公开(公告)号：US20080014249A1

公开(公告)日：2008-01-17

申请号：US11901724

申请日：2007-09-17

Applicant: Andrew Heaton ,  Naresh Kumar ,  Graham Kelly ,  Alan Husband

Inventor： Andrew Heaton ,  Naresh Kumar ,  Graham Kelly ,  Alan Husband

IPC: A61K47/00 ,  A61K31/35 ,  A61P29/00 ,  A61K31/355

CPC classification number: C07D311/26 ,  A23L33/10 ,  A23L33/11 ,  A23V2002/00 ,  C07D311/36 ,  C07D311/38 ,  C07D311/58 ,  C07D471/06 ,  A23V2250/2116 ,  A23V2200/30

Abstract: Isoflavone compounds are described and recommended as therapeutic agents. Exemplified and preferred compounds are (a). Indications show compounds have good competitive binding to estrogen receptors. This is exemplified.

Abstract translation: 描述和推荐异黄酮化合物作为治疗剂。 示例性和优选的化合物是（a）。 适应症显示化合物与雌激素受体具有良好的竞争性结合。 这是例证。

公开(公告)号：US20070261107A1

公开(公告)日：2007-11-08

申请号：US11418051

申请日：2006-05-03

Applicant: Raymond Ng ,  Ganesh Kirti ,  Thomas Keefe ,  Naresh Kumar

Inventor： Raymond Ng ,  Ganesh Kirti ,  Thomas Keefe ,  Naresh Kumar

IPC: H04L9/32

CPC classification number: H04L63/062

Abstract: One embodiment of the present invention provides a system that facilitates accessing a credential. During operation, the system receives a request at a credentials-storage framework (CSF) to retrieve the credential. If a target credential store containing the credential is not already connected to the CSF, the system looks up a bootstrap credential for the target credential store in a bootstrap credential store, which contains bootstrap credentials for other credential stores. Next, the system uses this bootstrap credential to connect the CSF to the target credential store. Finally, the system retrieves the credential from the target credential store, and returns the credential to the requestor.

Abstract translation: 本发明的一个实施例提供一种便于访问证书的系统。 在操作期间，系统在凭证存储框架（CSF）处接收请求以检索凭证。 如果包含凭据的目标凭据存储库尚未连接到CSF，则系统将在引导凭证存储中查找目标凭据存储的引导凭据，其中包含其他凭据存储的引导凭据。 接下来，系统使用此引导凭据将CSF连接到目标凭据存储。 最后，系统从目标凭证存储中检索凭证，并将凭证返回给请求者。

公开(公告)号：US20070136819A1

公开(公告)日：2007-06-14

申请号：US11296086

申请日：2005-12-06

Applicant: Raymond Ng ,  Ganesh Kirti ,  Thomas Keefe ,  Naresh Kumar

Inventor： Raymond Ng ,  Ganesh Kirti ,  Thomas Keefe ,  Naresh Kumar

IPC: H04L9/32

CPC classification number: H04L63/08

Abstract: Systems, methods, and machine-readable media are disclosed for providing conditional grants of permission in an externally configured security policy. In one embodiment, a method is provided which comprises reading a condition clause from a grant statement defined in the security policy. The grant statement can cause the granting of permission for a user to access a requested resource. One or more constraints on the grant statement can be determined based on the condition clause. Permission can be granted to access the requested resource based on the one or more constraints.

Abstract translation: 公开了用于在外部配置的安全策略中提供有限许可的系统，方法和机器可读介质。 在一个实施例中，提供了一种方法，其包括从安全策略中定义的授权语句读取条件子句。 授权语句可能导致授予用户访问所请求资源的权限。 授权语句的一个或多个约束可以基于条件子句来确定。 可以授予权限以基于一个或多个约束来访问所请求的资源。

公开(公告)号：US07148355B2

公开(公告)日：2006-12-12

申请号：US10490275

申请日：2002-09-24

Applicant: Purna Chandra Ray ,  Jayachandra Suresh Babu ,  Mohammad Salman ,  Naresh Kumar

Inventor： Purna Chandra Ray ,  Jayachandra Suresh Babu ,  Mohammad Salman ,  Naresh Kumar

IPC: C07D211/32

CPC classification number: C07D295/135

Abstract: The present invention relates to a cost effective and industrially advantageous process for the preparation of repaglinide.

Abstract translation: 本发明涉及用于制备瑞格列奈的成本效益和工业上有利的方法。

公开(公告)号：US07070814B2

公开(公告)日：2006-07-04

申请号：US10386395

申请日：2003-03-11

Applicant: Ghulam Nabi Qazi ,  Kasturi Lal Bedi ,  Rakesh Kamal Johri ,  Manoj Kumar Tikoo ,  Ashok Kumar Tikoo ,  Subhash Chander Sharma ,  Sheikh Tasaduq Absullah ,  Om Parkash Suri ,  Bishan Datt Gupta ,  Krishan Avtar Suri ,  Naresh Kumar Satti ,  Ravi Kant Khajuria ,  Surjit Singh ,  Anamika Khajuria ,  Bal Krishan Kapahi

Inventor： Ghulam Nabi Qazi ,  Kasturi Lal Bedi ,  Rakesh Kamal Johri ,  Manoj Kumar Tikoo ,  Ashok Kumar Tikoo ,  Subhash Chander Sharma ,  Sheikh Tasaduq Absullah ,  Om Parkash Suri ,  Bishan Datt Gupta ,  Krishan Avtar Suri ,  Naresh Kumar Satti ,  Ravi Kant Khajuria ,  Surjit Singh ,  Anamika Khajuria ,  Bal Krishan Kapahi

IPC: A61K35/78

CPC classification number: A61K45/06 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A23L33/175 ,  A61K31/43 ,  A61K31/4453 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/545 ,  A61K31/704 ,  A61K31/7048 ,  A61K33/04 ,  A61K36/185 ,  A61K36/19 ,  A61K36/23 ,  A61K36/28 ,  A61K36/47 ,  A61K36/59 ,  A61K36/67 ,  A61K36/75 ,  A61K36/80 ,  A61K36/81 ,  A61K36/8965 ,  A61K2300/00

Abstract: The present invention relates to a bioenhancing/bioavailability-facilitating composition comprising: an effective amount of an extract and/or at least one bioactive fraction from Cuminum cyminum; one or more additive selected from drugs, nutrients, vitamins, nutraceuticals, herbal drugs/products, micro nutrients, antioxidants along with pharmaceutically acceptable additives/excipient, and optionally, an effective amount of piperine or extract/fraction of piper nigrum or piper longum; and a process for the preparation of such extracts and active fractions from plant Cuminum cyminum.

Abstract translation: 本发明涉及生物增强/生物利用度促进组合物，其包含：有效量的来自孜然的提取物和/或至少一种生物活性级分; 一种或多种选自药物，营养素，维生素，营养品，草药/产品，微量营养素，抗氧化剂以及药学上可接受的添加剂/赋形剂的添加剂，以及任选的有效量的胡椒碱或胡椒或胡椒的提取物/级分; 以及从植物孜然中制备这些提取物和活性级分的方法。

公开(公告)号：US07064220B1

公开(公告)日：2006-06-20

申请号：US09673305

申请日：1999-04-16

Applicant: Roger Read ,  Naresh Kumar

Inventor： Roger Read ,  Naresh Kumar

IPC: C07D307/58 ,  A01N43/08

CPC classification number: C08F20/00 ,  A01N43/08 ,  C07D307/58 ,  C08F24/00

Abstract: The present invention relates to the side chain functionalization of fimbrolides (halogenated 3-alkyl-5-methylene-2(5H)-furanones) and their synthetic analogues, that yields fimbrolides substituted with a halogen, an oxygen or a nitrogen functionality in the alkyl chain, especially fimbrolide alcohols, carboxylate and sulfinate and sulfonate esters, ethers, aldehydes, ketones, acids, amides, nitro derivatives, hydrophobic, hydrophilic and fluorophilic alkyl derivatives and a polymers.

Abstract translation: 本发明涉及福滨洛尔（卤代3-烷基-5-亚甲基-2（5H） - 呋喃酮）及其合成类似物的侧链官能化，其产生在烷基中被卤素，氧或氮官能团取代的菲莫拉林 链，特别是福美罗瑞醇，羧酸酯和亚磺酸盐和磺酸酯，醚，醛，酮，酸，酰胺，硝基衍生物，疏水性，亲水和氟化烷基衍生物和聚合物。

公开(公告)号：US07052910B2

公开(公告)日：2006-05-30

申请号：US09984018

申请日：2001-10-26

Applicant: Naresh Kumar ,  Chinmoy Sankar Dey

Inventor： Naresh Kumar ,  Chinmoy Sankar Dey

IPC: C12N5/06 ,  C12N5/00 ,  C12N5/02

CPC classification number: C07K16/18 ,  C07K16/26 ,  C07K16/2869 ,  G01N33/5061 ,  G01N2800/042

Abstract: The present invention relates to the development of insulin resistant skeletal muscle cell culture model useful for the screening of compounds that enhance insulin receptor (IR) and insulin receptor substrate-1 (IRS-1) tyrosine phosphorylation required against type II diabetes.

公开(公告)号：US06989162B2

公开(公告)日：2006-01-24

申请号：US10403700

申请日：2003-03-31

Applicant: Ghulam Nabi Qazi ,  Om Parkash Suri ,  Kasturi Lal Bedi ,  Krishan Avtar Suri ,  Bishan Datt Gupta ,  Bupinder Singh Jaggi ,  Bal Krishan Kapahi ,  Naresh Kumar Satti ,  Musarat Amina ,  Bal Krishan Chandan ,  Neelam Sharma ,  Gurdarshan Singh

Inventor： Ghulam Nabi Qazi ,  Om Parkash Suri ,  Kasturi Lal Bedi ,  Krishan Avtar Suri ,  Bishan Datt Gupta ,  Bupinder Singh Jaggi ,  Bal Krishan Kapahi ,  Naresh Kumar Satti ,  Musarat Amina ,  Bal Krishan Chandan ,  Neelam Sharma ,  Gurdarshan Singh

IPC: A61K35/78 ,  A61K31/70 ,  A61K31/33 ,  A61K31/555 ,  A61K31/05

CPC classification number: A61K36/53 ,  Y10S514/893

Abstract: A process of isolation of pure Acteoside of high hepatoprotection from plant Colerbrookea oppositifolia, said process comprising steps of drying aerial parts of the plant, grounding the dried parts into powder, percolating the powder with water or ethanol for 3-4 times to obtain an extract, filtering the extract for clearing of suspended particles to obtain supernatant, drying the supernatant at about 45 to 55° C. to obtain a residue, fractionating the residue with chloroform, ethyl acetate, and butanol successively, subjecting butanol fraction to adsorption chromatography of SiO2 after adding methanol to the fraction, charging the adsorbed fraction to glass column, eluting the column with solvents of increasing polarity of methanol:chloroform to obtain further fractions and repeating the process one more time, subjecting the fractions to column chromatography to obtain fractions, concentrating the fractions under reduced pressure to obtain acteoside as residue; and a method of effectively hepatoprotecting a subject using pure Acteoside from plant Colerbrookea oppositifolia, said method comprising steps of administering appropriate low-dose of the acteoside to the subject.

Abstract translation: 从植物Colerbrookea oppositifolia中分离出高保护酶的纯Acteoside的过程，所述方法包括干燥植物的地上部分，将干燥部分粉碎成粉末，用水或乙醇渗滤粉末3-4次以获得提取物 过滤提取物以清除悬浮颗粒以获得上清液，在约45至55℃下干燥上清液，得到残余物，依次用氯仿，乙酸乙酯和丁醇分馏残余物，将丁醇级分进行吸附层析 在将甲醇加入到级分中后，将吸附的级分装入玻璃柱，用极性升高的甲醇：氯仿溶剂洗脱柱，得到更多的级分并重复该过程一次， 进行柱色谱分离，得到级分，减压浓缩，得到作为残留物的acteoside; 该方法包括以下步骤：向受试者施用合适的低剂量的acteoside。

公开(公告)号：US06937560B2

公开(公告)日：2005-08-30

申请号：US09802994

申请日：2001-05-22

Applicant: Daniel Albert Enns ,  Naresh Kumar Jain ,  Robert L. McCollum

Inventor： Daniel Albert Enns ,  Naresh Kumar Jain ,  Robert L. McCollum

IPC: H04L29/06 ,  H04L29/08 ,  H04L1/00

CPC classification number: H04L67/322 ,  H04L29/06 ,  H04L69/16 ,  H04L69/161 ,  H04L69/163 ,  H04L69/329

Abstract: A method and apparatus for selectively accelerating network communications provides improved operation of network communications through channels with long delays, such as a satellite communications channel. A configuration management mechanism provides a selection of acceleration configuration for particular addresses of devices that may communicate through the communications channels. Acceleration may be bypassed for particular addresses or classes of devices within the network and priorities may be assigned, permitting a cut-off of acceleration when a threshold number of sessions is reached. The method and system may also allow a higher priority class of session to preempt lower priority session by removing resources from the lower priority session and assigning them to the higher priority session. The data rate of the lower priority session is then lowered (due to the absence of acceleration or reduced buffer size) to reduce traffic flow.

Abstract translation: 用于选择性地加速网络通信的方法和装置通过诸如卫星通信信道的长延迟的信道提供网络通信的改进的操作。 配置管理机制为可以通过通信信道通信的设备的特定地址提供对加速配置的选择。 对于网络内的特定地址或设备类别可以绕过加速度，并且可以分配优先级，当达到阈值数量的会话时允许切断加速。 该方法和系统还可以允许较高优先级的会话通过从较低优先级会话中移除资源并将其分配给较高优先级的会话来抢占较低优先级的会话。 然后，较低优先级会话的数据速率降低（由于没有加速或减小缓冲区大小）以减少流量。

公开(公告)号：US06852759B2

公开(公告)日：2005-02-08

申请号：US10113220

申请日：2002-03-28

Applicant: Vishwa Nath Gupta ,  Vikram Bhardwaj ,  Bhupinder Singh ,  Bal Krishan Chandan ,  Krishan Avtar Suri ,  Naresh Kumar Satti ,  Om Parkash Suri ,  Sukhdev Swami Handa

Inventor： Vishwa Nath Gupta ,  Vikram Bhardwaj ,  Bhupinder Singh ,  Bal Krishan Chandan ,  Krishan Avtar Suri ,  Naresh Kumar Satti ,  Om Parkash Suri ,  Sukhdev Swami Handa

IPC: A61P1/10 ,  A61P1/16 ,  C07C51/38 ,  A01N37/00 ,  A61K31/20

CPC classification number: C07C51/38 ,  C07C57/03

Abstract: The present invention relates to a process for the preparation of trans-alkenoic acids of general formula CH3—(CH2)n—CH═(CH2)mCO2H where n=4 to 9 m=8 to 16. More particularly, the present invention relates to a process for the preparation of trans-tetracos-15-enoic acid, which is a bioactive constituent possessing dose-related hepatoprotective activity. The present invention also relates to the use thereof for hepatoprotection.

Abstract translation: 本发明涉及一种制备通式CH 3 - （CH 2）n -CH =（CH 2）m CO 2 H的反式链烯酸的方法，其中n = 4〜9μm= 8〜16。更具体地说，本发明涉及 涉及制备具有剂量相关性肝保护活性的生物活性成分的反式二十四碳烯酸的方法。 本发明还涉及其用于肝保护的用途。