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118 条记录 (耗时 0.073 秒)

    EG-VEGF NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USE
    105.
    发明申请
    EG-VEGF NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USE 有权
    EG-VEGF核酸和多肽及其使用方法

    公开(公告)号：US20070213268A1

    公开(公告)日：2007-09-13

    申请号：US11537472

    申请日：2006-09-29

    申请人： Napoleone Ferrara ,  Colin Watanabe ,  William Wood ,  Theresa Shek

    发明人： Napoleone Ferrara ,  Colin Watanabe ,  William Wood ,  Theresa Shek

    IPC分类号： A61K38/18 ,  A61K31/7088 ,  C12P21/08 ,  C12Q1/66 ,  C12Q1/68 ,  G01N33/563

    CPC分类号： A61K39/3955 ,  A61K38/00 ,  A61K38/1808 ,  C07K14/52 ,  C07K16/22 ,  C07K2317/76 ,  G01N33/74 ,  G01N2500/00

    摘要： The present invention is directed to novel polypeptides designated herein as EG-VEGF and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Also provided herein are methods of screening for modulators of EG-VEGF. Furthermore, methods and related methods of treatment are described herein which pertain to regulating cellular proliferation and chemotaxis.

    摘要翻译： 本发明涉及本文称为EG-VEGF的新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本文还提供了筛选EG-VEGF调节剂的方法。 此外，本文描述了涉及调节细胞增殖和趋化性的方法和相关的治疗方法。

    EG-VEGF NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USE
    108.
    发明申请
    EG-VEGF NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USE 审中-公开
    EG-VEGF核酸和多肽及其使用方法

    公开(公告)号：US20130189273A1

    公开(公告)日：2013-07-25

    申请号：US13102517

    申请日：2011-05-06

    申请人： Napoleone Ferrara ,  Colin Watanabe ,  William I. Wood ,  Theresa Shek

    发明人： Napoleone Ferrara ,  Colin Watanabe ,  William I. Wood ,  Theresa Shek

    IPC分类号： A61K39/395 ,  C07K16/22 ,  A61K38/18

    CPC分类号： A61K39/3955 ,  A61K38/00 ,  A61K38/1808 ,  C07K14/52 ,  C07K16/22 ,  C07K2317/76 ,  G01N33/74 ,  G01N2500/00

    摘要： The present invention is directed to novel polypeptides designated herein as EG-VEGF and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Also provided herein are methods of screening for modulators of EG-VEGF. Furthermore, methods and related methods of treatment are described herein which pertain to regulating cellular proliferation and chemotaxis.

    摘要翻译： 本发明涉及本文称为EG-VEGF的新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本文还提供了筛选EG-VEGF调节剂的方法。 此外，本文描述了涉及调节细胞增殖和趋化性的方法和相关的治疗方法。

    EG-VEGF nucleic acids and polypeptides and method of use
    109.
    发明授权
    EG-VEGF nucleic acids and polypeptides and method of use 有权
    EG-VEGF核酸和多肽及其使用方法

    公开(公告)号：US07264801B2

    公开(公告)日：2007-09-04

    申请号：US10027603

    申请日：2001-12-19

    申请人： Napoleone Ferrara ,  Colin Watanabe ,  William I. Wood ,  Theresa Shek

    发明人： Napoleone Ferrara ,  Colin Watanabe ,  William I. Wood ,  Theresa Shek

    IPC分类号： A61K39/395 ,  C07K16/00 ,  C07K16/22 ,  G01N33/53

    CPC分类号： A61K39/3955 ,  A61K38/00 ,  A61K38/1808 ,  C07K14/52 ,  C07K16/22 ,  C07K2317/76 ,  G01N33/74 ,  G01N2500/00

    摘要： The present invention is directed to novel polypeptides designated herein as EG-VEGF and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Also provided herein are methods of screening for modulators of EG-VEGF. Furthermore, methods and related methods of treatment are described herein which pertain to regulating cellular proliferation and chemotaxis.

    摘要翻译： 本发明涉及本文称为EG-VEGF的新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本文还提供了筛选EG-VEGF调节剂的方法。 此外，本文描述了涉及调节细胞增殖和趋化性的方法和相关的治疗方法。