摘要:
The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting and MMP-3 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 and MMP-3 inhibitors.
摘要:
The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 inhibitors.
摘要:
A transistor is provided which advantageously utilizes a part of the area which, in conventional transistors, is provided for the isolation between the transistors. In this case, the channel width can be enlarged in a self-aligned manner without the risk of short circuits. The field-effect transistor according to the invention has the advantage that it is possible to ensure a significant increase in the effective channel width for the forward current ION compared with previously used, conventional transistor structures, without having to accept a reduction of the integration density that can be attained. Thus, by way of example, the forward current ION can be increased by up to 50%, without having to alter the arrangement of the active regions or of the trench isolation.
摘要翻译:提供了一种晶体管,其有利地利用了在常规晶体管中提供用于晶体管之间的隔离的区域的一部分。 在这种情况下,可以以自对准的方式扩大通道宽度,而不会出现短路的风险。 根据本发明的场效应晶体管的优点在于,与先前使用的传统晶体管结构相比,可以确保正向电流ION的有效沟道宽度的显着增加,而不必接受集成密度的降低 可以实现。 因此,作为示例,正向电流I ON ON可以增加高达50%,而不必改变有源区域或沟槽隔离的布置。
摘要:
The invention relates to a method for making oligomeric isocyanates by reacting diisocyanates in the presence of a catalyst, wherein the catalyst comprises a saline compound prepared from a five-membered N-heterocycles and the N-heterocycle comprises at least one N—H function in the five-membered ring, to the products produced in this way and to polymers prepared from these products.
摘要:
In a method for examining structures on a wafer, at least one mask, which is applied on the wafer and is fabricated by exposure processes, is used for fabricating the structures. Test circuits with test structures are placed on the mask in predetermined reference positions. In order to check the structures and/or the exposure processes, electrical parameters of the test circuits are detected and evaluated in a location-dependent manner.
摘要:
With increasing integration density of integrated circuits, the packing density in test regions (kerf structures) located between the integrated circuits cannot be increased substantially, since the majority of the available area is occupied by contact areas. The invention is therefore directed toward a test structure region on a wafer having contact areas for applying voltages and test components between the contact areas. The test structure includes at least two test components that are arranged between two adjacent contact areas. The test components are each connected to the adjacent contact areas so that a voltage can be applied to the test components via the contact areas.
摘要:
The invention relates to the use of 4-isocyanatomethyloctane 1,8-diisocyanate isocyanatononane, (TIN) and TIN-containing mixtures for preparing polyurethane lacquers and coatings which can be applied from an aqueous medium.
摘要:
The present invention relates to a polyisocyanate mixture containing isocyanate trimers provided thati) 30 to 100 mole percent of the trimers are iminooxadiazine diones B and ##STR1## ii) 0 to 70 mole percent of the trimers are isocyanurates A iii) less than 10 mole percent of the polyisocyanate mixture is of the uretone imine structural type, andiv) the ratio of the sum of the mole percents of trimers A and B to the mole percent of uretdiones is greater than 4:1whereinR.sup.1, R.sup.2 and R.sup.3 are the same or different and represent the groups obtained by removing an isocyanate group from an aliphatic, cycloaliphatic, aromatic and/or araliphatic isocyanate having an NCO content of less than 70% and/or their oligomers.The present invention also relates to a process for the preparation of these isocyanate trimers, mixtures of these isocyanate trimers with other polyisocyanates and compositions containing these isocyanate trimers, in which the isocyanate groups may optionally be blocked with blocking agents, and compounds containing two or more isocyanate-reactive groups.
摘要:
Apparatus for allowing measurements to be made of a blood sample comprises a shaft and at least first and second blood collection members. The blood collection members are independently rotatable about the shaft. Each blood collection member includes: a blood analysis part for receiving a blood sample, plural conductive contacts, and plural conductors extending between the blood analysis part and respective ones of the conductive contacts. The apparatus also includes plural terminals configured to provide an electrical connection with the plural conductive contacts on a first member when the apparatus is in a first configuration and to provide an electrical connection with the plural conductive contacts on a second member when the apparatus is in a second configuration, thereby allowing successive measurements of at least one parameter of blood samples provided on the blood analysis parts of the first and second members.
摘要:
A connecting device of a vehicle drive-train, located outside a variable-speed transmission, for rotationally coupling a shaft to a drive-train element. A sliding sleeve is rotationally fixed on the shaft but slides axially between first and second positions. In the first position, the shaft is rotationally disengaged from the drive-train element and, in the second position, they are rotationally coupled. An actuator displaces the sliding sleeve between the first and second positions, with a shift groove along a peripheral contour of the sliding sleeve and engagement members for engaging in the groove. The sliding sleeve can rotate and move axially relative to the engagement members and the groove is shaped as a curved guiding such that, when the engagement members engage in the groove and the sliding sleeve rotates relative to the engagement member, the sliding sleeve moves axially between the first and second positions by virtue of the groove.