公开(公告)号：US20070038290A1

公开(公告)日：2007-02-15

申请号：US11205254

申请日：2005-08-15

Applicant: Bin Huang ,  David Gale ,  Srinivasan Sridharan ,  Joseph Callol ,  Klaus Kleine ,  Syed Hossainy ,  Timothy Limon ,  Anthony Abbate

Inventor： Bin Huang ,  David Gale ,  Srinivasan Sridharan ,  Joseph Callol ,  Klaus Kleine ,  Syed Hossainy ,  Timothy Limon ,  Anthony Abbate

IPC: A61F2/88 ,  A61F2/90 ,  B29C47/20

CPC classification number: A61F2/915 ,  A61F2/04 ,  A61F2/06 ,  A61F2/90 ,  A61F2/91 ,  A61F2002/072 ,  A61F2002/91508 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2210/0009 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2230/0013 ,  A61F2250/0098 ,  A61L31/129 ,  B23K26/402 ,  B23K26/50 ,  B23K2103/42 ,  B23K2103/50 ,  B29C43/02 ,  B29C45/0001 ,  B29C45/0005 ,  B29C45/0055 ,  B29C48/0022 ,  B29C48/022 ,  B29C48/09 ,  B29C48/10 ,  B29C48/18 ,  B29C48/2886 ,  B29C53/566 ,  B29C53/583 ,  B29C59/02 ,  B29C59/021 ,  B29C2043/028 ,  B29K2101/00 ,  B29K2105/12 ,  B29K2267/043 ,  B29K2995/0056 ,  B29K2995/006 ,  B29L2023/003 ,  B29L2031/7546 ,  D03D3/02

Abstract: Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed.

Abstract translation: 公开了用纤维增强的用于植入体腔的聚合复合支架。

公开(公告)号：US20070020381A1

公开(公告)日：2007-01-25

申请号：US11527893

申请日：2006-09-26

Applicant: Syed Hossainy ,  Gordon Stewart ,  Mark Williams ,  Jeff Royal ,  Paul Consigny ,  Dorie Happ ,  Kurt Scheinpflug ,  Ty Hu

Inventor： Syed Hossainy ,  Gordon Stewart ,  Mark Williams ,  Jeff Royal ,  Paul Consigny ,  Dorie Happ ,  Kurt Scheinpflug ,  Ty Hu

IPC: A61L33/00

CPC classification number: A61F2/844 ,  A61F2250/0067 ,  A61L27/54 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/602 ,  A61L2300/606

Abstract: A method and coating for reducing the release rate of an active agent from an implantable device, such as a stent, is disclosed.

Abstract translation: 公开了一种用于降低活性剂从可植入装置（例如支架）的释放速率的方法和涂层。

公开(公告)号：US20070009565A1

公开(公告)日：2007-01-11

申请号：US11178196

申请日：2005-07-08

Applicant: Stephen Pacetti ,  Syed Hossainy

Inventor： Stephen Pacetti ,  Syed Hossainy

IPC: A61F2/02 ,  B05D3/02

CPC classification number: A61L31/10 ,  A61L31/14 ,  C08F8/00 ,  C08F8/04 ,  C08F8/40 ,  C08F8/48 ,  Y10T428/1393 ,  C08L101/04 ,  C08F214/22

Abstract: Provided herein are methods for functionalizing an polymer for forming a coating and coatings and devices formed thereof or for functionalizing a coating or device surface including an polymer.

Abstract translation: 本文提供了用于官能化用于形成涂层的聚合物和由其形成的涂层和装置或用于官能化包括聚合物的涂层或装置表面的方法。

公开(公告)号：US20060246108A1

公开(公告)日：2006-11-02

申请号：US11117813

申请日：2005-04-29

Applicant: Stephen Pacetti ,  Syed Hossainy ,  David Gale

Inventor： Stephen Pacetti ,  Syed Hossainy ,  David Gale

IPC: A61F2/00 ,  C08L67/00

CPC classification number: A61L31/10 ,  A61L31/06 ,  A61L31/148 ,  A61L31/16 ,  C08L101/00 ,  C09D167/04 ,  C08L67/04 ,  C08L2666/02

Abstract: Implantable devices formed of or coated with a material that includes an amorphous poly(D,L-lactide) formed of a starting material such as meso-D,L-lactide are provided. The implantable device can be used for the treatment, mitigation, prevention, or inhibition of a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.

Abstract translation: 提供由包含由诸如内消旋-D，L-丙交酯的原料形成的无定形聚（D，L-丙交酯）的材料形成或涂覆的可植入装置。 可植入装置可用于治疗，缓解，预防或抑制动脉粥样硬化，血栓形成，再狭窄，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，卵圆孔未闭，跛行， 静脉和人造移植物的吻合增殖，胆管阻塞，输尿管阻塞，肿瘤阻塞或其组合。

公开(公告)号：US20060043650A1

公开(公告)日：2006-03-02

申请号：US10928587

申请日：2004-08-26

Applicant: Syed Hossainy ,  Srinivasan Sridharan ,  James Jacobs

Inventor： Syed Hossainy ,  Srinivasan Sridharan ,  James Jacobs

IPC: B28B1/00

CPC classification number: A61L31/08 ,  A61F2/958 ,  A61F2002/9522 ,  A61M25/1027 ,  A61M2025/1031 ,  Y10S606/908

Abstract: Methods of coating a stent subsequent to mounting or crimping of the stent on a balloon of a catheter assembly are disclosed.

Abstract translation: 公开了在将支架安装或压接在导管组件的球囊上之后涂覆支架的方法。

公开(公告)号：US20060019023A1

公开(公告)日：2006-01-26

申请号：US11233991

申请日：2005-09-22

Applicant: Syed Hossainy

Inventor： Syed Hossainy

IPC: A61L33/00 ,  B05D3/00

CPC classification number: B05B3/1014 ,  A61F2/82 ,  B05B3/001 ,  B05B13/0228 ,  Y10S118/16

Abstract: A method of coating a medical device, such as a stent is provided.

Abstract translation: 提供了涂覆医疗装置如支架的方法。

公开(公告)号：US20060009840A1

公开(公告)日：2006-01-12

申请号：US11227732

申请日：2005-09-14

Applicant: Syed Hossainy

Inventor： Syed Hossainy

IPC: A61F2/06

CPC classification number: A61L27/54 ,  A61L27/34 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/254 ,  A61L2300/416 ,  A61L2300/606 ,  C08L89/06 ,  C08L89/00

Abstract: A composition that releases a therapeutic substance in response to an enzyme is disclosed. The composition can be, for example, a coating for a stent.

Abstract translation: 公开了响应于酶释放治疗物质的组合物。 组合物可以是例如支架用涂层。

公开(公告)号：US20060002974A1

公开(公告)日：2006-01-05

申请号：US11212376

申请日：2005-08-26

Applicant: Stephen Pacetti ,  Eugene Michal ,  Syed Hossainy ,  Ni Ding ,  Wouter Roorda

Inventor： Stephen Pacetti ,  Eugene Michal ,  Syed Hossainy ,  Ni Ding ,  Wouter Roorda

IPC: A61K31/737 ,  A61K31/727 ,  A61K31/728 ,  A61F2/00

CPC classification number: A61K31/727 ,  A61K31/728 ,  A61K31/737 ,  A61L31/10 ,  C08L89/00

Abstract: Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.

公开(公告)号：US20050288481A1

公开(公告)日：2005-12-29

申请号：US11187467

申请日：2005-07-22

Applicant: Jessica DesNoyer ,  Stephen Pacetti ,  Lothar Kleiner ,  Syed Hossainy ,  Yung-Ming Chen ,  Gordon Stewart ,  Gina Zhang

Inventor： Jessica DesNoyer ,  Stephen Pacetti ,  Lothar Kleiner ,  Syed Hossainy ,  Yung-Ming Chen ,  Gordon Stewart ,  Gina Zhang

IPC: A61L2/00 ,  A61L31/10 ,  A61L31/16

CPC classification number: A61L31/10 ,  A61L27/18 ,  A61L27/34 ,  A61L31/06 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/604 ,  C08L77/12

Abstract: The present invention generally encompasses a medical article, such as a medical device or coating comprising an agent or combination of agents, wherein the agent is distributed throughout a polymeric matrix. The polymeric matrix comprises an agent and a poly(ester amide) having a design that was preselected to provide a predetermined release rate of the combination of agents from the medical article.

Abstract translation: 本发明通常包括医疗制品，例如包含试剂或试剂组合的医疗装置或涂层，其中所述试剂分布在整个聚合物基质中。 聚合物基质包含试剂和聚（酯酰胺），该聚（酯酰胺）具有预设以提供来自医药制品的试剂组合的预定释放速率的设计。

公开(公告)号：US20050287184A1

公开(公告)日：2005-12-29

申请号：US10881540

申请日：2004-06-29

Applicant: Syed Hossainy ,  Gordon Stewart ,  Deborah Kilpatrick ,  Jeffrey Ellis ,  Gene Park ,  Gina Zhang ,  Paul Consigny ,  Yiwen Tang

Inventor： Syed Hossainy ,  Gordon Stewart ,  Deborah Kilpatrick ,  Jeffrey Ellis ,  Gene Park ,  Gina Zhang ,  Paul Consigny ,  Yiwen Tang

IPC: A61K31/4745 ,  A61K31/56 ,  A61L31/10 ,  A61L31/16

CPC classification number: A61L31/10 ,  A61L31/16 ,  A61L2300/222 ,  A61L2300/416 ,  A61L2300/422 ,  A61L2300/43 ,  A61L2300/45

Abstract: Drug-delivery stents capable of providing release of two or more drugs such as everolimus and estradiol are provided. The stents can be used for treating a disease such as restenosis and vulnerable plaque.

Abstract translation: 提供能够释放两种或更多种药物如依维莫司和雌二醇的药物递送支架。 支架可用于治疗诸如再狭窄和易损斑块的疾病。