公开(公告)号：US20240407804A1

公开(公告)日：2024-12-12

申请号：US18403328

申请日：2024-01-03

Applicant: Board of Regents of the University of Nebraska

Inventor： Thomas Frederick ,  Shane Farritor ,  Jack Mondry ,  Eric Markvicka ,  Dmitry Oleynikov ,  Jacob Greenburg

IPC: A61B17/34 ,  A61B17/00 ,  A61B17/02 ,  A61B34/30 ,  A61B90/00 ,  A61B90/40 ,  A61B90/50

Abstract: The various embodiments herein relate to systems, devices, and/or methods relating to surgical procedures, and more specifically for accessing an insufflated cavity of a patient and/or positioning surgical systems or devices into the cavity.

公开(公告)号：US20240390085A1

公开(公告)日：2024-11-28

申请号：US18794388

申请日：2024-08-05

Applicant: Board of Regents of the University of Nebraska

Inventor： Shane Farritor ,  Tom Frederick ,  Kearney Lackas ,  Joe Bartels ,  Jacob Greenburg

IPC: A61B34/30 ,  A61B34/00 ,  A61B90/00 ,  B25J9/16

Abstract: The various embodiments herein relate to robotic surgical systems and devices that use force and/or torque sensors to measure forces applied at various components of the system or device. Certain implementations include robotic surgical devices having one or more force/torque sensors that detect or measure one or more forces applied at or on one or more arms. Other embodiments relate to systems having a robotic surgical device that has one or more sensors and an external controller that has one or more motors such that the sensors transmit information that is used at the controller to actuate the motors to provide haptic feedback to a user.

公开(公告)号：US12096999B2

公开(公告)日：2024-09-24

申请号：US17880823

申请日：2022-08-04

Applicant: Board of Regents of the University of Nebraska

Inventor： Tom Frederick ,  Eric Markvicka ,  Shane Farritor ,  Dmitry Oleynikov

IPC: A61B34/30 ,  A61B18/14 ,  B25J9/00 ,  B25J9/04 ,  B25J9/10 ,  A61B17/00 ,  A61B18/00 ,  A61B18/08 ,  A61B18/12

CPC classification number: A61B34/30 ,  A61B18/14 ,  B25J9/0087 ,  B25J9/046 ,  B25J9/102 ,  A61B2017/00398 ,  A61B2017/00407 ,  A61B2017/00477 ,  A61B2018/00595 ,  A61B18/082 ,  A61B2018/1253 ,  A61B2018/1422 ,  A61B18/1445 ,  A61B2034/305 ,  A61B2217/005 ,  A61B2217/007 ,  A61B2218/002 ,  A61B2218/007

Abstract: The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices.

公开(公告)号：US20240294572A1

公开(公告)日：2024-09-05

申请号：US18278865

申请日：2022-04-22

Applicant: Board of Regents of the University of Nebraska

Inventor： Guangshun Wang ,  Radha M. Golla ,  Jayaram Lakshmaiah Narayana

IPC: C07K7/08 ,  A61K38/00 ,  A61K47/54 ,  A61P31/04 ,  C07K5/11

CPC classification number: C07K7/08 ,  A61K47/542 ,  A61P31/04 ,  C07K5/1019 ,  A61K38/00

Abstract: Antimicrobial peptides and methods of use are provided.

公开(公告)号：US20240216761A1

公开(公告)日：2024-07-04

申请号：US18563817

申请日：2022-06-24

Applicant: Board of Regents of the University of Nebraska

Inventor： Brian Knarr ,  Travis Vanderheyden ,  Russell Buffum

IPC: A63B24/00 ,  A63B22/02

CPC classification number: A63B24/0087 ,  A63B22/025 ,  A63B24/0021 ,  A63B2024/0025 ,  A63B2024/0093 ,  A63B2220/10 ,  A63B2220/30 ,  A63B2220/805 ,  A63B2220/833

Abstract: A system for controlling exercise equipment based on user pace and motion analysis is disclosed. The system includes a control unit communicatively coupled with a center of mass (COM) sensor and one or more additional sensors. The COM sensor is configured to track a position of a body of a user on the exercise equipment over time. The one or more additional sensors are configured to track off-center movements of the user over time. The control unit is configured to modulate an adjustable parameter of the exercise equipment based on a plurality of measurements of the user's body position and off-center movements collected by the COM sensor and the one or more additional sensors over time.

公开(公告)号：US20240123034A1

公开(公告)日：2024-04-18

申请号：US17768514

申请日：2020-10-15

Applicant: ModernaTX, Inc. ,  BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA

Inventor： Eric Yi-Chun Huang ,  Jared Iacovelli ,  Seymour De Picciotto ,  Sze-Wah Tse ,  Laurie Kenney ,  Katherine Olson ,  Howard Gendelman ,  Lee R. Mosley

IPC: A61K38/19 ,  A61K9/51 ,  A61K31/7115 ,  A61P25/16

CPC classification number: A61K38/193 ,  A61K9/5123 ,  A61K31/7115 ,  A61P25/16

Abstract: The disclosure features lipid nanoparticle (LNP) compositions comprising mRNA molecules encoding human granulocyte macrophage colony stimulating factor (GM-CSF) polypeptides and uses thereof in the treatment of Parkinson's Disease. The LNP compositions of the present disclosure comprise mRNA therapeutics encoding human GM-CSF for use in such treatment.

公开(公告)号：US11951227B2

公开(公告)日：2024-04-09

申请号：US17712601

申请日：2022-04-04

Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA

Inventor： Jingwei Xie ,  Shixuan Chen ,  Mark Carlson

IPC: A61L24/04 ,  A61K9/70 ,  A61L24/00 ,  A61L24/10 ,  A61L27/18 ,  A61L27/22 ,  A61L27/34 ,  A61L27/52 ,  A61L27/54 ,  D01D5/00 ,  D06M11/01 ,  D06M101/32 ,  D06N3/00

CPC classification number: A61L24/046 ,  A61K9/7007 ,  A61L24/0015 ,  A61L24/0031 ,  A61L24/104 ,  A61L27/18 ,  A61L27/222 ,  A61L27/34 ,  A61L27/52 ,  A61L27/54 ,  D01D5/0007 ,  D06M11/01 ,  A61L2300/404 ,  A61L2300/414 ,  A61L2300/418 ,  A61L2400/04 ,  A61L2400/12 ,  D06M2101/32 ,  D06N3/0004 ,  D06N2203/026 ,  D06N2203/028 ,  D06N2203/041 ,  D10B2509/022 ,  A61L24/046 ,  C08L67/04

Abstract: Coated and expanded, nanofiber structures are provided and methods of use thereof.

公开(公告)号：US11911464B2

公开(公告)日：2024-02-27

申请号：US17275892

申请日：2019-09-13

Applicant: Prommune, Inc. ,  Board of Regents of the University of Nebraska

Inventor： Paul Davis ,  Samer Al-Murrani

IPC: A61K39/39 ,  A61P33/02 ,  A61K39/002 ,  A61K39/005 ,  A61K39/008 ,  A61K39/012 ,  A61K39/015 ,  A61K39/018 ,  A61K39/00

CPC classification number: A61K39/39 ,  A61K39/002 ,  A61K39/005 ,  A61K39/008 ,  A61K39/012 ,  A61K39/015 ,  A61K39/018 ,  A61P33/02 ,  A61K2039/55516 ,  A61K2039/6031 ,  A61K2039/627

Abstract: Anti-parasitic compounds and uses thereof. Compounds comprising a C-terminal peptide adjuvant conjugated to an N-terminal peptide antigen via a protease-cleavable linker, said peptide adjuvant comprising a peptide analog of C5a, wherein said peptide antigen comprises an antigenic epitope of a parasitic organism, such as T. gondii. Methods of therapeutic or prophylactic treatment of a parasitic infections.

公开(公告)号：US11909576B2

公开(公告)日：2024-02-20

申请号：US18158810

申请日：2023-01-24

Applicant: Board of Regents of the University of Nebraska

Inventor： Shane Farritor ,  Tyler Wortman ,  Kyle Strabala ,  Ryan McCormick ,  Amy Lehman ,  Dmitry Oleynikov ,  Eric Markvicka

IPC: B25J9/02 ,  H04L41/0631 ,  A61B90/30 ,  B25J9/00 ,  B25J9/06 ,  A61B34/30 ,  H04L43/08 ,  A61B90/00

CPC classification number: H04L41/0631 ,  A61B34/30 ,  A61B90/30 ,  B25J9/0087 ,  B25J9/06 ,  H04L43/08 ,  A61B90/361 ,  A61B2034/302 ,  G05B2219/40418 ,  Y10S901/02 ,  Y10S901/19

Abstract: Various medical devices and related systems, including robotic and/or in vivo medical devices, and various robotic surgical devices for in vivo medical procedures. Included herein, for example, is a robotic surgical system having a support beam positionable through an incision, and a robotic device having a device body, first and second rotating shoulder components coupled to the device body, and first and second robotic arms coupled to the first and second shoulder components, respectively.

公开(公告)号：US20240033022A1

公开(公告)日：2024-02-01

申请号：US18482994

申请日：2023-10-09

Applicant: Board of Regents of the University of Nebraska

Inventor： Shane Farritor ,  Thomas Frederick ,  Joe Bartels ,  Eric Markvicka ,  Jack Mondry

IPC: A61B34/30

CPC classification number: A61B34/30 ,  Y10S901/28 ,  A61B2034/302

Abstract: The various embodiments disclosed herein relate to improved robotic surgical systems, including robotic surgical devices having improved arm components and/or biometric sensors, contact detection systems for robotic surgical devices, gross positioning systems and devices for use in robotic surgical systems, and improved external controllers and consoles.