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公开(公告)号：US11432531B2
公开(公告)日：2022-09-06
申请号：US16826709
申请日：2020-03-23
Inventor： Jesus Rene Villalobos , Octavio Sanchez , Cesar Meneses
Abstract: In accordance with embodiments disclosed herein, there are provided methods and systems for real-time beef cattle monitoring utilizing Radio-Frequency Identification (RFID) based technologies. For example, there is disclosed a system having at least a memory to store instructions; a processor to execute the instructions; a database to store data for heads of livestock, wherein each head of livestock is individually identified via a Radio-Frequency Identification (RFID) tag, the RFID tag uniquely identifying each of the heads of livestock to the system; a plurality of antennas to read information transmitted from the RFID tags; a transactional and analytical server to receive the information transmitted from the RFID tags and to store the information in the database; wherein the transactional and analytical server to further analyze the information stored in the database to identify when each head of livestock is present within a defined feeding zone; and monitoring the heads of livestock for anomalous feeding behavior based on the analysis. Other related embodiments are disclosed.
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公开(公告)号：US20220273365A1
公开(公告)日：2022-09-01
申请号：US17637484
申请日：2020-08-27
Applicant: Arizona Board of Regents on behalf of Arizona State University , MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Inventor： Kaushal Rege , Inam Ridha , Russell Urie , Pelagia Kouloumberis , Shelley Noland
Abstract: The present invention provides a method of nerve repair using localized delivery of heat. The method involves localized induction of hyperthermia for end-to-end attachment of severed peripheral nerves by delivering stimulus responsive materials and exposing them to an excitation source under conditions wherein they emit heat. The generation of heat effects the joining of the nerve ends.
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公开(公告)号：US11419524B2
公开(公告)日：2022-08-23
申请号：US15309641
申请日：2015-05-08
Inventor： Marco Santello
Abstract: The invention relates to human limb and joint movement pattern detection and analysis and is directed to warning systems for repetitive motion injuries and methods for warning a subject of movements at increased risk for repetitive use injuries, for example, using the warning systems. The invention tracks limb and joint movement of a subject during repetitive motion activities and can signal the subject to perform ergonomically safe movements.
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公开(公告)号：US11413616B2
公开(公告)日：2022-08-16
申请号：US16413416
申请日：2019-05-15
Inventor： Cody Youngbull , Andrew Hatch , Andrew Larsen , Tathagata Ray , Matthew Underhill
IPC: B01L3/00 , B01L7/00 , C12Q1/6848 , C12Q1/686 , B01F33/302 , B01F33/3033
Abstract: Described herein are systems relating to a continuous-flow instrument that includes all necessary components for digital droplet quantification without the need to introduce key reagents or collect and transfer droplets between stages of instrument operation. Digital quantification can proceed without any additional fluid or consumable handling and without exposing fluids to risk of external contamination.
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公开(公告)号：US20220204401A1
公开(公告)日：2022-06-30
申请号：US17565025
申请日：2021-12-29
Applicant: The Regents of the University of California , Arizona Board of Regents on Behalf of Arizona State University
Inventor： Gaurav Sant , Laurent G. Pilon , Bu Wang , Narayanan Neithalath , Zhenhua Wei , Benjamin Young , Gabriel D. Falzone , Dante Simonetti
Abstract: A manufacturing process of a concrete product includes: (1) extracting calcium from solids as portlandite; (2) forming a cementitious slurry including the portlandite; (3) shaping the cementitious slurry into a structural component; and (4) exposing the structural component to carbon dioxide sourced from a flue gas stream, thereby forming the concrete product.
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Patent Agency Ranking
126.发明申请公开(公告)号：US20220193681A1
公开(公告)日：2022-06-23
申请号：US17389253
申请日：2021-07-29
Inventor： Cody YOUNGBULL , Andrew HATCH , Tathagata RAY , Andrew LARSEN , Matthew UNDERHILL
Abstract: Systems and methods for continuous flow polymerase chain reaction (PCR) are provided. The system comprises an injector, a mixer, a coalescer, a droplet generator, a detector, a digital PCR system, and a controller. The injector takes in a sample, partitions the sample into sample aliquots with the help of an immiscible oil phase, dispenses waste, and sends the sample aliquot to the mixer. The mixer mixes the sample aliquot with a PCR master mix and diluting water, dispenses waste, and sends the sample mixture (separated by an immiscible oil) to the coalescer. The coalescer coalesces the sample mixture with primers dispensed from a cassette, dispenses waste, and sends the reaction mixture (separated by an immiscible oil) to the droplet generator. The droplet generator converts the sample mixture into an emulsion where aqueous droplets of the reaction mixture are maintained inside of an immiscible oil phase and dispenses droplets to the digital PCR system. The digital PCR system amplifies target DNAs in the droplets. The detector detects target DNAs in the droplets. The controller controls the system to run automatically and continuously.
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127.发明授权公开(公告)号：US11364502B2
公开(公告)日：2022-06-21
申请号：US15774558
申请日：2016-11-14
Inventor： Deirdre Meldrum , Laimonas Kelbauskas , Wacey Teller , Meryl Rodrigues , Hong Wang , Ganquan Song , Yanqing Tian , Fengyu Su , Xiangxing Kong , Liqiang Zhang
Abstract: A microfluidic device includes a first substrate including at least one microfluidic channel and a plurality of microwells, as well as a cooperating second substrate defining multiple split-walled cell trap structures that are registered with and disposed within the plurality of microwells. A method for performing an assay includes flowing cells and a first aqueous medium into a plurality of microwells of a microfluidic device, wherein each microwell includes a cell trap structure configured to trap at least one cell. The method further comprises flowing a nonpolar fluid with low permeability for analytes of interest through a microfluidic channel to flush a portion of the first aqueous medium from the microfluidic channel while retaining another portion of the first aqueous medium and at least one cell within each microwell. Surface tension at a non-polar/polar medium interface prevents molecule exchange between interior and exterior portions of microwells.
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128.发明授权公开(公告)号：US11364321B2
公开(公告)日：2022-06-21
申请号：US16157956
申请日：2018-10-11
Applicant: Arizona Board of Regents on Behalf of Arizona State University , The United States of America as Represented by The Department of Veterans Affairs
Inventor： Mehdi Nikkhah , Ali Navaei , Raymond Migrino
Abstract: A scaffold-free microtissue is disclosed that includes one or more gold nanostructures linked to a functional moiety, wherein the functional moiety is one or more vasculogenic peptides, one or more anti-inflammatory peptides, one or more antiapoptotic peptides, one or more antinecrotic peptides, one or more antioxidant peptides, one or more oligonucleotides, one or more lipid particles, one or more phospholipid particles, one or more liposomes, one or more nanoliposomes, one or more microRNAs, or one or more siRNAs. The scaffold-free microtissue further includes a plurality of cardiac myocytes or cardiac myoblasts, which are conjugated to the one or more gold nanostructures, wherein the plurality of cardiac myocytes or cardiac myoblasts are arranged in a cluster. The scaffold-free microtissue further includes a plurality of fibroblasts, wherein the fibroblasts are arranged in at least one layer of fibroblasts that substantially surrounds the cluster of gold-nanostructure-conjugated cardiac myocytes or gold-nanostructure-conjugated cardiac myoblasts.
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公开(公告)号：US11357848B2
公开(公告)日：2022-06-14
申请号：US15863118
申请日：2018-01-05
Inventor： Yung Chang , Sidney Hecht , Joseph Leal , Viswanath Arutla , Xiaowei Liu , Sriram Sokalingam
IPC: A61K39/385 , C07D401/14 , G16B15/00 , G16B20/00 , A61K47/64 , G01N33/94 , A61K39/00 , G16B15/30 , G16B20/30
Abstract: Provided herein are methods for rational design of nicotine haptens. More particularly, provided herein are methods for designing, selecting, and synthesizing nicotine haptens and nicotine hapten conjugates. Also provided herein are novel nicotine haptens and methods for using nicotine haptens to treat nicotine addiction.
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公开(公告)号：US11357801B2
公开(公告)日：2022-06-14
申请号：US16306240
申请日：2017-06-14
Inventor： James Adams , Dae-Wook Kang , Rosa Krajmalnik-Brown
IPC: A61K35/741 , A61K35/745 , A61K35/74
Abstract: The present disclosure relates to compositions and methods for treating autism spectrum disorder (ASD) by restoring an ASD patient's gut microbiota. These methods can be used with ASD patient with or without ongoing gastrointestinal symptoms. Provided here is a method for modulating the abundance of one or more gut microorganisms in a subject in need thereof, said method comprising administering to said subject a therapeutically effective amount of a pharmaceutical composition comprising a fecal microbe preparation to achieve at least a 2-fold change of the abundance of said one or more fecal microorganisms, wherein said one or more gut microorganisms are selected from the group consisting of Bifidobacterium, Prevotella, Desulfovibrio, Copprococcus, Clostridium, and Bacteroides.
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