公开(公告)号：US10001363B2

公开(公告)日：2018-06-19

申请号：US15385886

申请日：2016-12-21

Applicant: Korea Basic Science Institute

Inventor： Kye Sung Lee ,  Gun Hee Kim ,  Hwan Hur ,  I Jong Kim ,  Ki Soo Chang

IPC: G01B9/02

CPC classification number: G01B9/02091 ,  G01B9/02007 ,  G01B9/02023 ,  G01B9/02044 ,  G01B9/02054 ,  G01B9/02057 ,  G01B2290/30

Abstract: Provided is a common-path optical fiber-based handheld parallel optical coherence tomography (OCT) apparatus, including a probe configured to receive the light from a broadband light source and illuminate a measurement target, wherein the probe may include an inner space through which the light passes, a collimator configured to collimate the light incident to the inner space, a diffraction grating configured to diffract the light having passed through the collimator, a galvanometer scanner configured to reflect the light having passed through the diffraction grating, an objective lens configured to concentrate the reflected light on a focal point, and an interferer configured to acquire an interfered light by reflecting at least a portion of the light having passed through the objective lens.

公开(公告)号：US09933376B2

公开(公告)日：2018-04-03

申请号：US14647772

申请日：2013-11-26

Applicant: Korea Basic Science Institute

Inventor： Ki Soo Chang ,  Seon Young Ryu ,  Woo June Choi ,  Geon Hee Kim

IPC: G01N25/72 ,  H01L21/66

CPC classification number: G01N25/72 ,  H01L22/12

Abstract: The present invention provides a method for analyzing defects by using heat distribution measurement, comprising: a sample loading unit for loading a sample to check whether or not there is a defect through heat distribution characteristics; a light source for radiating visible light onto the sample; a power supply unit for generating a driving signal in order to periodically heat the sample; a detection unit for detecting reflected light from the surface of the sample; and a signal generator for synchronizing the detection unit with the driving signal of the power supply unit.

公开(公告)号：US20170285011A1

公开(公告)日：2017-10-05

申请号：US15151180

申请日：2016-05-10

Applicant: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY ,  KOREA BASIC SCIENCE INSTITUTE

Inventor： Du Woon KIM ,  Joseph KWON

IPC: G01N33/50 ,  G01N33/569 ,  A61K38/16

CPC classification number: G01N33/5088 ,  A61K38/168 ,  C12Q1/68 ,  G01N33/5091 ,  G01N33/56983 ,  G01N2333/08 ,  G01N2333/4603 ,  Y02A50/463

Abstract: Discloses are a method for detecting Norovirus using a Norovirus animal model, a method for screening an antivial agent against Norovirus, and a composition for neutralizing the infection with an enteric virus, containing concanavalin A as an active ingredient, so that the method for detecting Norovirus can allow the distinction between infectious Norovirus and non-infectious Norovirus, and the composition can neutralize a virus causing food poisoning.

公开(公告)号：US09672303B2

公开(公告)日：2017-06-06

申请号：US13869868

申请日：2013-04-24

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： Yeon Suk Choi ,  Dong Lak Kim

IPC: G01K17/00 ,  G01K1/08 ,  G06F17/50 ,  G06F1/20 ,  G01K7/42

CPC classification number: G06F17/5009 ,  G01K7/425 ,  G06F1/20 ,  G06F1/206

Abstract: The present invention provides a system and method of predicting the initial cooling of a superconducting magnet, which can predict the change in initial cooling temperature of a superconducting magnet when the superconducting magnet is cooled using an ultra-low refrigerator. In the system and method, the change in cooling temperature of a superconducting magnet can be accurately predicted by classifying influence factors related to the cooling of a superconducting magnet into a plurality of control volumes and inducing a governing equation with respect to each of the control volumes. Based on this system and method, the reliability of basic data required to design an apparatus for measuring a high magnetic field for forming an ultralow-temperature environment can be greatly improved.

公开(公告)号：US09575282B2

公开(公告)日：2017-02-21

申请号：US14389443

申请日：2013-09-13

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： Geon Hee Kim ,  Ha Yeong Sung ,  Woo Kang Kim ,  Kye Sung Lee ,  Ki Soo Chang ,  Ki Ju Yee

IPC: G02B7/02 ,  G02B27/56 ,  G02B7/04 ,  G01Q60/22

CPC classification number: G02B7/023 ,  G01Q60/22 ,  G02B7/025 ,  G02B7/04 ,  G02B27/56

Abstract: Provided is an apparatus for fixing a solid immersion lens (SIL) in an optical system. The apparatus includes a first adapter; a second adapter screw-coupled to the inner surface of the first adapter and screw-coupled to the outer surface of a third adapter to pressurize a first O-ring; the third adapter screw-coupled to the inner surfaces of the second adapter and a fourth adapter; the fourth adapter screw-coupled to the outer surface of the third adapter to pressurize a second O-ring; the first and second O-rings elastically fixing an outer surface of a barrel of an infrared ray (IR) objective lens; and an SIL holder mounting the SIL onto the first adapter.

Abstract translation: 提供了一种用于将固体浸没透镜（SIL）固定在光学系统中的装置。 该装置包括第一适配器; 第二适配器，其螺纹联接到所述第一适配器的内表面，并且螺纹连接到第三适配器的外表面以对第一O形环加压; 所述第三适配器螺纹连接到所述第二适配器的内表面和第四适配器; 所述第四适配器螺纹连接到所述第三适配器的外表面以加压第二O形环; 所述第一和第二O形环弹性地固定红外线（IR）物镜的镜筒的外表面; 以及将SIL安装到第一适配器上的SIL保持架。

公开(公告)号：US20150361338A1

公开(公告)日：2015-12-17

申请号：US14761579

申请日：2014-01-15

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： Hyun-Uk LEE ,  Jou-Hahn LEE ,  Eun-Sik PARK

IPC: C09K11/65

CPC classification number: C09K11/65 ,  C01B32/15

Abstract: A method for preparing photoluminescent carbon nanodots includes preparing and drying a sample, ashing the sample, extracting the ashed sample with solvent, filtering the extracted sample, concentrating the filtered sample, dissolving the sample in water, and freeze-drying the dissolved sample. The sample is preferably a food waste residue or animal excrement.

Abstract translation: 制备光致发光碳纳米点的方法包括制备和干燥样品，灰化样品，用溶剂萃取灰分样品，过滤提取的样品，浓缩过滤的样品，将样品溶解在水中，冷冻干燥溶解的样品。 样品优选为食物废物残留物或动物粪便。

公开(公告)号：US20150232946A1

公开(公告)日：2015-08-20

申请号：US14600419

申请日：2015-01-20

Applicant: Korea Basic Science Institute

Inventor： Gun-Hwa Kim ,  Giwon Kim ,  Soohyun Kim ,  Seung II Kim ,  Edmond Changkyun Park

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178

Abstract: The present invention relates to a recurring glioblastoma multiforme marker miRNA for diagnosing recurring glioblastoma multiforme, and more specifically, to a composition for screening the miRNA marker, which is specific to the recurring glioblastoma multiforme and comprises an agent for detecting the presence of the marker, a kit, and to a method for diagnosing the recurring glioblastoma multiforme using same. The method for diagnosing the recurring glioblastoma multiforme by using the recurring glioblastoma multiforme marker miRNA, according to the present invention, provides glioblastoma markers, which can diagnose the occurrence of the recurring glioblastoma multiforme, thereby providing useful material for managing treatment and prognosis of the recurring glioblastoma multiforme. In addition, the diagnosis markers for the recurring glioblastoma multiforme can be used for development and research of an anticancer agent specific to the recurring glioblastoma multiforme.

Abstract translation: 本发明涉及用于诊断多形性复制性成胶质细胞瘤的复发性成胶质细胞瘤多形性标志物miRNA，更具体地，涉及对多发性成胶质细胞瘤特异性的miRNA标志物的筛选用组合物，其包含用于检测标志物存在的试剂， 一种试剂盒，以及使用该方法诊断复发性多形性成胶质细胞瘤的方法。 根据本发明，通过使用复发性成胶质细胞瘤多形性标志物miRNA诊断多形性成胶质细胞瘤的方法提供了可以诊断复发性多形性成胶质细胞瘤的发生的成胶质细胞瘤标志物，从而提供用于治疗复发性成骨细胞瘤的治疗和预后的有用材料 胶质母细胞瘤多形性。 此外，复发性胶质母细胞瘤多形性的诊断标志物可用于对复发性多形性成胶质细胞瘤特异性的抗癌剂的开发和研究。

公开(公告)号：US09058965B2

公开(公告)日：2015-06-16

申请号：US14097848

申请日：2013-12-05

Applicant: Korea Basic Science Institute

Inventor： Mo Yang ,  Seung Yong Kim ,  Hyun Sik Kim

IPC: H01J49/42 ,  H01J49/06

CPC classification number: H01J49/065 ,  H01J49/421 ,  H01J49/424 ,  Y10T29/49826

Abstract: An ion trap mass spectrometer is provided, including: an electron emitter; an ion trap storing ions generated by ionization resulting from an impact with electrons emitted from the electron emitter; a secondary ion filter for blocking out secondary ions generated due to ions selectively released by the ion trap; and a detector detecting ions selectively released from the ion trap, wherein the electron emitter, the ion trap, the secondary ion filter, and the ion detector are arranged on the same axis, so that a pure mass spectrum can be measured by excluding the secondary ions which are causes of background noise signals in the procedure of detection of the ions by the ion trap mass spectrometer.

Abstract translation: 提供了一种离子阱质谱仪，包括：电子发射体; 离子阱，其存储由从电子发射体发射的电子的撞击而产生的离子产生的离子; 用于阻断由离子阱选择性释放的离子产生的二次离子的二次离子过滤器; 以及检测器，其检测离子阱选择性释放的离子，其中电子发射体，离子阱，二次离子过滤器和离子检测器被布置在相同的轴上，使得可以通过排除次级 离子是离子阱质谱仪检测离子的过程中背景噪声信号的原因。

公开(公告)号：US20140343235A1

公开(公告)日：2014-11-20

申请号：US14373706

申请日：2013-03-20

Applicant: Korea Basic Science Institute ,  Taesung Politech Co. Ltd.

Inventor： Euh Duck Jeong ,  Eun Kyung Jang ,  Tae Eun Hong ,  Mi Rang Byeon ,  Jong Pil Kim ,  Jong Seong Bae ,  Jong Sung Jin ,  Hong Dae Jung ,  Su Jong Lee

IPC: C25D5/34 ,  C25D5/48 ,  C08G75/16

CPC classification number: C25D5/34 ,  B29C45/00 ,  B29C45/14311 ,  B29C45/14778 ,  B29K2705/02 ,  C08G75/16 ,  C08G2650/40 ,  C08K3/08 ,  C08L101/00 ,  C09J5/02 ,  C09J2400/163 ,  C09J2400/166 ,  C09J2400/226 ,  C09J2481/006 ,  C23C22/83 ,  C23C2222/20 ,  C25D11/10 ,  C25D11/16 ,  C25D11/18 ,  C08L71/00

Abstract: Disclosed is an aluminum-polymer resin composite. The composite includes i) aluminum and ii) a polymer resin bonded to the aluminum after modification of the aluminum surface with at least one surface modifier selected from the group consisting of sulfur-containing diazole derivatives, sulfur-containing diamine derivatives, sulfur-containing thiol derivatives, sulfur-containing pyrimidine derivatives, and sulfur-containing silane coupling agents. The intensity ratios of C/Al, N/Al, O/Al, Na/Al, Si/Al, and S/Al in the composite are in the range of 9.75×10−6 to 9.5×10−1 at depths of 100 nm to 500 nm, as analyzed by secondary ion mass spectrometry (SIMS). The composite has improved adhesive strength between the metal and the resin while maintaining its tensile strength and air tightness even after thermal shock testing. The composite is produced through various processing steps, including pretreatment, appropriate surface roughening, thermal treatment and surface coating, to enhance the bonding strength between the metal and the resin. The use of compounds containing S, N and Si further increases the bonding strength between the metal and the resin.

Abstract translation: 公开了铝聚合物树脂复合材料。 所述复合材料包括i）铝和ii）在铝表面改性后与至少一种表面改性剂结合到铝上的聚合物树脂，所述表面改性剂选自含硫二唑衍生物，含硫二胺衍生物，含硫硫醇 衍生物，含硫嘧啶衍生物和含硫硅烷偶联剂。 复合材料中C / Al，N / Al，O / Al，Na / Al，Si / Al和S / Al的强度比在深度为9.75×10-6到9.5×10-1的范围内 通过二次离子质谱（SIMS）分析，其为100nm至500nm。 该复合材料在金属和树脂之间具有改善的粘合强度，同时即使在热冲击测试之后也保持其抗拉强度和气密性。 复合材料通过各种加工步骤生产，包括预处理，适当的表面粗糙化，热处理和表面涂层，以增强金属和树脂之间的粘结强度。 使用含有S，N和Si的化合物进一步增加了金属和树脂之间的结合强度。

公开(公告)号：US20140180625A1

公开(公告)日：2014-06-26

申请号：US13869868

申请日：2013-04-24

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： Yeon Suk Choi ,  Dong Lak Kim

IPC: G06F17/50

CPC classification number: G06F17/5009 ,  G01K7/425 ,  G06F1/20 ,  G06F1/206

Abstract: The present invention provides a system and method of predicting the initial cooling of a superconducting magnet, which can predict the change in initial cooling temperature of a superconducting magnet when the superconducting magnet is cooled using an ultra-low refrigerator. In the system and method, the change in cooling temperature of a superconducting magnet can be accurately predicted by classifying influence factors related to the cooling of a superconducting magnet into a plurality of control volumes and inducing a governing equation with respect to each of the control volumes. Based on this system and method, the reliability of basic data required to design an apparatus for measuring a high magnetic field for forming an ultralow-temperature environment can be greatly improved.

Abstract translation: 本发明提供一种预测超导磁体的初始冷却的系统和方法，该超导磁体可以预测超导磁体使用超低温冷藏器冷却时超导磁体的初始冷却温度的变化。 在该系统和方法中，可以通过将与超导磁体的冷却相关的影响因素分类为多个控制体积并且针对每个控制体积引导控制方程，可以准确地预测超导磁体的冷却温度的变化 。 基于该系统和方法，可以大大提高设计用于测量用于形成超低温环境的高磁场的装置所需的基本数据的可靠性。