公开(公告)号：US5478950A

公开(公告)日：1995-12-26

申请号：US284545

申请日：1994-08-08

Applicant: Manfred Bergfeld ,  Gunter Wiesgickl

Inventor： Manfred Bergfeld ,  Gunter Wiesgickl

IPC: B01J23/86 ,  B01J29/035 ,  B01J29/08 ,  B01J29/83 ,  B01J29/85 ,  C07B61/00 ,  C07D201/08 ,  C07D207/267 ,  C07D315/00

CPC classification number: C07D315/00 ,  C07D201/08

Abstract: The invention relates to a process for producing pyrrolidone and N-alkyl pyrrolidones from saturated or unsaturated 1,4-dicarboxylic acids or their anhydrides, hydrogen, and a primary amine, characterized in that the dicarboxylic acid or its anhydride is allowed to react in an appropriate reactor with hydrogen or ammonia via a first catalyst bed and the unisolated intermediate product is subsequently reacted with the primary amine or ammonia directly via a second, downstream catalyst bed.

Abstract translation: PCT No.PCT / EP93 / 00239 Sec。 371日期1994年8月8日 102（e）日期1994年8月8日PCT提交1993年2月3日PCT公布。 出版物WO93 / 16042 日本公开日1993年8月19日。本发明涉及由饱和或不饱和1,4-二羧酸或其酸酐，氢和伯胺生产吡咯烷酮和N-烷基吡咯烷酮的方法，其特征在于二羧酸或其 使酸酐在合适的反应器中通过第一催化剂床与氢气或氨反应，然后将非分离的中间产物与伯胺或氨直接经由第二下游催化剂​​床反应。

公开(公告)号：US4420620A

公开(公告)日：1983-12-13

申请号：US325449

申请日：1981-11-27

Applicant: Jawad H. Murib

Inventor： Jawad H. Murib

IPC: C07D201/08 ,  C07D207/26 ,  C07D207/267 ,  C07D207/27

CPC classification number: C07D207/267 ,  C07D201/08 ,  C07D207/27

Abstract: 2-pyrrolidone and N-substituted 2-pyrrolidones such as N-methyl 2-pyrrolidone and N-(beta-hydroxyethyl)-2-pyrrolidone are prepared by the catalyzed reaction of methyl 4-oxobutyrate with ammonia or a primary amine and hydrogen.

Abstract translation: 2-吡咯烷酮和N-取代的2-吡咯烷酮如N-甲基2-吡咯烷酮和N-（β-羟乙基）-2-吡咯烷酮是通过4-氨基丁酸甲酯与氨或伯胺和氢气的催化反应来制备的。

公开(公告)号：US4349473A

公开(公告)日：1982-09-14

申请号：US199218

申请日：1980-10-21

Applicant: Pier P. Rossi ,  Mario Catoni

Inventor： Pier P. Rossi ,  Mario Catoni

IPC: C07D201/16 ,  B01J19/18 ,  C07D201/08 ,  C07D201/10

CPC classification number: C07D201/10 ,  B01J19/1862 ,  C07D201/08 ,  B01J2219/00058 ,  B01J2219/00094 ,  B01J2219/00128

Abstract: Process for the preparation of .omega.-lactams (in particular caprolactam)ith improved yields, by reaction of cycloaliphatic derivatives having the general formula: ##STR1## wherein n=3-13 with nitrosating agents in the presence of dehydrating agents, characterized by the fact that the reaction is carried out a low temperature which is constant between stages, and in all the zones of a stage and with particular concentrations of the dehydrating agent.

Abstract translation: 通过在脱水剂存在下，通过使具有以下通式的脂环族衍生物（其中n = 3-13）与亚硝化剂反应制备具有改善产率的ω-内酰胺（特别是己内酰胺）的方法，其特征在于： 反应进行阶段之间恒定的低温，在一个阶段的所有区域和特定浓度的脱水剂中进行。

公开(公告)号：US4279820A

公开(公告)日：1981-07-21

申请号：US136115

申请日：1980-03-27

Applicant: Johannes G. M. Nieuwkamp

Inventor： Johannes G. M. Nieuwkamp

IPC: C07D207/26 ,  B01J23/78 ,  C07D201/08 ,  C07D207/263 ,  C07D207/38

CPC classification number: C07D201/08

Abstract: 2-pyrrolidones are prepared by hydrogenating a succinonitrile in the liquid phase in the presence of ammonia by passing an ammoniacal solution of a succinonitrile over a fixed bed catalyst, particularly of the trickle-phase type, in which the catalyst is nickel on an alkaline support such as calcium hydroxide or calcium carbonate. Attractive yields are achieved without the expense of filtering off and separating used catalyst as in prior procedures.

Abstract translation: 通过使琥珀腈的氨溶液通过固定床催化剂，特别是涓流相类型的催化剂为镍的碱性载体上的氨水溶液，在氨的存在下，通过在液相中氢化丁二腈而制备2-吡咯烷酮 例如氢氧化钙或碳酸钙。 无需像过去的程序那样过滤和分离使用过的催化剂，就可以实现有吸引力的产率。

公开(公告)号：US4250093A

公开(公告)日：1981-02-10

申请号：US53606

申请日：1979-06-29

Applicant: Frederick A. Pesa ,  Anne M. Graham

Inventor： Frederick A. Pesa ,  Anne M. Graham

IPC: C07D223/10 ,  B01J23/00 ,  B01J23/64 ,  B01J23/84 ,  B01J23/89 ,  C07B61/00 ,  C07D201/02 ,  C07D201/08 ,  C07D207/263 ,  C07D211/76

CPC classification number: B01J37/16 ,  B01J23/462 ,  B01J23/64 ,  B01J23/84 ,  B01J23/89 ,  B01J23/8906 ,  C07D201/08

Abstract: Five, six and seven member nitrogen-containing saturated heterocyclic compounds can be prepared by the catalytic hydrogenation/cyclization of beta, gamma and delta-cyanoesters. Applicants have discovered that this reaction is especially effective when it is conducted in the presence of catalysts comprising at least one of ruthenium and iron.

Abstract translation: 可以通过β，γ和δ-氰酯的催化氢化/环化制备五，六和七元含氮饱和杂环化合物。 申请人已经发现，当在包含钌和铁中的至少一种的催化剂存在下进行时，该反应特别有效。

公开(公告)号：USB506148I5

公开(公告)日：1976-02-03

申请号：US50614874

申请日：1974-09-16

IPC: C07D201/08

CPC classification number: C07D201/08

公开(公告)号：US3825570A

公开(公告)日：1974-07-23

申请号：US19503271

申请日：1971-11-02

Applicant: TEIJIN LTD

Inventor： YOSHISATO E ,  HONDA Y ,  ISHIMARU K ,  FUJITA Y ,  NARUCHI T

IPC: B01J23/72 ,  B01J23/74 ,  B01J23/86 ,  C07D201/08 ,  C07D9/00

CPC classification number: B01J23/72 ,  B01J23/74 ,  B01J23/868 ,  C07D201/08

Abstract: A PROCESS FOR THE PREPARATION OF E-CAPROLACTONE WHICH COMPRISES HEATING AT LEAST ONE AMIDE SELECTED FROM THE GROUP CONSISTING OF E-HYDROXYCAPROAMIDE AND AMIDES OF LOW POLYMERIZATION PRODUCTS OF E-HYDROXYCAPROIC ACID, IN THE PRESENCE OF AN ALCOHOLIC COMPOUND CONTAINING AT LEAST ONE FREE ALCOHOLIC HYDROXYL GROUP IN ITS MOLECULE, IN AN AMOUNT SUCH THAT, WHEN ONE E-HYDROXYCAPROIC ACID UNIT OF THE FORMULA #O-(CH2)5CO$ CONTAINED IN THE AMIDE IS CALCULATED AS ONE MOLECULE OF E-HYDROXYCAPROIC ACID, THE TOTAL NUMBER OF FREE ALCOHOLIC HYDROXYL GROUPS PRESENT IN THE REACTION SYSTEM EXCEEDS THE TOTAL NUMBER OF CARBOXYL GROUPS PRESENT IN THE REACTION SYSTEM, UNDER SUCH TEMPERATURE AND PRESSURE CONDITIONS TO ALLOW DISTILLATION OF E-CAPROLACTONE.

公开(公告)号：US3775431A

公开(公告)日：1973-11-27

申请号：US3775431D

申请日：1970-12-30

Applicant: MOBIL OIL CORP

Inventor： RODEWALD P

IPC: C07D201/08 ,  C07D207/26 ,  C07D207/267 ,  C07D207/27 ,  C10L1/232 ,  C07D27/08

CPC classification number: C07D207/267 ,  C07D201/08 ,  C07D207/27 ,  C10L1/232 ,  C10L10/08 ,  C10M1/08 ,  C10M2201/041 ,  C10M2201/14 ,  C10M2209/103 ,  C10M2215/08 ,  C10M2215/082 ,  C10M2215/102 ,  C10M2215/28 ,  C10M2229/02 ,  C10M2229/05 ,  C10N2250/10

Abstract: $-SUBSTITUTED-$-BUTYROLACTAMS ARE SYNTHESIZED AS NEW COMPOSITIONS OF MATTER. THESE COMPOUNDS ARE SYNTHESIZED BY REACTING A SUBSTUTED $-LACTONE WITH AMMONIA OR A PRIMARY AMINE AT A TEMPERATURE FROM ABOUT 200*C TO ABOUT 500*C. OVER CERTAIN ZEOLITE CATALYSTS. ADDITIONALLY, $-BUTYROLACTONE CAN BE REACTED WITH AMMONIA OVER ZEOLITE CATALYSTS IN THE ABOVE TEMPERATURE RANGE TO PRODUCE $-BUTYROLACTAM.

公开(公告)号：US3767644A

公开(公告)日：1973-10-23

申请号：US3767644D

申请日：1971-12-27

Applicant: ASAHI CHEMICAL IND

Inventor： FUKUOKA Y ,  SASAKI K

IPC: C07D223/10 ,  B01J27/00 ,  C07B61/00 ,  C07D201/08 ,  C07D207/27 ,  C07D211/76 ,  C07D41/06

CPC classification number: C07D201/08

Abstract: AN IMPROVED PROCESS FOR THE PREPARATION OF N-ALKYL SUBSTITUTED LACTAMS USEFUL AS SOLVENTS BY HEATING A CYANHYDRIN REPRESENTED BY THE FORMULA HO(CH2)NCN WHEREIN N IS AN INTEGER OF 3 TO 5 INCLUSIVE TOGETHER WITH AN ALCOHOL REPRESENTED BY THE FORMULA ROH WHEREIN R REPRESENTS AN AKYL GROUP HAVING 1 TO 4 CARBON ATOMS AT A TEMPERATURE OF 250*C. TO 400*C. UNDER PRESSURE. THE PRESENT PROCESS GIVES AN IMPROVED YIELD OF THE DESIRED PRODUCT AT A LOW COST AS COMPARED WITH THE PRIOR ART PROCESS. THE PROCESS CAN BE ADVANTAGEOUSLY MODIFIED. ONE MODIFICATION CONSISTS IN THE PROCESS OF A SPECIFIC CATALYST. ANOTHER MODIFICATION CONSISTS IN THE PROCESS IN WHICH AS LEAST A PART OF THE BY-PRODUCTS ARE RECYCLED IN THE REACTION SYSTEM. STILL ANOTHER MODIFICATION CONSISTS IN THE PROCESS IN WHICH THE REACTION IS CONDUCTED IN THE PRESENCE OF WATER, THE WATER BEING ADDED AT THE TIME OF INITIATION OF THE REACTION. SUCH MODIFICATIONS GIVE A FURTHER IMPROVED YIELD OF THE DESIRED PRODUCT.

公开(公告)号：US3658810A

公开(公告)日：1972-04-25

申请号：US3658810D

申请日：1969-08-29

Applicant: TEIJIN LTD

Inventor： TANAKA IKUZO ,  UEHARA HIDEO ,  TANAKA MAKOTO

IPC: C07D201/08 ,  C07D41/06

CPC classification number: C07D201/08

Abstract: A PROCESS FOR THE PREPARATION OF E-CAPROLACTAM BY CONTACTING CONTINUOUSLY WITH STEAM E-AMINOCAPROIC ACID, E-CAPROAMIDE OR A MIXTURE OF THE TWO AT A TEMPERATURE OF 150-400*C., WHILE DISCHARGING THE STEAM FROM THE REACTION SYSTEM. IN THIS PROCESS A SUBSTANCE NON-VOLATILE AND ACIDIC UNDER REACTION CONDITIONS CAN BE PREFERABLY USED AS CATALYST. BY THIS PROCESS, E-CAPROLACTAM CAN BE PRODUCED WITH HIGH YIELD WITHOUT FORMATION OF AMMONIUM SULFATE.