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公开(公告)号：US20140309263A1
公开(公告)日：2014-10-16
申请号：US14169308
申请日：2014-01-31
Applicant: Meso Scale Technologies, LLC
Inventor： Simone Barbero , Eli N. Glezer , Anu Mathew , Mingyue Wang
IPC: G01N33/574 , A61K31/404 , A61K31/44
CPC classification number: G01N33/57438 , A61K31/404 , A61K31/44 , C12Q1/485 , G01N33/5743 , G01N2800/60
Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
Abstract translation: 本发明涉及诊断患者肾脏疾病的方法，以及监测肾脏疾病进展的方法和/或监测治疗剂或治疗方案的治疗方案的方法。 本发明还涉及结合本文所述的诊断方法使用的测定方法。
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公开(公告)号：US20140274775A1
公开(公告)日：2014-09-18
申请号：US14208040
申请日：2014-03-13
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Eli N. Glezer , John Kenten
IPC: G01N33/543
CPC classification number: G01N33/54306 , C12Q1/682 , C12Q1/6837 , C12Q1/6844 , C12Q1/6848 , C12Q2531/125 , C12Q2533/107 , C12Q2565/549
Abstract: The present invention is directed to methods for reducing cross-reactivity between species employed in multiplexed immunoassays.
Abstract translation: 本发明涉及降低多重免疫测定中使用的物种之间的交叉反应性的方法。
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公开(公告)号：US20140272939A1
公开(公告)日：2014-09-18
申请号：US14206284
申请日：2014-03-12
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Anahit Aghvanyan , Eli N. Glezer , John Kenten , George Sigal , Martin Stengelin
IPC: G01N33/53 , G01N33/569
CPC classification number: G01N33/54393 , C12Q1/6804 , G01N21/66 , G01N21/76 , G01N21/77 , G01N33/5306 , G01N33/5308 , G01N33/533 , G01N33/54306 , G01N33/56988 , G01N33/582 , G01N2021/7786 , C12Q2537/125 , C12Q2563/179
Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.
Abstract translation: 本发明涉及用于改善结合测定中测定特异性和性能的方法。
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公开(公告)号：US20140220007A1
公开(公告)日：2014-08-07
申请号：US14169289
申请日：2014-01-31
Applicant: MESO SCALE TECHNOLOGIES, LLC
Inventor： Eli N. Glezer , Mikayla Higgins , John Kenten , George Sigal
IPC: G01N33/564
CPC classification number: G01N33/564 , G01N2800/104 , G01N2800/52
Abstract: The present invention relates to methods of diagnosing lupus in a patient, as well as methods of monitoring the progression of lupus and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
Abstract translation: 本发明涉及诊断患者狼疮的方法，以及监测狼疮进展的方法和/或监测治疗剂或治疗方案治疗方案的方法。 本发明还涉及结合本文所述的诊断方法使用的测定方法。
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公开(公告)号：US20140151224A1
公开(公告)日：2014-06-05
申请号：US14170721
申请日：2014-02-03
Applicant: Meso Scale Technologies, LLC
Inventor： Eli N. Glezer , Jonathan K. Leland , Mark A. Billadeau , Joseph M. Leginus , Bandele Jeffrey-Coker , Jeff D. Debad , Koustubh A. Phalnikar , Sriram Jambunathan
IPC: G01N27/30
CPC classification number: G01N21/76 , B01J19/0046 , B01J2219/00653 , B01J2219/00725 , B01J2219/0074 , B01L3/5027 , B01L3/502715 , B01L3/5029 , B01L9/527 , B01L2200/0684 , B01L2200/10 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0867 , B01L2300/0887 , B01L2400/049 , B01L2400/0688 , B33Y80/00 , C12Q1/001 , C40B40/10 , G01N27/30 , G01N33/5438 , G01N2458/30 , Y10T436/25 , Y10T436/25375 , Y10T436/255
Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.
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Patent Agency Ranking
公开(公告)号：US20250020662A1
公开(公告)日：2025-01-16
申请号：US18617868
申请日：2024-03-27
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , John Kenten , Galina Nikolenko
IPC: G01N33/68
Abstract: The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US12196749B2
公开(公告)日：2025-01-14
申请号：US16942130
申请日：2020-07-29
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Jonathan K. Leland , Mark A. Billadeau , Joseph M. Leginus , Bandele Jeffrey-Coker , Jeff D. Debad , Koustubh A. Phalnikar , Sriram Jambunathan
IPC: G01N33/543 , B01J19/00 , B01L3/00 , B01L9/00 , C12Q1/00 , G01N21/76 , G01N27/30 , B33Y80/00 , C40B40/10
Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.
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公开(公告)号：US12130297B2
公开(公告)日：2024-10-29
申请号：US16938284
申请日：2020-07-24
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Carl Edens , Bandele Jeffrey-Coker , Sandor Kovacs , Christopher Frye
IPC: G01N35/00 , B01F11/00 , B01F31/22 , B06B1/16 , G01N33/543 , G01N35/10 , B01F101/23
CPC classification number: G01N35/00029 , B01F31/22 , B06B1/16 , B06B1/167 , G01N33/54366 , G01N35/00732 , G01N35/0099 , G01N35/10 , B01F2101/23 , G01N2035/00148
Abstract: The present invention relates to a system for performing assays on a solid phase to measure the level of analyte in a sample. Such a system may perform immunoassays using electrochemiluminescence (ECL) including a counterbalanced orbital shaking apparatus for assay consumables.
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公开(公告)号：US11982871B2
公开(公告)日：2024-05-14
申请号：US17492187
申请日：2021-10-01
Applicant: Meso Scale Technologies, LLC.
Inventor： Ian Chamberlin , Charles M. Clinton , Eli N. Glezer , Bandele Jeffrey-Coker , Manish Kochar , Sandor Kovacs , D. T. Le , Aaron Leimkuehler , George Sigal , Leo Tabakin , Jon Willoughby
CPC classification number: G02B7/36 , G01N21/253 , G01N21/6452 , G01N35/028
Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.
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公开(公告)号：US11971418B2
公开(公告)日：2024-04-30
申请号：US17169805
申请日：2021-02-08
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , John Kenten , Galina Nikolenko
IPC: G01N33/68
CPC classification number: G01N33/6893 , G01N2800/347 , G01N2800/52
Abstract: The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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