公开(公告)号：US11913924B2

公开(公告)日：2024-02-27

申请号：US18128584

申请日：2023-03-30

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Zheng Ouyang

IPC: G01N30/95 ,  H01J49/16 ,  H01J49/00 ,  H01J49/04 ,  G01N30/91 ,  G01N33/49

CPC classification number: G01N30/95 ,  G01N30/91 ,  G01N33/49 ,  H01J49/0031 ,  H01J49/0404 ,  H01J49/0409 ,  H01J49/0431 ,  H01J49/167 ,  H01J49/168

Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.

公开(公告)号：US20230341360A1

公开(公告)日：2023-10-26

申请号：US18128584

申请日：2023-03-30

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Zheng Ouyang

IPC: G01N30/95 ,  H01J49/16 ,  H01J49/00 ,  H01J49/04 ,  G01N30/91 ,  G01N33/49

CPC classification number: G01N30/95 ,  H01J49/168 ,  H01J49/0031 ,  H01J49/0409 ,  H01J49/0431 ,  H01J49/0404 ,  H01J49/167 ,  G01N30/91 ,  G01N33/49

Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.

公开(公告)号：US11680876B2

公开(公告)日：2023-06-20

申请号：US17346576

申请日：2021-06-14

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  Wenpeng Zhang

IPC: G01N1/40 ,  B01D11/00 ,  B01D11/02 ,  B01D15/10 ,  H01J49/00 ,  H01J49/04

CPC classification number: G01N1/405 ,  B01D11/00 ,  B01D11/02 ,  B01D15/10 ,  H01J49/0031 ,  H01J49/0436 ,  G01N2001/4061 ,  Y10T436/255

Abstract: Systems and methods for analyzing an analyte extracted from a sample using an adsorbent material.

公开(公告)号：US20220221442A1

公开(公告)日：2022-07-14

申请号：US17584100

申请日：2022-01-25

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  He Wang ,  Nicholas E. Manicke ,  Robert Graham Cooks ,  Qian Yang ,  Jiangjiang Liu

IPC: G01N33/49 ,  G01N1/28 ,  H01J49/16 ,  H01J49/00 ,  G01N33/487

Abstract: The invention generally relates to a sample dispenser including an internal standard and methods of use thereof.

公开(公告)号：US11287414B2

公开(公告)日：2022-03-29

申请号：US16936683

申请日：2020-07-23

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  He Wang ,  Nicholas E. Manicke ,  Robert Graham Cooks ,  Qian Yang ,  Jiangjiang Liu

IPC: G01N33/49 ,  G01N1/28 ,  H01J49/16 ,  H01J49/00 ,  G01N33/487 ,  G01N1/10

Abstract: The invention generally relates to a sample dispenser including an internal standard and methods of use thereof.

公开(公告)号：US20220028674A1

公开(公告)日：2022-01-27

申请号：US17395909

申请日：2021-08-06

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Zheng Ouyang

IPC: H01J49/00 ,  H01J49/16 ,  G01N30/91 ,  G01N30/95 ,  H01J49/04

Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.

公开(公告)号：US11119081B2

公开(公告)日：2021-09-14

申请号：US16905193

申请日：2020-06-18

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Zheng Ouyang

IPC: G01N30/95 ,  H01J49/16 ,  H01J49/00 ,  H01J49/04 ,  G01N30/91 ,  G01N33/49

Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.

公开(公告)号：US10930481B2

公开(公告)日：2021-02-23

申请号：US14909269

申请日：2014-08-06

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  Linfan Li ,  Xiaoyu Zhou

IPC: H01J49/00 ,  H01J49/04

Abstract: The invention generally relates to sample analysis with a miniature mass spectrometer. In certain embodiments, the invention provides methods that involve generating ions of a first analyte and ions of a second analyte. Those ions are transferred through a discontinuous sample introduction interface into a first ion trap of a mass spectrometer in a manner in which the discontinuous sample introduction interface remains open during the transferring. The discontinuous sample introduction interface is closed and the ions are sequentially transferred to a second ion trap of the mass spectrometer where they are sequentially analyzed.

公开(公告)号：US10761083B2

公开(公告)日：2020-09-01

申请号：US15357048

申请日：2016-11-21

Applicant: Purdue Research Foundation

Inventor： Zheng Ouyang ,  He Wang ,  Nicholas E. Manicke ,  Robert Graham Cooks ,  Qian Yang ,  Jiangjiang Liu

IPC: G01N33/00 ,  G01N33/49 ,  G01N1/28 ,  H01J49/16 ,  H01J49/00 ,  G01N33/487 ,  G01N1/10

Abstract: The invention generally relates to a sample dispenser including an internal standard and methods of use thereof.

公开(公告)号：US10732159B2

公开(公告)日：2020-08-04

申请号：US16107296

申请日：2018-08-21

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Zheng Ouyang

IPC: H01J49/00 ,  G01N30/95 ,  H01J49/16 ,  H01J49/04 ,  G01N30/91 ,  G01N33/49

Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.