公开(公告)号：US5258620A

公开(公告)日：1993-11-02

申请号：US773921

申请日：1991-10-30

Applicant: Ryoichi Sueyasu ,  Mayumi Watanabe ,  Kazuhiko Sagara ,  Hidehiko Kaya

Inventor： Ryoichi Sueyasu ,  Mayumi Watanabe ,  Kazuhiko Sagara ,  Hidehiko Kaya

IPC: G01N21/35 ,  G01N21/359 ,  G01N33/04

CPC classification number: G01N21/359 ,  G01N21/3577 ,  G01N33/04 ,  G01N2201/129 ,  Y10S250/91

Abstract: A sample having a specific optical path length of 1 to 15 mm is irradiated with near infrared of two or more wavelengths selected from 700 to 1200 nm to determine constituents of dairy products. Preferably, a pair of specific wavelengths comprise a first wavelength having a high correlation with a target constituent and a second wavelength having a low correlation with the target constituent or comprise wavelengths both having high correlations with the target constitutent. Quantities of near infrared of these two specific wavelengths transmitted by the sample are measured to determine absorbencies and a multiple linear regression equation is used to calculate the constituent on the basis of the absorbencies.

Abstract translation: 照射具有1〜15mm的特定光程长度的样品，从700〜1200nm的两个以上的波长的近红外线照射，测定乳制品的成分。 优选地，一对特定波长包括与目标成分具有高相关性的第一波长和与目标成分具有低相关性的第二波长或包括与目标成分具有高相关性的波长。 测量由样品传输的这两种特定波长的近红外光量以确定吸光度，并且使用多元线性回归方程式根据吸光度计算成分。

公开(公告)号：US5237515A

公开(公告)日：1993-08-17

申请号：US683146

申请日：1991-04-10

Applicant: James N. Herron ,  Ai-Ping Wei

Inventor： James N. Herron ,  Ai-Ping Wei

IPC: G01N21/64

CPC classification number: G01N21/6428 ,  G01N2021/6421 ,  G01N2201/129

Abstract: The energy transfer efficiency of a donor-acceptor pair of fluorescent dyes can be determined by first measuring the fluorescence and absorption spectra of donor-protein, acceptor-protein, mixture of donor-protein and acceptor-protein, and donor-acceptor-protein conjugates, then separating the respective spectra into their respective donor-protein complex and acceptor-protein complex components using multiple linear regression, and then determining the transfer efficiency on the basis of the quenching of the donor fluorescence based on the spectral data thus obtained.

Abstract translation: 供体 - 受体对荧光染料的能量转移效率可以通过首先测量供体 - 蛋白质，受体 - 蛋白质，供体 - 蛋白质和受体 - 蛋白质的混合物和供体 - 受体 - 蛋白质缀合物的荧光和吸收光谱来确定 ，然后使用多元线性回归将相应的光谱分离成它们各自的供体 - 蛋白质复合物和受体 - 蛋白质复合物组分，然后基于由此获得的光谱数据基于供体荧光的猝灭确定转移效率。

公开(公告)号：US5227986A

公开(公告)日：1993-07-13

申请号：US639436

申请日：1991-01-10

Applicant: Hiroshi Yokota ,  Masaaki Kimura

Inventor： Hiroshi Yokota ,  Masaaki Kimura

IPC: G01N21/27 ,  G01J3/28 ,  G01N21/31

CPC classification number: G01N21/31 ,  G01J3/28 ,  G01N2201/129

Abstract: A spectrometric method for determining a physical or a chemical target quantity by performing the photometric measurement at plural wavelengths predetermined which includes the steps of measuring variation vectors by varying error variation factors by predetermined units which are defined in a space having a dimension equal to the number of the plural wavelengths, seeking for a subspace of the space which is orthogonal to all variation vectors, performing the photometric measurement for samples having known values of the target quantity, projecting vectors obtained from the photometric measurement for samples on the subspace and calculating a calibration curve using data obtained by the projection on the subspace.

公开(公告)号：US5146413A

公开(公告)日：1992-09-08

申请号：US42864

申请日：1987-04-24

Applicant: Gary W. Shires

Inventor： Gary W. Shires

IPC: G01F17/00 ,  G01F25/00 ,  G01N21/27 ,  G01N35/00 ,  G01N35/10

CPC classification number: G01N35/10 ,  G01F17/00 ,  G01F25/0092 ,  G01N21/274 ,  G01N2035/00673 ,  G01N2201/129

Abstract: A method for chemistry systems analysis to identify the performance of the functional components of the system, specifically, those of volumes dispensed and optical linearity. Employing a linear regression comparison between predetermined absorbance values, calculated from Beer's Law, and absorbance values obtained from the optical system under test, a value correction constant derived from the regression comparison may be applied to all subsequent absorbance values. Absorbance values, obtained from the optical system as a result of analyzing dilutions are by the pipetting system of material having a greater concentration but the same molar absorbtivity constant as the material used for the linearity evaluation, can be corrected to a value that does not reflect any optical system bias, and may be considered as the divident for the function of converting absorbance values into volumes dispensed. The divisor of the convertion function will be derived from the predetermined absorbance of the concentrate, using Beer's Law, and dividing that by the total volume requested by the volumes evaluation, leaving an absorbance value that equals a lul delivery. The volume dispensed by the pipetting system may then be calculated by dividing the corrected absorbance value by the lul absorbance value, yielding a quotient identifying the actual volume delivered.

Abstract translation: 一种用于化学系统分析的方法，用于识别系统的功能组件的性能，特别是分配的体积和光学线性的性能。 采用从啤酒定律计算的预定吸光度值与从测试光学系统获得的吸光度值之间的线性回归比较，可以将所有随后的吸光度值应用于从回归比较得到的值校正常数。 作为分析稀释度的结果，从光学系统获得的吸光度值是通过具有较高浓度但与用于线性评估的材料相同的摩尔吸光度常数的材料的吸移系统可以校正为不反映的值 任何光学系统偏差，并且可以被认为是将吸光度值转换成分配的体积的函数的分数。 转换函数的除数将使用Beer定律从浓缩物的预定吸光度导出，并将其除以体积评估所要求的总体积，留下等于输送的吸光度值。 然后可以通过将校正的吸光度值除以lul吸光度值来计算由移液系统分配的体积，从而产生识别递送的实际体积的商。

公开(公告)号：US5014225A

公开(公告)日：1991-05-07

申请号：US390905

申请日：1989-08-08

Applicant: William Vidaver ,  Peter Toivonen ,  Sylvain Dube

Inventor： William Vidaver ,  Peter Toivonen ,  Sylvain Dube

IPC: G01N21/63 ,  G01N21/64

CPC classification number: G01N21/645 ,  G01N21/64 ,  G01N2021/635 ,  G01N2021/6423 ,  G01N2021/8466 ,  G01N2201/129

Abstract: An apparatus and method for determining the photosynthetic activity of a plant by determining the chlorophyll fluorescence of the plant is provided. The apparatus includes a light impermeable housing, a light to illuminate the housing, a light intensity in the housing and to adjust the light intensity controller. The light intensity may be between zero and 700 micromoles of photons per square meter per second. The monitor may be a photodiode protected by light filters which permit only light of wavelengths corresponding to plant fluorescence emission to pass to the photodiode. A computer analysis of the data obtained, corrects for Dark and Straylight signals in the housing and normalizes the data by correcting for the Fo fluorescence. A method of estimating Fo is provided which includes illuminating a light impermeable chamber housing a plant with light of a pre-determined intensity, measuring the fluorescence emission, determining the slope of a first regression line prior to full opening of the shutter; determining the slope of a second regression line of measurements after the shutter is fully opened and determining the intersecting point between these two lines. A method of determining the corrected and normalized fluorescence emissions from a plant is provided.

Abstract translation: 提供了通过确定植物的叶绿素荧光来确定植物的光合活性的装置和方法。 该装置包括不透光的外壳，照亮外壳的光，外壳中的光强度并调节光强度控制器。 光强度可以在每平方米每秒零到700微摩尔的光子之间。 监视器可以是由仅允许对应于植物荧光发射的波长的光通过光电二极管的光过滤器保护的光电二极管。 对获得的数据进行计算机分析，校正外壳中的Dark和Straylight信号，并通过校正Fo荧光来对数据进行归一化。 提供一种估计Fo的方法，其包括用预定强度的光照射容纳植物的不透光室，测量荧光发射，确定在快门完全打开之前的第一回归线的斜率; 在快门完全打开之后确定第二回归测量线的斜率，并确定这两条线之间的相交点。 提供了确定来自植物的校正和归一化的荧光发射的方法。

公开(公告)号：US12111252B2

公开(公告)日：2024-10-08

申请号：US18569746

申请日：2022-06-17

Applicant: REPSOL, S.A.

Inventor： Miguel Rubio Moreno ,  Francisco Javier Carvajal González ,  Sonia Segura Fernández ,  Enrique Domínguez Ramos

IPC: G01N21/3563 ,  B07C5/342 ,  B29B17/02 ,  B29K75/00 ,  B29K105/04 ,  B29K105/06

CPC classification number: G01N21/3563 ,  B07C5/342 ,  B29B17/02 ,  B29B2017/0203 ,  B29B2017/0279 ,  B29K2075/00 ,  B29K2105/04 ,  B29K2105/065 ,  G01N2201/127 ,  G01N2201/129

Abstract: A method for sorting flexible polyurethane foams including: a) providing two or more calibration samples of conventional flexible polyurethane foams, two or more calibration samples of high resilience (HR) flexible polyurethane foams, and two or more calibration samples of viscoelastic flexible polyurethane foams, and obtaining a mid-infrared (MIR) spectrum of each calibration sample; b) carrying out a spectral pre-processing of the spectra of all the calibration samples and, then a first PCA to define a first library; c) carrying out a spectral pre-processing of the infrared spectra of conventional and HR calibration samples and, then a second PCA to define a second library; d) obtaining the MIR spectrum of a sample of polyurethane foam and, based on the first and second libraries, classifying the sample of polyurethane foam as a conventional, HR or viscoelastic polyurethane foam, or as a foam that is neither a conventional, a HR or a viscoelastic polyurethane foam.

公开(公告)号：US12092521B2

公开(公告)日：2024-09-17

申请号：US17685595

申请日：2022-03-03

Applicant: Finesse Solutions, Inc.

Inventor： Mark Selker ,  Barbara Paldus

IPC: G01J3/44 ,  G01J3/02 ,  G01N21/65 ,  G02B6/02

CPC classification number: G01J3/44 ,  G01J3/0218 ,  G01N21/65 ,  G02B6/02385 ,  G01N2201/08 ,  G01N2201/129 ,  G02B6/02328

Abstract: A method of determining the identity and concentration of a target analyte present in a biological sample includes: introducing a first target analyte into a hollow core of an optical fiber; introducing a first reference calibrant into the hollow core of the optical fiber; transmitting light from a laser light source through the hollow core of the optical fiber and the first target analyte to generate a first Raman anti-Stokes analyte emission corresponding to the first target analyte; receiving the first Raman anti-Stokes analyte emission at a spectral analysis system optically coupled to the optical fiber; and deriving Raman anti-Stokes spectral peaks or spectra of the first target analyte at the spectral analysis system based on the first Raman anti-Stokes analyte emission.

公开(公告)号：US20240287893A1

公开(公告)日：2024-08-29

申请号：US18176227

申请日：2023-02-28

Applicant: SAUDI ARABIAN OIL COMPANY

Inventor： Qasim Sahu ,  Adrian Cesar Cavazos Sepulveda

IPC: E21B47/107 ,  E21B43/26 ,  G01N33/28

CPC classification number: E21B47/107 ,  E21B43/26 ,  E21B43/2607 ,  G01N21/3577 ,  G01N33/2823 ,  E21B2200/20 ,  G01N2201/129

Abstract: A monitoring system includes a spectroscopic probe in fluid connection with a fracturing fluid, reference spectra obtained from one or more fracturing fluid components, and a computer in communication with the spectroscopic probe. The computer includes a predictive model generated from the reference spectra. The computer also includes instructions to compare spectroscopic data obtained from the spectroscopic probe with the predictive model. A modified well fracturing system includes a monitoring system located at a surface location of a hydrocarbon-bearing reservoir and a surface pump in fluid connection with the fracturing fluid source and a wellbore of the hydrocarbon-bearing reservoir. A method for monitoring a fracturing fluid is also described.

公开(公告)号：US12073924B2

公开(公告)日：2024-08-27

申请号：US17643128

申请日：2021-12-07

Applicant: Genzyme Corporation

Inventor： Dhanuka Pulasthi Wasalathanthri ,  Jagdish C. Tewari ,  Xuezhen Kang ,  Marina Hincapie ,  Shawn L. Barrett ,  Julie Susanne Pollock

IPC: C12M3/00 ,  B01L3/00 ,  C07K1/16 ,  C12M1/00 ,  C12M1/12 ,  C12M1/36 ,  G01N21/3577 ,  G01N21/552 ,  G01N30/46 ,  G01N30/78 ,  G01N30/86 ,  G16C20/10 ,  B01D15/18 ,  G01N21/35 ,  G01N21/84 ,  G01N30/88

CPC classification number: G16C20/10 ,  C07K1/16 ,  C12M21/14 ,  C12M37/00 ,  C12M41/48 ,  C12M47/12 ,  G01N21/3577 ,  G01N21/552 ,  G01N30/46 ,  G01N30/78 ,  G01N30/86 ,  B01D15/1814 ,  B01D15/1871 ,  G01N2021/3595 ,  G01N2021/8416 ,  G01N2030/8813 ,  G01N2030/8886 ,  G01N2201/129

Abstract: The disclosure features methods that include obtaining a vibrational spectrum of a solution in a biological manufacturing system, analyzing the vibrational spectrum using a first chemometrics model to determine a value of a first quality attribute associated with the solution, analyzing the vibrational spectrum using a second chemometrics model to determine a value of a second quality attribute associated with the solution, and adjusting at least one parameter of a purification unit of the biological manufacturing system based on at least one of the values of the first and second quality attributes.

公开(公告)号：US20240241058A1

公开(公告)日：2024-07-18

申请号：US18560104

申请日：2022-03-10

Applicant: JFE STEEL CORPORATION

Inventor： Masao INOSE ,  Seiya SUGAWARA

IPC: G01N21/71 ,  C21C5/46

CPC classification number: G01N21/718 ,  C21C5/4673 ,  G01N2201/0697 ,  G01N2201/129

Abstract: Provided is a slag component analysis method capable of quickly and accurately measuring slag components generated during refining of molten iron. The method comprises: irradiating a surface of slag to be analyzed with a pulse laser a plurality of times to turn part of the slag into plasma; dispersing excitation light obtained from the slag turned into plasma and acquiring an emission spectrum of an element contained in the slag per one pulse laser irradiation or per a plurality of pulse laser irradiations; and deriving a target component concentration or component amount ratio from the acquired emission spectrum, wherein the slag to be analyzed is slag generated in a converter-type refining furnace, and in the process of turning part of the slag into plasma, the pulse laser is applied from a side of the converter-type refining furnace tilted to remove the slag generated in the converter-type refining furnace.