公开(公告)号：US20140117239A1

公开(公告)日：2014-05-01

申请号：US14129625

申请日：2012-06-27

Applicant: Shiho Sakai ,  Tomohiro Fukuma

Inventor： Shiho Sakai ,  Tomohiro Fukuma

IPC: G01J3/42

CPC classification number: G01J3/42 ,  G01J3/06 ,  G01N21/359 ,  G01N21/94

Abstract: Provided are a drug detection device and a drug detection method that are able to compute the residual amount of a drug quickly and in a contactless manner. The drug detection device according to the present invention is for detecting a drug remaining in a target area, and includes an irradiation unit configured to irradiate a target area with a light beam including near-infrared light, a spectroscope on which reflected light from the target area is incident, a near-infrared imaging unit configured to capture a spectrum obtained through dispersion of the reflected light by the spectroscope and to generate image data, a control unit configured to process the image data, and a storage unit configured to store an equation expressing a relationship between a prescribed amount of a drug and spectral data that is based on the spectrum. The near-infrared imaging unit is configured to capture each spectrum of a predetermined number of pixels allocated within the target area, and the control unit is configured to compute average spectral data of the area by averaging the spectrums of the pixels, and to compute an amount of the drug corresponding to the average spectral data, based on the equation stored in the storage unit.

Abstract translation: 本发明提供能够快速，无接触地计算药物残留量的药物检测装置和药物检测方法。 根据本发明的药物检测装置用于检测目标区域中剩余的药物，并且包括被配置为用包含近红外光的光束照射目标区域的照射单元，其中来自目标的反射光的分光器 区域是入射的，近红外成像单元，被配置为捕获通过所述分光器的反射光的分散而获得的光谱，并生成图像数据;被配置为处理所述图像数据的控制单元;以及存储单元， 表达规定量的药物与基于光谱的光谱数据之间的关系。 近红外成像单元被配置为捕获在目标区域内分配的预定数量的像素的每个频谱，并且控制单元被配置为通过对像素的频谱进行平均来计算该区域的平均频谱数据，并且计算 根据存储在存储单元中的方程，对应于平均光谱数据的药物量。

公开(公告)号：US08675989B2

公开(公告)日：2014-03-18

申请号：US13085883

申请日：2011-04-13

Applicant: Ian S. Robinson ,  Bradley Flanders

Inventor： Ian S. Robinson ,  Bradley Flanders

IPC: G06K9/36

CPC classification number: G06K9/46 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/06 ,  G01J3/2823 ,  G01J2003/2836 ,  G06K9/0063

Abstract: A method for reducing dimensionality of hyperspectral images includes receiving a hyperspectral image having a plurality of pixels. The method may further include establishing an orthonormal basis vector set comprising a plurality of mutually orthogonal normalized members. Each of the mutually orthogonal normalized members may be associated with one of the plurality of pixels of the hyperspectral image. The method may further include decomposing the hyperspectral image into a reduced dimensionality image, utilizing calculations performed while establishing said orthonormal basis vector set. A system configured to perform the method may also be provided.

Abstract translation: 一种用于降低高光谱图像的维数的方法包括接收具有多个像素的高光谱图像。 该方法还可以包括建立包括多个相互正交的归一化成员的正交基矢量集合。 每个相互正交的标准化构件可以与高光谱图像的多个像素中的一个相关联。 该方法可以进一步包括利用在建立所述正交基本向量集合时执行的计算来将高光谱图像分解为降维的图像。 还可以提供被配置为执行该方法的系统。

公开(公告)号：US20130335737A1

公开(公告)日：2013-12-19

申请号：US13992593

申请日：2011-12-09

Applicant: John T. Stein

Inventor： John T. Stein

IPC: G01J3/02 ,  H02P29/00

CPC classification number: G01J3/0202 ,  G01J3/06 ,  G01J3/4535 ,  G05B2219/49054 ,  G11B5/5582 ,  G11B5/59694 ,  H01F7/066 ,  H01F7/1844 ,  H01F2007/1861 ,  H01F2007/1866 ,  H02P25/034 ,  H02P29/00

Abstract: Provided herein are devices, systems, and methods for electrically-augmented damping of an actuator and associated devices. In particular, electrically-augmented damping derived from measurement of voltage across an actuator and current flowing through an actuator is provided.

Abstract translation: 本文提供了用于致动器和相关联装置的电加减速的装置，系统和方法。 特别地，提供了通过致动器两端的电压的测量和流过致动器的电流导出的电增益阻尼。

公开(公告)号：US20130316467A1

公开(公告)日：2013-11-28

申请号：US13819316

申请日：2011-08-30

Applicant: Keith Carron ,  Shane Buller ,  Mark Watson

Inventor： Keith Carron ,  Shane Buller ,  Mark Watson

IPC: G01N21/65

CPC classification number: G01J3/4406 ,  G01J3/06 ,  G01J3/44 ,  G01J2003/062 ,  G01J2003/064 ,  G01N21/65 ,  G01N21/658 ,  G01N33/536 ,  G01N33/54313 ,  G01N33/54373 ,  G01N2201/0612

Abstract: A spectroscopic assay is provided. The assay comprises: a motive particle configured to move within a solution, the motive particle comprising a first analyte binding reagent for selectively binding to a target analyte; and a spectroscopic reporter particle configured to provide a predetermined spectroscopic signal in response to being interrogated by a spectrometer, the spectroscopic reporter particle comprising a second analyte binding reagent for selectively binding to the target analyte, wherein the motive particle and the spectroscopic reporter particle are configured to provide a sandwich assay in the presence of the target analyte via the first and second analyte binding reagents.

Abstract translation: 提供光谱测定。 该测定包括：构型成在溶液内移动的动力颗粒，所述动力颗粒包含用于选择性结合靶分析物的第一分析物结合试剂; 以及光谱报告颗粒，其被配置为响应于由光谱仪询问而提供预定的光谱信号，所述光谱报告颗粒包含用于选择性地结合靶分析物的第二分析物结合试剂，其中所述运动颗粒和所述光谱报告颗粒被配置 以通过第一和第二分析物结合试剂在目标分析物存在下提供夹心测定。

公开(公告)号：US20130293893A1

公开(公告)日：2013-11-07

申请号：US13932481

申请日：2013-07-01

Applicant: Pason Systems Corp.

Inventor： David Bonyuet ,  Vidi A. Saptari

IPC: G01J3/42

CPC classification number: G01J3/42 ,  G01J3/02 ,  G01J3/0235 ,  G01J3/06 ,  G01J3/32 ,  G01J2003/1247 ,  G01N21/274 ,  G01N21/314 ,  G01N21/33 ,  G01N21/3504 ,  G01N2021/3174 ,  G01N2201/129

Abstract: The invention relates to methods and systems for measuring and/or monitoring the chemical composition of a sample (e.g., a process stream), and/or detecting specific substances or compounds in a sample, using light spectroscopy such as absorption, emission and fluorescence spectroscopy. In certain embodiments, the invention relates to spectrometers with rotating narrow-band interference optical filter(s) to measure light intensity as a function of wavelength. More specifically, in certain embodiments, the invention relates to a spectrometer system with a rotatable filter assembly with a position detector rigidly attached thereto, and, in certain embodiments, the further use of various oversampling methods and techniques described herein, made particularly useful in conjunction with the rotatable filter assembly. In preferred embodiments, the rotatable filter is tilted with respect to the rotation axis, thereby providing surprisingly improved measurement stability and significantly improved control of the wavelength coverage of the filter spectrometer.

Abstract translation: 本发明涉及用于测量和/或监测样品（例如工艺流）的化学成分和/或检测样品中的特定物质或化合物的方法和系统，使用光谱如吸收，发射和荧光光谱法 。 在某些实施例中，本发明涉及具有旋转窄带干涉光学滤波器的光谱仪，以测量作为波长的函数的光强度。 更具体地说，在某些实施例中，本发明涉及一种具有可转动的过滤器组件的光谱仪系统，其中位置检测器与其刚性连接，并且在某些实施例中，进一步使用本文描述的各种过采样方法和技术，特别适用于组合 与可旋转的过滤器组件。 在优选实施例中，可旋转过滤器相对于旋转轴线倾斜，从而提供惊人的改进的测量稳定性并显着改进对过滤光谱仪的波长覆盖的控制。

公开(公告)号：US08436296B2

公开(公告)日：2013-05-07

申请号：US12613665

申请日：2009-11-06

Applicant: Jess V. Ford ,  Sean M. Christian ,  Dennis Roessler ,  Bryan W. Kasperski ,  Margaret C. Waid

Inventor： Jess V. Ford ,  Sean M. Christian ,  Dennis Roessler ,  Bryan W. Kasperski ,  Margaret C. Waid

IPC: G01V5/08

CPC classification number: G01N21/255 ,  E21B47/102 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0235 ,  G01J3/06 ,  G01J3/08 ,  G01J3/12 ,  G01J2003/1213 ,  G01N21/274 ,  G01N21/314 ,  G01N21/552 ,  G01N2021/3174 ,  G01N2201/024 ,  G02B26/0841

Abstract: A downhole fluid analysis tool has a tool housing and a fluid analysis device. The tool housing is deployable downhole and has at least one flow passage for a fluid sample. The fluid analysis device is disposed in the tool housing relative to the flow passage. Inside the device, one or more sources generate a combined input electromagnetic signal across a spectrum of wavelengths, and a routing assembly routes generated signals into the reference and measurement signals. At least one wheel having a plurality of filters is rotated to selectively interpose one or more of the filters in the paths of the reference and measurement signals.

Abstract translation: 井下流体分析工具具有工具壳体和流体分析装置。 工具外壳可在井下部署，并具有用于流体样品的至少一个流动通道。 流体分析装置相对于流路设置在工具壳体中。 在设备内部，一个或多个源在波长范围内产生组合的输入电磁信号，并且路由组件将生成的信号路由到参考和测量信号中。 旋转具有多个滤波器的至少一个轮，以选择性地将一个或多个滤波器置于参考和测量信号的路径中。

公开(公告)号：US08400627B2

公开(公告)日：2013-03-19

申请号：US12922721

申请日：2009-03-11

Applicant: Martin Jacobus Johan Jak ,  Theodorus Johannes Petrus Van Den Biggelaar ,  Eduard Johannes Meijer ,  Eugene Timmering

Inventor： Martin Jacobus Johan Jak ,  Theodorus Johannes Petrus Van Den Biggelaar ,  Eduard Johannes Meijer ,  Eugene Timmering

IPC: G01J1/42

CPC classification number: G01J1/06 ,  G01J1/02 ,  G01J1/0204 ,  G01J1/0411 ,  G01J1/0437 ,  G01J1/0448 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/0237 ,  G01J3/0256 ,  G01J3/06 ,  G01J3/505 ,  G01J3/51 ,  G01J3/513 ,  G02B13/22 ,  G02B26/004

Abstract: Proposed is a light sensor (1), comprising at least one wavelength selective photo-detector (10), a lens (20) and an aperture (30).The wavelength selective photo-detector allows detecting light within a predefined wavelength range falling on the sensor. The lens project light on the photo-detector and the aperture defines a field of view of the light sensor. The photo-detector (10), the lens (20), and the aperture (30) are arranged in a telecentric configuration. Advantageously, this allows light to impinge on the wavelength selective photo-detector within a predefined range of angles irrespective of the direction of the light incident on the aperture, thus removing the angle dependent response of the wavelength selective photo-detector.

Abstract translation: 提出了一种光传感器（1），包括至少一个波长选择性光电检测器（10），透镜（20）和孔径（30）。波长选择光电检测器允许检测在预定波长范围内的光 传感器。 光学检测器和光圈上的透镜投射光限定了光传感器的视场。 光检测器（10），透镜（20）和孔（30）以远心配置布置。 有利的是，这允许光在预定范围的角度内照射波长选择性光检测器，而与入射在孔径上的光的方向无关，从而消除波长选择性光检测器的角度相关响应。

公开(公告)号：US20130044317A1

公开(公告)日：2013-02-21

申请号：US13563794

申请日：2012-08-01

Applicant: James Justice ,  John Carson ,  Medhat Azzazy ,  Ying Hsu

Inventor： James Justice ,  John Carson ,  Medhat Azzazy ,  Ying Hsu

IPC: G01J3/45

CPC classification number: G01J3/06 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/0256 ,  G01J3/0259 ,  G01J3/0294 ,  G01J3/18 ,  G01J3/36 ,  G01J3/45 ,  G02B17/0808 ,  G02B17/0896 ,  G02B26/0808 ,  G02B26/0891 ,  G02B27/145

Abstract: A sensor suite comprising a LIDAR transmitter and receiver element and a visible imager element. The transmitter operates with a plurality of selectable beam-forming optics or a tilt-tip element. A Risley or counter-rotating prism set element permits beam-steering with lower size, weight and power (SWaP). The optics for the system may be configured in a Cassegrain-type configuration in cooperation with a plurality of beam-splitting elements to permit predetermined spectrums of the received electromagnetic spectrum to be provided respectively to the LIDAR receiver and the visible imager. One or a plurality of laser illuminator analysis spectrometers are provided for the detection of incoming laser illumination from an external source which may be in the form of a micro-lamellar spectrometer element.

Abstract translation: 传感器套件，包括LIDAR发射器和接收器元件以及可见成像元件。 发射器与多个可选择的波束形成光学器件或倾斜尖端元件一起工作。 Risley或反向旋转的棱镜组元件允许具有较小尺寸，重量和功率（SWaP）的光束转向。 该系统的光学器件可以与多个光束分离元件协作配置为卡塞格伦型配置，以允许分别向LIDAR接收器和可见成像器提供所接收的电磁光谱的预定光谱。 提供一个或多个激光照明器分析光谱仪用于检测来自外部源的输入激光照明，其可以是微片层光谱仪元件的形式。

公开(公告)号：US08294990B2

公开(公告)日：2012-10-23

申请号：US12554240

申请日：2009-09-04

Applicant: Douglas J. Brown ,  Daniel B. Mitchell ,  Geoffrey G. Harris

Inventor： Douglas J. Brown ,  Daniel B. Mitchell ,  Geoffrey G. Harris

IPC: G02B27/00 ,  G02B5/28

CPC classification number: G02B26/00 ,  G01J3/02 ,  G01J3/0262 ,  G01J3/06 ,  G01J3/12 ,  G01J2003/1213 ,  G01J2003/1243 ,  G01J2003/1247 ,  G02B5/28 ,  G02B21/16 ,  G02B26/007

Abstract: An apparatus includes an optical filter having first and second passbands that are different, the optical filter including selectively operable first passband adjusting structure that varies a characteristic of the first passband without influencing the second passband. According to a different aspect, a method includes filtering radiation with an optical filter having first and second passbands that are different, and selectively varying a characteristic of the first passband without influencing the second passband.

Abstract translation: 一种装置包括具有不同的第一和第二通带的滤光器，所述滤光器包括可选择地操作的第一通带调整结构，其改变第一通带的特性而不影响第二通带。 根据不同方面，一种方法包括利用具有不同的第一和第二通带的滤光器来过滤辐射，并且选择性地改变第一通带的特性而不影响第二通带。

公开(公告)号：US20120257037A1

公开(公告)日：2012-10-11

申请号：US13439954

申请日：2012-04-05

Applicant: Valerica Raicu ,  Thomas John Mozer ,  Uwe Richard Muller

Inventor： Valerica Raicu ,  Thomas John Mozer ,  Uwe Richard Muller

IPC: H04N7/18 ,  G06K9/00

CPC classification number: G01J3/2803 ,  G01J3/027 ,  G01J3/0294 ,  G01J3/06 ,  G01J3/4406 ,  G01N15/1434 ,  G01N15/1463 ,  G01N15/1475 ,  G01N2015/1006 ,  G02B21/002 ,  G02B21/0076 ,  G02B21/16 ,  G02B27/0927 ,  G02B27/0983

Abstract: A system and method of implementing a two-stage scanning technique with a high-speed microscope. The microscope is operable to provide spectrally resolved, multi-dimensional images from a single scan of a sample. The microscope may include one of a multi-beam point scanning microscope, a single beam line scanning microscope, and a multi-beam line scanning microscope. The sample is first tagged such that, if the sample has a particular makeup, it emits energy at particular wavelengths upon receiving excitation beams. The microscope is used to perform a first, wide area scan. If the sample is determined to have emitted energy having particular characteristics, the microscope performs a second, focused scan of the area that emitted the energy having the particular characteristics. The two-stage scanning technique is automated and may be used to quickly identify rare cells, microbes, viruses, and other components within one or more samples.

Abstract translation: 用高速显微镜实现两级扫描技术的系统和方法。 显微镜可操作以从样品的单次扫描提供光谱分辨的多维图像。 显微镜可以包括多光束点扫描显微镜，单束线扫描显微镜和多光束线扫描显微镜中的一个。 样品首先被标记，使得如果样品具有特定的组成，则在接收到激发光束时，其以特定波长发射能量。 显微镜用于执行第一次广域扫描。 如果确定样品具有具有特定特征的发射能量，则显微镜对发射具有特定特征的能量的区域进行第二次聚焦扫描。 两级扫描技术是自动化的，可用于快速识别一个或多个样品中的稀有细胞，微生物，病毒和其他成分。