白获得并且能够与细胞内分子相互作用的氨基酸序列。 本发明还涉及编码所述氨基酸序列的核酸分子。 编码本发明的氨基酸序列和核酸分子可用于调节蛋白质分子的降解，例如但不限于与其缔合的SOCS蛋白和蛋白质分子。 本发明提供了通过调节活化的信号转导分子或其负调节物（即SOCS蛋白）的降解来调节细胞因子或细胞因子样分子信号传导的机制。

公开(公告)号：US07021993B2

公开(公告)日：2006-04-04

申请号：US10198841

申请日：2002-07-19

申请人： Jian Zhang ,  Fred Sun ,  Shumin Wang ,  Isaac K. Cherian ,  Eric H. Klingenberg

发明人： Jian Zhang ,  Fred Sun ,  Shumin Wang ,  Isaac K. Cherian ,  Eric H. Klingenberg

IPC分类号： B24B1/00

CPC分类号： C09K3/1463 ,  B24B37/00 ,  H01L21/3212

摘要： The invention provides a method of polishing a substrate comprising (i) contacting a substrate with a polishing system comprising (a) an abrasive, a polishing pad, a means for oxidizing a substrate, or any combination thereof, (b) a conducting polymer having an electrical conductivity of about 10−10 S/cm to about 106 S/cm, and (c) a liquid carrier, and (ii) abrading or removing at least a portion of the substrate to polish the substrate.

摘要翻译： 本发明提供一种抛光衬底的方法，其包括（i）使衬底与抛光系统接触，所述抛光系统包括（a）研磨剂，抛光垫，用于氧化衬底的装置或其任何组合，（b）导电聚合物，其具有 约10 -6 S / cm至约10 -6 S / cm的电导率，和（c）液体载体，和（ii）至少研磨或除去 衬底的一部分以抛光衬底。

公开(公告)号：US20060068564A1

公开(公告)日：2006-03-30

申请号：US11273827

申请日：2005-11-14

申请人： Kui Yao ,  Xujiang He ,  Jian Zhang ,  Santiranjan Shannigrahi

发明人： Kui Yao ,  Xujiang He ,  Jian Zhang ,  Santiranjan Shannigrahi

IPC分类号： H01L21/30 ,  H01L21/20

CPC分类号： B81C1/00587 ,  B81B3/0035

摘要： A method for fabricating a MEMS device comprises providing a substrate having a back side, a front side opposite to the back side and a periphery portion. A desired microstructure is formed on the back side of the substrate. The substrate is then supported for rotation. A precursor solution is deposited on the front side of the substrate during rotation so that a thin film layer may be formed thereon. During formation of the thin film layer, the substrate is supported and rotated that the microstructure formed on the back side is protected.

公开(公告)号：US20060048237A1

公开(公告)日：2006-03-02

申请号：US11211804

申请日：2005-08-25

申请人： Lin Luo ,  Jian Zhang ,  Rong Yan ,  Ling Shao

发明人： Lin Luo ,  Jian Zhang ,  Rong Yan ,  Ling Shao

IPC分类号： H04N7/16

CPC分类号： H04L63/0428 ,  H04L2463/103 ,  H04N21/2541 ,  H04N21/41407 ,  H04N21/44236 ,  H04N21/6131 ,  H04N21/8358

摘要： Provides methods for tracing and identifying a piracy in a wireless rights management system, wherein the content provider allow the protected digital content to be super-distributed, when unauthorized holding a pirated copy of the protected digital content is detected, based on the gateway controlling ability of the wireless operator within the wireless digital rights management system, a specific fingerprint is embedded in or removed from the protected digital content so as to trace the suspected persons and further identify the pirate. The fingerprint is related to information of a suspected person holding the protected digital content without authorization. A process of screening singles out highly suspected persons. Therefore the operator can determine whether the suspected person is a real pirate by comparing the similarity of the pirated version of content and the version held by the suspected person, and the exact tracing and identifying is achieved.

摘要翻译： 提供了在无线权限管理系统中跟踪和识别盗版的方法，其中，当未经授权的情况下，基于所述网关控制能力检测到未经授权的方式检测到受保护的数字内容的盗版副本时，所述内容提供商允许所述受保护的数字内容被超分散 无线数字版权管理系统内的无线运营商，将特定的指纹嵌入到受保护的数字内容中或从受保护的数字内容中移除，以便跟踪可疑的人并进一步识别盗版者。 该指纹与未经授权持有受保护的数字内容的怀疑人员的信息相关。 筛选高度怀疑人士的过程。 因此，运营商可以通过比较盗版内容与嫌疑人所持有的版本的相似性来确定被怀疑的人是否是真正的盗版者，并且实现了准确的跟踪和识别。

公开(公告)号：US20060030158A1

公开(公告)日：2006-02-09

申请号：US11235765

申请日：2005-09-26

申请人： Phillip Carter ,  Jian Zhang ,  Steven Grumbine ,  Francesco Rege Thesauro

发明人： Phillip Carter ,  Jian Zhang ,  Steven Grumbine ,  Francesco Rege Thesauro

IPC分类号： B24B1/00 ,  C09K3/14 ,  H01L21/461

CPC分类号： H01L21/3212 ,  B24B37/044 ,  C09G1/02 ,  C09K3/1463 ,  C23F3/04 ,  C23F3/06

摘要： A composition suitable for tantalum chemical-mechanical polishing (CMP) comprises an abrasive, an organic oxidizer, and a liquid carrier therefor. The organic oxidizer has a standard redox potential (E0) of not more than about 0.5 V relative to a standard hydrogen electrode. The oxidized form comprises at least one pi-conjugated ring, which includes at least one heteroatom directly attached to the ring. The heteroatom can be a N, O, S or a combination thereof. In a method embodiment, a CMP composition comprising an abrasive, and organic oxidizer having an E0 of not more than about 0.7 V relative to a standard hydrogen electrode, and a liquid carrier therefor, is utilized to polish a tantalum-containing surface of a substrate, by abrading the surface of the substrate with the composition, preferably with the aid of a polishing pad.

摘要翻译： 适用于钽化学机械抛光（CMP）的组合物包括研磨剂，有机氧化剂和用于其的液体载体。 有机氧化剂相对于标准氢电极具有不超过约0.5V的标准氧化还原电位（E 0 SUP 0）。 氧化形式包含至少一个π-共轭环，其包括至少一个直接连接在环上的杂原子。 杂原子可以是N，O，S或它们的组合。 在方法实施方案中，使用包含磨料和相对于标准氢电极不超过约0.7V的E 0有机氧化剂的CMP组合物及其液体载体来抛光 通过用组合物研磨基底的表面，优选借助于抛光垫，将基底的含钽表面。

公开(公告)号：US20060014627A1

公开(公告)日：2006-01-19

申请号：US11230950

申请日：2005-09-19

申请人： Jian Zhang ,  Hwey Liow ,  Bo Zhang

发明人： Jian Zhang ,  Hwey Liow ,  Bo Zhang

IPC分类号： C04B35/488

CPC分类号： C04B35/488 ,  B01L3/0275 ,  B25B9/02 ,  B26B13/00 ,  C04B35/117 ,  C04B35/119 ,  C04B35/486 ,  C04B35/4885 ,  C04B35/63 ,  C04B35/632 ,  C04B35/634 ,  C04B35/63416 ,  C04B2235/3225 ,  C04B2235/3232 ,  C04B2235/3241 ,  C04B2235/3246 ,  C04B2235/3272 ,  C04B2235/449 ,  C04B2235/6022 ,  C04B2235/652 ,  C04B2235/6581 ,  C04B2235/6582 ,  C04B2235/80 ,  C04B2235/96

摘要： The invention provides partially stabilised zirconia and alumina based electro-static dissipative or ESD ceramic compositions. The proposed ceramic compositions include specific amounts of dopants comprising one or more metal oxides selected from iron oxide, chromium oxide and titanium oxide. The proposed ESD ceramic materials are made into useful industrial products by injection moulding and sintering technology. A novel binder system may optionally be used to make injection mouldable feedstock. Useful products produced by the invention include, for example, ESD ceramic tweezers tips, ESD ceramic dispensing needles, ESD ceramic scissors and blades and ESD ceramic wire bonding capillaries which retain their ESD properties at relatively low temperatures, for example, service temperatures from 25 to 500° C.

摘要翻译： 本发明提供部分稳定的氧化锆和氧化铝基静电消散或ESD陶瓷组合物。 所提出的陶瓷组合物包括特定量的包含一种或多种选自氧化铁，氧化铬和氧化钛的金属氧化物的掺杂剂。 所提出的ESD陶瓷材料通过注塑和烧结技术制成有用的工业产品。 可以任选地使用新的粘合剂体系来制备注射成型的原料。 本发明生产的有用的产品包括例如ESD陶瓷镊子尖端，ESD陶瓷分配针，ESD陶瓷剪刀和刀片以及在相对低的温度下保持其ESD特性的ESD陶瓷丝焊接毛细管，例如从25到 500°C

公开(公告)号：US20050255685A1

公开(公告)日：2005-11-17

申请号：US11067597

申请日：2005-02-26

申请人： Jian Zhang

发明人： Jian Zhang

IPC分类号： B23K1/008 ,  B23K3/06 ,  H01L21/44 ,  H01L21/60

CPC分类号： H01L24/11 ,  B23K1/008 ,  B23K3/0638 ,  B23K2101/40 ,  H01L2224/13099 ,  H01L2924/01005 ,  H01L2924/01006 ,  H01L2924/01027 ,  H01L2924/01059 ,  H01L2924/0106 ,  H01L2924/01082 ,  H01L2924/01322 ,  H01L2924/014 ,  H01L2924/14

摘要： A process for the production of a void-free semiconductor wafer for the electronics industry, comprising the steps of: applying a coating of a solder paste to a semiconductor wafer through a photoresist film; heating and applying a vacuum to the wafer in a reflow furnace with a controlled formic acid vapor ambient to for a first reflow to remove the flux and form void free solder bumps on the wafer; processing the wafer to remove the photoresist film; heating the wafer in a reflow furnace with a controlled formic acid vapor ambient for a second reflow to remove surface oxides from the wafer and to form the solder into final void free metal solder bumps.

摘要翻译： 一种用于生产用于电子工业的无空隙半导体晶片的方法，包括以下步骤：通过光致抗蚀剂膜将焊膏的涂层施加到半导体晶片; 在具有受控甲酸蒸汽环境的回流炉中对晶片加热并施加真空，以进行第一回流以去除焊剂并在晶片上形成无空隙的焊料凸块; 处理晶片以除去光致抗蚀剂膜; 在具有控制的甲酸蒸汽环境的回流炉中加热晶片以进行第二回流以从晶片去除表面氧化物，并将焊料形成最终的无空隙金属焊料凸块。