公开(公告)号：US06643984B2

公开(公告)日：2003-11-11

申请号：US09978677

申请日：2001-10-18

申请人： Kenji Kato ,  Yoshinobu Yamamoto ,  Takanobu Kondo ,  Nobuyuki Tanaka

发明人： Kenji Kato ,  Yoshinobu Yamamoto ,  Takanobu Kondo ,  Nobuyuki Tanaka

IPC分类号： E06B3988

CPC分类号： B60J1/10 ,  B60J10/16 ,  B60J10/50 ,  B60J10/70

摘要： A frame-attached window panel wherein a frame member comprises a base portion attached firmly to a peripheral portion of a window panel and a primary molding molded integrally with the base portion, and the primary molding is made of a material different from the material for the base portion. The generation of noises can be suppressed by the presence of the frame member which can be formed at low cost.

摘要翻译： 一种框架连接的窗板，其中框架构件包括牢固地附接到窗口板的周边部分的基部和与基部一体成型的一次成型，并且一次成型由与用于 基部。 可以通过可以以低成本形成的框架构件的存在来抑制噪声的产生。

公开(公告)号：US06430366B1

公开(公告)日：2002-08-06

申请号：US08701676

申请日：1996-08-22

申请人： Masataka Mizutani ,  Nobuyuki Tanaka ,  Atsushi Sawaki

发明人： Masataka Mizutani ,  Nobuyuki Tanaka ,  Atsushi Sawaki

IPC分类号： E03D908

CPC分类号： E03D9/08

摘要： One hundred volt AC power is conducted from a plug to a heater of a water tank through 100V lines. The 100V lines are provided with an electricity supply controlling element. Direct current 5V is conducted from the 100V lines to a microcomputer 15 through a power-supply circuit formed with a transformer, a rectifier circuit and the like. The electricity supply controlling element receives a control signal through the signal line to keep the water temperature in the water tank at a predetermined temperature. The signal line is provided with a tipover switch and a float switch on the way thereof, thereby securely stopping the operation of the electricity supply controlling element when the water tank is tilted or turned over. The tipover switch is one with a smaller capacity, thereby reducing its cost.

摘要翻译： 通过100V线路将100伏交流电源从插头传输到水箱的加热器。 100V线路配备有供电控制元件。 通过形成有变压器，整流电路等的电源电路，将直流5V从100V线路传送到微型计算机15。 供电控制元件通过信号线接收控制信号，以将水箱中的水温保持在预定温度。 信号线在其路上设置有翻转开关和浮子开关，从而当水箱倾斜或翻转时可靠地停止供电控制元件的操作。 翻转开关是具有较小容量的翻转开关，从而降低其成本。

公开(公告)号：US06376707B1

公开(公告)日：2002-04-23

申请号：US09889857

申请日：2001-07-23

申请人： Michio Toda ,  Tetsuro Tamai ,  Nobuyuki Tanaka ,  Kiyoshi Kasai ,  Junichi Sonehara ,  Eiji Tsuru

发明人： Michio Toda ,  Tetsuro Tamai ,  Nobuyuki Tanaka ,  Kiyoshi Kasai ,  Junichi Sonehara ,  Eiji Tsuru

IPC分类号： C07C22900

CPC分类号： C07C217/60 ,  C07C213/10

摘要： The present invention relates to a crystalline polymorph of 2-[4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxy-phenyl)-1-methylethyl]amino]ethyl]phenoxy]acetic acid having strong diffraction peaks (diffraction angle: 2&thgr;±0.1°) at 10.8, 19.1, 19.3, 19.8, 20.6 and 27.0° in powder X-ray diffraction pattern, which has potent &bgr;2- and &bgr;3-adrenoceptor stimulating effects and is useful as an agent for relieving pain and promoting the removal of calculi in urolithiasis, and the like. For example, the crystalline polymorph can be prepared by hydrolyzing ethyl 2-[4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]-amino]ethyl]phenoxy]acetate phosphate by sodium hydroxide, adding an aqueous phosphoric acid solution at 40° C. and over, adding a mixed solvent of water and methanol or methanol to the resulting compound, and stirring the suspension at 40° C. to reflux temperature for 30 minutes to several hours.

摘要翻译： 本发明涉及2- [4- [2 - [[（1S，2R）-2-羟基-2-（4-羟基 - 苯基）-1-甲基乙基]氨基]乙基]苯氧基]乙酸的结晶多晶型物 在其粉末X射线衍射图中，在10.8,19.1,19.3,19.8,20.6和27.0°处具有强衍射峰（衍射角：2θ±0.1°）的酸，其具有有效的β2-和β3-肾上腺素受体刺激作用，并且是有用的 作为缓解疼痛并促进尿石结石中的结石的去除的药剂等。 例如，结晶多晶型物可以通过水解2- [4- [2 - [[（1S，2R）-2-羟基-2-（4-羟基苯基）-1-甲基乙基] - 氨基]乙基]苯氧基 ]乙酸磷酸盐与氢氧化钠反应，在40℃加入磷酸水溶液，过滤，向所得化合物中加入水和甲醇或甲醇的混合溶剂，并在40℃下将悬浮液在回流温度下搅拌30 几分钟到几个小时。

公开(公告)号：US06353025B1

公开(公告)日：2002-03-05

申请号：US09581851

申请日：2000-06-19

申请人： Tetsuro Tamai ,  Nobuyuki Tanaka ,  Harunobu Mukaiyama ,  Akihito Hirabayashi ,  Hideyuki Muranaka ,  Masaaki Sato ,  Masuo Akahane

发明人： Tetsuro Tamai ,  Nobuyuki Tanaka ,  Harunobu Mukaiyama ,  Akihito Hirabayashi ,  Hideyuki Muranaka ,  Masaaki Sato ,  Masuo Akahane

IPC分类号： A01N3712

CPC分类号： C07D295/185 ,  C07C229/18 ,  C07C237/06

摘要： The present invention provides novel phenylaminoalkyl-carboxylic acid derivatives represented by the general formula: (wherein R1 represents a hydroxy group, a lower alkoxy group, an aralkoxy group, an amino group, an alicyclic amino group or a mono or di(lower alkyl)amino group which may have a hydroxy group or a lower alkoxy group as a substituent; R2 represents a hydrogen atom or a lower alkyl group; R3 represents a hydrogen atom or a halogen atom; R4 and R5 are the same or different and each represents a hydrogen atom, a halogen atom or a lower alkyl group; A represents a lower alkylene group; the carbon atom marked with (R) represents a carbon atom in (R) configuration; and the carbon atom marked with (S) represents a carbon atom in (S) configuration) and pharmaceutically acceptable salts thereof, which have excellent &bgr;3-adrenoceptor stimulating effects and are useful as agents for the prevention or treatment of obesity, hyperglycemia, the diseases caused by intestinal hypermotility, pollakiuria, urinary incontinence, depression, or the diseases caused by biliary calculi or hypermotility of biliary tract.

摘要翻译： 本发明提供由通式（其中R1表示羟基，低级烷氧基，芳烷氧基，氨基，脂环族氨基或单或二（低级烷基））表示的新型苯基氨基烷基 - 羧酸衍生物， 可以具有羟基或低级烷氧基作为取代基的氨基; R2表示氢原子或低级烷基; R3表示氢原子或卤素原子; R4和R5相同或不同，表示 氢原子，卤素原子或低级烷基; A表示低级亚烷基;（R）表示的碳原子表示（R）构型的碳原子，（S）表示的碳原子表示碳原子 （S）构型）及其药学上可接受的盐，其具有优异的β3肾上腺素能受体刺激作用，并且可用作预防或治疗肥胖症，高血糖症，由肠道超嗜热引起的疾病 遗尿，尿频，尿失禁，抑郁症或由胆汁结石或胆汁运动障碍引起的疾病。

公开(公告)号：US6136852A

公开(公告)日：2000-10-24

申请号：US155345

申请日：1999-03-08

申请人： Makio Kitazawa ,  Kosuke Okazaki ,  Tetsuro Tamai ,  Masaru Saito ,  Nobuyuki Tanaka ,  Hiroaki Kobayashi ,  Ken Kikuchi ,  Hideyuki Muranaka

发明人： Makio Kitazawa ,  Kosuke Okazaki ,  Tetsuro Tamai ,  Masaru Saito ,  Nobuyuki Tanaka ,  Hiroaki Kobayashi ,  Ken Kikuchi ,  Hideyuki Muranaka

IPC分类号： C07C217/74 ,  C07C229/46 ,  C07C229/50 ,  A61K31/215 ,  A61K31/19 ,  C07C62/06 ,  C07C69/76

CPC分类号： C07C229/50 ,  C07C217/74 ,  C07C2102/10 ,  Y02P20/55

摘要： The present invention relates to 3,4-disubstituted phenylethanolaminotetralincarboxylic acid derivatives represented by the general formula: ##STR1## [wherein Q represents a vinylene group or a group represented by the general formula:-A-(CH.sub.2).sub.m --(wherein A represents an oxygen atom or a methylene group; and m is an integer of from 1 to 6); R represents a hydrogen atom or a lower alkyl group; n is an integer of 1 or 2; the carbon atom marked with * represents a carbon atom in R configuration, S configuration or a mixture thereof; and the carbon atom marked with (S) represents a carbon atom in S configuration] and pharmaceutically acceptable salts thereof, which have a selective .beta..sub.2 -adrenergic receptor stimulating effect with relieved burdens on the heart such as tachycardia and are useful as an agent for the prevention of threatened abortion and premature labor, a bronchodilator and an agent for pain remission and promoting stone removal in urolithiasis.

摘要翻译： PCT No.PCT / JP97 / 01008 Sec。 371日期1999年3月8日 102（e）1999年3月8日PCT 1997年3月26日PCT公布。 公开号WO97 / 35835 日期：1997年10月2日本发明涉及由以下通式表示的3,4-二取代苯乙醇氨基四氢萘羧酸衍生物：[其中Q表示亚乙烯基或由通式-A-（CH 2）m - 表示的基团 A表示氧原子或亚甲基; m表示1〜6的整数）; R表示氢原子或低级烷基; n为1或2的整数; 标有*的碳原子表示R构型，S构型或其混合物中的碳原子; 标记有（S）的碳原子表示S构型的碳原子及其药学上可接受的盐，其具有选择性β2-肾上腺素能受体刺激作用，并且在心脏上缓解负担，例如心动过速，并且可用作 防止威胁堕胎和早产，支气管扩张剂和止痛剂，促进尿石症中的除石。

公开(公告)号：US5870645A

公开(公告)日：1999-02-09

申请号：US892481

申请日：1997-07-14

申请人： Yasuo Tanbara ,  Nobuyuki Tanaka

发明人： Yasuo Tanbara ,  Nobuyuki Tanaka

IPC分类号： G03B17/00 ,  G03B9/08 ,  G03B17/02

CPC分类号： G03B17/02

摘要： A camera for use with a compact film cartridge having a battery arranged in the front end portion of a grip portion, and a cartridge chamber in which a compact film cartridge is stored is arranged at the boundary between the grip portion and a camera body. A motor is arranged between the battery and the cartridge chamber. A main capacitor for causing an electronic flash to emit light is horizontally arranged above the cartridge chambers and motor. In the camera arranged as described above, although the camera body and a lens barrel are smaller than those of a conventional camera in order to achieve miniaturization commensurate with miniaturization of the film, the grip portion has a size and height which are equal to those of the grip portion of the conventional camera. Accordingly, in the camera, of the present invention a release operation can be easily performed, and a shape having good holding properties can be obtained.

摘要翻译： 一种用于与具有设置在把手部分的前端部分中的电池的紧凑型暗盒一起使用的照相机和其中存储有小型暗盒的暗盒室布置在抓握部分和照相机主体之间的边界处。 在电池和暗盒之间布置电动机。 用于使电子闪光灯发光的主电容器水平地布置在盒室和电动机的上方。 在如上所述配置的相机中，虽然相机体和透镜镜筒比传统照相机小，但是为了实现与胶片的小型化相称的小型化，把手部分的尺寸和高度等于 常规照相机的把手部分。 因此，在本发明的照相机中，可以容易地进行释放操作，并且可以获得具有良好保持性的形状。

公开(公告)号：US5838519A

公开(公告)日：1998-11-17

申请号：US928922

申请日：1997-09-12

申请人： Toshimitsu Takizawa ,  Takahiro Asano ,  Nobuyuki Tanaka

发明人： Toshimitsu Takizawa ,  Takahiro Asano ,  Nobuyuki Tanaka

IPC分类号： G11B21/02 ,  G11B5/48 ,  H05K1/02 ,  H05K1/11 ,  H05K1/14 ,  H05K3/34 ,  H05K3/36 ,  H05K3/40 ,  G11B5/55

CPC分类号： G11B5/486 ,  H05K3/363 ,  H05K1/0206 ,  H05K1/0212 ,  H05K1/113 ,  H05K2201/0367 ,  H05K2201/09563 ,  H05K2201/09572 ,  H05K2201/10666 ,  H05K2201/10734 ,  H05K2201/10992 ,  H05K3/3473 ,  H05K3/3494 ,  H05K3/4007

摘要： A bump of an electrically conductive metal protrudes from an electrode pad of a junction FPC. The bump includes a lead portion that penetrates a conductor pattern and a base layer of the junction FPC and projects on the back side of the base layer. A spare solder layer is formed on the surface of the bump. In soldering the electrode pad of the junction FPC to a connecting pad of a main FPC, the bump and the connecting pad are opposed to each other, and a heat source is pressed against the lead portion of the bump from the side of the base layer of the junction FPC. Heat is transmitted to the spare solder layer through the lead portion and the bump, whereupon the spare solder layer is melted for soldering.

摘要翻译： 导电金属的凸起从接合FPC的电极焊盘突出。 凸块包括穿过导体图案的引线部分和接合FPC的基底层并突出在基底层的背面上。 在凸块的表面上形成备用焊料层。 在将FPC的电极焊盘焊接到主FPC的连接焊盘的同时，凸起和连接焊盘彼此相对，并且热源从基层的一侧压靠在凸块的引线部分 的FPC。 热量通过引线部分和凸块传输到备用焊料层，随后将备用焊料层熔化以进行焊接。

公开(公告)号：US5807836A

公开(公告)日：1998-09-15

申请号：US393565

申请日：1995-02-23

申请人： Tadatsugu Taniguchi ,  Cheryl L. Willman ,  Maria G. Pallavicini ,  Hisashi Harada ,  Nobuyuki Tanaka

发明人： Tadatsugu Taniguchi ,  Cheryl L. Willman ,  Maria G. Pallavicini ,  Hisashi Harada ,  Nobuyuki Tanaka

IPC分类号： G01N33/68 ,  A61K31/70 ,  A61K35/12 ,  A61K38/00 ,  A61K39/395 ,  A61K48/00 ,  A61P35/00 ,  C07H21/04 ,  C07K14/47 ,  C12N15/09 ,  C12Q1/68 ,  A01N43/04

CPC分类号： C12Q1/6841 ,  C07K14/4702 ,  C12Q1/6809 ,  C12Q1/6886 ,  A61K38/00 ,  C12N2799/027 ,  C12Q2600/156 ,  C12Q2600/158

摘要： The present invention relates, in general, to a method of diagnosing tumorigenic mammalian cells or the propensity of a mammalian cell to become tumorigenetic. Additionally, the present invention relates to a cloned cDNA or genomic DNA for reducing the propensity of a cell to become tumorigenic or suppressing tumorigenic phenotype of a cell; a method of reducing the propensity of a cell to become tumorigenic or suppressing the tumorigenic phenotype of a cell; a method of treating a patient suffering from or predisposed to subsequent cancer development; and a method of diagnosing tumorigenic tissue of a human or tissue predisposed to become tumorigenic.

摘要翻译： 本发明一般涉及诊断致瘤性哺乳动物细胞的方法或哺乳动物细胞变得致瘤性的倾向。 此外，本发明涉及用于降低细胞变得致瘤性或抑制细胞致瘤表型的倾向的克隆的cDNA或基因组DNA; 减少细胞变得致瘤性或抑制细胞的致瘤表型的倾向的方法; 治疗患有或易患随后的癌症发展的患者的方法; 以及诊断倾向于致瘤的人或组织的致瘤组织的方法。

公开(公告)号：US5742615A

公开(公告)日：1998-04-21

申请号：US667145

申请日：1996-06-20

申请人： Ichiro Kondo ,  Nobuyuki Tanaka

发明人： Ichiro Kondo ,  Nobuyuki Tanaka

IPC分类号： G11C17/00 ,  G11C16/02 ,  G11C16/06 ,  G11C16/16 ,  G11C16/34 ,  G11C29/34 ,  G01R31/28

CPC分类号： G11C16/3409 ,  G11C16/16 ,  G11C16/3404 ,  G11C29/34

摘要： In order to shorten initialization time, a flash type non-volatile semiconductor memory of the invention comprises a line decoder (2) for selecting all of word lines (WL1 to WLm), a word line voltage generator (3) for generating various voltage, a column decoder (4) for selecting or not selecting all of digit lines (DL1 to DLn). Erase pulse impression process is performed by supplying a positive first word line voltage to all the word lines (WL1 to WLm) selected, and an erase voltage (Vs) to a source line, leaving all the digit line floating. All of memory-cell-transistors (MC11 to MCmn) are erased by infusing hot carriers in their floating gates by way of avalanche breakdown caused between their sources and substrates. Depression discrimination is performed with a sense amplifier (8) by selecting all digit lines (DL1 to DLn) and supplying all word lines (WL1 to WLm) with a second word line voltage.

摘要翻译： 为了缩短初始化时间，本发明的闪存式非易失性半导体存储器包括用于选择字线（WL1〜WLm）的全部行线路解码器（2），用于产生各种电压的字线电压发生器（3） 用于选择或不选择所有数字行（DL1至DLn）的列解码器（4）。 通过向所选择的所有字线（WL1至WLm）提供正的第一字线电压以及向源极线提供擦除电压（Vs），使所有数字线浮动，从而执行擦除脉冲压印处理。 所有存储单元晶体管（MC11至MCmn）都可通过在源极和衬底之间引起的雪崩击穿而在其浮动栅极中注入热载流子来擦除。 通过选择所有数字行（DL1至DLn）并向所有字线（WL1至WLm）提供第二字线电压，通过读出放大器（8）进行抑制鉴别。

公开(公告)号：US5543877A

公开(公告)日：1996-08-06

申请号：US262853

申请日：1994-06-20

申请人： Shinya Takashi ,  Nobuyuki Tanaka

发明人： Shinya Takashi ,  Nobuyuki Tanaka

IPC分类号： G03B17/42 ,  G03B1/18

CPC分类号： G03B17/425

摘要： An automatic film feed camera includes a fork which engages a film cartridge spool to drive film out of the cartridge. When a camera cover closes a film cartridge chamber, the motor driving the fork is energized. If a detector fails to detect proper loading of a cartridge within a given time limit, the motor is turned off. When proper film loading is detected, pulses generated by a rotation detector are counted, representing the quantity of film sent toward the take-up spool. When this count reaches a predetermined quantity, driving of the fork is stopped, and driving of a take-up spool is started. If the detection device for detecting rotation of the fork fails to generate pulses indicating rotation of the fork within a given time limit after initiation of driving the take-up spool, driving of the take-up spool is stopped and the film is rewound into the cartridge by driving the fork in a reverse direction in accordance with the count represented by the sent quantity of film.

摘要翻译： 一种自动胶片馈送照相机包括一个与暗盒卷轴啮合以将胶片从盒中驱出的叉子。 当相机盖关闭暗盒时，驱动叉的电机通电。 如果检测器在给定的时间内无法检测到盒的正确装载，则电机关闭。 当检测到适当的胶片装载时，对由旋转检测器产生的脉冲进行计数，表示送往卷取卷筒的胶片的数量。 当该计数达到预定量时，停止叉子的驱动，开始卷取卷轴的驱动。 如果用于检测叉的旋转的检测装置在开始驱动卷取卷轴之后在给定的时间限制内产生指示叉的旋转的脉冲，则停止卷取卷轴的驱动，并将胶片倒回到 根据由胶片发送量表示的计数，以相反的方向驱动叉子。