Self-renewing pluripotent hepatic stem cells
    121.
    发明授权
    Self-renewing pluripotent hepatic stem cells 失效
    自我更新多能肝干细胞

    公开(公告)号:US07150990B2

    公开(公告)日:2006-12-19

    申请号:US10093311

    申请日:2002-03-06

    摘要: The present invention provides clonal pluripotent hepatic stem cells using flow cytometry and in vitro single-cell-based assays. These cells possess multilineage differentiation potential and self-renewing capability. These cells may be clonally propagated in culture, to continuously produce hepatocytes and cholangiocytes as descendants while maintaining primitive stem cells. When expanded cells are transplanted into recipient animals, they morphologically and functionally differentiated into hepatocytes and cholangiocytes, with reconstitution of hepatocyte and bile duct structures. Furthermore, these cells differentiated into pancreatic ductal and acinar cells or intestinal epithelial cells when transplanted into pancreas or duodenal wall. Thus, the self-renewing multipotent stem cells persist in the developing mouse liver and can be induced to become cells of other organs of endodermal origin under appropriate microenvironment, providing new insight into therapies for diseases of the digestive system.

    摘要翻译: 本发明使用流式细胞术和体外基于单细胞的测定法提供克隆多能肝干细胞。 这些细胞具有多谱分化潜能和自我更新能力。 这些细胞可以在培养物中克隆繁殖,以连续产生肝细胞和胆管细胞作为后代,同时保持原始干细胞。 当将扩增的细胞移植到受体动物中时,其形态和功能上分化为肝细胞和胆管细胞,重组肝细胞和胆管结构。 此外,当移植到胰腺或十二指肠壁时,这些细胞分化为胰腺导管和腺泡细胞或肠上皮细胞。 因此,自我更新的多能干细胞持续存在于发育中的小鼠肝脏中,并可在适当的微环境下诱导成为内胚层起源的其他器官的细胞,为消化系统疾病的治疗提供新的见解。

    Method for predicting protein-protein interactions
    124.
    发明申请
    Method for predicting protein-protein interactions 审中-公开
    蛋白质 - 蛋白质相互作用预测方法

    公开(公告)号:US20060069519A1

    公开(公告)日:2006-03-30

    申请号:US11291770

    申请日:2005-12-02

    IPC分类号: G06F19/00

    摘要: Method predicting whether protein or polypeptide interacts with another one by the steps of decomposition, database searching, sequence alignment and frequency determination; recording medium for carrying out the method; and obtained proteins.

    摘要翻译: 通过分解,数据库检索,序列比对和频率测定等步骤,预测蛋白质或多肽与另一种蛋白质相互作用的方法。 用于执行该方法的记录介质; 并获得蛋白质。

    Slider tester
    125.
    发明授权
    Slider tester 失效
    滑块测试仪

    公开(公告)号:US06943971B2

    公开(公告)日:2005-09-13

    申请号:US10348680

    申请日:2003-01-21

    摘要: The slider tester is capable of solely testing a slider and securely selecting good sliders so as to reduce wasteful costs. The slider tester, which tests reading and writing functions of a slider for reading data from and writing data on a recording medium, includes a testing device for testing the functions of the slider, and a setting plate holding the slider and electrically connecting the slider to the testing device. The setting plate separates the slider a prescribed distance from the recording medium during the test so as to read data from and write data on the recording medium, wherein the slider can be independently attached to and detached from the setting plate.

    摘要翻译: 滑块测试仪能够单独测试滑块并安全地选择好的滑块,以减少浪费的成本。 滑块测试器测试用于在记录介质上读取数据和将数据写入记录介质的滑块的读和写功能,包括用于测试滑块的功能的测试装置,以及夹持滑块并将滑块电连接到 测试设备。 在测试期间,设置板将滑块与记录介质分开规定距离,以便从记录介质上读取数据和写入数据,其中滑块可以独立地安装到设置板上并从设置板拆下。

    Coated optical fiber, optical fiber tape core using it and optical fiber unit
    126.
    发明授权
    Coated optical fiber, optical fiber tape core using it and optical fiber unit 有权
    涂层光纤,光纤带芯和光纤单元

    公开(公告)号:US06907175B2

    公开(公告)日:2005-06-14

    申请号:US10416027

    申请日:2002-02-20

    摘要: The present invention provides a coated optical fiber in which a silica type optical fiber is coated with n layers (n being an integer of 2 or greater) of UV-curable resin, wherein the sum of respective contraction stress indices FI defined in the n layers of UV-curable resin by the following expression: FI [N]=(Young's modulus [MPa] of the UV-curable resin layer at −40° C.)×(cross-sectional area [mm2] of the UV-curable resin layer)×(effective linear expansion coefficient [10−6/° C.]/106)×(temperature difference 190[° C.]) is 3 [N] or less. The present invention can sufficiently prevent transmission characteristics from deteriorating in a low temperature environment.

    摘要翻译: 本发明提供了一种涂覆光纤,其中二氧化硅型光纤被涂覆有n层(n为2以上的整数)的UV固化树脂,其中在n层中限定的各个收缩应力指数FI的总和 通过以下表达式得到紫外线固化树脂:FI [N] =(-40℃下UV固化树脂层的杨氏模量[MPa])×(截面积[mm 2] >](有效线膨胀系数[10 -6 /℃] / 10 6)×(温度差190° C.])为3 [N]以下。 本发明可以充分防止低温环境下的传输特性劣化。

    Optical disk reproducing apparatus, and offset adjustment method
    127.
    发明申请
    Optical disk reproducing apparatus, and offset adjustment method 审中-公开
    光盘再现装置和偏移调整方法

    公开(公告)号:US20050063287A1

    公开(公告)日:2005-03-24

    申请号:US10941555

    申请日:2004-09-15

    IPC分类号: G11B7/00 G11B7/09

    摘要: When a gain control circuit is its maximum gain, an offset adjusting circuit generates an offset adjusting voltage so that an offset voltage included in an output signal of this gain control circuit becomes a target voltage within a dynamic range of a digital correction unit, and a control circuit adjusts an offset by adding the offset adjusting voltage to a control signal from a processing circuit in an adding circuit. In this case, a residual offset voltage included in an output signal of this gain control circuit is corrected by a digital correction unit. All of the electrical offset in the analog circuitry are not cancelled, but the offset adjustment is carried out to a range correctable by the digital correction circuit.

    摘要翻译: 当增益控制电路是其最大增益时,偏移调整电路产生偏移调整电压,使得包括在该增益控制电路的输出信号中的偏移电压成为数字校正单元的动态范围内的目标电压, 控制电路通过将偏移调整电压加到来自加法电路中的处理电路的控制信号来调整偏移。 在这种情况下,通过数字校正单元校正包含在该增益控制电路的输出信号中的残留偏移电压。 模拟电路中的所有电气偏移量都不会被取消,而是通过数字校正电路进行偏移调整。

    Method of treating surface of face panel for image display
    129.
    发明授权
    Method of treating surface of face panel for image display 失效
    用于图像显示的面板表面处理方法

    公开(公告)号:US06669524B2

    公开(公告)日:2003-12-30

    申请号:US09813202

    申请日:2001-03-20

    IPC分类号: H01J2928

    摘要: In a method of treating a surface of a face panel for an image display including forming a film on the surface using coating materials, the film is formed of at least two layers including a first layer formed by a spray coating method and a second layer formed by a spin coating method to be superposed on the first layer. Thus, a face plate having antireflection/antistatic effects and providing high-resolution images can be obtained with high efficiency.

    摘要翻译: 在一种处理用于图像显示面板的表面的方法中,包括使用涂层材料在表面上形成膜,该膜由至少两层形成,包括通过喷涂法形成的第一层和形成的第二层 通过旋涂法叠加在第一层上。 因此,可以高效率地获得具有抗反射/抗静电效果并提供高分辨率图像的面板。

    Ink jet printer
    130.
    发明授权

    公开(公告)号:US06663220B2

    公开(公告)日:2003-12-16

    申请号:US09921568

    申请日:2001-08-06

    IPC分类号: B41J1165

    摘要: A discharge port is formed in a bottom surface of ink tank. The ink tank is made to communicate with a waste ink tank by connecting the discharge port to the waste ink tank in a position lower than the discharge port, and a part of connection member is openable/closable by a valve. If the connection member is opened, ink is discharged from the discharge port of the ink tank to the waste ink tank. If impurities are deposited on the bottom surface of the ink tank, the impurities can be discharged with ink from the discharge port to the waste ink tank, thereby clogging in the nozzle head due to impurities can be reliably prevented.