公开(公告)号：US10441445B2

公开(公告)日：2019-10-15

申请号：US15429339

申请日：2017-02-10

Applicant: Abbott Cardiovascular Systems, Inc.

Inventor： Pamela A. Kramer-Brown ,  Kayla L. Calvert ,  John A. Simpson ,  Stephen D. Pacetti ,  Austin M. Leach

IPC: C22C19/07 ,  A61F2/82 ,  A61F2/06 ,  A61L31/02 ,  A61L31/18 ,  C22C1/04 ,  C22C19/05 ,  C22C27/00 ,  C22C27/04 ,  C22C27/06

Abstract: Embodiments are directed to radiopaque implantable structures (e.g., stents) formed of cobalt-based alloys that comprise cobalt, chromium and one or more platinum group metals, refractory metals, precious metals, or combinations thereof. Platinum group metals include platinum, palladium, ruthenium, rhodium, osmium, and iridium. Refractory metals include zirconium, niobium, rhodium, molybdenum, hafnium, tantalum, tungsten, rhenium, and precious metals include silver and gold. In one embodiment, the one or more included platinum group or refractory metals substitute at least partially for nickel, such that the alloy exhibits reduced nickel content, or is substantially nickel free. The stents exhibit improved radiopacity as compared to similar alloys including greater amounts of nickel.

公开(公告)号：US20190110914A1

公开(公告)日：2019-04-18

申请号：US16218272

申请日：2018-12-12

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Annie P. Liu ,  Mark C. Johnson

IPC: A61F2/958 ,  A61L31/06 ,  A61L31/14 ,  A61F2/82 ,  A61F2/962 ,  A61L31/04

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath is removed by a health professional either by removing the sheath directly or using a tube containing the catheter.

公开(公告)号：US20180154051A1

公开(公告)日：2018-06-07

申请号：US15797218

申请日：2017-10-30

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Syed F.A. Hossainy ,  Fuh-Wei Tang ,  Lothar W. Kleiner ,  Thierry Glauser ,  Yiwen Tang ,  Wouter E. Roorda ,  Stephen D. Pacetti ,  Gina Zhang ,  Yung-Ming Chen ,  Andrew F. McNiven ,  Sean A. McNiven ,  Brandon J. Yoe

IPC: A61L31/10 ,  A61L27/54 ,  A61L31/16 ,  A61L27/40 ,  A61L27/44 ,  A61L27/50 ,  A61L31/12 ,  A61L31/14

CPC classification number: A61L31/10 ,  A61L27/40 ,  A61L27/44 ,  A61L27/50 ,  A61L27/54 ,  A61L31/12 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/00

Abstract: The present disclosure teaches methods of controlling the release rate of agents from a polymeric matrix that include designing and creating a predetermined initial morphology (IM) profile in a polymeric matrix. The teachings indicate, inter alia, that control over the release rate of agents can provide for an improved control over the administration of agents as well as have an effect upon the mechanical integrity and absorption rate of the polymeric matrix.

公开(公告)号：US09987154B2

公开(公告)日：2018-06-05

申请号：US15154801

申请日：2016-05-13

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Richard Rapoza

IPC: A61F2/82 ,  A61F2/89 ,  A61F2/915 ,  A61F2/91

CPC classification number: A61F2/89 ,  A61F2/82 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/9155 ,  A61F2230/0054 ,  Y10T29/49995

Abstract: An implantable stent includes a plurality of rings. At least a distal end ring has an eased corner feature formed in the polymer substrate at a radially outward, distal-facing corner of the ring while relatively sharp corners of the polymer substrate are maintained in radially inward corners of the ring.

公开(公告)号：US09949854B2

公开(公告)日：2018-04-24

申请号：US15598231

申请日：2017-05-17

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti

IPC: A61F2/958 ,  B21D39/04 ,  A61F2/06 ,  B05C11/00 ,  A61L31/02 ,  A61F2/82 ,  A61F2/07 ,  A61L31/16 ,  A61L31/04 ,  A61F2/95

CPC classification number: A61F2/958 ,  A61F2/06 ,  A61F2/07 ,  A61F2/82 ,  A61F2002/9522 ,  A61F2240/001 ,  A61L31/022 ,  A61L31/048 ,  A61L31/16 ,  A61L2300/416 ,  A61L2420/06 ,  B05C11/00 ,  B21D39/048 ,  Y10T29/49863 ,  Y10T29/49865 ,  Y10T29/49925 ,  Y10T29/49927 ,  Y10T29/53996

Abstract: A method for crimping a stent with a polymer coating in a humid environment is disclosed.

公开(公告)号：US20180008438A1

公开(公告)日：2018-01-11

申请号：US15688486

申请日：2017-08-28

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Rommel Lumauig ,  Stephen D. Pacetti ,  Ni Ding ,  Joel Harrington ,  Xiao Ma ,  James P. Oberhauser ,  Jill McCoy ,  Chad J. Abunassar ,  Senthil Eswaran ,  Diem Ta

IPC: A61F2/915 ,  B29C71/02 ,  C08G63/08 ,  A61L31/14 ,  A61L31/06 ,  B29L31/00 ,  B29C35/08 ,  B29C35/04 ,  B29K67/00

CPC classification number: A61F2/915 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2230/0069 ,  A61L31/06 ,  A61L31/14 ,  A61L31/148 ,  B29C71/0009 ,  B29C71/02 ,  B29C2035/046 ,  B29C2035/048 ,  B29C2035/0811 ,  B29C2035/0822 ,  B29C2035/0855 ,  B29C2035/0861 ,  B29C2071/022 ,  B29K2067/046 ,  B29K2995/006 ,  B29L2031/7534 ,  C08G63/08 ,  C08L67/04

Abstract: Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.

公开(公告)号：US09821091B2

公开(公告)日：2017-11-21

申请号：US13953656

申请日：2013-07-29

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Syed F. A. Hossainy ,  Fuh-Wei Tang ,  Lothar W. Kleiner ,  Thierry Glauser ,  Yiwen Tang ,  Wouter E. Roorda ,  Stephen D. Pacetti ,  Gina Zhang ,  Yung-Ming Chen ,  Andrew F. McNiven ,  Sean A. McNiven ,  Brandon J. Yoe

IPC: A61L31/10 ,  A61L27/40 ,  A61L27/44 ,  A61L27/50 ,  A61L27/54 ,  A61L31/12 ,  A61L31/14 ,  A61L31/16

CPC classification number: A61L31/10 ,  A61L27/40 ,  A61L27/44 ,  A61L27/50 ,  A61L27/54 ,  A61L31/12 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/00

Abstract: The present disclosure teaches methods of controlling the release rate of agents from a polymeric matrix. The methods relate to the application of pressure, and optionally, in combination with heat, to a polymeric coating.

公开(公告)号：US20170319363A1

公开(公告)日：2017-11-09

申请号：US15661925

申请日：2017-07-27

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Xiao Ma ,  Mary Beth Kossuth ,  James P. Oberhauser ,  Stephen D. Pacetti ,  Manish Gada

IPC: A61F2/90 ,  A61L31/06 ,  A61L31/04 ,  A61L31/14 ,  A61F2/91

CPC classification number: A61F2/90 ,  A61F2/91 ,  A61L31/041 ,  A61L31/06 ,  A61L31/148

Abstract: Bioresorbable polymer vascular scaffolds made of combinations of polylactide and polycaprolactone having a high molecular weight polymer, thin struts in a selected range and sufficient radial strength to support a vessel upon deployment. The scaffolds have degradation behavior of molecular weight, radial strength, and mass that are conducive to healing of a vessel including providing patency to a vessel, reduction of radial strength, breaking up, and resorbing to allow return of the vessel to a natural state.

公开(公告)号：US09795497B2

公开(公告)日：2017-10-24

申请号：US14859170

申请日：2015-09-18

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Rommel Lumauig ,  Stephen D. Pacetti ,  Ni Ding ,  Joel Harrington ,  Xiao Ma ,  James P. Oberhauser ,  Jill McCoy ,  Chad J. Abunassar ,  Senthil Eswaran ,  Diem Ta

IPC: A61F2/82 ,  A61F2/91 ,  A61F2/915 ,  C08G63/08 ,  B29C71/02 ,  A61L31/06 ,  A61L31/14 ,  B29K67/00 ,  B29L31/00 ,  B29C35/04 ,  B29C35/08

CPC classification number: A61F2/915 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2230/0069 ,  A61L31/06 ,  A61L31/14 ,  A61L31/148 ,  B29C71/0009 ,  B29C71/02 ,  B29C2035/046 ,  B29C2035/048 ,  B29C2035/0811 ,  B29C2035/0822 ,  B29C2035/0855 ,  B29C2035/0861 ,  B29C2071/022 ,  B29K2067/046 ,  B29K2995/006 ,  B29L2031/7534 ,  C08G63/08 ,  C08L67/04

Abstract: Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.

公开(公告)号：US09687239B2

公开(公告)日：2017-06-27

申请号：US14253719

申请日：2014-04-15

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Paul Consigny ,  Erik Eli ,  Stephen D. Pacetti ,  Mikael Trollsas ,  John Stankus ,  Julia Fox

IPC: A61F2/06 ,  A61B17/11 ,  A61F2/91 ,  A61F2/954 ,  A61F2/856 ,  A61F2/89 ,  A61F2/958 ,  A61M1/36 ,  A61F2/848 ,  A61F2/966 ,  A61F2/82 ,  A61F2/915

CPC classification number: A61B17/11 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61F2/064 ,  A61F2/848 ,  A61F2/856 ,  A61F2/89 ,  A61F2/91 ,  A61F2/954 ,  A61F2/958 ,  A61F2/966 ,  A61F2002/821 ,  A61F2002/828 ,  A61F2002/91575 ,  A61F2002/9583 ,  A61M1/3655

Abstract: Medical devices and methods for forming an arteriovenous (AV) fistula include a stent having an arterial tubular portion and vein supporting tongue connected by a pre-shaped connector and a venous frustoconical stent having a distal end for maintaining a take-off angle for the venous portion of the AV fistula. Also disclosed is an angled balloon for assisting with the formation of the AV fistula. The medical devices disclosed herein support an AV fistula formation having a desired take off angle of about 30 degrees, or between about 15 and 45 degrees.